2025
Gender Differences in Medicare Practice and Payment of Neuroradiologists.
Malhotra A, Lee C, Khunte M, Futela D, Moily R, Payabvash S, Gandhi D, Wintermark M. Gender Differences in Medicare Practice and Payment of Neuroradiologists. American Journal Of Neuroradiology 2025, 46: 1093-1099. PMID: 40461255, PMCID: PMC12152790, DOI: 10.3174/ajnr.a8633.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesFemaleHumansMaleMedicarePhysicians, WomenPractice Patterns, Physicians'RadiologistsRetrospective StudiesSex FactorsUnited StatesVariations in management strategies for stable coronary artery disease in the Asia-Pacific region: Insights from a multinational survey.
Cuenza L, Honda S, Fong K, Sawano M, Cader F, Surunchupakorn P, Widodo W, Dalakoti M, Kang J, Chimura M, Al-Omary M, Lee Z, Sari N, Suesat T, Ahmad T, Magno J, Tan C, Tiksnadi B, Hewarathna U, Habib F, Lee D, Yap J. Variations in management strategies for stable coronary artery disease in the Asia-Pacific region: Insights from a multinational survey. Annals, Academy Of Medicine, Singapore 2025, 54: 283-295. PMID: 40471110, DOI: 10.47102/annals-acadmedsg.2024340.Peer-Reviewed Original ResearchConceptsStable coronary artery diseaseCoronary artery diseaseRandomised controlled trialsPractice scoresGuideline recommendationsCross-sectional electronic surveyArtery diseaseManagement of stable coronary artery diseaseTreatment of stable coronary artery diseaseOptimal medical therapyKnowledge scoresLow attitude scoresAttitude scoresElectronic surveyMedical therapyBaseline knowledgeCase scenariosSociety guidelinesPractising physiciansContemporary guidelinesInvasive strategyControlled trialsCardiovascular physiciansGuideline interpretationCardiovascular practitionersHospital and Clinician Practice Variation in Cardiac Surgery and Postoperative Acute Kidney Injury
Mathis M, Mentz G, Cao J, Balczewski E, Janda A, Likosky D, Schonberger R, Hawkins R, Heung M, Ailawadi G, Ladhania R, Sjoding M, Kheterpal S, Singh K, Sundt T, Fitzsimons M, Shann K, Kumar V, Yarboro L, Naik B, Tibayan F, Aziz M, Mulligan M, Jelacic S, Kaneko T, Graetz T, Assi R, Mallidi H, Querejeta-Roca G, Shook D, Tsai C, Jewell E, Wanderer J, Freundlich R, Rock P, Douville N, Fisher C, Pace N, Domino K, Wagener G, King C, O'Reilly-Shah V, Bardia A, Clark D. Hospital and Clinician Practice Variation in Cardiac Surgery and Postoperative Acute Kidney Injury. JAMA Network Open 2025, 8: e258342. PMID: 40314957, PMCID: PMC12048843, DOI: 10.1001/jamanetworkopen.2025.8342.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedCardiac Surgical ProceduresCohort StudiesFemaleHospitalsHumansMaleMiddle AgedPostoperative ComplicationsPractice Patterns, Physicians'United StatesConceptsAcute kidney injuryClinician-level variationAssociated with acute kidney injuryAcute kidney injury ratesCardiac surgeryIntraclass correlation coefficientAdult patientsKidney injuryCohort studyCohort study of adult patientsResuscitation practicesPostoperative acute kidney injuryOperating room practiceStudy of adult patientsAssociated with increased morbidityCardiac surgical proceduresCardiac surgical databasePractice variationRBC transfusion ratesFluid volume administrationHospital-level variationMultilevel mixed-effects modelsPatient-level characteristicsRisk-adjustment modelsHealth care costsBrief verbal intervention to address inappropriate prescriptions of chinese patent medicines among western practitioners in primary health care (BRAVERY): a study protocol for an unannounced standardized patient experiment with a factorial design randomized controlled trial in China
Zhao Q, Lin L, Kwan A, Hu H, Wu L, Chen Y, Shi Z, Li B, Xiao J, Tong G, He W, Luo H, Li Q, Wang R, Zhong D, Liu S, Xie Y, Li J, Zhang L, Huang Z, Zhu X, Wan Y, Chen X, Huang W, Tian Y, Li X, Zhou Y, Cai Y, Xu D. Brief verbal intervention to address inappropriate prescriptions of chinese patent medicines among western practitioners in primary health care (BRAVERY): a study protocol for an unannounced standardized patient experiment with a factorial design randomized controlled trial in China. BMC Complementary Medicine And Therapies 2025, 25: 150. PMID: 40269893, PMCID: PMC12020188, DOI: 10.1186/s12906-025-04870-6.Peer-Reviewed Original ResearchMeSH KeywordsChinaDrugs, Chinese HerbalHumansInappropriate PrescribingMedicine, Chinese TraditionalNonprescription DrugsPractice Patterns, Physicians'Primary Health CareRandomized Controlled Trials as TopicConceptsUnannounced standardized patientsRandomized controlled trialsPrimary healthcareGeneralized linear mixed modelsWestern medicine practitionersPrimary health careControlled trialsFactorial design randomized controlled trialStudy protocolDesign randomized controlled trialChinese patent medicineVerbal interventionsChina Clinical Trial RegistryPatent medicineClinical Trials RegistryPrimary outcome evaluationStandardized patientsHealth careLinear mixed modelsMedical encountersControl providersTargeted policy interventionsIntervention researchPatient expectationsAppropriateness of antibiotic prescriptionsUse of broad-spectrum antibiotics in adult cancer patients presenting to emergency department with non-neutropenic fever and/or suspected infection
Li Y, Al Maqrashi Z, Zhan L, Siddiqui Z, Jin E, Ellis P. Use of broad-spectrum antibiotics in adult cancer patients presenting to emergency department with non-neutropenic fever and/or suspected infection. Supportive Care In Cancer 2025, 33: 383. PMID: 40237926, DOI: 10.1007/s00520-025-09419-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnti-Bacterial AgentsCohort StudiesEmergency Service, HospitalFemaleFeverHumansMaleMiddle AgedNeoplasmsPractice Patterns, Physicians'Retrospective StudiesConceptsNon-neutropenic feverBroad-spectrum antibioticsBroad-spectrum intravenous antibioticsBroad-spectrum antibiotic useCancer patientsSuspected infectionAdult cancer patientsAntibiotic useIntravenous antibioticsEmergency departmentAntibiotics prescribed to patientsMethodsA retrospective cohort studySingle-center studyProportion of patientsRetrospective cohort studyStage IV cancerMultivariate logistic regressionImprove antibiotic stewardshipSystemic treatmentSolid malignanciesGenitourinary cancersAdult patientsAntibiotic stewardshipIV cancerCohort studyAirway Safety During Mechanical Ventilation: Survey of ICU Clinicians Practices and Perceptions
Tanios M, Stocking J, Charchaflieh J, Miller A, Patel J, Vilella A, Nguyen H, Epstein S, Beltran A, Devlin J. Airway Safety During Mechanical Ventilation: Survey of ICU Clinicians Practices and Perceptions. Critical Care Explorations 2025, 7: e1234. PMID: 40126919, PMCID: PMC11936560, DOI: 10.1097/cce.0000000000001234.Peer-Reviewed Original ResearchConceptsUnplanned extubationAdult ICUsSociety of Critical Care MedicineEvidence-based guidelinesCritical care medicineAirway management practicesPressure injuriesSurvey of membersClinician practiceManagement beliefsSafety practicesCare medicineICU settingRisk factorsManagement practicesPediatric ICUResponsibility assignmentICUSurveyRespondentsPracticeColorectal surgeon practice patterns of low anterior resection syndrome after rectal cancer treatment
Coppersmith N, Schultz K, Esposito A, Cruickshank K, Saleh A, Linhares S, Leeds I, Pantel H, Reddy V, Longo W, Mongiu A. Colorectal surgeon practice patterns of low anterior resection syndrome after rectal cancer treatment. Supportive Care In Cancer 2025, 33: 218. PMID: 39994079, DOI: 10.1007/s00520-025-09290-3.Peer-Reviewed Original ResearchConceptsLow anterior resection syndromeRisk of low anterior resection syndromeAnterior resection syndromeManagement of low anterior resection syndromeDescriptive statistical analysisPhysical therapyIncreased screeningRectal cancer treatmentSurgery facultyRectal surgery residentsPatient accessElectronic surveyResultsThe surveyLifestyle modificationPractice patternsLogistic regressionCounseling patientsRectal resectionTreatment modalitiesPostoperative screeningPostoperative patientsTransanal irrigationTreatment practicesSurgeons' perceptionsDrug treatmentInternational perspectives on physician knowledge, attitudes, and practices related to medical cannabis
Syed S, Singh J, Elkholy H, Palavra I, Tomicevic M, Eric A, da Costa M, Guloksuz S, Radhakrishnan R. International perspectives on physician knowledge, attitudes, and practices related to medical cannabis. Frontiers In Public Health 2025, 13: 1463871. PMID: 40051509, PMCID: PMC11882600, DOI: 10.3389/fpubh.2025.1463871.Peer-Reviewed Original ResearchConceptsPhysicians' knowledgeStrength of evidenceMedical cannabisCross-sectional survey of physiciansSurvey of physiciansCross-sectional surveyYears of clinical experienceNegative health outcomesCannabis useClinical experienceRefractory chronic neuropathic painClinical decision-makingHealth outcomesPhysicians' attitudesPhysicians' willingnessChronic neuropathic painMedical use of cannabisRisk of psychosisDaily cannabis useMedication useDescriptive statisticsRisk of addictionMedical indicationsUse of cannabisPhysiciansAdaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Optimization Strategy trial
Iscoe M, Hooper C, Levy D, Buchanan L, Dziura J, Meeker D, Taylor R, D’Onofrio G, Oladele C, Sarpong D, Paek H, Wilson F, Heagerty P, Delgado M, Hoppe J, Melnick E. Adaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Optimization Strategy trial. BMJ Open 2025, 15: e098072. PMID: 39979056, PMCID: PMC11842997, DOI: 10.1136/bmjopen-2024-098072.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidBuprenorphineDecision Support Systems, ClinicalEmergency Service, HospitalHumansNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersPractice Patterns, Physicians'ConceptsClinical decision supportMultiphase optimization strategyOpioid use disorderEmergency departmentInitiation of buprenorphineClinical decision support usePlan-Do-Study-Act cyclesLearning health system approachPlan-Do-Study-ActClinical decision support toolHealth system approachAdaptive decision supportUse disorderDecision supportAddiction treatmentPeer-reviewed journalsBuprenorphine initiationOpioid use disorder treatment initiationOpioid-related mortalityIntervention componentsED settingClinician feedbackInstitute Institutional Review BoardTreatment of opioid use disorderParticipating sitesDiagnosis, screening, and follow-up of patients with familial interstitial lung disease: Results from an international survey
Moen E, Prior T, Kreuter M, Wuyts W, Molina-Molina M, Wijsenbeek M, Morais A, Tzouvelekis A, Ryerson C, Caro F, Buendia-Roldan I, Magnusson J, Lee J, Morisett J, Oldham J, Troy L, Funke-Chambour M, Alberti M, Borie R, Walsh S, Rajan S, Kondoh Y, Khor Y, Bendstrup E. Diagnosis, screening, and follow-up of patients with familial interstitial lung disease: Results from an international survey. BMC Pulmonary Medicine 2025, 25: 59. PMID: 39901224, PMCID: PMC11792556, DOI: 10.1186/s12890-025-03532-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleGenetic TestingHumansLung Diseases, InterstitialLung TransplantationMaleMiddle AgedPractice Patterns, Physicians'PulmonologistsSurveys and QuestionnairesConceptsGenetic testing methodsMultidisciplinary teamGenetic testingFamily historyInterstitial lung diseaseHistory of interstitial lung diseaseRecommended genetic testingScreening of first-degree relativesFamilial interstitial lung diseaseEvidence-based guidelinesGenetic screening of relativesScreening of relativesFirst-degree relativesCharacteristics of respondentsInternational surveyPathogenic genetic variantsScreening toolLung transplantationInsufficient evidenceLung diseaseConsensus statementGenetic variantsFollow-up of patientsStandard programRespondentsPreferences for Inguinal Hernia Repair in Infants: A Survey of the Eastern Pediatric Surgery Network
Hellmann Z, Knod J, Kulaylat A, Griggs C, DeFazio J, Scholz S, Alemayehu H, Robinson J, Kunisaki S, Hornick M, Collaborators E, Allukian M, Chandler N, Feng C, Finck C, Gander J, Lipskar A, McLean S, Middlesworth W, Nandivada P, Rangel S, Robertson J, Russell R, Slidell M, Taylor J, Tracy E. Preferences for Inguinal Hernia Repair in Infants: A Survey of the Eastern Pediatric Surgery Network. Journal Of Surgical Research 2025, 306: 188-196. PMID: 39793305, DOI: 10.1016/j.jss.2024.12.012.Peer-Reviewed Original ResearchMeSH KeywordsFemaleHernia, InguinalHerniorrhaphyHumansInfantLaparoscopyMalePediatricsPractice Patterns, Physicians'SurgeonsSurveys and QuestionnairesConceptsLaparoscopic inguinal hernia repairInguinal hernia repairPediatric surgeonsHernia repairCompare long-term outcomesStandard open techniqueLong-term outcomesLate-career surgeonsSurgical practice patternsEarly-career surgeonsMid-career surgeonsSurveyed pediatric surgeonsChi-square testLaparoscopic approachOpen techniqueSurgeon preferenceContralateral sidePatient populationInfantsPractice patternsTechnical easeSurgeonsT-testRepairHerniaPatterns of adjuvant bone modifying agent use in patients with early-stage breast cancer in the United States
Odzer N, Chehayeb R, Schellhorn S, Lustberg M, Gross C, Lee D, Foldi J. Patterns of adjuvant bone modifying agent use in patients with early-stage breast cancer in the United States. Breast Cancer Research 2025, 27: 102. PMID: 40500761, PMCID: PMC12160112, DOI: 10.1186/s13058-025-02062-1.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerBone-modifying agentsBreast cancerAssociated with increased receiptHealth care practicesFactors associated with receiptPost-menopausal statusInconsistent prescribingCare practicesRetrospective cohort studyElectronic health record-derived databaseReceipt of adjuvant chemotherapyEstrogen receptor (ER)-positiveSurvey-based studyYears of ageClinical guidelinesCohort studyUnited StatesProportion of patientsChi-squareAdjuvant bisphosphonatesResultsOur cohortNode-negativeEndocrine therapyPrescribing
2024
Patient Characteristics and Practice Variation Associated With New Community Prescription of Benzodiazepine and z‐Drug Hypnotics After Critical Illness: A Retrospective Cohort Study Using the UK Clinical Practice Research Datalink
Mansi E, Rentsch C, Bourne R, Guthrie B, Lone N. Patient Characteristics and Practice Variation Associated With New Community Prescription of Benzodiazepine and z‐Drug Hypnotics After Critical Illness: A Retrospective Cohort Study Using the UK Clinical Practice Research Datalink. Pharmacoepidemiology And Drug Safety 2024, 33: e70056. PMID: 39603606, PMCID: PMC11602247, DOI: 10.1002/pds.70056.Peer-Reviewed Original ResearchConceptsCommunity prescriptionsZ-drugsIllness survivorsRetrospective cohort studyClinical Practice Research Datalink dataPractice variationUK Clinical Practice Research DatalinkClinical Practice Research DatalinkWorsening mental health conditionsCohort studyMultilevel multivariable logistic regressionSurvivors of critical illnessZ-drug prescribingCritical care survivorsPrimary care practicesCritical illnessMental health conditionsZ-drug prescriptionsCritical illness survivorsMultivariate logistic regressionPrescription opioid useCare practicesRisk of adverse eventsHealth conditionsHistory of insomniaWhen Benchmarks Fail Us: A Case Study in Cytoreductive Surgery
Bansal V, Witmer H, Childers C, Su D, Turaga K. When Benchmarks Fail Us: A Case Study in Cytoreductive Surgery. Annals Of Surgical Oncology 2024, 32: 19-23. PMID: 39460818, DOI: 10.1245/s10434-024-16191-y.Peer-Reviewed Original ResearchMeSH KeywordsBenchmarkingClinical CodingCytoreduction Surgical ProceduresHumansPeritoneal NeoplasmsPractice Patterns, Physicians'PrognosisRelative Value ScalesSurgeonsSurveys and QuestionnairesStrategies to Deimplement Opioid Prescribing in Primary Care
Quanbeck A, Robinson J, Jacobson N, Li X, Hennessy-Garza R, Landeck J, Cohen A, Madden L, Pulvermacher A, Brown R. Strategies to Deimplement Opioid Prescribing in Primary Care. JAMA Network Open 2024, 7: e2438325. PMID: 39388183, PMCID: PMC11581553, DOI: 10.1001/jamanetworkopen.2024.38325.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalgesics, OpioidChronic PainFemaleGuideline AdherenceHumansMaleMiddle AgedPractice Patterns, Physicians'Primary Health CareUnited StatesConceptsCluster randomized clinical trialDeimplementation strategiesMorphine milligram equivalent doseMorphine milligram equivalentsPractice facilitationOpioid prescribingIncreased screeningTreatment agreementsUS health care systemCenters for Disease Control and Prevention guidelinesRandomized clinical trialsUrine drug screensPrimary care clinicsPrimary care settingPrimary outcomeMental health screeningPain-related interferenceHealth care systemHigh-intensity groupEnjoyment of lifeChronic pain managementPrimary careCare clinicsCare settingsHealth screeningPeri-Arthroscopic Management of Immunosuppressive Medications in Patients with Rheumatic Disease A Survey of Practice Trends Among Rheumatologists and Sports Medicine Orthopedic Surgeons.
Vasavada K, Jazrawi L, Samuels J. Peri-Arthroscopic Management of Immunosuppressive Medications in Patients with Rheumatic Disease A Survey of Practice Trends Among Rheumatologists and Sports Medicine Orthopedic Surgeons. Bulletin Of The NYU Hospital For Joint Disease 2024, 82: 186-193. PMID: 39150872.Peer-Reviewed Original ResearchConceptsJanus kinase inhibitorsRheumatic disease patientsHigh-risk surgeryAnterior cruciate ligamentRisk surgeryOrthopedic surgeonsDisease patientsRisk of disease flarePreferred patientsRisk of postoperative infectionJanus kinaseDose of rituximabUse of immunosuppressantsManagement of immunosuppressionFellowship-trained orthopedic surgeonsManagement of immunosuppressive medicationsSynthetic diseasemodifying antirheumatic drugsSports medicine surgeonsSports medicine orthopedic surgeonsAnti-rheumatic medicationsEvidence-based guidelinesImmunosuppressive medicationsPostoperative infectionDisease flareAntirheumatic drugsPrescription Patterns for Sodium-Glucose Cotransporter 2 Inhibitors in U.S. Health Systems
Shin J, Xu Y, Chang A, Carrero J, Flaherty C, Mukhopadhyay A, Inker L, Blecker S, Horwitz L, Grams M. Prescription Patterns for Sodium-Glucose Cotransporter 2 Inhibitors in U.S. Health Systems. Journal Of The American College Of Cardiology 2024, 84: 683-693. PMID: 39142721, PMCID: PMC11789666, DOI: 10.1016/j.jacc.2024.05.057.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDiabetes Mellitus, Type 2Drug PrescriptionsFemaleHumansMaleMiddle AgedPractice Patterns, Physicians'Sodium-Glucose Transporter 2 InhibitorsUnited StatesConceptsSodium-glucose cotransporter 2Class 1A recommendationSodium-glucose cotransporter 2 inhibitor therapyChronic kidney diseaseU.S. health systemHealth systemInhibitor prescriptionHeart failurePrescription ratesInhibitor therapyInhibitor useSodium-glucose cotransporter 2 inhibitorsSodium-glucose cotransporter 2 inhibitor useOptum Labs Data WarehouseProportion of patientsSGLT2 inhibitor usePresence of diabetesRecurrent cardiovascular eventsAtherosclerotic cardiovascular diseaseCotransporter 2Analysis of U.S. dataSevere albuminuriaPrescription patternsCardiovascular eventsCommercial insuranceHigh rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine
Ottesen T, Wickersham J, Lawrence J, Antoniak S, Zezuilin O, Polonsky M, Antonyak S, Rozanova J, Dvoriak S, Pykalo I, Filippovych M, Altice F. High rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine. PLOS ONE 2024, 19: e0305086. PMID: 39028735, PMCID: PMC11259278, DOI: 10.1371/journal.pone.0305086.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsCD4 Lymphocyte CountFemaleHIV InfectionsHumansMaleMiddle AgedPhysiciansPractice Patterns, Physicians'Social StigmaSubstance-Related DisordersSurveys and QuestionnairesUkraineConceptsAntiretroviral therapy prescriptionAntiretroviral therapyCD4 countSubstance use disordersIncreased levels of stigmaNational sampleLevel of stigmaIndependent of risk groupSuboptimal antiretroviral therapyInitiate antiretroviral therapyPopulation of peopleHIV expertsHIV incidenceHIV physiciansHIV treatmentKey populationsTransgender womenAntiretroviral treatmentFeeling thermometerDrinking alcoholSex workersPhysiciansSex partnersPWHRisk groupsUse of Muscle Relaxants After Surgery in Traditional Medicare Part D Enrollees
Bongiovanni T, Gan S, Finlayson E, Ross J, Harrison J, Boscardin J, Steinman M. Use of Muscle Relaxants After Surgery in Traditional Medicare Part D Enrollees. Drugs & Aging 2024, 41: 615-622. PMID: 38980644, PMCID: PMC11249446, DOI: 10.1007/s40266-024-01124-x.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overDrug PrescriptionsFemaleHumansMaleMedicare Part DPain, PostoperativePractice Patterns, Physicians'Retrospective StudiesUnited StatesConceptsMuscle relaxant prescriptionsOlder adultsSpine proceduresPain controlMuscle relaxationRisk of prolonged useProlonged useMedication-related problemsDecreased opioid useRates of prescribingMuscle relaxant useResultsThe study cohortPostoperative pain managementPrescribed to patientsYears of agePostoperative prescribingStudy DesignUsingNonopioid medicationsOpioid useOpioid prescribingMedicare Part DPostoperative periodMedicare Part D enrolleesRetrospective analysisPain managementHow Should the Use of Opioids Be Regulated to Motivate Better Clinical Practice?
Edens E, Garcia Vassallo G, Heimer R. How Should the Use of Opioids Be Regulated to Motivate Better Clinical Practice? The AMA Journal Of Ethic 2024, 26: e551-561. PMID: 38958424, DOI: 10.1001/amajethics.2024.551.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidDrug and Narcotic ControlDrug PrescriptionsHumansMotivationOpioid-Related DisordersPainPractice Patterns, Physicians'United StatesConceptsTreat opioid use disorderOpioid use disorderPrescribed long-term opioid therapyLong-term opioid therapyOpioid prescribing policiesOpioid therapyPrescribed opioidsOpioid prescribingUse disorderOpioidClinical practicePainPrescribing policiesDiagnostic categoriesClinical frameworkPrescribingPolitical reasonsTherapy
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