2025
Suicide risk in persons with polycystic ovarian syndrome: a systematic review
Wong S, Le G, Lo H, Cao B, Lim P, Rhee T, Ho R, Guillen-Burgos H, Teopiz K, Phan L, Rosenblat J, Zhang M, McIntyre R. Suicide risk in persons with polycystic ovarian syndrome: a systematic review. Annals Of General Psychiatry 2025, 24: 38. PMID: 40457354, PMCID: PMC12128235, DOI: 10.1186/s12991-025-00574-w.Peer-Reviewed Original ResearchIncreased risk of suicidal ideationRisk of suicidal ideationSuicidal ideationSuicide riskPsychiatric comorbiditiesPresence of mental illnessPrevalence of suicidal ideationIncreased risk of depressionRisk of depressionOvarian syndromePCOS populationPsychiatric comorbiditySuicidal behaviorSuicide attemptsCompleted suicideIncreased suicidalitySuicide outcomesSelf-harmMental illnessBackgroundPolycystic ovarian syndromeIdeationSuicidePolycystic ovarian syndromeDiagnosis of PCOSResearch vistasHigh rates of suicidality and parasuicidal behavior in individuals at clinical high-risk for psychosis: Implications for suicide risk assessment and suicide prevention
Trujillo T, Mirzakhanian H, Addington J, Bearden C, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Walker E, Woods S, Cadenhead K. High rates of suicidality and parasuicidal behavior in individuals at clinical high-risk for psychosis: Implications for suicide risk assessment and suicide prevention. Schizophrenia Research 2025, 281: 1-9. PMID: 40300257, DOI: 10.1016/j.schres.2025.04.030.Peer-Reviewed Original ResearchConceptsClinical high riskCalgary Depression Scale for SchizophreniaClinical high-risk youthSuicide risk assessmentParasuicidal behaviorSuicidal ideationLife eventsSelf-harmNorth American Prodrome Longitudinal StudyClinical high-risk participantsStructured Assessment of Violence RiskAssessment of Violence RiskClinical high-risk groupHealthy controlsRates of suicidal ideationHistory of self-harmHistory of SILevels of suicidalityStressful life eventsPredictors of SIRates of suicideAssociated with worse symptomsCHR participantsPsychotic conversionDSM diagnosesA cohort study of predictors of short-term nonfatal suicidal and self-harm events among individuals with mental health disorders treated in the emergency department
Marcus S, Cullen S, Schmutte T, Xie M, Liu T, Ungar L, Cardamone N, Williams N, Olfson M. A cohort study of predictors of short-term nonfatal suicidal and self-harm events among individuals with mental health disorders treated in the emergency department. Journal Of Psychiatric Research 2025, 186: 458-468. PMID: 40318538, DOI: 10.1016/j.jpsychires.2025.04.035.Peer-Reviewed Original ResearchConceptsSelf-harm eventsMental health disordersED visitsHealth disordersBulimia nervosaEmergency departmentNonfatal suicideDiagnosis of bulimia nervosaElectronic health record dataSuicidal self-harmEmergency mental healthcareSuicide-related eventsLogistic regressionHealth record dataMental health diagnosesEmergency department visitsMental health problemsVisits of individualsSuicidal symptomsMental healthcareED episodesHealth recordsSelf-harmShort-term riskHealth diagnosisEditorial: Where are the Trials on Adolescent Self-Harm and Suicide?
Kumpf K, Bloch M. Editorial: Where are the Trials on Adolescent Self-Harm and Suicide? Journal Of The American Academy Of Child & Adolescent Psychiatry 2025 PMID: 40088968, DOI: 10.1016/j.jaac.2025.03.002.Peer-Reviewed Original ResearchNonsuicidal self-injurySelf-harmModerators of treatment effectsRandomized controlled trialsPublic health problemEvidence-based treatmentsAdolescent self-harmPrevent self-harmSelf-injuryHealth problemsRandom-effects meta-analysisRandom-effects meta-analysis of studiesTherapeutic interventionsSuicideMeta-analysis of studiesSource of morbidityAdolescentsIndividual patient dataSecondary analysisTreatment effectsNo significant differenceControlled trialsAggregate dataMeta-analysisEffective treatmentA multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis
Peng P, Hao Y, Zhang X, Ma Y, Liu X, Shen D, Shen W, Zhao B, Li D, Beck S, Nunez Y, Potenza M, Gelernter J, Liu T, Yang B. A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis. Annals Of General Psychiatry 2025, 24: 12. PMID: 40033412, PMCID: PMC11877697, DOI: 10.1186/s12991-025-00546-0.Peer-Reviewed Original ResearchSemi-Structured Assessment for Drug Dependence and AlcoholismDSM-5 diagnostic criteriaGambling disorderDSM-5Antisocial personality disorderMethamphetamine use disorderSubstance use disordersDiagnostic criteriaPersonality disorderBridge symptomsDepressive episodeDrug rehabilitation centersCentral symptomsPsychiatric diagnosisGambling durationUse disorderSelf-harmChildhood experiencesMethamphetamineAlcohol useViolent experiencesDisordersManifest symptomsChinese versionMDEPsychosocial Burden and Suicidality in Epilepsy: A Public Health Concern.
Kiriakopoulos E, Chu F, Salpekar J, Baslet G, Ghearing G, Altalib H, Sajatovic M. Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern. Epilepsy Currents 2025, 15357597251318577. PMID: 40028187, PMCID: PMC11869224, DOI: 10.1177/15357597251318577.Peer-Reviewed Original ResearchPsychosocial burdenSelf-harmPublic health concernEvidence-based suicide prevention strategiesHealth concernSuicide prevention strategiesSocial stressorsHigh riskGlobal public health concernMultidisciplinary cliniciansSuicide preventionPrevention strategiesGeneral populationAdjunctive supportSuicide riskIncreased riskIdentification of patientsEarly identificationSuicideBurdenRiskFunctional seizuresPeoplePatient subpopulationsPsychosocialSystematic Review and Individual Participant Data Meta-Analysis: Reducing Self-Harm in Adolescents: Pooled Treatment Effects, Study, Treatment and Participant Moderators
Wright-Hughes A, Farrin A, Fonagy P, Ougrin D, Stahl D, Wright J, Irving D, Mughal F, Truscott A, Diggins E, Chanen A, Cooney E, Carter G, Clover K, Dadds M, Diamond G, Esposito-Smythers C, Green J, Griffiths H, Hassanian-Moghaddam H, Hatcher S, Hazell P, Husain N, Kaess M, King C, Morthorst B, O'Connor R, Santamarina-Perez P, Tyrer P, Walwyn R, Cottrell D. Systematic Review and Individual Participant Data Meta-Analysis: Reducing Self-Harm in Adolescents: Pooled Treatment Effects, Study, Treatment and Participant Moderators. Journal Of The American Academy Of Child & Adolescent Psychiatry 2025 PMID: 39892472, DOI: 10.1016/j.jaac.2025.01.017.Peer-Reviewed Original ResearchIndividual-Participant-DataRepeat self-harmSelf-harmEffective interventionsIPD meta-analysisMeta-analysisCore set of outcome measuresSet of outcome measuresMeta-analysesRepetition of self-harmIntervention to controlIPD meta-analysesMonths post-randomizationMeta-analysis of randomised controlled trialsSelf-harm episodesHistory of self-harmMeta-analysis of RCTsPooled treatment effectsTherapeutic intervention effectivenessSelf-harm incidentsData meta-analysisHeterogeneity of treatment effectsPublic health concernTreatment effectsIntervention effects
2024
Help-Seeking and Disclosure in University Students with Suicidal Thoughts and Self-Harm: A Systematic Review
Barnett P, Tickell A, Osborn T, Delamain H, Fonagy P, Pilling S, Gibbon L. Help-Seeking and Disclosure in University Students with Suicidal Thoughts and Self-Harm: A Systematic Review. International Journal Of Mental Health And Addiction 2024, 1-78. DOI: 10.1007/s11469-024-01416-8.Peer-Reviewed Original ResearchHelp-seekingSelf-harmSuicidal thoughtsRates of help-seekingImprove help-seekingSuicide prevention effortsEthnic minority groupsAt-risk groupsPopulation-basedMental healthReview synthesises researchQualitative studyPrevention effortsSystematic reviewPredictive of completed suicideAt-riskUniversity studentsMinority groupsUS-basedSuicidePsycEXTRAPsychINFOHealthMEDLINEInterventionCultivating participatory processes in self‐harm app development: A case‐study and working methodology
Babbage C, Lockwood J, Roberts L, Mendes J, Greenhalgh C, Willingham L, Wokomah E, Woodcock R, Slovak P, Townsend E, Townsend E, Hollis C, Gregory J, Vallejos E, Woodcock R, Fonagy P, Arseneault L, Doherty S, Willingham L, Creswell C, Lloyd E, De Alcantara Mendes J, Holter C, Jirotka M, Patalay P, Kelly Y, Kandola A, Sonuga‐Barke E, Livingstone S, Kostryka‐Allchorne K, Stoilova M, O'Connor R, Auer D, Lee S, Jawahar N, Etherson M, Greenhalgh C, Sayal K, Warren J, Wanniarachchi V, Stallard P, Hall C, Lucassen M, Merry S, Stasiak K, Babbage C, Parker A, Griffiths H, Roberts L, Slovak P, Williams A, Lockwood J. Cultivating participatory processes in self‐harm app development: A case‐study and working methodology. JCPP Advances 2024, 4: e12295. PMID: 39734924, PMCID: PMC11669782, DOI: 10.1002/jcv2.12295.Peer-Reviewed Original ResearchSelf-harmManagement of self-harmSuicide related behaviorsAdolescent self-harmMental health developmentDigital mental healthMental healthYoung peopleRelated behaviorsPatient involvementFace-to-faceClinical supportHealth developmentCodesign processParticipatory practicesParticipatory aspectsDecision-makingClinical settingClinical toolClinical characteristics associated with problematic pornography use among individuals seeking treatment for opioid use disorder
Stefanovics E, Kraus S, Madden L, Farnum S, Cannata E, Potenza M, Barry D. Clinical characteristics associated with problematic pornography use among individuals seeking treatment for opioid use disorder. Journal Of Behavioral Addictions 2024, 13: 938-946. PMID: 39298267, PMCID: PMC11737410, DOI: 10.1556/2006.2024.00037.Peer-Reviewed Original ResearchBrief Pornography ScreenOpioid use disorderPornography useOpioid use disorder treatmentUse disorderMeasures of substance useMeasures of impulsivityProblematic pornography useMinority of individualsNegative urgencyPositive urgencyPsychotic symptomsSelf-reported dataBehavioral addictionsGambling disorderPsychiatric disordersPsychiatric symptomsSensation-seekingEmotional labilitySelf-harmSubstance useDisordersOpioidIndividualsSymptomsInterventions to reduce harms related to drug use among people who experience incarceration: systematic review and meta-analysis
Macdonald C, Macpherson G, Leppan O, Tran L, Cunningham E, Hajarizadeh B, Grebely J, Farrell M, Altice F, Degenhardt L. Interventions to reduce harms related to drug use among people who experience incarceration: systematic review and meta-analysis. The Lancet Public Health 2024, 9: e684-e699. PMID: 39214637, PMCID: PMC11996259, DOI: 10.1016/s2468-2667(24)00160-9.Peer-Reviewed Original ResearchConceptsOpioid agonist treatmentDrug useRisk behaviorsReducing re-arrestsTherapeutic community interventionsEffectiveness of interventionsRecidivism outcomesReduce injection risk behaviorExperience incarcerationRe-arrestIncarcerationService provisionRecidivismPrisonSystematic reviewCommunity interventionsSubstance useSelf-harmInjection risk behaviorsRandom-effects meta-analysesMeta-analysisAlcohol useSyringe sharingPooled odds ratioRisk of deathReducing self-harm in adolescents: the RISA-IPD individual patient data meta-analysis and systematic review
Cottrell D, Wright-Hughes A, Farrin A, Walwyn R, Mughal F, Truscott A, Diggins E, Irving D, Fonagy P, Ougrin D, Stahl D, Wright J. Reducing self-harm in adolescents: the RISA-IPD individual patient data meta-analysis and systematic review. Health Technology Assessment 2024, 1-42. PMID: 39024118, DOI: 10.3310/gtnt6331.Peer-Reviewed Original ResearchRepetition of self-harmNational Institute for Health and Care ResearchIndividual patient data meta-analysisPatient data meta-analysisData meta-analysisSelf-harmSample of participantsSystematic reviewMeta-analysisMeta-analysesPrimary outcomeRisk of bias assessmentLow risk of biasHistory of self-harmPreferred Reporting ItemsReduce self-harmRandomised controlled trialsRisk of biasConventional meta-analysesIndividual Patient DataCare researchPublic health concernEligible participantsClinical servicesIssues of research designLithium reduces impulsive decision making in transdiagnostic patients at high risk for suicide attempt recurrence: A randomized, double blind, placebo-controlled, crossover study
Murphy N, Pham G, Weyland A, Engelhardt J, Kypriotakis G, Thomas Y, Kosten T, Moukaddam N, Mathew S, Swann A. Lithium reduces impulsive decision making in transdiagnostic patients at high risk for suicide attempt recurrence: A randomized, double blind, placebo-controlled, crossover study. Journal Of Affective Disorders Reports 2024, 17: 100833. DOI: 10.1016/j.jadr.2024.100833.Peer-Reviewed Original ResearchImmediate memory taskInternal State ScaleTime perception tasksSuicidal behaviorImpulsive decisionsSuicide attemptsResponse latencySpectrum of suicidal behaviorsLethal suicidal behaviorMeasures of impulsivityLithium doseConservative response biasSevere suicide attemptsDouble-blind crossover designRandomized double-blind crossover designPrevent suicide riskEffects of lithiumPill placeboMemory taskBehavioral therapySuicide riskResponse biasAdjunctive behavioral therapySelf-harmAssociated with attemptsPsychosocial Evaluation of Living Kidney Donors: A Survey of Current Practices in the United States
Clifton E, Winder G, Lentine K, Zimbrean P, Yadav A, Rubman S, Kalil R, Kumar V, Prashar R, Gan G, Deng Y, Joyce M, Holmes R, Laflen J, Bakhai D, Liapakis A, Doshi M. Psychosocial Evaluation of Living Kidney Donors: A Survey of Current Practices in the United States. Transplantation 2024, 108: e382-e389. PMID: 38867351, DOI: 10.1097/tp.0000000000005095.Peer-Reviewed Original ResearchSubstance use disordersUse disorderActive anxiety disorderMental healthPosttraumatic stress disorderPsychosocial teamAnxiety disordersStress disorderActive suicidalitySelf-harmActivity depressionDisordersPsychosocial assessmentDepressionPsychosocial evaluationPost-donationUnited StatesClinical toolPsychosisLiving kidney donorsCannabisAnxietySuicideAbsolute contraindicationBest practicesExtreme Risk Protection Orders in Connecticut, 2013-2020.
Kapoor R, Viereck B, Lin H, Swanson J, Easter M, Baranoski M, Zeoli A, Frattaroli S, Norko M. Extreme Risk Protection Orders in Connecticut, 2013-2020. The Journal Of The American Academy Of Psychiatry And The Law 2024, 52: 165-175. PMID: 38824428, DOI: 10.29158/jaapl.240022-24.Peer-Reviewed Original ResearchConceptsExtreme risk protection ordersRisk protection ordersProtection ordersRemoval of firearmsPrevalence of mental illnessTwenty-one statesDistrict of ColumbiaLegal outcomesLaw implementationInterpersonal violenceSelf-harmMental illnessLawFirearmResponse to concernsTemporary removalImminent riskConnecticutStatutesSignificant gender differencesViolenceAlcohol useGender differencesOrderStateNational Trends in Emergency Department Visits for Suicide Attempts and Intentional Self-Harm
Bommersbach T, Olfson M, Rhee T. National Trends in Emergency Department Visits for Suicide Attempts and Intentional Self-Harm. American Journal Of Psychiatry 2024, 181: 741-752. PMID: 38831705, DOI: 10.1176/appi.ajp.20230397.Peer-Reviewed Original ResearchEmergency department visitsIntentional self-harmTotal emergency department visitsDepartment visitsSelf-harm visitsVisits per capitaSelf-harmContinuum of mental health careNational Hospital Ambulatory Medical Care SurveyReason-for-visit codesProportion of emergency department visitsMental health careReason-for-visitSuicide attemptsMental health professionalsDrug-related diagnosesDischarge diagnosis codesCo-occurring diagnosesNational Sample SurveyCare SurveyHealth professionalsHealth careSociodemographic groupsDiagnosis codesEmergency departmentImproving Emergency Department Care for Suicidality in Autism: Perspectives from Autistic Youth, Caregivers, and Clinicians
Cervantes P, Palinkas L, Conlon G, Richards-Rachlin S, Sullivan K, Baroni A, Horwitz S. Improving Emergency Department Care for Suicidality in Autism: Perspectives from Autistic Youth, Caregivers, and Clinicians. Journal Of Autism And Developmental Disorders 2024, 1-14. PMID: 38819705, DOI: 10.1007/s10803-024-06364-9.Peer-Reviewed Original ResearchEmergency departmentSuicide risk assessment toolsEmergency department careSuicide risk screeningSuicide riskNon-autistic youthAutistic youthRisk assessment toolSemi-structured interviewsED careImprove careProviding careED settingRisk screeningFamily involvementParticipants' perspectivesCareSelf-harmAssessment toolSystem issuesAutistic patientsDevelopment of recommendationsPilot studyCaregiversSuicidal ideationThe relationship between type, timing and duration of exposure to adverse childhood experiences and adolescent self‐harm and depression: findings from three UK prospective population‐based cohorts
Farooq B, Russell A, Howe L, Herbert A, Smith A, Fisher H, Baldwin J, Arseneault L, Danese A, Mars B. The relationship between type, timing and duration of exposure to adverse childhood experiences and adolescent self‐harm and depression: findings from three UK prospective population‐based cohorts. Journal Of Child Psychology And Psychiatry 2024, 65: 1369-1387. PMID: 38613494, PMCID: PMC7616850, DOI: 10.1111/jcpp.13986.Peer-Reviewed Original ResearchAdverse childhood experiencesMillennium Cohort StudyExposure to adverse childhood experiencesSelf-harmChildhood experiencesACE typesAvon Longitudinal Study of ParentsProspective population-based cohortRisk of self-harmLongitudinal Study of ParentsCo-occurring depressionImpact of adverse childhood experiencesParental mental health problemsStructured life course modeling approachAdolescent self-harmAvon Longitudinal StudyMental health problemsPopulation-based cohortStudy of ParentsMultinomial logistic regression modelLogistic regression modelsMiddle childhoodImpact of developmental timingLong duration of exposureDepressionAn exploratory study of the prevalence and adverse associations of in-school traditional bullying and cyberbullying among adolescents in Connecticut
Rostam-Abadi Y, Stefanovics E, Zhai Z, Potenza M. An exploratory study of the prevalence and adverse associations of in-school traditional bullying and cyberbullying among adolescents in Connecticut. Journal Of Psychiatric Research 2024, 173: 372-380. PMID: 38593696, PMCID: PMC12178578, DOI: 10.1016/j.jpsychires.2024.03.033.Peer-Reviewed Original ResearchConceptsBullying statusPatterns of bullyingAnti-bullying interventionsYouth Risk Behavior Survey dataInfluence of alcoholTraditional bullyingBullying subgroupsWeapon-carryingDating violenceBehavior Survey dataAssociated with suicide attemptsBullyingReport bullyingMental healthPhysical fightingSelf-harmHigh school studentsCyberbullyingReceipt of social supportConnecticut high school studentsSurvey-weighted logistic regressionAcademic performanceLogistic regressionInsecure housingPerceived family support‘Am I really the priority here?’: help-seeking experiences of university students who self-harmed
Tickell A, Fonagy P, Hajdú K, Obradović S, Pilling S. ‘Am I really the priority here?’: help-seeking experiences of university students who self-harmed. BJPsych Open 2024, 10: e40. PMID: 38297500, PMCID: PMC10897682, DOI: 10.1192/bjo.2023.652.Peer-Reviewed Original ResearchSelf-harmMental health resourcesMental health servicesHelp-seeking journeyMental health problemsMental health issuesReflexive thematic analysisHelp-seeking behaviorUniversity studentsHelp-seeking experiencesSemi-structured interviewsPerceived facilitatorsSelf-harm tendenciesHealth servicesHealth resourcesProfessional helpThematic analysisEmotional distressHelp-seekingHealthcare systemHealth issuesStreamlined pathwayHealth problemsConcurrent fearPotential suicide
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