Gretchen Hermes, MD, PhD

Assistant Professor

Departments & Organizations

Psychiatry: Addictions, Division of | Neuroscience Research Training Program (NRTP) | Yale Stress Center

Yale Medicine


Gretchen Hermes completed her MD/PhD on pre-clinical stress-diathesis models of social neglect at the University of Chicago with Martha K. McClintock, a pioneer in the field of social neuroscience. These models of psychopathology (schizophrenia, depression) laid the foundation for her current research on molecular mechanisms that protect against the pathophysiological changes underlying abnormal brain development. This work, through the Section of Comparative Medicine and with Dr. Tamas Horvath, focuses on the role of mitochondrial proteins in facilitating synaptic plasticity and neurotransmission representing a potential paradigm shift toward a role for energy and biogenesis in mental illness.

Dr. Hermes is also the attending psychiatrist at the Yale Stress Center, an interdisciplinary behavioral health facility, dedicated to applying evidence-informed practice to reduce the risk of stress-related physical and mental illnesses. The Stress Center conducts research on the science of stress, linking brain mechanisms of stress to disease, and on related interventions. Dr. Hermes provides targeted pharmacotherapy for the full spectrum of DSM disorders.

Education & Training

MD University of Chicago Pritzker School of Medicine (2007)
PhD University of Chicago (2003)
MA Harvard Divinity School (1997)
Research Fellowship, Schizophrenia Yale University
Residency Yale University
Postdoctoral Fellowship, NIH, Interdisciplinary Program in Immunology University of Chicago

Honors & Recognition

  • NARSAD Young Investigator GrantBrain and Behavior Research Foundation (2015)

  • Workshop on Schizophrenia and Related Disorders, Travel Award and StipendCold Spring Harbor Laboratory (2012)

  • Daniel X. and Mary Freedman Fellowship in Academic PsychiatryFreedman Foundation (2011)

  • APA-Pfizer M.D., Ph.D. Research Fellowship AwardAmerican Psychiatric Association (2011)

  • Power Day Award, Psychiatry, for a resident nominated by 3rd year medical class, who serves as a true role model for Yale medical students Yale School of Medicine (2011)

  • APA-Janssen Resident Psychiatric Research ScholarAmerican Psychiatric Association (2010)

  • Seymour Lustman Award for Outstanding Resident ResearchYale Department of Psychiatry (2009)

  • ACNP Travel AwardAmerican College of Neuropsychopharmacology (2008)

Professional Service

  • Female Opioid Research and Clinical Experts (FORCE) (2017 - Present)

  • California Breast Cancer Research Program; University of California, Office of the President (2016 - Present) Peer Review: Grant submissions in response to an Animal Models Initiative to Investigate Concurrent Effects of Environmental Chemicals and Stress Factors on Mammary Cancer

  • Ad Hoc Reviewer (2008 - Present) Brain, Behavior, and Immunity; Frontiers: Schizophrenia, Associate Editor; Neuropharmacology; Neuroendocrinology; Neuroscience Letters; Psychoneuroimmunolgy; Psychiatry Research; Sage OPEN Publications; Schizophrenia Research; Schizophrenia Bulletin

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Contact Info

Gretchen Hermes, MD, PhD
Patient Care Location
Yale Depression Research Program100 York Street, Ste 2J
New Haven, CT 06511
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Lab Location
Horvath LabBrady Memorial Laboratory
310 Cedar Street, Ste 416

New Haven, CT 06510
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Mailing Address
Psychiatry2 Church St S
New Haven, CT 06519