Th17 Cells Are Not Required for Host Defense Against Murine Disseminated Candidiasis, But Are Required for Vaccine-Mediated Protection (132.10)
Lin L, Ibrahim A, Avanesian V, Xu X, Farber J, Fu Y, Baquir B, Spellberg B. Th17 Cells Are Not Required for Host Defense Against Murine Disseminated Candidiasis, But Are Required for Vaccine-Mediated Protection (132.10). The Journal Of Immunology 2009, 182: 132.10-132.10. DOI: 10.4049/jimmunol.182.supp.132.10.Peer-Reviewed Original ResearchCCR6-deficient miceDisseminated candidiasisVaccine-mediated protectionTh17 cellsIL-17Control miceRAls3p-NVaccine efficacyDeficient miceSusceptible to disseminated candidiasisCD4+IL-17+Wild type control miceMurine disseminated candidiasisRecombinant N-terminusLevels of IFNCompare Th1Th1/17 cellsT lymphocytesUnvaccinated miceC. albicansCandidiasisVaccinated miceTail veinTh17Candidal adhesin