2025
Cognitive-behavioral interventions for co-occurring substance use and mental health disorders
Magill M, Helminen E, Lynch-Gadaleta B, Allen K, Kiluk B, Ray L. Cognitive-behavioral interventions for co-occurring substance use and mental health disorders. Drug And Alcohol Dependence 2025, 274: 112756. PMID: 40543363, DOI: 10.1016/j.drugalcdep.2025.112756.Peer-Reviewed Original ResearchMental health disordersUsual careCo-occurring mental health conditionsHealth disordersCo-occurring substance useCognitive-behavioral interventionsPattern of effectsCompared to usual careMental health conditionsSubstance useSample of studyMental healthPsychosocial outcomesDrug useDisordersHealth conditionsDiagnostic criteriaOutcome typesStudy samplePublished outcome dataCareControl comparatorMeta-analysisLiterature searchOutcome dataInformation Needs for Opioid Use Disorder Treatment Using Buprenorphine Product: Qualitative Analysis of Suboxone-Focused Reddit Data
Basak M, Sharif O, Lord S, Borodovsky J, Marsch L, Springer S, Nunes E, Brackett C, Archibald L, Preum S. Information Needs for Opioid Use Disorder Treatment Using Buprenorphine Product: Qualitative Analysis of Suboxone-Focused Reddit Data. Journal Of Medical Internet Research 2025, 27: e68886. PMID: 40489766, PMCID: PMC12186000, DOI: 10.2196/68886.Peer-Reviewed Original ResearchConceptsLarge-scale dataPotential rumorsSocial media platformsReddit postsInformation needsOpioid use disorder treatmentOpioid use disorderMedia platformsUse disorderDisorder treatmentRedditSocial mediaHypothesis generationInformationFood and Drug Administration-approved medicationsClinical expertsFrequent topicTreatment informationSubstance useMental Health, Substance Use, and Tuberculosis Preventive Therapy in People With HIV: A Prospective Cohort Study
Johnson A, Chimoyi L, Shenoi S, Brault M, Forastiere L, Charalambous S, Chihota V, Davis J. Mental Health, Substance Use, and Tuberculosis Preventive Therapy in People With HIV: A Prospective Cohort Study. Open Forum Infectious Diseases 2025, 12: ofaf303. PMID: 40567997, PMCID: PMC12188208, DOI: 10.1093/ofid/ofaf303.Peer-Reviewed Original ResearchTuberculosis preventive therapyUnhealthy alcohol useMental healthDepressive symptomsAlcohol useTobacco useAssociation of mental healthInfluence of mental healthCohort studyMeasure symptoms of anxietyNegatively associated with adherenceDeductive content analysisMixed methods studySubstance useLongitudinal cohort studyPsychological support servicesSymptoms of anxietySymptoms of depressionPreventive therapyProspective cohort studyAntiretroviral therapyHIV mortalityMultivariate regression modelSubstance use disordersMethods studyImpact of young adult life transitions on adult mental health problems: a propensity score analysis
Copeland W, Prytherch S, Rothenberg W, Godwin J, Gaydosh L, Gutin I, Tong G, Shanahan L. Impact of young adult life transitions on adult mental health problems: a propensity score analysis. Psychological Medicine 2025, 55: e152. PMID: 40384216, PMCID: PMC12094619, DOI: 10.1017/s0033291725001072.Peer-Reviewed Original ResearchConceptsMental health problemsMental health symptomsAdult life transitionsHealth symptomsYoung adults transitionAntisocial personality disorder symptomsLife transitionsAntisocial personality symptomsPersonality disorder symptomsGreat Smoky Mountains StudyAdult mental health problemsChildhood mental health problemsEarly life adversityChildhood mental health symptomsDisorder symptomsLife adversityPersonality symptomsPsychiatric symptomsEmotional symptomsAdult transitionSubstance useHealth problemsMountains StudyYoung adulthoodSymptomsPolygenic risk and childhood adversity as moderators of drug and alcohol withdrawal symptoms
Han A, Davis C, Jinwala Z, SooHoo J, Gelernter J, Feinn R, Kranzler H. Polygenic risk and childhood adversity as moderators of drug and alcohol withdrawal symptoms. Drug And Alcohol Dependence 2025, 273: 112712. PMID: 40449208, DOI: 10.1016/j.drugalcdep.2025.112712.Peer-Reviewed Original ResearchConceptsAdverse childhood eventsSubstance use disordersPolygenic scoresEUR individualsWithdrawal symptomsWithdrawal severityChildhood adversitySubstance useHigher polygenic scoreAssociated with tobaccoDevelopment of substance use disordersSemi-structured diagnostic instrumentMultivariate regression modelReturn to substance useTobacco withdrawal symptomsPolygenic riskManagement of withdrawal symptomsIndividual withdrawal symptomsStop substance useAlcohol withdrawal severitySecondary analysisAlcohol withdrawal symptomsSevere withdrawal symptomsOpioid withdrawal symptomsChildhood eventsLoneliness Among US Veterans With Problematic Substance Use: Results From the National Health and Resilience in Veterans Study
Na P, Pless Kaiser A, McCurdy L, Fischer I, Jeste D, Petrakis I, Potenza M, Pietrzak R. Loneliness Among US Veterans With Problematic Substance Use: Results From the National Health and Resilience in Veterans Study. Journal Of Addiction Medicine 2025 DOI: 10.1097/adm.0000000000001508.Peer-Reviewed Original ResearchProblematic substance useNational Health and ResilienceSocial network sizeCorrelates of lonelinessVeterans StudyDepressive symptomsUS veteransPsychological distressSubstance useLifetime suicide attemptsPosttraumatic stress symptomsThree-Item Loneliness ScaleUS military veteransPurpose in lifeSuicide attemptsStress symptomsPervasive public health problemBurden of lonelinessLikelihood of lonelinessMilitary veteransNationally representative sampleLoneliness ScaleMultivariate logistic regressionPublic health problemLonelinessBeyond User-Centered Design: Designing Digital Health Technologies for Substance Use Prevention and Treatment in Children and Youth
Singh K, Camenga D, Aneni K, Hieftje K. Beyond User-Centered Design: Designing Digital Health Technologies for Substance Use Prevention and Treatment in Children and Youth. 2025, 231-249. DOI: 10.1007/978-3-031-84655-7_10.Peer-Reviewed Original ResearchDigital health interventionsSubstance use preventionHealth interventionsDevelopment of digital interventionsAssociated with numerous adverse health outcomesNumerous adverse health outcomesMental health disordersDigital health technologiesAdverse health outcomesFuture addictionHealth outcomesDigital interventionsSubstance use disordersUser-centered design approachHealth disordersHealth technologiesYouth substance useInterventionIncreased riskSubstance useUse disorderPreventionYouthChildrenUser experience evaluationImplications and Considerations of Sexual and Gender Identities in Dynamic Psychotherapies
Hill K, Qayyum Z, Webster C. Implications and Considerations of Sexual and Gender Identities in Dynamic Psychotherapies. Child And Adolescent Psychiatric Clinics Of North America 2025, 34: 459-470. PMID: 40516956, DOI: 10.1016/j.chc.2025.03.007.Peer-Reviewed Original ResearchConceptsGender-neutral languageSexual identityGender identityDiverse gendersMental health issuesRisk of mental health issuesSubstance useTherapeutic spaceGender diversityGenderIdentitySexualityHealth issuesLesbiansQueerTransgenderMultiple opportunitiesSelf-reflectionYouthIntersexAllianceOpportunitiesSuicideImplicationsTherapeutic allianceExercise Interventions Conducted Among Individuals with Co-occurring HIV and Unhealthy Substance Use: A Systematic Review
Mistler C, Allen W, Grimshaw A, Idiong C, Harsono D, Irwin M, Ash G, S. Pescatello L, Meyer J, Jennifer Edelman E. Exercise Interventions Conducted Among Individuals with Co-occurring HIV and Unhealthy Substance Use: A Systematic Review. AIDS And Behavior 2025, 1-14. PMID: 40289036, DOI: 10.1007/s10461-025-04735-6.Peer-Reviewed Original ResearchUnhealthy substance useExercise interventionRandomized controlled trialsSubstance useCochrane data collection formsEvidence-based exercise interventionsCo-occurring risk factorsSystematic reviewPositive associations with outcomesHome-based trainingCo-occurring HIVRisk factorsLow risk of biasFull-text reviewData collection formRisk of biasQuasi-experimental designAerobic/resistance trainingTai ChiPhysical inactivityPhysical activityCognitive behavioral therapyImprove HIVHealth outcomesBehavioral counselingCollaborating Across the Globe: The Yale-University of Jordan International Interprofessional Addiction Education Program
Muvvala S, Minahan-Rowley R, Al-Khateeb Y, Abu-Dahab R, Khoshnood K, Wazaify M, Tetrault J. Collaborating Across the Globe: The Yale-University of Jordan International Interprofessional Addiction Education Program. Substance Abuse 2025 DOI: 10.1177/29767342251331389.Peer-Reviewed Original ResearchYale School of MedicineSubstance use disordersTraining programJoint training programsHealth care workforceAddiction medicineInternational conference presentationsGlobal public health challengePublic health challengePeer-reviewed articlesCare workforcePublished peer-reviewed articlesInterprofessional educationTreatment gapTreating substance use disordersKern modelSchool of MedicineHealth challengesConference presentationsTraining workshopsTraining opportunitiesEducation programsPublic healthSubstance useTwo-year programRisk Environments of Permanent Supportive Housing for Formerly Incarcerated People with Serious Mental Illnesses: A Protocol for a Novel Mixed Methods Feasibility Study
Kriegel L, Henwood B, McDonell M, Ofer Amram, Bellamy C, Collins S, Salzer M. Risk Environments of Permanent Supportive Housing for Formerly Incarcerated People with Serious Mental Illnesses: A Protocol for a Novel Mixed Methods Feasibility Study. International Journal Of Qualitative Methods 2025, 24 DOI: 10.1177/16094069251337940.Peer-Reviewed Original ResearchPermanent supportive housingIncarcerated peopleSupportive housingRisk environment frameworkCriminal legal systemRates of recidivismGo-along interviewsHigh-poverty environmentsConcurrent mixed-methods studyCriminogenic riskIncarcerated clientsMental illnessPolicy influencePublic spaceCommunity resilience indexPrivate spaceCommunity participationAssociated with positive outcomesSerious mental illnessCommunity integrationMixed-methods studyParticipatory mappingSubstance useLegal systemRisk environmentEmerging Therapeutics in the Treatment of Substance Use Disorders: A Focus on GLP-1 Receptor Agonists, D3R Antagonists, and CRF Antagonists
Draghmeh K, Fuehrlein B. Emerging Therapeutics in the Treatment of Substance Use Disorders: A Focus on GLP-1 Receptor Agonists, D3R Antagonists, and CRF Antagonists. Journal Of Integrative Neuroscience 2025, 24: 26361. PMID: 40302255, DOI: 10.31083/jin26361.Peer-Reviewed Original ResearchConceptsSubstance use disordersCorticotropin-releasing factorTreatment of substance use disordersCorticotropin-releasing factor antagonistTreating substance use disordersDrug-seeking behaviorDopamine D3 receptorGlucagon-like peptide-1Reduce substance useUse of alcoholAddiction processD3R antagonistsReward modulationRelapse preventionD3 receptorsUse disorderStimulant useSubstance useGlucagon-like peptide-1 receptor agonistsPrevent relapseReceptor agonistsTarget different aspectsSignificant public health challengeAntagonistDisordersSubstance Use and Chronic Pain Management: Understanding the Learning Needs of Primary Care Clinicians Through Project ECHO
Katzman J, Warrick B, Takeda M, Bhatt S, Grandhe R, Jacobsohn V, Tomedi L. Substance Use and Chronic Pain Management: Understanding the Learning Needs of Primary Care Clinicians Through Project ECHO. Healthcare 2025, 13: 873. PMID: 40281822, PMCID: PMC12027298, DOI: 10.3390/healthcare13080873.Peer-Reviewed Original ResearchPrimary care cliniciansCare cliniciansFocus groupsPatient centered carePatient-centered careInteractive case discussionCase discussionSubstance useSubstance use managementModified Delphi techniqueClinical practice guidelinesChronic pain managementPost-session surveysProject ECHOHub-teamThematic analysisPain managementPractice guidelinesPrescribed opioidsCore themesDelphi techniqueChronic painOpioid overdoseUS regionsCommunication skillsNovel Elective Course on Substance Use for Pharmacy Students in Jordan
Wazaify M, Al-Khateeb Y, Khoshnood K, Muvvala S, Minahan-Rowley R, Abu-Dahab R, Tetrault J. Novel Elective Course on Substance Use for Pharmacy Students in Jordan. American Journal Of Pharmaceutical Education 2025, 89: 101399. PMID: 40158728, DOI: 10.1016/j.ajpe.2025.101399.Peer-Reviewed Original ResearchConceptsPharmacy studentsHealth professions studentsAverage knowledge scoreSubstance useProfessions studentsBachelor of Pharmacy studentsKnowledge scoresUndergraduate pharmacy studentsDoctor of pharmacyAssess knowledgeElective courseHarm reductionAddiction treatment programsJordanian pharmacistsAddiction medicineFree treatmentSite visitsPositive changesTreatment programsPharmacyLecture-style presentationStudents' attitudesAttitudesPeoplePharmacistsThe Police Opioid Seizure Temporal Risk (POSTeR) model of increased exposure to fatal overdose
Del Pozo B, Green T, Godvin M, Ray B. The Police Opioid Seizure Temporal Risk (POSTeR) model of increased exposure to fatal overdose. International Journal Of Drug Policy 2025, 139: 104789. PMID: 40157153, PMCID: PMC12045107, DOI: 10.1016/j.drugpo.2025.104789.Peer-Reviewed Original ResearchConceptsRisk of fatal overdoseAcute opioid withdrawal symptomsOpioid withdrawal symptomsPrevalence of illicit drugsFatal overdoseIllicit opioidsOutcomes of opioid use disorderOpioid use disorderWithdrawal symptomsUse disorderReduced aversionOpioid dependenceSubstance useBehavioral outcomesPsychological outcomesReduce opioid toleranceIllicit substancesPoliceLocal levelCausal modelPolice seizuresIllicit drugsDrug seizuresQualitative accountsOpioid toleranceExploring the Relationship Between Lifestyle and Post-COVID Psychiatric Symptoms: Findings from a Brazilian Cohort.
Borges S, Roncete G, Amendola F, Zanetti M, Miguel E, Filho G, Forlenza O, Damiano R. Exploring the Relationship Between Lifestyle and Post-COVID Psychiatric Symptoms: Findings from a Brazilian Cohort. American Journal Of Lifestyle Medicine 2025, 15598276251328022. PMID: 40161283, PMCID: PMC11948251, DOI: 10.1177/15598276251328022.Peer-Reviewed Original ResearchPost-traumatic stress disorderGeneralized anxiety disorderCommon mental disordersSuicidal ideationPsychiatric symptomsSeverity of alcohol useAssociated with suicidal ideationContext of depressionPsychiatric well-beingMonths post-hospitalizationAnxiety disordersStress disorderCOVID-19 survivorsMental disordersExtended recovery periodIncreased depressionSubstance useAlcohol useConsumption of sedativesDepressionLifestyle factorsIncreased intake of fruitsIdeationDisordersIntake of fruitsSubstance Misuse, Executive Function, and Young Adult Intimate Partner Violence: Direct and Indirect Pathways.
Martin E, Ramos K, Modanesi E, Mayes L, Stover C. Substance Misuse, Executive Function, and Young Adult Intimate Partner Violence: Direct and Indirect Pathways. Journal Of Interpersonal Violence 2025, 8862605251326641. PMID: 40123291, DOI: 10.1177/08862605251326641.Peer-Reviewed Original ResearchIntimate partner violence riskIntimate partner violenceEarly adolescent substance usePrenatal drug exposureAdolescent substance useExecutive functionSubstance useMaternal educationAdult intimate partner violencePredicting intimate partner violencePrevent intimate partner violenceHigh-risk subjectsYoung adult relationshipsContribution of childhood maltreatmentDevelopmental trajectories of individualsAdolescents' executive functionLow maternal educationWell-being consequencesEnhance executive functionLongitudinal birth cohortYoung adultsDrug exposureIPV riskPartner violenceSex-specific effectsPsychometric properties of the Reward Deficiency Syndrome Questionnaire among a non-clinical sample and its relationship with the characteristics of potentially addictive behaviors
Kotyuk E, Demetrovics Z, Urbán R, Czakó A, Blum K, Griffiths M, Potenza M, Efrati Y. Psychometric properties of the Reward Deficiency Syndrome Questionnaire among a non-clinical sample and its relationship with the characteristics of potentially addictive behaviors. Addictive Behaviors Reports 2025, 21: 100598. PMID: 40248688, PMCID: PMC12005299, DOI: 10.1016/j.abrep.2025.100598.Peer-Reviewed Original ResearchReward Deficiency SyndromeCompulsive buying-shopping disorderInternet gaming disorderAddictive behaviorsBehavioral addictionsGambling disorderDevelopment of addictive behaviorsBuying-shopping disorderNon-clinical samplePotential behavioral addictionsProblematic substance useAssociated with anxietyIsraeli young adultsPsychometrically sound instrumentNatural rewardsCompulsive personalityFactor structureGaming disorderProblematic behaviorsSubstance useSocial media usePersonal characteristicsPsychological featuresSound instrumentHebrew versionThe therapeutic effects of psychedelics for opioid use disorder: A systematic review of clinical studies
Weleff J, Pulido-Saavedra A, Aghaei A, Ing K, Arakelian M, Fontenele R, Nero N, Barnett B, Anand A, Bassir Nia A, Angarita G. The therapeutic effects of psychedelics for opioid use disorder: A systematic review of clinical studies. Psychiatry Research 2025, 348: 116446. PMID: 40147088, DOI: 10.1016/j.psychres.2025.116446.Peer-Reviewed Original ResearchOpioid use disorderStudies of psychedelicsSystematic review of clinical studiesUse disorderReview of clinical studiesTherapeutic effects of psychedelicsEffects of psychedelicsOpioid receptor systemApplications of psychedelicsClinical studiesMu-opioid receptorsNaturalistic studySerotonergic psychedelicsOpioid withdrawalPlacebo-controlled trialPsychedelicsSubstance useUnited States Food and Drug AdministrationStates Food and Drug AdministrationMu-opioidFood and Drug AdministrationSystematic reviewReceptor systemClinical study designDouble-blindTraining School-Based Health Clinicians in New Mexico Regarding Adverse Childhood Experiences
Katzman J, Tomedi L, Chari K, Pandey N, Del Fabbro A, Ramos M, Kazhe-Dominguez B. Training School-Based Health Clinicians in New Mexico Regarding Adverse Childhood Experiences. Healthcare 2025, 13: 638. PMID: 40150488, PMCID: PMC11942032, DOI: 10.3390/healthcare13060638.Peer-Reviewed Original ResearchSchool-based health centersAdverse childhood experiencesHealth professionalsHealth cliniciansTelementoring programRural stateChildhood experiencesPrevalence of adverse childhood experiencesPoor mental healthCapacity-building modelECHO programHealth centersMental healthPre/post surveyCase-based learningChronic painSubstance useHealthCliniciansHigh riskParticipantsProfessionalsTraumatic experiencesYouthProgram
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