The Yale Psychiatry Residency Journal Club is a resident-led, academic forum designed to provide faculty mentorship and peer support to residents and fellows in the evaluation of seminal papers in psychiatric research. The Journal Club emphasizes a critical appraisal of scientific evidence. The literature is evaluated in terms of its validity, reliability, study design, and biostatistical methods. Selected articles focus on highly relevant topics that continuously shape the history, epidemiology, and clinical practice of psychiatry. Topics range from basic neuroscience to the social and structural determinants of mental health. Moreover, the application of the appraised evidence to clinical practice is a cornerstone of the discussions. The Journal Club aims to encourage residents and fellows to translate clinical uncertainty into an answerable scientific question and serves as an adjunct to the residency program's stance on an evidence-based mental health curriculum. Discussions are held monthly and are facilitated by residents with the support of a faculty advisor. On occasion, the Journal Club leadership invites guests, such as authors and mental health authorities, with unique expertise on a given topic.