2025
The Impact and Safety of GLP‐1 Agents and Breast Cancer
Parsons K, Montalvo M, Fischbach N, Taylor M, Alfaro S, Lustberg M. The Impact and Safety of GLP‐1 Agents and Breast Cancer. Cancer Medicine 2025, 14: e70932. PMID: 40552446, PMCID: PMC12186097, DOI: 10.1002/cam4.70932.Peer-Reviewed Original ResearchConceptsBreast cancer patientsGLP-1 receptor agonistsBreast cancerBreast cancer-specific mortalityCancer patientsBreast cancer incidenceBreast cancer ratesWeight management interventionsProportion of breast cancer patientsNon-cancer populationObese post-menopausal womenReceptor agonistsBreast cancer outcomesBreast cancer progressionWeight loss interventionWeight management strategiesEffective weight managementGLP-1Quality of lifeAll-cause mortalityCancer-specific mortalityImprove patient outcomesObesity prevalenceWeb of ScienceCancer incidenceRevitalizing reproductive health: innovations and future frontiers in restorative medicine
Bulletti F, Giacomucci E, Guido M, Palagiano A, Coccia M, Bulletti C. Revitalizing reproductive health: innovations and future frontiers in restorative medicine. Therapeutic Advances In Reproductive Health 2025, 19: 26334941251345844. PMID: 40546415, PMCID: PMC12182620, DOI: 10.1177/26334941251345844.Peer-Reviewed Original ResearchFertility careThyroid dysfunctionReproductive medicineFactors affecting infertilityLive birth rateMedically assisted reproductionNewcastle-Ottawa ScaleCochrane risk of bias toolAssisted reproductive technologyRisk of bias toolMulticenter trialPublic health challengeSurgical correctionReproductive-aged individualsEmbryo transferFertility outcomesART successSystem abnormalitiesBirth ratePregnancy rateAssisted reproductionNewcastle-OttawaWeb of ScienceReproductive technologyInclusion criteriaOsseous Genioplasty and its Impact on Airway Volume – What is the Evidence?
Kauke-Navarro M, Knoedler L, Stucki L, Klimitz F, Allam O, Knoedler S, Navarro M, Flores-Pérez P, Rancu A, Heiland M, Alperovich M, Safi A. Osseous Genioplasty and its Impact on Airway Volume – What is the Evidence? Aesthetic Surgery Journal Open Forum 2025, ojaf059. DOI: 10.1093/asjof/ojaf059.Peer-Reviewed Original ResearchObstructive sleep apneaChin advancementOsseous genioplastyAirway volumeAirway changesObstructive sleep apnea metricsObstructive sleep apnea symptomsEvaluate long-term resultsAbsolute volume increasePosterior airway spaceApnea-hypopnea indexLong-term resultsAirway enlargementHyoid advancementAirway spaceSleep apneaSnoring severityFacial aestheticsSurgical techniqueAirway dimensionsAirway sizeGenioplastyWeb of ScienceAssociated soft tissuesAirwayDigital Health Interventions Targeting Psychological Health in Parents of Children With Autism Spectrum Disorder: Protocol for a Scoping Review
Ji B, Batubara I, Batten J, Peng X, Chen S, Ni Z. Digital Health Interventions Targeting Psychological Health in Parents of Children With Autism Spectrum Disorder: Protocol for a Scoping Review. JMIR Research Protocols 2025, 14: e68677. PMID: 40466097, PMCID: PMC12177426, DOI: 10.2196/68677.Peer-Reviewed Original ResearchConceptsDigital health interventionsParents of childrenINTERNATIONAL REGISTERED REPORT IDENTIFIERParental psychological healthPsychological healthScoping reviewAutism spectrum disorderDevelopment of practice guidelinesPsychological health outcomesHealth of parentsEnglish-language studiesPsychological health of parentsWeb of SciencePublic health concernHealth outcomesHealth interventionsSpectrum disorderEvidence synthesisParticipant characteristicsIntervention specificsPsychological outcomesPractice guidelinesStudy designData extractionOvid MEDLINEImpact of age on financial toxicity among breast cancer patients with resectable invasive breast cancer: A systematic review.
Myers S, Morton C, Bain P, Obeng-Gyasi S, Paskett E, McAlearney A, Greenup R, Minami C, Mittendorf E, King T. Impact of age on financial toxicity among breast cancer patients with resectable invasive breast cancer: A systematic review. Journal Of Clinical Oncology 2025, 43 DOI: 10.1200/jco.2025.43.16_suppl.e23194.Peer-Reviewed Original ResearchCancer-related costsFinancial toxicitySystematic reviewInvasive breast cancerSocial determinants of healthBreast cancerSymptoms of breast cancerBlood Institute assessment toolIncidence of breast cancerOutcome metricsPatient-reported outcome metricsStage I-III breast cancerDeterminants of healthI-III breast cancerNon-metastatic invasive breast cancerAffordability of careBreast cancer diagnosisYounger ageYoung adultsInstitute assessment toolEnglish-language articlesHealth disparitiesSocial determinantsTreatment-related expensesWeb of SciencePrevalence of common mental disorders and sleep disorder among adolescents and young adults with HIV: a systematic review and meta-analysis
Tan Y, Ma Z, Cao Q, Gao S, Xiong Y. Prevalence of common mental disorders and sleep disorder among adolescents and young adults with HIV: a systematic review and meta-analysis. BMJ Open 2025, 15: e093320. PMID: 40379341, PMCID: PMC12083388, DOI: 10.1136/bmjopen-2024-093320.Peer-Reviewed Original ResearchConceptsPrevalence of depressionPrevalence of sleep disordersPooled prevalenceSleep disordersRisk of depressionPost-traumatic stress disorderSubgroup analysisHIV-uninfected peersSensitive screening strategyPublication biasPooled prevalence of depressionCertainty of evidenceYoung adultsCase reportEvaluate study qualityPooled prevalence of anxietyFixed-effects modelPrevalence of anxietySources of heterogeneityWeb of ScienceHIVObservational studyPooled estimatesPrevalence of post-traumatic stress disorderRecommendations AssessmentAccuracy of Home Blood Pressure Monitoring in Youth: A Systematic Review and Meta-Analysis
Cueto V, Medvecky H, Funaro M, Nugent J. Accuracy of Home Blood Pressure Monitoring in Youth: A Systematic Review and Meta-Analysis. The Journal Of Pediatrics 2025, 284: 114633. PMID: 40334740, DOI: 10.1016/j.jpeds.2025.114633.Peer-Reviewed Original ResearchAmbulatory BP monitoringHome blood pressure monitoringBlood pressure monitoringHome BPAmbulatory BPPressure monitoringAwake ambulatory BPMeta-analysisModerate agreementWhite coat hypertensionRandom-effects weightingAsleep ambulatory BPDaytime ambulatory hypertensionAmbulatory hypertensionWeb of ScienceBP monitoringCochrane LibraryHypertensionHBPM protocolClinical practiceNocturnal home BPAssess outcomesSystematic reviewHypertension thresholdCategorical scaleSafety of Stimulants Across Patient Populations
Oliva H, Prudente T, Mayerson T, Mignosa M, Oliva I, Potenza M, Jegede O, Angarita G. Safety of Stimulants Across Patient Populations. JAMA Network Open 2025, 8: e259492. PMID: 40343695, PMCID: PMC12065045, DOI: 10.1001/jamanetworkopen.2025.9492.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderRandomized clinical trialsAdverse eventsStimulant medicationData extractionSafety of stimulationRisk ratioIncreased riskMethodological quality assessmentPreferred Reporting ItemsPatient populationClinical conditionsDiverse patient populationsRisk of biasSafety of stimulant medicationsUnclear risk of biasTreatment of attention-deficit/hyperactivity disorderOverall AEsRandom-effects modelWeb of ScienceBinge eating disorderStimulant use disorderComprehensive literature searchMain OutcomesReporting ItemsEfficacy of enhanced recovery programmes for cardiac surgery: a systematic review and meta-analysis
Hoogma D, Meeusen I, Coppens S, Verbrugghe P, van den Eynde J, Engelman D, Grant M, Stoppe C, Rex S. Efficacy of enhanced recovery programmes for cardiac surgery: a systematic review and meta-analysis. British Journal Of Anaesthesia 2025, 135: 31-39. PMID: 40287362, DOI: 10.1016/j.bja.2025.03.019.Peer-Reviewed Original ResearchConceptsHospital length of stayLength of stayCardiac surgeryFast-track cardiac anesthesiaFast-track (FTICU length of stayMeta-analysisAssessed risk of biasRandom-effects modelAdditive valueRisk of biasPerioperative strategiesEfficacy outcomesVentilation timeFT programmesVentilatory timeHospital lengthPostoperative interventionsCardiac anesthesiaComparative efficacySurgeryWeb of ScienceRandomised trialsPRISMA guidelinesEnhanced recoverySinonasal Presentations of Immunoglobulin G4‐Related Disease: A Scoping Review
Farrokh F, Rimmer R. Sinonasal Presentations of Immunoglobulin G4‐Related Disease: A Scoping Review. The Laryngoscope 2025 PMID: 40231759, DOI: 10.1002/lary.32196.Peer-Reviewed Original ResearchSinonasal regionSinonasal manifestationsOrgan systemsImmunoglobulin G4-related diseaseFrequent site of involvementSite of involvementClassification criteriaSinonasal presentationSinonasal involvementMaxillary sinusEthmoid sinusIgG4RDFrequent siteClinical symptomsNasal cavityRayyan platformWeb of ScienceImmune diseasesLiterature searchSimultaneous involvementSinusPatientsJBI guidelinesDiagnosisInvolvementCraniosynostosis among children with X-linked hypophosphatemia: A systematic review and meta-analysis
Fisch S, Tudor A, Benchekroun E, Landsberg W, Feldstein N, Lamb M, Carpenter T, Rundle A, Jacobson J, Neugut A, Freedberg D. Craniosynostosis among children with X-linked hypophosphatemia: A systematic review and meta-analysis. Bone 2025, 196: 117488. PMID: 40220947, DOI: 10.1016/j.bone.2025.117488.Peer-Reviewed Original ResearchX-linked hypophosphatemiaPrevalence of craniosynostosisPooled prevalenceSystematic reviewMeta-analysisRandom-effects modelWeb of SciencePediatric populationSkull abnormalitiesCohort studyImpaired phosphate reabsorptionElevated FGF23 levelsPrevalenceFemale predominanceCase seriesFGF23 levelsPhosphate reabsorptionGene variantsChildrenIncreased vigilanceCraniosynostosisAbnormal bone growthGenetic disordersHypophosphatemiaAbnormalitiesSocial Determinants of Health and Suicide-Related Outcomes
Na P, Shin J, Kwak H, Lee J, Jester D, Bandara P, Kim J, Moutier C, Pietrzak R, Oquendo M, Jeste D. Social Determinants of Health and Suicide-Related Outcomes. JAMA Psychiatry 2025, 82: 337-346. PMID: 39745761, PMCID: PMC11964833, DOI: 10.1001/jamapsychiatry.2024.4241.Peer-Reviewed Original ResearchSocial determinants of healthSuicide mortalitySuicide-related outcomesAssociation of social determinants of healthRisk of suicide mortalityPrevent suicideAssociated with suicide mortalitySuicidal ideationHomeless individualsMeta-analysesDeterminants of healthSuicide riskRisk factorsPublic health policiesSuicide attemptsIncarcerated female youthIntimate partner violenceSexual minority statusPrevalence of lifetime suicidal ideationIncreased suicide riskExperiences of childhood abuseSocial determinantsWeb of ScienceResearch SynthesesTailored interventionsA systematic review of implant materials for facial reconstructive and aesthetic surgery
Kauke-Navarro M, Knoedler L, Baecher H, Sherwani K, Knoedler S, Allam O, Diatta F, Alperovich M, Safi A. A systematic review of implant materials for facial reconstructive and aesthetic surgery. Frontiers In Surgery 2025, 12: 1548597. PMID: 40225117, PMCID: PMC11985522, DOI: 10.3389/fsurg.2025.1548597.Peer-Reviewed Original ResearchPatient-specific implantsFacial implantsBone resorption ratePlastic surgery techniquesStandardized outcome reportingSystematic reviewPatient ageImplant displacementNerve injurySafety profileSurgery techniquesPostoperative recoveryFollow-upAlloplastic materialsReduce complicationsPotential complicationsWeb of SciencePatient anatomyInclusion criteriaResorption rateLong-term effectsAesthetic surgeryClinical practicePRISMA guidelinesOutcome reportingAssociation between loneliness and suicidality among general populations and persons with depressive and bipolar disorders: A systematic review
Lu A, Chan A, Menon T, Le G, Wong S, Ho R, Lo H, Rhee T, Lim P, Guillen-Burgos H, McIntyre R. Association between loneliness and suicidality among general populations and persons with depressive and bipolar disorders: A systematic review. Journal Of Affective Disorders 2025, 380: 777-801. PMID: 40157511, DOI: 10.1016/j.jad.2025.03.150.Peer-Reviewed Original ResearchConceptsGeneral population sampleBipolar disorderSystematic reviewPopulation sampleAge groupsHealthy adultsWeb of ScienceOlder adultsUnadjusted modelsDepressive symptomsData extractionDepressive disorderEligibility criteriaModerate positive correlationNIH toolPositive associationLonelinessEvaluate personalitySuicideAdultsClinical diagnosisDisordersQuality assessmentAssociationComprehensive assessmentThe association between internet-use-disorder symptoms and loneliness: a systematic review and meta-analysis with a categorical approach
Mestre-Bach G, Paiva U, San Martín Iniguez L, Beranuy M, Martín-Vivar M, Mallorquí-Bagué N, Normand E, Chicote M, Potenza M, Arrondo G. The association between internet-use-disorder symptoms and loneliness: a systematic review and meta-analysis with a categorical approach. Psychological Medicine 2025, 55: e77. PMID: 40071718, PMCID: PMC12080635, DOI: 10.1017/s0033291725000376.Peer-Reviewed Original ResearchConceptsInternet-use disordersSystematic reviewMeta-analysisInternet-useInternet use disorderRandom-effects modelWeb of ScienceDegree of lonelinessUCLA Loneliness ScaleStatistical poolingQuantify associationsOdds ratioCohen's dDisorder symptomsGreater lonelinessMeta-regressionPooled differenceEffect sizePre-registeredUCLA-LonelinessLonelinessEffects of ageCategorical approachSymptomsGroup of individualsUnderstanding oncologic emergencies and related emergency department visits and hospitalizations: a systematic review
Yilmaz S, Aryal K, King J, Bischof J, Hong A, Wood N, Gould Rothberg B, Hudson M, Heinert S, Wattana M, Coyne C, Reyes-Gibby C, Todd K, Lyman G, Klotz A, Abar B, Grudzen C, Bastani A, Baugh C, Henning D, Bernstein S, Rico J, Ryan R, Yeung S, Qdaisat A, Padela A, Madsen T, Liu R, Adler D. Understanding oncologic emergencies and related emergency department visits and hospitalizations: a systematic review. BMC Emergency Medicine 2025, 25: 40. PMID: 40045233, PMCID: PMC11883922, DOI: 10.1186/s12873-025-01183-2.Peer-Reviewed Original ResearchConceptsEmergency departmentEmergency visitsPredictors of ED usePeer-reviewed original research studiesSystematic reviewOncologic emergencyCancer incidence ratesCare delivery pathwaysGeriatric oncology researchManagement of oncologic emergenciesEmergency department visitsResultsThe search strategyTreatment side effectsOriginal research studiesCancer patientsVulnerable patient populationAcute careSingle-site studyWeb of ScienceCare venuesED useDepartment visitsHealth systemED visitsED presentationsExamining the Impact of the Syndemic on Black Birthing Individuals in the USA: a Systematic Review
Wisniewski K, Henry N, Flanagan A, Popoola A, Weaver N, Iglio L, Alexandre C, Myers D, Tieu T, Waller R, Kornfield S, Gur R, Momplaisir F, Njoroge W. Examining the Impact of the Syndemic on Black Birthing Individuals in the USA: a Systematic Review. Journal Of Racial And Ethnic Health Disparities 2025, 1-15. PMID: 39994154, DOI: 10.1007/s40615-025-02311-1.Peer-Reviewed Original ResearchBirthing individualsSystematic reviewMaternal health disparitiesWork-related challengesHealthcare discriminationPeer-reviewed articlesHealth disparitiesPostpartum experiencesSystemic racismWeb of ScienceInclusion criteriaAbstracted dataPRISMA guidelinesWell-beingMinoritized populationsScreening studiesPeer reviewFamily relationshipsCOVID-19COVID-19 pandemicSyndemicsThemesPublished literatureIndividual experienceCoronavirus disease 2019Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis
Sumsuzzman D, Ye Y, Wang Z, Pandey A, Langley J, Galvani A, Moghadas S. Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis. BMC Infectious Diseases 2025, 25: 215. PMID: 39948450, PMCID: PMC11827239, DOI: 10.1186/s12879-025-10610-5.Peer-Reviewed Original ResearchConceptsPopulation settingEffective public health strategiesConfidence intervalsImpact of disease severityModified Newcastle-Ottawa ScalePublic health strategiesHigher secondary attack rateRisk of biasNewcastle-Ottawa ScalePandemic responseGlobal systematic reviewRandom-effects modelFreeman-Tukey double arcsine transformationWeb of ScienceNo significant associationDrivers of SARS-CoV-2 transmissionHealth strategiesSecondary attack rateSARS-CoV-2Disease severityEffective pandemic responseTargeted interventionsDouble arcsine transformationOvid MEDLINESystematic reviewA systematic review on the assessment of pregnancy-specific psychological trauma during pregnancy: A call to action
Givrad S, Wall K, Goldman L, Shin J, Novak E, Lowell A, Penner F, Day M, Papa L, Wright D, Rutherford H. A systematic review on the assessment of pregnancy-specific psychological trauma during pregnancy: A call to action. AJOG Global Reports 2025, 5: 100451. PMID: 40093874, PMCID: PMC11909425, DOI: 10.1016/j.xagr.2025.100451.Peer-Reviewed Original ResearchSystematic reviewPerinatal periodPsychological traumaPreferred Reporting ItemsCare deliveryWeb of ScienceReporting ItemsHealthcare systemIndependent reviewersInfant healthSecondary analysisScreening measuresOvid MEDLINEFull-textOvid EmbaseHistory of traumatic experiencesResearch teamPsychological disordersPerinatal individualsOvidPregnancyTraumatic experiencesTeamTraumaPsycINFOEffects of psychedelics on opioid use disorder: a scoping review of preclinical studies
Pulido-Saavedra A, Oliva H, Prudente T, Kitaneh R, Nunes E, Fogg C, Funaro M, Weleff J, Nia A, Angarita G. Effects of psychedelics on opioid use disorder: a scoping review of preclinical studies. Cellular And Molecular Life Sciences 2025, 82: 49. PMID: 39833376, PMCID: PMC11747050, DOI: 10.1007/s00018-024-05519-2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid use disorderUse disorderPreclinical studiesClinical studiesReview of preclinical studiesConditioned place preferenceOpioid self-administrationEffects of psychedelicsPreclinical in vivo studiesOpioid use disorder treatmentFrequency of administrationPlace preferencePotential therapeutic effectsSelf-administrationWithdrawal symptomsPreclinical findingsMechanism of actionSafety profilePain studiesPsychedelicsMethodological quality assessmentClinical evidenceCardiovascular riskOpioidWeb of Science
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