2025
Observational and Genetic Analyses of Traumatic Experiences and Endometriosis
Koller D, Løkhammer S, Goroshchuk O, Denner V, Stiltner B, Mitjans M, He J, Taylor H, Lawn R, Koenen K, Polimanti R. Observational and Genetic Analyses of Traumatic Experiences and Endometriosis. JAMA Psychiatry 2025, 82: 386-394. PMID: 39908042, PMCID: PMC11800128, DOI: 10.1001/jamapsychiatry.2024.4694.Peer-Reviewed Original ResearchPolygenic risk scoresLatent class analysisAssociated with increased oddsTraumatic experiencesImpact of childhoodIndividual-level dataCase-control studyStressful eventsGenetic predispositionTrauma-related outcomesUnaffected womenMain OutcomesFinnGen cohortRisk scoreAssociation of endometriosisPosttraumatic stress disorderTrauma eventsMeta-analysisSexual traumaAssociated with endometriosisContact traumaPotential associationStress disorderPsychological traumaPhenotypic associations
2024
Negative Life Events and Emotional Symptoms From Ages 2 to 30 Years
Copeland W, Keen R, Tong G, Shanahan L. Negative Life Events and Emotional Symptoms From Ages 2 to 30 Years. JAMA Network Open 2024, 7: e2429448. PMID: 39207754, PMCID: PMC11362870, DOI: 10.1001/jamanetworkopen.2024.29448.Peer-Reviewed Original ResearchConceptsCross-sectional analysisEmotional symptomsNegative life eventsAssociated with emotional symptomsLife eventsYoung adulthoodAssociated with increased mental health symptomsCohort study analyzed dataStressful eventsTraumatic eventsMental health symptomsCross-sectional associationsLongitudinal analysisAged 2Years of follow-upStudy analyzed dataDevelopmental periodIndividuals aged 2Lifetime traumatic eventsHealth symptomsMain OutcomesLate adolescenceEmotional functioningCohort studyPrimary outcome
2023
Hippocampal Mechanisms Support Cortisol-Induced Memory Enhancements
Sherman B, Harris B, Turk-Browne N, Sinha R, Goldfarb E. Hippocampal Mechanisms Support Cortisol-Induced Memory Enhancements. Journal Of Neuroscience 2023, 43: 7198-7212. PMID: 37813570, PMCID: PMC10601369, DOI: 10.1523/jneurosci.0916-23.2023.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingMemory enhancementEpisodic memoryAssociative memoryEpisodic memory encodingBrain regionsHigh-resolution functional magnetic resonance imagingHuman hippocampusHigh-resolution fMRIStress-related hormone cortisolHormone cortisolMemory benefitsEmotional memoryMemory encodingEmotional eventsEmotional associationsHippocampal representationsHippocampal signaturesFunctional neuroimagingHippocampal mechanismsStressful eventsFunctional connectivityHippocampal functionMemory formationSalient informationStressful life events and incident depression among U.S. military personnel
Sampson L, Gradus J, Cabral H, Rosellini A, Fink D, Cohen G, Liberzon I, Galea S. Stressful life events and incident depression among U.S. military personnel. Social Psychiatry And Psychiatric Epidemiology 2023, 58: 1009-1018. PMID: 36897335, PMCID: PMC10619516, DOI: 10.1007/s00127-023-02445-9.Peer-Reviewed Original ResearchConceptsPast-year stressorsStressful life eventsRates of depressionLife eventsIncident depressionStressful eventsRate of incident depressionNational Guard membersLife stressorsU.S. military personnelAnalysis of effect modificationStressful experiencesDepressionGuard membersNo stressful eventsDynamic cohort studyExploratory analysisStressorsDual roleCivilian lifeU.S. militaryMilitary personnelEffect modificationHigher incomeIncomeUsing Social Media for Social Motives Moderates the Relationship between Post-Traumatic Symptoms during a COVID-19-Related Lockdown and Improvement of Distress after Lockdown
Buodo G, Moretta T, Santucci V, Chen S, Potenza M. Using Social Media for Social Motives Moderates the Relationship between Post-Traumatic Symptoms during a COVID-19-Related Lockdown and Improvement of Distress after Lockdown. Behavioral Sciences 2023, 13: 53. PMID: 36661625, PMCID: PMC9855109, DOI: 10.3390/bs13010053.Peer-Reviewed Original ResearchPost-traumatic symptomsGeneral distress symptomsGeneral distressSocial motivesTime 1Distress symptomsPost-traumatic stress symptomsLongitudinal studyProtective/risk factorsRole of motivesStress symptomsPsychological distressPossible moderatorsTime 2Stressful eventsSocial interactionCOVID-19-related lockdownMental healthSM useSocial connectionsDistressPrevious researchSocial media useOnline surveyMedia use
2022
City-wide study of laboratory-confirmed COVID-19 cases in San Antonio: An investigation of stressful events accompanying infection and their relation to psychosocial functioning
Tsai J, Grace A, North C, Pietrzak R, Vazquez M, Kurian A. City-wide study of laboratory-confirmed COVID-19 cases in San Antonio: An investigation of stressful events accompanying infection and their relation to psychosocial functioning. Psychiatry Research 2022, 320: 115012. PMID: 36565515, PMCID: PMC9762912, DOI: 10.1016/j.psychres.2022.115012.Peer-Reviewed Original ResearchConceptsPsychosocial functioningStressful eventsStress-related symptomsPsychological symptomsLong-term psychological effectsStress-related psychological symptomsImpaired psychosocial functioningWorse psychosocial functioningStress-related psychological problemsPsychological healthPsychological effectsPsychological problemsCOVID-19 infectionFunctioningPhysical symptomsOnline assessmentLaboratory-confirmed COVID-19 casesCity-wide studyAdultsTargeted supportSymptomsFearFinancial problemsCOVID-19 casesParticipantsSOCIAL SUPPORT AND STRAIN AS PREDICTORS OF MULTIMORBIDITY FOLLOWING A MARITAL TRANSITION
Denning E, Newsom J, Botoseneanu A, Allore H, Nagel C, Dorr D, Quiñones A. SOCIAL SUPPORT AND STRAIN AS PREDICTORS OF MULTIMORBIDITY FOLLOWING A MARITAL TRANSITION. Innovation In Aging 2022, 6: 567-567. PMCID: PMC9770881, DOI: 10.1093/geroni/igac059.2136.Peer-Reviewed Original ResearchMore chronic conditionsChronic conditionsPredictors of multimorbiditySocial supportAdults age 50Race/ethnicityAge 50Multimorbidity trajectoriesOlder adultsMarital transitionsHealth declineSocial strainStressful eventsRetirement StudyChildrenSpousal supportGrowth curve modelingPiecewise growth curve modelingHealthLtParticipantsMultimorbidityCoping, symptoms, and insomnia among people with heart failure during the COVID-19 pandemic
O’Connell M, Jeon S, Conley S, Linsky S, Redeker NS. Coping, symptoms, and insomnia among people with heart failure during the COVID-19 pandemic. European Journal Of Cardiovascular Nursing 2022, 22: 291-298. PMID: 35938348, PMCID: PMC9384676, DOI: 10.1093/eurjcn/zvac072.Peer-Reviewed Original ResearchConceptsSleep-related cognitionsCognitive behavioral therapySleep characteristicsPandemic-related stressPandemic-related stressorsSymptoms of anxietyInvoluntary engagementInvoluntary disengagementBehavioral therapyStressful eventsSleep problemsInsomnia severityMood disturbanceCopingCOVID-19 pandemicSecondary controlAnxietyCognitionParticipantsDaytime symptomsHeart failureInsomniaDepressionPeopleCBTSleep, Stress, and Symptoms Among People With Heart Failure During the COVID-19 Pandemic
O'Connell M, Jeon S, Conley S, Linsky S, Redeker NS. Sleep, Stress, and Symptoms Among People With Heart Failure During the COVID-19 Pandemic. The Journal Of Cardiovascular Nursing 2022, 38: e55-e60. PMID: 35324509, PMCID: PMC9508278, DOI: 10.1097/jcn.0000000000000906.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyBehavioral therapySleep-related cognitionsHeart failureSelf-reported sleep characteristicsStressful eventsEffects of stressCOVID-19 pandemicMental healthMonths post treatmentSelf-management educationSleep characteristicsMoodSleepChronic conditionsInsomniaSymptomsTherapyPeopleCognitionCopingPost treatmentAnxietyPandemicSignificant improvementSpecific and cumulative lifetime stressors in the aetiology of major depression: A longitudinal community-based population study
Su Y, D'Arcy C, Li M, O'Donnell K, Caron J, Meaney M, Meng X. Specific and cumulative lifetime stressors in the aetiology of major depression: A longitudinal community-based population study. Epidemiology And Psychiatric Sciences 2022, 31: e3. PMID: 35078547, PMCID: PMC8851045, DOI: 10.1017/s2045796021000779.Peer-Reviewed Original ResearchConceptsGenetic predispositionSubsequent depressionStressful life eventsLifetime stressorsLongitudinal community-based cohort studyPsychosocial stressorsCommunity-based cohort studyCommunity-based population studyStressful eventsMental illness preventionMultivariate logistic regressionHealth-related factorsDevelopment of depressionChildhood maltreatmentMental health promotionEtiology of depressionPresent studyStressful experiencesLife eventsChild-parent bondingCumulative stressful experiencesSouthwest of MontrealPolygenetic risk scoresCohort studySocio-demographic characteristics
2021
Cohort profile: the Ohio Army National Guard Mental Health Initiative (OHARNG-MHI)
Sampson L, Cohen G, Fink D, Conroy C, Calabrese J, Wryobeck J, Elhai J, King A, Liberzon I, Galea S. Cohort profile: the Ohio Army National Guard Mental Health Initiative (OHARNG-MHI). Social Psychiatry And Psychiatric Epidemiology 2021, 56: 2107-2116. PMID: 34480595, PMCID: PMC8577754, DOI: 10.1007/s00127-021-02166-x.Peer-Reviewed Original ResearchConceptsMental disordersNational Guard membersOhio Army National Guard Mental Health InitiativePast-year mental disordersConsequences of mental disordersGuard membersSubstance use disordersLatent class growth analysisTelephone Screening InstrumentMental health servicesPsychiatric comorbidityPosttraumatic stressDepressive symptomsMental health initiativesChildhood eventsCombat deploymentStressful eventsScreening instrumentAlcohol useDisordersFollow-up interviewsStructured telephone interviewUnited States militaryMilitary serviceHealth initiativesPelvic Examinations in the Adolescent and Young Adult Population: A Commentary on Why and When
Ahuja C, Cron J. Pelvic Examinations in the Adolescent and Young Adult Population: A Commentary on Why and When. Journal Of Pediatric And Adolescent Gynecology 2021, 34: 783-786. PMID: 34284079, DOI: 10.1016/j.jpag.2021.07.004.Peer-Reviewed Original ResearchConceptsUS Preventive Services Task ForcePatient-provider relationshipPelvic examinationAmerican CollegeInternal pelvic examinationYoung adult patientsYoung adult populationAsymptomatic patientsAdult patientsSpeculum examinationAsymptomatic adolescentsAdult populationAmerican AcademyPatientsStressful eventsExaminationAdolescentsTask ForcePractice utilityNonthreatening environmentGynecologistsObstetriciansPediatricsPhysiciansProfessional organizationsCoping Strategies, Neural Structure, and Depression and Anxiety During the COVID-19 Pandemic: A Longitudinal Study in a Naturalistic Sample Spanning Clinical Diagnoses and Subclinical Symptoms
Holt-Gosselin B, Tozzi L, Ramirez CA, Gotlib IH, Williams LM. Coping Strategies, Neural Structure, and Depression and Anxiety During the COVID-19 Pandemic: A Longitudinal Study in a Naturalistic Sample Spanning Clinical Diagnoses and Subclinical Symptoms. Biological Psychiatry Global Open Science 2021, 1: 261-271. PMID: 34604834, PMCID: PMC8479487, DOI: 10.1016/j.bpsgos.2021.06.007.Peer-Reviewed Original ResearchAnxious arousal symptomsMaladaptive coping strategiesArousal symptomsCoping strategiesSubclinical symptomsBrain regionsNeural structuresGray matter volumePreregistered hypothesesNeural factorsAnhedonia symptomsStressful eventsDepression symptomsGeneral linear mixed-effects modelsNaturalistic sampleLongitudinal studyMatter volumeAmygdala volumeAnxietyLower structural integrityCOVID-19 pandemicT1-weighted scansCortical thicknessPsychiatric diagnosisClinical symptoms
2019
The role of acetylcholine in negative encoding bias: Too much of a good thing?
Mineur YS, Picciotto MR. The role of acetylcholine in negative encoding bias: Too much of a good thing? European Journal Of Neuroscience 2019, 53: 114-125. PMID: 31821620, PMCID: PMC7282966, DOI: 10.1111/ejn.14641.Peer-Reviewed Original ResearchConceptsPotential neural pathwaysSymptoms of anxietyAffective processesSustained attentionStressful eventsCore symptomsFacilitate learningAppropriate learningNeural pathwaysRole of acetylcholineGood thingLevels of AChLearningDepressionBiasDepressive episodeNeuromodulatory roleCholinergic signalingAnimal studiesAnxietyMemoryAcetylcholine SignalingHigh levelsEncodingAChA day-by-day prospective analysis of stress, craving and risk of next day alcohol intake during alcohol use disorder treatment
Wemm SE, Larkin C, Hermes G, Tennen H, Sinha R. A day-by-day prospective analysis of stress, craving and risk of next day alcohol intake during alcohol use disorder treatment. Drug And Alcohol Dependence 2019, 204: 107569. PMID: 31574406, PMCID: PMC6916671, DOI: 10.1016/j.drugalcdep.2019.107569.Peer-Reviewed Original ResearchConceptsAlcohol use disorderAlcohol intakeEarly treatmentAlcohol use disorder treatmentStressful eventsNovel treatment approachesAlcohol relapse riskUse disorder treatmentNext dayWeeks of outpatientStress-induced cravingAlcohol use outcomesRelapse riskProspective analysisUse disordersAUD patientsTreatment approachesDisorder treatmentHigher cravingDaily diariesUse outcomesIntakeAUD individualsCravingDrinking amount
2018
Stressful Life Events in Young Adults With Type 1 Diabetes in the U.S. T1D Exchange Clinic Registry
Joiner KL, Holland ML, Grey M. Stressful Life Events in Young Adults With Type 1 Diabetes in the U.S. T1D Exchange Clinic Registry. Journal Of Nursing Scholarship 2018, 50: 676-686. PMID: 30246919, PMCID: PMC6788928, DOI: 10.1111/jnu.12428.Peer-Reviewed Original ResearchConceptsStressful life eventsT1D Exchange Clinic RegistryInsulin dosesGlycemic controlType 1 diabetesLife eventsClinic registryYoung adultsRecent stressful life eventsPoor glycemic controlMean A1C levelsTime of enrollmentSingle self-report itemDescriptive secondary analysisSelf-report itemsA1c levelsHemoglobin levelsMeasures of frequencyStressful eventsSecondary analysisMediation analysisDosesDichotomous variablesPositive approachEvent indexPsychological stress and psoriasis: a systematic review and meta‐analysis
Snast I, Reiter O, Atzmony L, Leshem Y, Hodak E, Mimouni D, Pavlovsky L. Psychological stress and psoriasis: a systematic review and meta‐analysis. British Journal Of Dermatology 2018, 178: e363-e363. DOI: 10.1111/bjd.16620.Peer-Reviewed Original ResearchPsychological stressStressful eventsRecalled stressful eventsLack of robust evidencePsoriasis patientsDiagnosis of stress disordersChronic inflammatory skin diseaseInfluence of psychological stressPatient recallWorsening of psoriasisInflammatory skin diseaseStress disorderPatient's memoryEvaluate disease severityRobust evidencePsoriasis onsetPsoriasis severityPsoriasisPatientsControl groupDisease severitySkin diseasesPsychological stress and psoriasis: a systematic review and meta‐analysis
Snast I, Reiter O, Atzmony L, Leshem Y, Hodak E, Mimouni D, Pavlovsky L. Psychological stress and psoriasis: a systematic review and meta‐analysis. British Journal Of Dermatology 2018, 178: 1044-1055. PMID: 29124739, DOI: 10.1111/bjd.16116.Peer-Reviewed Original ResearchConceptsCase-control studyOdds ratioPsychological stressExacerbation of psoriasisOnset of psoriasisCross-sectional studyStress disorder diagnosisStressful eventsPsoriasis exacerbationRetrospective studyCohort studySystematic reviewMeta-analysesPsoriasisCochrane LibraryMeta-analysisPatientsExacerbationDisorder diagnosisStress reactivityAssociationSurveyStress levelsPsycINFOOdds
2017
2341
Vaughan C, Stangl B, Sinha R, Ramchandani V. 2341. Journal Of Clinical And Translational Science 2017, 1: 36-36. PMCID: PMC6798883, DOI: 10.1017/cts.2017.132.Peer-Reviewed Original ResearchChronic stressful eventsDrug Effects QuestionnaireNon-dependent drinkersAlcohol Urge QuestionnaireStress interviewStressful eventsChronic stressorsEarly life stress eventsBetter treatment outcomesChronic stress scoresAlcohol use disorderEarly life stressImpact of stressLife eventsRecent life eventsLife stress eventsImpaired Control ScaleMore chronic stressorsAlcohol infusionIntravenous alcoholTreatment outcomesPriming exposureLife Stress QuestionnaireUse disordersEffects Questionnaire
2016
Associations of Gender, Smoking, and Stress with Transitions in Major Depression Diagnoses.
Verplaetse TL, Smith PH, Pittman BP, Mazure CM, McKee SA. Associations of Gender, Smoking, and Stress with Transitions in Major Depression Diagnoses. The Yale Journal Of Biology And Medicine 2016, 89: 123-9. PMID: 27354839, PMCID: PMC4918874.Peer-Reviewed Original ResearchConceptsMajor depression diagnosisFormer smokersDepression diagnosisMDD diagnosisMore stressful eventsStressful eventsFormer cigarette smokersU.S. National Epidemiologic SurveyCigarette smoking statusNational Epidemiologic SurveyAssociation of genderCurrent smokingSmoking statusCigarette smokersClinical assessmentDepression riskEpidemiologic SurveyLife event stressRelated conditionsSmokersSmokingDiagnosisBiological underpinningsEvent stressHigh rate
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