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ADVANCE Study FAQ

What is the purpose of this study?
To examine the use of Varenicline (Chantix) to reduce alcohol consumption in heavy drinking smokers.
What medication is being tested in this study?
The medication is called Varenicline. It is FDA-approved as a smoking cessation medication. In this study, we are examining the use of Varenicline to reduce alcohol consumption.
Will this medication make me sick if I take it while drinking?
Varenicline was not designed to cause this reaction. While nausea can occur with Varenicline, it is usually mild and typically goes away over time. A different medication, called disulfiram or antabuse is designed to make someone sick if they drink alcohol while taking it. Again, this is not the medication used in this study.
Is Varenicline safe?
Varenicline has been approved by the FDA as a smoking cessation medication. In our study, we are examining the use of Varenicline to reduce alcohol consumption. Like any medication, its use may lead to side effects such as nausea and it must be used as directed. Details about the medication and how it should be taken would be explained to you by the study nurse. You can always contact us with any questions or concerns about the medication.
How large of a dose would I take?
You will take a 2mg dose each day.
How long would I be in the study?
The study lasts about one year.
How many appointments would I have to attend?
There are a total of 17 appointments for the study over the course of a year at our study site at 1 Long Wharf Drive in New Haven.
How much money would I make?
You can earn up to $525 while participating in the ADVANCE Study.
What do I do if I want to participate?
Call us at (203) 859-8643 or email us at advance@yale.edu.

Contact Us

Call us:
203-859-8643

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Email:
advance@yale.edu

Address:
1 Long Wharf Drive, SATU, Box 18, New Haven, CT, 06511