2025
Kleptomania on the impulsive–compulsive spectrum. Clinical and therapeutic considerations for women
Munguía L, Baenas-Soto I, Granero R, Fábregas-Balcells M, Gaspar-Pérez A, Rosinska M, Potenza M, Cuquerella Á, Tapia-Martínez J, Cabús-Grange R, Taranilla-Castro A, Macharé-Alberni M, Talón-Navarro M, Fernández-Aranda F, Jiménez-Murcia S. Kleptomania on the impulsive–compulsive spectrum. Clinical and therapeutic considerations for women. Scientific Reports 2025, 15: 7886. PMID: 40050325, PMCID: PMC11885670, DOI: 10.1038/s41598-025-85705-9.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCognitive Behavioral TherapyDisruptive, Impulse Control, and Conduct DisordersFeeding and Eating DisordersFemaleHumansImpulsive BehaviorTreatment OutcomeYoung AdultConceptsImpulsive-compulsive spectrumDSM-5 criteriaClinical groupsDSM-5Personality featuresSemi-structured clinical interviewTreatment outcomesHarm avoidance scoresCognitive behavioral treatmentHealthy control individualsSample of female patientsImpact treatment outcomesPoor treatment outcomesCompulsive featuresBehavioral treatmentHigher impulsivityAvoidance scoresClinical interviewKleptomaniaInvestigate treatment outcomesCharacteristics of peopleFemale participantsPsychopathologyClinical samplesTreatment approaches
2021
Predictors of gaming disorder in children and adolescents: a school-based study
Ferreira F, Bambini B, Tonsig G, Fonseca L, Picon F, Pan P, Salum G, Jackowski A, Miguel E, Rohde L, Bressan R, Gadelha A. Predictors of gaming disorder in children and adolescents: a school-based study. Brazilian Journal Of Psychiatry 2021, 43: 289-292. PMID: 32756806, PMCID: PMC8136393, DOI: 10.1590/1516-4446-2020-0964.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBehavior, AddictiveBrazilChildDisruptive, Impulse Control, and Conduct DisordersHumansInternetSchoolsVideo GamesConceptsMental disordersWell-Being Behavior AssessmentHigh-risk cohortLogistic regression modelsSchool-based studyGaming disorderPsychiatric disordersUnhealthy patternsDisorder ratesSchool-based sampleDisordersSignificant predictorsFurther riskBrazilian High-Risk CohortCommunity sampleHigh rateBehavior changeMore hoursRegression modelsChildrenPredictorsAdolescentsHoursBehavior assessmentPattern variables
2018
Dual diagnosis of obsessive compulsive and compulsive buying disorders: Demographic, clinical, and psychiatric correlates
Kim H, Hodgins D, Torres A, Fontenelle L, do Rosário M, de Mathis M, Ferrão Y, Miguel E, Tavares H. Dual diagnosis of obsessive compulsive and compulsive buying disorders: Demographic, clinical, and psychiatric correlates. Comprehensive Psychiatry 2018, 86: 67-73. PMID: 30081209, DOI: 10.1016/j.comppsych.2018.07.013.Peer-Reviewed Original ResearchMeSH KeywordsAdultBinge-Eating DisorderComorbidityCompulsive BehaviorConsumer BehaviorDiagnosis, Dual (Psychiatry)Disruptive, Impulse Control, and Conduct DisordersFemaleHoardingHumansMaleMiddle AgedObsessive-Compulsive DisorderPsychiatric Status Rating ScalesYoung AdultConceptsCompulsive buying disorderObsessive-compulsive disorderBuying disorderComorbid obsessive-compulsive disorderDual diagnosisUnique clinical populationInternet use disordersDual diagnosis populationPsychiatric correlatesPsychiatric disordersPsychological mechanismsSocial phobiaOCD symptomsStructured Clinical InterviewClinical populationsSound measureLarge multi-centre studyClinical InterviewProtective factorsMulti-center studyUse disordersPresent researchTreatment utilityBinary logistic regressionCorrelates
2017
Genome-Wide DNA Methylation Changes Associated with Intermittent Explosive Disorder: A Gene-Based Functional Enrichment Analysis
Montalvo-Ortiz JL, Zhang H, Chen C, Liu C, Coccaro EF. Genome-Wide DNA Methylation Changes Associated with Intermittent Explosive Disorder: A Gene-Based Functional Enrichment Analysis. The International Journal Of Neuropsychopharmacology 2017, 21: 12-20. PMID: 29106553, PMCID: PMC5789263, DOI: 10.1093/ijnp/pyx087.Peer-Reviewed Original ResearchMeSH KeywordsAdultDisruptive, Impulse Control, and Conduct DisordersDNA MethylationEpigenesis, GeneticEpigenomicsFemaleGene Regulatory NetworksGenome-Wide Association StudyHumansMaleMiddle AgedPsychiatric Status Rating ScalesConceptsGenome-wide DNA methylation changesFunctional enrichment analysisDNA methylation changesEnrichment analysisCpG sitesMethylation changesGenome-wide significant thresholdIllumina Infinium HumanMethylation450 BeadChipBlood DNA methylomeNovel biological processesInfinium HumanMethylation450 BeadChipDNA methylomeEpigenetic mechanismsPathway analysisBiological processesGenetic studiesNeuronal differentiationHumanMethylation450 BeadChipGenesBehavioral genetic studiesR packageImportant mechanismGenetic influencesEndocrine systemMethylome
2016
Systematic Review of Pharmacological and Behavioral Treatments for Skin Picking Disorder
Schumer MC, Bartley CA, Bloch MH. Systematic Review of Pharmacological and Behavioral Treatments for Skin Picking Disorder. Journal Of Clinical Psychopharmacology 2016, 36: 147-152. PMID: 26872117, PMCID: PMC4930073, DOI: 10.1097/jcp.0000000000000462.Peer-Reviewed Original ResearchMeSH KeywordsBehavior TherapyDisruptive, Impulse Control, and Conduct DisordersHumansMental DisordersRandomized Controlled Trials as TopicSelective Serotonin Reuptake InhibitorsSelf-Injurious BehaviorSkin DiseasesTreatment OutcomeConceptsInactive control conditionsUncontrolled trialsBehavioral treatmentSystematic reviewLarger placebo-controlled RCTsSelective serotonin reuptake inhibitorsShort-term clinical trialsBehavioral interventionsPlacebo-controlled RCTsSerotonin reuptake inhibitorsSkin picking disorderEfficacy of treatmentNovel pharmacological agentsShort-term trialsReuptake inhibitorsTreatment armsControl conditionClinical trialsDemonstrated efficacyPsychiatric disordersPharmacological agentsSignificant improvementElectronic databasesRCTsMeta-Analysis
2015
Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease
Weintraub D, Simuni T, Caspell‐Garcia C, Coffey C, Lasch S, Siderowf A, Aarsland D, Barone P, Burn D, Chahine M, Eberling J, Espay AJ, Foster ED, Leverenz JB, Litvan I, Richard I, Troyer MD, Hawkins KA, Initiative T. Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease. Movement Disorders 2015, 30: 919-927. PMID: 25737166, PMCID: PMC4855523, DOI: 10.1002/mds.26170.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnxietyApathyBiomarkersCognition DisordersCognitive DysfunctionDepressionDisruptive, Impulse Control, and Conduct DisordersFemaleHumansMaleMental DisordersMiddle AgedParkinson DiseasePrevalencePsychotic DisordersSeverity of Illness IndexConceptsParkinson's Progression Markers InitiativeNeuropsychiatric symptomsPD patientsHealthy controlsProgression Markers InitiativeParkinson's diseaseCognitive impairmentUntreated PD patientsDopamine replacement therapySignificant depressive symptomsGroup differencesSymptoms of depressionQuality of lifeMild cognitive impairmentUntreated patientsDisease courseReplacement therapyICD symptomsControl disordersDepressive symptomsGeneral populationPatientsMeeting criteriaMulti-site studyBiological predictors
2012
‘Impulsive compulsivity’ in obsessive-compulsive disorder: A phenotypic marker of patients with poor clinical outcome
Kashyap H, Fontenelle L, Miguel E, Ferrão Y, Torres A, Shavitt R, Ferreira-Garcia R, do Rosário M, Yücel M. ‘Impulsive compulsivity’ in obsessive-compulsive disorder: A phenotypic marker of patients with poor clinical outcome. Journal Of Psychiatric Research 2012, 46: 1146-1152. PMID: 22647523, DOI: 10.1016/j.jpsychires.2012.04.022.Peer-Reviewed Original ResearchMeSH KeywordsAdultDisruptive, Impulse Control, and Conduct DisordersFemaleHumansMaleMiddle AgedObsessive-Compulsive DisorderPsychiatric Status Rating ScalesRetrospective StudiesSeverity of Illness IndexStatistics, NonparametricSurveys and QuestionnairesYoung Adult
2011
Skin picking and trichotillomania in adults with obsessive-compulsive disorder
Lovato L, Ferrão Y, Stein D, Shavitt R, Fontenelle L, Vivan A, Miguel E, Cordioli A. Skin picking and trichotillomania in adults with obsessive-compulsive disorder. Comprehensive Psychiatry 2011, 53: 562-568. PMID: 22014580, DOI: 10.1016/j.comppsych.2011.06.008.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionBody Dysmorphic DisordersBrazilCase-Control StudiesComorbidityCross-Sectional StudiesDisruptive, Impulse Control, and Conduct DisordersEducationFemaleHumansLogistic ModelsMaleObsessive-Compulsive DisorderPrevalenceSex DistributionTrichotillomaniaConceptsPathologic skin pickingObsessive-compulsive disorderSkin pickingFourth Edition Axis IEdition Axis IStructured Clinical InterviewLogistic regression analysisComorbid body dysmorphic disorderBody dysmorphic disorderClinical characteristicsSuch comorbiditiesPrimary diagnosisAxis IClinical InterviewSpecific subgroupsMental disordersDysmorphic disorderStatistical ManualTrichotillomaniaDisordersCompulsive symptomsPatientsRegression analysisDiagnosisHigh levelsSuicidality in obsessive-compulsive disorder: prevalence and relation to symptom dimensions and comorbid conditions.
Torres A, Ramos-Cerqueira A, Ferrão Y, Fontenelle L, do Rosário M, Miguel E. Suicidality in obsessive-compulsive disorder: prevalence and relation to symptom dimensions and comorbid conditions. The Journal Of Clinical Psychiatry 2011, 72: 17-26; quiz 119-20. PMID: 21272513, DOI: 10.4088/jcp.09m05651blu.Peer-Reviewed Original ResearchMeSH KeywordsAdultComorbidityCross-Sectional StudiesDepressive Disorder, MajorDisruptive, Impulse Control, and Conduct DisordersFemaleHumansLongitudinal StudiesMaleObsessive-Compulsive DisorderPersonality InventoryPrevalenceReligion and PsychologyRisk FactorsSexual BehaviorStress Disorders, Post-TraumaticSuicideSuicide, AttemptedSurveys and QuestionnairesConceptsPosttraumatic stress disorderMajor depressive disorderObsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleCurrent suicidal thoughtsSubstance use disordersImpulse control disordersSuicidal thoughtsObsessive Compulsive ScaleDepressive disorderUse disordersDSM-IV Axis I DisordersSuicidal behaviorComorbid substance use disorderCompulsive ScaleOCD patientsLifetime major depressive disorderCross-sectional studyStructured Clinical InterviewAxis I DisordersLogistic regression analysisPrimary obsessive-compulsive disorderSymptom dimensionsLifetime suicidal thoughtsBrazilian Research ConsortiumStealing among high school students: prevalence and clinical correlates.
Grant JE, Potenza MN, Krishnan-Sarin S, Cavallo DA, Desai RA. Stealing among high school students: prevalence and clinical correlates. The Journal Of The American Academy Of Psychiatry And The Law 2011, 39: 44-52. PMID: 21389165, PMCID: PMC3671850.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent BehaviorConnecticutDisruptive, Impulse Control, and Conduct DisordersFemaleHumansMaleSchoolsStudentsSurveys and QuestionnairesTheft
2010
Selective Cocaine‐Related Difficulties in Emotional Intelligence: Relationship to Stress and Impulse Control
Fox HC, Bergquist KL, Casey J, Hong KA, Sinha R. Selective Cocaine‐Related Difficulties in Emotional Intelligence: Relationship to Stress and Impulse Control. American Journal On Addictions 2010, 20: 151-160. PMID: 21314758, PMCID: PMC3166613, DOI: 10.1111/j.1521-0391.2010.00108.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCase-Control StudiesCocaine-Related DisordersDisruptive, Impulse Control, and Conduct DisordersEmotional IntelligenceHumansIntelligence TestsMaleMiddle AgedStress, PsychologicalConceptsEmotional intelligenceCocaine-dependent individualsCocaine-dependent participantsCaruso Emotional Intelligence TestDependent individualsDependent participantsEmotional Intelligence TestRegulation of emotionMeasures of IQRelapse-related factorsEmotional reasoningIQ factorsIntelligence testsStress dysregulationImpulse controlStress perceptionHealthy controlsCocaine patientsControl difficultiesEmotionsIQCurrent studySpecific aspectsRisk-related factorsEI problemsVideo-Gaming Among High School Students: Health Correlates, Gender Differences, and Problematic Gaming
Desai RA, Krishnan-Sarin S, Cavallo D, Potenza MN. Video-Gaming Among High School Students: Health Correlates, Gender Differences, and Problematic Gaming. 2010, 126: e1414-e1424. PMID: 21078729, PMCID: PMC3678538, DOI: 10.1542/peds.2009-2706.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent BehaviorBehavior, AddictiveConnecticutDisruptive, Impulse Control, and Conduct DisordersFemaleHealth StatusHumansMalePrevalencePsychometricsSex DistributionSex FactorsSurveys and QuestionnairesVideo GamesConceptsProblematic gamingHealth correlatesMore externalizing behaviorsVideo game playingInternalizing symptomsHigh school studentsExternalizing behaviorsRegular cigarette smokingSerious fightNegative health correlatesGame playingIntervention strategiesGender differencesSchool studentsCorrelatesGamingHealth behaviorsHealth factorsDrug useGirlsBoysMore researchDepressionAggressionAdolescentsRefining the diagnostic boundaries of compulsive hoarding: A critical review
Pertusa A, Frost RO, Fullana MA, Samuels J, Steketee G, Tolin D, Saxena S, Leckman JF, Mataix-Cols D. Refining the diagnostic boundaries of compulsive hoarding: A critical review. Clinical Psychology Review 2010, 30: 371-386. PMID: 20189280, DOI: 10.1016/j.cpr.2010.01.007.Peer-Reviewed Original ResearchCompulsive BehaviorCompulsive Personality DisorderDiagnosis, DifferentialDisruptive, Impulse Control, and Conduct DisordersHumansObsessive BehaviorObsessive-Compulsive DisorderPsychiatric Status Rating Scales
2009
A cross-sectional study of problem and pathological gambling in patients with schizophrenia/schizoaffective disorder.
Desai RA, Potenza MN. A cross-sectional study of problem and pathological gambling in patients with schizophrenia/schizoaffective disorder. The Journal Of Clinical Psychiatry 2009, 70: 1250-7. PMID: 19538900, PMCID: PMC3695825, DOI: 10.4088/jcp.08m04359.Peer-Reviewed Original ResearchMeSH KeywordsCommunity Mental Health CentersComorbidityConnecticutCross-Sectional StudiesDisruptive, Impulse Control, and Conduct DisordersFemaleGamblingHumansMaleMiddle AgedPrevalencePsychiatric Status Rating ScalesPsychotic DisordersSchizophreniaSocioeconomic FactorsUnited StatesConceptsSchizophrenia/schizoaffective disorderProblem/pathological gamblingSchizoaffective disorderPsychotic disordersPathological gamblingGreater alcohol use severityVA Connecticut Healthcare SystemConnecticut Mental Health CenterMental health care utilizationHealth care utilizationCross-sectional studyMental health centersHigher depression scoresLogistic regression modelsAlcohol use severityMultinomial logistic regression modelsAlcohol use problemsCare utilizationClinical correlatesOutpatient subjectsHealth centersMultivariable modelHigh riskImproved preventionDepression scoresRisk/reward decision-making in schizophrenia: A preliminary examination of the influence of tobacco smoking and relationship to Wisconsin Card Sorting Task performance
Yip SW, Sacco KA, George TP, Potenza MN. Risk/reward decision-making in schizophrenia: A preliminary examination of the influence of tobacco smoking and relationship to Wisconsin Card Sorting Task performance. Schizophrenia Research 2009, 110: 156-164. PMID: 19269138, PMCID: PMC2817985, DOI: 10.1016/j.schres.2009.01.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognition DisordersDecision MakingDisruptive, Impulse Control, and Conduct DisordersFemaleGamblingHumansMaleMiddle AgedNeuropsychological TestsPsychiatric Status Rating ScalesRewardRiskSchizophreniaSchizophrenic PsychologySex FactorsSmokingYoung AdultConceptsWisconsin Card Sorting TaskIowa Gambling TaskTask performanceCard Sorting TaskSchizophrenia show deficitsRisk/rewardNon-psychiatric controlsNeurocognitive tasksGambling TaskCognitive functioningIGT performanceSorting TaskWCST performanceComputerized versionRisk/TaskSchizophreniaDeficitsMixed resultsSubject groupsPreliminary examinationIndividualsClinical factorsFurther researchTobacco smokingDifferences in Characteristics of Asian American and White Problem Gamblers Calling a Gambling Helpline
Barry DT, Steinberg MA, Wu R, Potenza MN. Differences in Characteristics of Asian American and White Problem Gamblers Calling a Gambling Helpline. CNS Spectrums 2009, 14: 83-91. PMID: 19238123, PMCID: PMC2651150, DOI: 10.1017/s1092852900000237.Peer-Reviewed Original Research
2008
Self-Mutilation: A Symptom of Psychiatric Disorder or a Nosological Entity with its Own Characteristics?
Giusti J, Tavares H, Miguel E, Scivoletto S. Self-Mutilation: A Symptom of Psychiatric Disorder or a Nosological Entity with its Own Characteristics? CNS Spectrums 2008, 13: 273-274. PMID: 18408645, DOI: 10.1017/s1092852900016369.Peer-Reviewed Original ResearchBorderline Personality DisorderComorbidityDisruptive, Impulse Control, and Conduct DisordersHumansObsessive-Compulsive DisorderPersonality AssessmentSelf MutilationObsessive–compulsive disorder: Influence of age at onset on comorbidity patterns
de Mathis M, do Rosario M, Diniz J, Torres A, Shavitt R, Ferrão Y, Fossaluza V, de Bragança Pereira C, Miguel E. Obsessive–compulsive disorder: Influence of age at onset on comorbidity patterns. European Psychiatry 2008, 23: 187-194. PMID: 18329252, DOI: 10.1016/j.eurpsy.2008.01.002.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge of OnsetAnxiety DisordersAttention Deficit Disorder with HyperactivityBrazilComorbidityCross-Sectional StudiesDisruptive, Impulse Control, and Conduct DisordersFeeding and Eating DisordersFemaleHumansMaleMental DisordersMiddle AgedObsessive-Compulsive DisorderPersonality AssessmentSex FactorsSomatoform DisordersTic DisordersConceptsImpulse control disordersInfluence of ageComorbidity patternsYale Global Tic Severity ScaleOCD patientsStructured Clinical InterviewTic Severity ScaleYale-Brown Obsessive Compulsive ScaleAttention-deficit/hyperactivity disorderObsessive Compulsive ScalePsychiatric comorbidityIllness durationTic disordersFemale genderSeverity ScaleClinical InterviewDSM-IVLower ageAnxiety disordersCompulsive ScaleHyperactivity disorderDisordersLower chanceAgeComorbiditiesPilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence
Morgan PT, Malison RT. Pilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence. The American Journal Of Drug And Alcohol Abuse 2008, 34: 692-702. PMID: 18850496, DOI: 10.1080/00952990802308221.Peer-Reviewed Original ResearchMeSH KeywordsAdultCocaine-Related DisordersCognition DisordersDisruptive, Impulse Control, and Conduct DisordersFemaleGABA AgonistsGABA ModulatorsHumansLearningLorazepamMaleMiddle AgedNipecotic AcidsPilot ProjectsPolysomnographySleep Initiation and Maintenance DisordersTiagabineConceptsSleep-dependent learningCocaine-dependent personsEffects of lorazepamCognitive effectsCognitive functionMotor learningTotal sleep timeDependent learningImpulsivitySlow-wave sleepCocaine abstinenceSleep latencyAbstinenceSleep timeSleepDependent personsLearningLight sleepCognitionCocaine administrationSedative hypnoticsPilot studyLorazepamParticipantsDifferent GABA
2007
Gender differences in the associations between past-year gambling problems and psychiatric disorders
Desai RA, Potenza MN. Gender differences in the associations between past-year gambling problems and psychiatric disorders. Social Psychiatry And Psychiatric Epidemiology 2007, 43: 173-183. PMID: 18080792, PMCID: PMC3700360, DOI: 10.1007/s00127-007-0283-z.Peer-Reviewed Original ResearchMeSH KeywordsAdultComorbidityDiagnostic and Statistical Manual of Mental DisordersDisruptive, Impulse Control, and Conduct DisordersFemaleGamblingHumansMaleMental DisordersPrevalenceSex FactorsConceptsPsychiatric disordersAxis II disordersNational Epidemiological SurveyBackgroundPsychiatric disordersMajor depressionNicotine dependenceAxis IEpidemiological surveyGender differencesSubsyndromal levelsPanic disorderPast-year gambling problemsRelated disordersTreatment effortsStrong associationDisordersWomenGambling problemsPathological gamblingMenAssociationDysthymiaAimToMethodsDataAlcoholism
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