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Gretchen Hermes, MD, PhD

Assistant Professor of Psychiatry; Medical Director, APT Foundation; Chief Psychiatrist, Yale Stress Center; Addiction Psychiatry Fellowship Coordinator, APT Foundation

Contact Information

Gretchen Hermes, MD, PhD

Patient Care Locations

Lab Location

  • Brady Memorial Laboratory
    310 Cedar Street, Ste 416
    New Haven, CT, 06510

Office Location

  • Doctors Building
    2 Church Street South, Fl 2nd, Ste 208, Rm 209
    New Haven, CT, 06519

Mailing Address

  • Psychiatry

    2 Church St S

    New Haven, CT, 06519

    United States



Gretchen Hermes completed her MD/PhD on pre-clinical stress-diathesis models of social neglect at the University of Chicago with Martha K. McClintock, a pioneer in the field of social neuroscience. These models of psychopathology (schizophrenia, depression) laid the foundation for her current research on molecular mechanisms that protect against the pathophysiological changes underlying abnormal brain development. This work in collaboration with the Section of Comparative Medicine and the Yale Depression Research Program focuses on the role of mitochondrial proteins in facilitating synaptic plasticity and neurotransmission, representing a potential paradigm shift toward a role for energy and biogenesis in mental illness.

Dr. Hermes is also an attending psychiatrist at the APT Foundation, a cornerstone treatment facility for Opioid Use Disorder in New Haven where she provides targeted pharmacotherapy for the full spectrum of co-morbid DSM disorders. In addition, Dr. Hermes is on the faculty of the Yale Addiction Fellowship where she teaches and supervises fellows in the Addiction Psychiatry Residency Program.

Dr. Hermes is a co-investigator at the Yale Stress Center, an interdisciplinary behavioral health facility, dedicated to applying evidence-informed practice to reduce the risk of stress-related physical and mental illnesses. The Stress Center conducts research on the science of stress, linking brain mechanisms of stress to disease, and on related interventions.

Education & Training

  • MD
    University of Chicago Pritzker School of Medicine (2007)
  • PhD
    University of Chicago (2003)
  • MA
    Harvard Divinity School (1997)
  • Research Fellowship, Schizophrenia
    Yale University
  • Residency
    Yale University
  • Postdoctoral Fellowship, NIH, Interdisciplinary Program in Immunology
    University of Chicago

Honors & Recognition

AwardAwarding OrganizationDate
NARSAD Young Investigator GrantBrain and Behavior Research Foundation2015
Workshop on Schizophrenia and Related Disorders, Travel Award and StipendCold Spring Harbor Laboratory2012
Daniel X. and Mary Freedman Fellowship in Academic PsychiatryFreedman Foundation2011
APA-Pfizer M.D., Ph.D. Research Fellowship AwardAmerican Psychiatric Association2011
Power Day Award, Psychiatry, for a resident nominated by 3rd year medical class, who serves as a true role model for Yale medical students Yale School of Medicine2011
APA-Janssen Resident Psychiatric Research ScholarAmerican Psychiatric Association2010
Seymour Lustman Award for Outstanding Resident ResearchYale Department of Psychiatry2009
ACNP Travel AwardAmerican College of Neuropsychopharmacology2008

Professional Service

Female Opioid Research and Clinical Experts (FORCE)2017 - Present
California Breast Cancer Research Program; University of California, Office of the PresidentPeer Review: Grant submissions in response to an Animal Models Initiative to Investigate Concurrent Effects of Environmental Chemicals and Stress Factors on Mammary Cancer2016 - Present
Ad Hoc ReviewerBrain, Behavior, and Immunity; Frontiers: Schizophrenia, Associate Editor; Neuropharmacology; Neuroendocrinology; Neuroscience Letters; Psychoneuroimmunolgy; Psychiatry Research; Sage OPEN Publications; Schizophrenia Research; Schizophrenia Bulletin 2008 - Present

Departments & Organizations