2025
Systematic Review and Meta‐Analysis of Dual‐Layered Stents Versus Single‐Layered Stents for Carotid Artery Stenosis
Mari T, Moeed A, Siddiqui A, Abbasi A, Arif Z, Jannat A, Akman Z, Rossi R, Unnar H, Bhatti H, Batool R, Khan M, Ali M, Batool F, Minahil, Iqbal J, Mena‐Hurtado C, Nanna M. Systematic Review and Meta‐Analysis of Dual‐Layered Stents Versus Single‐Layered Stents for Carotid Artery Stenosis. Catheterization And Cardiovascular Interventions 2025 PMID: 40518749, DOI: 10.1002/ccd.31684.Peer-Reviewed Original ResearchCarotid artery stentingCarotid artery stenosisSingle-layer stentsDual-layer stentsAll-cause mortalityPost-procedural strokeArtery stenosisRandomized controlled trialsStent occlusionHigher risk of peri-procedural strokePostprocedural strokeMeta-analysisRisk of peri-procedural strokeRisk ratioHigh riskCarotid artery stenting proceduresStroke riskPeri-procedural strokeRandom-effects meta-analysisPredictors of strokeTreat carotid artery stenosisLipid-rich carotid plaquesTreatment optionsArtery stentingPrimary outcomePublic Water Arsenic and Birth Outcomes in the Environmental Influences on Child Health Outcomes Cohort
Nigra A, Bloomquist T, Rajeev T, Burjak M, Casey J, Goin D, Herbstman J, Ornelas Van Horne Y, Wylie B, Cerna-Turoff I, Braun J, McArthur K, Karagas M, Ames J, Sherris A, Bulka C, Padula A, Howe C, Fry R, Eaves L, Breton C, Cassidy-Bushrow A, Lewis J, MacKenzie D, Beene D, Farzan S, Sathyanarayana S, Hipwell A, Morello-Frosch R, Snyder B, Hartert T, Elliott A, O’Connor T, Kress A, Smith P, Newby L, Adair L, Jacobson L, Catellier D, McGrath M, Douglas C, Duggal P, Knapp E, Kress A, Blackwell C, Mansolf M, Lai J, Ho E, Cella D, Gershon R, Macy M, Das S, Freedman J, Mallal S, McLean J, Shah R, Shilts M, Alshawabkeh A, Cordero J, Meeker J, Trasande L, Camargo C, Hasegawa K, Zhu Z, Sullivan A, Dabelea D, Perng W, Bekelman T, Wilkening G, Magzamen S, Moore B, Starling A, Rinehart D, Koinis Mitchell D, D'Sa V, Deoni S, Mueller H, Duarte C, Monk C, Canino G, Posner J, Murray T, Lugo-Candelas C, Dunlop A, Brennan P, Hockett C, Elliott A, Ferrara A, Croen L, Hedderson M, Ainsworth J, Bacharier L, Bendixsen C, Gern J, Gold D, Hartert T, Jackson D, Johnson C, Joseph C, Kattan M, Khurana Hershey G, Lemanske, Jr. R, Lynch S, Miller R, O’Connor G, Ober C, Ownby D, Rivera-Spoljaric K, Ryan P, Seroogy C, Singh A, Wood R, Zoratti E, Habre R, Farzan S, Gilliland F, Hertz-Picciotto I, Bennett D, Schweitzer J, Schmidt R, LaSalle J, Hipwell A, Karr C, Bush N, LeWinn K, Sathyanarayana S, Zhao Q, Tylavsky F, Carroll K, Loftus C, Leve L, Ganiban J, Neiderhiser J, Weiss S, Litonjua A, McEvoy C, Spindel E, Tepper R, Newschaffer C, Lyall K, Volk H, Landa R, Ozonoff S, Piven J, Hazlett H, Pandey J, Schultz R, Dager S, Botteron K, Messinger D, Stone W, Ames J, O'Connor T, Miller R, Oken E, Hacker M, James-Todd T, O'Shea T, Fry R, Frazier J, Singh R, Rollins C, Montgomery A, Vaidya R, Joseph R, Washburn L, Gogcu S, Bear K, Rollins J, Hooper S, Taylor G, Jackson W, Thompson A, Daniels J, Hernandez M, Lu K, Msall M, Lenski M, Obeid R, Pastyrnak S, Jensen E, Sakai C, Santos H, Kerver J, Paneth N, Barone C, Elliott M, Ruden D, Fussman C, Herbstman J, Margolis A, Schantz S, Geiger S, Aguiar A, Tabb K, Strakovsky R, Woodruff T, Morello-Frosch R, Padula A, Stanford J, Porucznik C, Giardino A, Wright R, Wright R, Collett B, Baumann-Blackmore N, Gangnon R, McKennan C, Wilson J, Altman M, Aschner J, Stroustrup A, Merhar S, Moore P, Pryhuber G, Hudak M, Reynolds Lyndaker A, Lampland A, Rochelson B, Jan S, Blitz M, Katzow M, Brown Z, Chiuzan C, Rafael T, Lewis D, Meirowitz N, Poindexter B, Gebretsadik T, Osmundson S, Straughen J, Eapen A, Cassidy-Bushrow A, Wegienka G, Sitarik A, Woodcroft K, Urquhart A, Levin A, Johnson-Hooper T, Davidson B, Ma T, Barrett E, Blaser M, Dominguez-Bello M, Horton D, Jimenez M, Rosen T, Palomares K, Avalos L, Zhu Y, Hunt K, Newman R, Bloom M, Alkis M, Roberts J, Mumford S, Burris H, DeMauro S, Yee L, Hamvas A, Olidipo A, Haddad A, Eiland L, Spillane N, Suri K, Fisher S, Goldstein J, Mithal L, DeRegnier R, Maitre N, Nguyen R, JaKa M, Sidebottom A, Paidas M, Potter J, Ruby N, Duthely L, Jayakumar A, Young K, Maldonado I, Miller M, Slaughter J, Keim S, Lynch C, Venkatesh K, Whitworth K, Symanski E, Northrup T, Mendez-Figueroa H, Mosquera R, Karagas M, Madan J, MacKenzie D, Lewis J, Rennie B, Leventhal B, Kim Y, Bishop S, Nozadi S, Luo L, Lester B, Marsit C, Everson T, Loncar C, McGowan E, Sheinkopf S, Carter B, Check J, Helderman J, Neal C, Smith L. Public Water Arsenic and Birth Outcomes in the Environmental Influences on Child Health Outcomes Cohort. JAMA Network Open 2025, 8: e2514084. PMID: 40522663, PMCID: PMC12171937, DOI: 10.1001/jamanetworkopen.2025.14084.Peer-Reviewed Original ResearchConceptsBirth weight-for-gestational age z-scoreLow birth weightAge z-scoreAdjusted risk ratiosAdverse birth outcomesBirth outcomesBirth weightMaximum contaminant levelWater arsenicWater arsenic exposureRisk ratioGestational agePreterm birthZ-scoreContamination levelsCohort studyAssociated with adverse birth outcomesHigher risk of low birth weightArsenic exposureParent-infant dyadsRisk of low birth weightUS Environmental Protection Agency maximum contaminant levelChild health outcomesAssociated with birth outcomesEnvironmental Protection Agency maximum contaminant levelSafety of Stimulants Across Patient Populations
Oliva H, Prudente T, Mayerson T, Mignosa M, Oliva I, Potenza M, Jegede O, Angarita G. Safety of Stimulants Across Patient Populations. JAMA Network Open 2025, 8: e259492. PMID: 40343695, PMCID: PMC12065045, DOI: 10.1001/jamanetworkopen.2025.9492.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderRandomized clinical trialsAdverse eventsStimulant medicationData extractionSafety of stimulationRisk ratioIncreased riskMethodological quality assessmentPreferred Reporting ItemsPatient populationClinical conditionsDiverse patient populationsRisk of biasSafety of stimulant medicationsUnclear risk of biasTreatment of attention-deficit/hyperactivity disorderOverall AEsRandom-effects modelWeb of ScienceBinge eating disorderStimulant use disorderComprehensive literature searchMain OutcomesReporting ItemsEfficacy of beta-blocker agents on clinical outcomes in patients with thoracic aortic aneurysm: A systematic review and meta-analysis of randomized controlled trials
Tanriverdi L, Barrett A, Kalyanasundaram A, Zafar M, Ziganshin B, Elefteriades J. Efficacy of beta-blocker agents on clinical outcomes in patients with thoracic aortic aneurysm: A systematic review and meta-analysis of randomized controlled trials. Vascular Pharmacology 2025, 159: 107494. PMID: 40204023, DOI: 10.1016/j.vph.2025.107494.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmRandomized controlled trialsPooled risk ratioB-blockersAortic dissectionClinical outcomesAortic aneurysmRisk ratioRisk of aortic dissectionMeta-analysis of randomized controlled trialsControlled trialsB-blocker treatmentCompared to placeboBeta-blocking agentsCochrane Risk of Bias 2 toolRisk of Bias 2 toolRobust randomized controlled trialsInverse variance-weighted random-effects modelRisk of bias assessmentRandom-effects modelEvidence of benefitSystematic literature searchAortic eventsEvidence-based recommendationsFollow-upOptical Coherence Tomography Versus Angiography Alone to Guide PCI for Complex Lesions: A Meta-Analysis of Randomized Controlled Trials
Ezenna C, Krishna M, Joseph M, Ibrahim S, Pereira V, Jenil-Franco A, Nanna M, Bangalore S, Goldsweig A. Optical Coherence Tomography Versus Angiography Alone to Guide PCI for Complex Lesions: A Meta-Analysis of Randomized Controlled Trials. Circulation Cardiovascular Interventions 2025, 18: e015141. PMID: 40159113, DOI: 10.1161/circinterventions.125.015141.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAdverse cardiovascular eventsRandomized controlled trialsOptical coherence tomographyMyocardial infarctionControlled trialsCardiac deathCardiovascular eventsComplex lesionsRisk ratioMeta-analysis of randomized controlled trialsOCT-guided percutaneous coronary interventionHigh-resolution intracoronary imagingMajor adverse cardiovascular eventsAssociated with lower major adverse cardiovascular eventsMedian follow-upTarget vessel revascularizationPeriprocedural myocardial infarctionRandom-effects modelClinical outcomesCoherence tomographyFollow-upCochrane DatabaseCoronary interventionStent thrombosisA96 WHICH IS THE BEST ENDOSCOPIC HEMOSTATIC THERAPY FOR DIEULAFOY’S LESIONS? A SYSTEMATIC REVIEW AND META-ANALYSIS
Samnani S, Yuan Y, Leontiadis G, Barkun A, Laine L, Tse F. A96 WHICH IS THE BEST ENDOSCOPIC HEMOSTATIC THERAPY FOR DIEULAFOY’S LESIONS? A SYSTEMATIC REVIEW AND META-ANALYSIS. Journal Of The Canadian Association Of Gastroenterology 2025, 8: i37-i37. PMCID: PMC11807509, DOI: 10.1093/jcag/gwae059.096.Peer-Reviewed Original ResearchEndoscopic band ligationOver-the-scope clipEndoscopic hemoclip placementTopical hemostatic agentsRandomized controlled trialsDieulafoy's lesionCohort studyRisk ratioHemostatic therapyEndoscopic therapyComposite outcome of failureControlled trialsMeta-analysesCochrane Central Register of Controlled TrialsEndoscopic hemostatic therapySignificant gastrointestinal bleedingCentral Register of Controlled TrialsPooled risk ratioComparative cohort studyRegister of Controlled TrialsTreatment of DLObservational cohort studyConfidence intervalsOver-the-scopeCochrane Central RegisterA43 TOPICAL HEMOSTATIC AGENTS: A POTENTIAL BREAKTHROUGH IN MALIGNANCY-RELATED GI BLEEDING? A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
Minhas G, Bukhari A, Yuan Y, Leontiadis G, Laine L, Barkun A, Tse F. A43 TOPICAL HEMOSTATIC AGENTS: A POTENTIAL BREAKTHROUGH IN MALIGNANCY-RELATED GI BLEEDING? A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. Journal Of The Canadian Association Of Gastroenterology 2025, 8: i17-i17. PMCID: PMC11807633, DOI: 10.1093/jcag/gwae059.043.Peer-Reviewed Original ResearchTopical hemostatic agentsGastrointestinal bleedingLength of hospitalizationEndoscopic techniquesNo significant differenceTC-325Blood transfusionComposite outcome of failureRisk ratioMeta-analysis of randomized controlled trialsCalculate pooled risk ratiosControlled trialsAverage length of hospitalizationCochrane Central Register of Controlled TrialsCentral Register of Controlled TrialsSignificant differencePooled risk ratioRegister of Controlled TrialsSystematic reviewCochrane Central RegisterConventional endoscopic methodsI 2 testCertainty of evidenceRandomized controlled trialsBleeding riskAmbient Toxic Air Contaminants in the Maternal Residential Area during Pregnancy and Cerebral Palsy in the Offspring
Zhuo H, Ritz B, Warren J, Pollitt K, Liew Z. Ambient Toxic Air Contaminants in the Maternal Residential Area during Pregnancy and Cerebral Palsy in the Offspring. Environmental Health Perspectives 2025, 133: 017008. PMID: 39853265, PMCID: PMC11758984, DOI: 10.1289/ehp14742.Peer-Reviewed Original ResearchConceptsToxic air contaminantsVolatile organic compoundsMaternal residential exposureCerebral palsyMixtures of volatile organic compoundsRisk of CPResidential exposureAir contaminationTraffic emission sourcesRisk factors of CPIncreased risk of CPRisk ratioCP casesEstimate mixture effectsResidential areasInterquartile range increaseConfidence intervalsLive singleton birthsModified Poisson regressionNegative control exposureQuantile-based g-computationFactors of CPCase-cohort studyContaminant mixturesEnvironmental risk factorsSex Differences in Long COVID
Shah D, Thaweethai T, Karlson E, Bonilla H, Horne B, Mullington J, Wisnivesky J, Hornig M, Shinnick D, Klein J, Erdmann N, Brosnahan S, Lee-Iannotti J, Metz T, Maughan C, Ofotokun I, Reeder H, Stiles L, Shaukat A, Hess R, Ashktorab H, Bartram L, Bassett I, Becker J, Brim H, Charney A, Chopra T, Clifton R, Deeks S, Erlandson K, Fierer D, Flaherman V, Fonseca V, Gander J, Hodder S, Jacoby V, Kotini-Shah P, Krishnan J, Kumar A, Levy B, Lieberman D, Lin J, Martin J, McComsey G, Moukabary T, Okumura M, Peluso M, Rosen C, Saade G, Shah P, Sherif Z, Taylor B, Tuttle K, Urdaneta A, Wallick J, Wiley Z, Zhang D, Horwitz L, Foulkes A, Singer N, Han J, Marconi V, Ofotokun I, Patzer R, Walker T, Abraham R, Aguilar F, Ahmadi-Izad G, Ahmed D, Alvarez A, Anderson B, Asencios W, Beaty C, Bedi B, Berry J, Boone D, Bower M, Bremner J, Brent C, Brown-Smith K, Bull R, Capo G, Carl-Igwe K, Chitadze C, Chukwumerije N, Clyburn E, Collins S, Costello J, Couture G, Craft A, Cui X, del Rio C, Detelich J, Dixon C, Dow J, Doyle D, Elchommali J, Elsey I, Franks N, Gallini J, Gutter E, Harding J, Hernandez L, Holloway C, Ifejika C, Jasarevic R, Javia V, Jeter M, Joseph Y, Juarez M, Kirkpatrick C, Koumanelis A, Krishnan S, Leon J, Lew V, Maier C, Makkaoui N, Maroney M, Martin C, Mbogo L, McCaslin A, McIntyre J, Moanna A, Montoya M, Morales E, Moran C, Murray C, Nelson R, Nguyen T, Ojoawo B, Osinski E, Oviedo S, Paredes-Gaitan Y, Prude M, Ramakrishnan G, Rebolledo P, Roberts M, Robinson K, Rogers C, Rouphael N, Searles C, Segall M, Shah A, Silva R, Simpson C, Simpson-Derrell K, Sirajud-Deen T, Stroud J, Suthar M, Sylber C, Sylvera A, Teunis L, Thomas K, Titanji K, Toy C, Truong A, Vaccarino V, Varney K, Vyas K, Vyas K, Walkow M, Wesley T, Winston J, Winter T, Wongtrakool C, Cribbs S, Francis A, Hang T, Ingram K, Lainez J, Wiley Z, Ager A, Atha M, Gray N, Grimes A, Hewitt L, Huerta C, Johnson B, Khalil L, Kleinhenz D, Koumanelis A, Kozoman R, Lee M, Lewis K, Litvack M, Maramba T, Mehta C, Panganiban B, Rahman K, Smith V, Stringer A, Tolbert M, Traenkner J, Unterberger K, Wang H, Wimberly E, Yang Q, Gander J, Neuman R, Bush P, Hudgins A, Kolailat I, Martinez M, Thompson S, Agu C, Pemu P, Afani A, Ariri C, Dandy A, Harper K, Ibeawuchi C, Lawrence B, Morgan-Billingslea J, Ojemakinde E, Smith K, Levy B, Aikawa M, Baden L, Baslet G, Bennett L, Bhattacharyya S, Buring J, Cagnina R, Chen L, Clark C, Cohen P, Czeisler C, Estill P, Gay E, Hong J, Lamas D, Lay S, Levy-Carrick N, Manson J, Monafrared T, Redline S, Remis E, Schilkrut D, Sesso H, Solomon S, Sparks J, Spencer L, Systrom D, Thu P, Walt D, Washko G, Whittelsey M, Wiener R, Bassett I, Alba G, Aung T, Ginns L, Haas J, Hu Y, Juelg B, Kanjilal D, Kim A, Klerman E, Lewis G, Musa A, Ojikutu B, Perlis R, Rosand J, Wallace Z, Xerras D, Zionts D, Mullington J, Collier A, Fong T, Haack M, Hauser K, Maley J, Quintana Y, Shaughnessy L, Stephenson K, Thomas R, Torres R, Marathe J, Duffy E, Hamburg N, Kobayashi M, O'Connor G, Shepherd F, Williams C, Zhang H, John J, Ticotsky A, Ward H, Blazey-Martin D, Ghamloush M, Jordan M, Kogelman L, Erdmann N, Levitan E, Tita A, Armstrong D, Binkley S, Blackwell K, Causey A, Cook F, Domingo J, Donahue C, Eady M, Edberg J, Forehand K, Frazier P, Garcia-McClaney N, Garner M, Gray B, Hall W, Hart C, Hebson C, Hidalgo B, Holtzapfel K, Jinright A, Judd S, Kennedy T, Kirkwood L, Maier M, McCormack P, Mitchell K, Montgomery A, Peralta-Carcelen M, Pilco J, Powell L, Royster J, Shevin R, Skipworth S, Spurgeon L, Steele C, Vines J, Ware G, Wilson R, Woodruff D, Young B, Gillespie M, Daniel C, Hansel J, Wu J, Carton T, Miele L, Brown T, Sutherland E, Fuloria J, Datri P, Hagensee M, Leggio C, Perkins A, Trauth A, Trotter S, Van Deerlin A, Weiser S, Young M, Ashktorab H, Brim H, Laiyemo A, Sherif Z, Durrani S, Nezamloo A, Ngwa J, Njoku N, Gentil M, Mehari A, Solemani A, Chang L, Thuluvath P, Alemu M, Anderson J, Chauhan M, Cho S, Goodman K, Lanke G, Lebron R, Maheshwari A, Ok J, To C, Hodder S, Bardes J, Dominique-Villanueva D, Juskowich J, Reece R, Sarwari A, Shellito J, Greenway F, Kirwan J, Rodemann G, Rosen C, Arruda A, Brunet T, Emery I, Roelke T, Berger P, Hoover S, Black L, Tjarks B, Fonseca V, Gupta S, Longo M, Yang M, Shikuma C, Chow D, MarGangcuangco L, Castro M, Bengtson C, Howard T, Koontz B, Spikes L, Simmons C, Whiteheart S, Garvy B, Wood J, Marshall G, Garla V, Kuebler J, Nandi U, Vasey A, Warren D, Dickinson J, VanWagoner T, Bogie A, Heyanka D, James J, Scott J, Sukhera F, Luciano Roman C, Perez Frontera S, Santana Bagur J, Klein J, Krishnan J, Lin J, Muramatsu N, Prabhakar B, Prendergast H, Vanden Hoek T, Adams D, Baker A, Barbera S, Basu S, Bleasdale S, Boyd A, Breiter T, Buhimschi I, Carrithers M, Chalamalla R, Chestek D, Cook J, Darbar D, Dasgupta R, Davis Blakley F, DeLisa J, Diviak K, Donlon M, Dworkin M, Ellison A, Flanigan C, Freedman M, Gerald L, Giles W, Gordon H, Hammad B, Hasek S, Hasse W, Hryniewicka M, Illendula S, Ismail N, Jain A, Jennette K, Kadubek G, Kent D, Kent D, Kim K, Kotini-Shah P, Large L, Lash J, Lu J, Mahamed A, Malchenko S, Martinez M, Mauntel-Medici C, McCauley M, Menchaca M, Mermelstein R, Moreno D, Morrissy L, Musick H, Norwick L, Novak R, Ortiz M, Patel K, Perez N, Pliskin N, Pope S, Prasad B, Predki B, Quigley J, Ramchandran R, Ramirez A, Rappe S, Rehman J, Rowley M, Rudraraju G, Rutherfoord M, Sculley J, Smith-Mack J, Sun J, Tartt N, Villanueva L, Warfield Kelly S, Yazici C, Certa M, Chessier E, Everett E, Kindred E, Harris P, Sudhindra P, Olds L, Aponte-Soto L, Del Rios M, Diaz M, Ibanez A, Rolon C, Cranford S, Brown D, Dixon J, Gale L, Hammerl S, Hartwig K, Madineni A, Swearingen P, Hendrickson M, Noland S, Terlinde T, Hobbs B, Stewart de Ramirez S, Bolliger D, Boyineni J, Chebrolu P, Curry H, Donohue S, Edmonds S, Kelly S, Maholovich P, Sader S, Thompson T, Welter H, Woolley B, Hafner J, Hanson K, Hutton R, Charney A, Kovatch P, Merad M, Nadkarni G, Wisnivesky J, Aberg J, Ascolillo S, Bagiella E, Bartram L, Becker J, Beckmann N, Bendl A, Chen B, Civil A, Crawford G, Dhar K, Evo-Ortega L, Fierer D, Gallagher E, Garcia-Sastre A, Gnjatic S, Gray I, Guliyeva S, Harvey-Ingram L, Herrera-Moreno J, Hill M, Horowitz C, Jackson R, Kastrat D, Lala-Trindade A, Lin J, Macaluso N, Marcon K, Meyer D, Morinigo J, Natelson B, Nussenzweig M, Padua T, Putrino D, Richardson L, Russo S, Seifert A, Serri A, Walker J, Yee M, Bateman L, Hess R, Truong D, Alekhina N, Barlocker J, Brown J, Cortez M, Donohue D, Facelli J, Ford I, Gouripeddi R, Hermansen J, Johnny J, Lindsay A, Ling L, Lloyd J, Lu Y, Medina J, Morimoto S, Pace L, Powell J, Scholand M, Shah K, Sharareh N, Spivak A, Stringham C, Trinity J, Velinder M, Weaver L, Vernon S, Deakyne Davies S, Gardner E, Bryan T, Buck K, Hawkins K, Oakes J, Horne B, Knowlton K, Woller S, Aguirre B, Anderson J, Bair T, Bosh L, Evans L, Garrett C, Harris D, Herrera K, Iverson L, Jensen M, Juan J, Knight S, Leither L, Maestas H, May H, Najarian G, Webb T, Zubal S, Erlandson K, Sokol R, Brightman M, Davis D, Feuerriegel E, Fudge H, Garg L, Higgins J, Jolley S, Lockie T, McCandless S, Pitch C, Reusch J, Thurman B, Tran H, West S, Friedman N, Ludwig K, Decker L, Raissy H, Adolphi N, Archuleta D, Bradfute S, Brito R, Elifritz J, Garcia-Soberanez N, Gentry F, Harkins M, Martinez N, Montoya L, Parada A, Quinn D, Ramos A, Sheehan E, Treacher I, McComsey G, Adams C, Andrefsky J, Atieh O, Baissary J, Boldt N, Conrad A, D’Anza B, Koberssy Z, Daher J, Dawson S, DiFrancesco K, Durieux J, Foster (Rodgers) T, Gallagher M, Gupta A, Harrill J, Harris P, Hernandez C, Ialacci S, Jacono F, Kelly J, Kumar R, Labbato D, Lesco E, Lim J, Pettinato K, Rodgers M, Rosolia B, Roy A, Scott S, Smith B, Tejani V, Tribout M, Yendewa G, Zhang D, Singer N, Ayache M, Barnboym E, Brown A, Chesnick H, Edminston M, Greenwood C, Haghiac M, Kaufman E, Lengu K, Lowenthal R, Malakooti S, Oleson C, Pearman A, Rizea A, Smith C, Washington M, Weinberger E, Heath J, Brennan C, Edmark R, Gutierrez V, Hadlock J, Li S, Magis A, McDonald C, Murray K, Rowen L, Yuan D, Chen P, Caudill A, Chopra T, Contreras F, Dahlke L, Gudipudi L, Jackman S, Modes M, Muttera N, Nelson C, Parimon T, Salinas N, Tadeo J, Torbati S, Watson S, Tuttle K, Alicic R, Baxter J, Emerson S, Hood S, Kuykendall K, White S, Wilcox L, Goldman J, Algren H, Del Alcazar J, Duven A, Kaneko J, Kim C, Manner P, Mason C, Okada A, Poussier R, Satira R, Wallick J, Chu H, Elias-Warren A, Harteloo A, Logue J, McCaffrey K, Nguyen H, Nambiar A, Patterson T, Potter J, Salehi M, Sharma K, Verduzco-Gutierrez M, Anderson R, Arellanes A, Barajas R, Chauhan S, Clarke G, Farner C, Fischer M, Goldberg M, Hastings G, Heard P, Hernandez J, Herrera I, Infante E, Johnson H, Jones J, Kellogg D, Kraig E, Longoria L, Okafor E, Patterson J, Pinones A, Reeves W, Scholler I, Seshadri S, Shah P, Shah D, Smith M, Soileau B, Solis P, Stoebner C, Sullivan M, Taylor B, Tragus R, Tsevat J, Hasbani K, Saade G, Sharma K, Paredes C, Alvarado S, Kumar A, Maldonado Y, Utz P, Blish C, Go M, Jagannathan P, Singh U, Ahuja N, Blomkalns A, Bonilla H, Brotherton R, Clinton K, Dingankar V, Geng L, Haddad F, Jamero C, Jee K, Jia X, Khurana N, Miglis M, O'Conor E, Olszewski K, Pathak D, Quintero O, Saperia C, Scott J, Urdaneta A, Varkey M, Nikolich J, Parthasarathy S, Ernst K, Esquivel D, Harris D, Harris S, Hernandez M, Hsu H, James M, Karnafel M, Knox K, Koleski A, LaFleur B, Lambert B, LaRue S, Lutrick K, Merchant N, Morton C, Mosier J, Olorunnisola T, Peralta J, Pilling W, Pogreba-Brown K, Rischard F, Ryan L, Smith T, Snyder M, Subbian V, Suhr K, Velarde D, Reiman E, Lee-Iannotti J, Autry L, Beydoun H, Borwege S, Copeland J, DiLise-Russo M, Fadden S, Gomez I, Grischo G, Hartley W, Hillier L, Ismail H, Iusim S, Kala M, Kim D, Murthy G, Unzek S, Vadovicky S, Veres S, Bime C, Hansen L, Hughes T, Lieberman D, Soto F, Wilson C, Zapien A, Deeks S, Kelly J, Martin J, Peluso M, Anderson G, Anglin K, Argueta U, Asare K, Buitrago M, Chang Song C, Clark A, Conway E, Del Castillo N, Deswal M, Durstenfeld M, Eilkhani E, Eun A, Fehrman E, Figueroa T, Flores D, Grebe H, Henrich T, Hoh R, Hsue P, Huang B, Ibrahim R, Kerbleski M, Kirtikar R, Lew M, Lombardo J, Lopez M, Luna M, Marquez C, Munter S, Ngo L, Pineda-Ramirez J, Prather A, Rhoads K, Rodriguez A, Romero J, Ryder D, So M, Somsouk M, Tai V, Tran B, Uy J, Valdivieso D, Verma D, Williams M, Zamora A, Newman L, Abella J, Barnette Q, Bevc C, Beverly J, Ceger P, Croxford J, Cunningham E, Enger M, Fain K, Farris T, Hanlon S, Hines D, Johnson-Lawrence V, Jordan K, Lefebvre C, Linas B, Luukinen B, Mandal M, McKoy N, Nance S, Oakland A, Pasquarelli D, Quiner C, Sembajwe R, Shaw G, Thornburg V, Tosco K, Wright H, Gross R, Hochman J, Horwitz L, Katz S, Troxel A, Adler L, Akinbo P, Almenana R, Bello O, Bhuiyan S, Blachman N, Branski R, Briscoe J, Brosnahan S, Bueler E, Burgos Y, Caplin N, Chaplin D, Chen Y, Cheng S, Choe P, Choi J, Chung A, Church R, Cobos S, Croft N, Cruz Irving A, Del Boccio P, Díaz I, Doshi V, Dreyer B, Ebel S, Faustin A, Febres E, Fine J, Fink S, Frontera J, Gallagher R, Gonzalez-Duarte A, Hasson D, Hill S, Islam S, Johnson S, Kansal N, Kenney R, Kewlani D, Lamendola-Essel M, Laynor G, Leon T, Lewczak Z, Linton J, Logan M, Malik N, Mamistvalova L, Mandel H, Maranga G, Mathews P, Mattoo A, Mei T, Mendelsohn A, Mercier E, Millar Vernetti P, Miller M, Mitchell M, Moreira A, Mudumbi P, Nahin E, Nair N, Nekulak J, Owens K, Parent B, Patibandla N, Petrov P, Postelnicu R, Randall I, Rao P, Rapkiewicz A, Rizzo J, Rosas J, Rose C, Saint-Jean C, Santacatterina M, Shah B, Shaukat A, Simon N, Simsir A, Stinson M, Tang W, Tatapudi V, Thawani S, Thomas M, Thorpe L, Tom M, Treiha E, Truong J, Udosen M, Velazquez-Perez J, Vernetti P, Vidal C, Viswanathan A, Wong C, Wood M, Wuller S, Yin S, Young C, Zaretsky J, Zavlunova S, Foulkes A, Karlson E, Murphy S, Ahirwar S, Ahmed S, Ainsworth L, Atchley-Challenner R, Avilach P, Balan T, Benik N, Benoit B, Bind M, Bonaventura W, Boutin N, Brion B, Cagan A, Cai T, Cao T, Castro V, Cerretani X, Chan J, Cheng D, Chibnik L, Ciriello M, Costenbader K, Dimitrov D, Estiri H, Fayad M, Feldman C, Gainer V, Ghosh B, Gollub R, Guan Z, Harris A, Helmer K, Hendrix A, Holzbach A, Huang W, Kaufman D, Keogh D, Kerr J, Klann J, Krishnamoorthy A, Lasky-Su J, Liao K, MacFadden D, Maram A, Martel M, Mendis M, Metta R, Monteiro J, Morales E, Morse R, Nazaire M, Neils G, Nguyen A, Norman J, Paik H, Pant D, Park H, Rabideau D, Reeder H, Rossi-Roh K, Santacroce L, Schlepphorst K, Schulte C, Selvaggi C, Shinnick D, Simons W, Simpson L, St. Jean Flanders M, Strasser Z, Thakrar M, Thaweethai T, Thorn M, Trewett P, Van Fleet D, Wagholikar K, Wang T, Wattanasin N, Weber G, Williams M, Zhang R, Cerda M, Clash V, Taylor B, Zissis M, Akintonwa T, Blancero F, Brown H, Carmilani M, Copeland D, Hall Y, kondo K, Lerma L, Lindsay J, Marti H, Maughan C, Minor T, Vincent H, Burns J, Spudich S, Bailey C, Cicek M, Cortez M, Foulkes A, Goff D, Lasky-Su J, Metz T, Ofotokun I, Stockwell M, Stone J, Taylor B, Utz P, Williams N, Anderson B, Bardhan S, Castro-Baucom L, Chisolm D, Corchado C, Dehority W, Dinwiddie G, Goldman Rosas L, Thomas G, Lopez K, MacDonald Pinkett S, Regino L, Valencia C, Vangeepuram N, Walden A, Burton P, Catallozzi M, Dworetzky B, Edwards B, Ferrer R, Freeland C, Laury S, Pearson G, Rothman R, Wagner L, Wallace A, Aragon L, Bander B, Bishof K, Carignan E, Castro Baucom L, Clash V, Coombs K, Corchado C, Davis H, Diggs M, Dunn M, Fisher L, Fitzgerald M, Gage Witvliet M, Gustafson T, Holmes V, Hornig M, Hornig M, Jain N, Lam J, Letts R, Lewis J, Martinez T, McCorkell L, McGrath R, Nguyen K, Nichols L, O'Brien L, Peddie A, Perlowski A, Phillips-Lorenzo E, Prentiss L, Raytselis N, Rockwell M, Rutter J, Seibert E, Sekar A, Taylor E, Wilensky R, Williams M, Williams N, Williams-Dawson K, Wylam A. Sex Differences in Long COVID. JAMA Network Open 2025, 8: e2455430. PMID: 39841477, PMCID: PMC11755195, DOI: 10.1001/jamanetworkopen.2024.55430.Peer-Reviewed Original ResearchConceptsRisk of long COVIDRisk ratioFemale sexSocial determinants of healthCohort studyManagement of long COVIDLong COVIDDeterminants of healthFemale participantsSymptom-based questionnaireEstimate risk ratiosProspective cohort studyAssociated with higher riskStates plus WashingtonNational Institutes of Health (NIHSocial determinantsSelf-reported sexEvaluate sex differencesMain OutcomesPost-COVID conditionsNonpregnant participantsRisk differenceMale participantsMenopausal statusCOVID risk
2024
Impact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysis
Rassi A, Grimshaw A, Sarwal A, Sah R, Shah S, Agudelo Higuita N, Rassi F, Corbisiero M, Kyllo H, Stellern J, Kaplan S, Marcos L, Ramírez-García E, Casapia M, Hotez P, Bottazzi M, Patel S, Franco-Paredes C, Marin-Neto J, Henao-Martínez A. Impact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysis. EClinicalMedicine 2024, 79: 102972. PMID: 39810938, PMCID: PMC11732499, DOI: 10.1016/j.eclinm.2024.102972.Peer-Reviewed Original ResearchChronic Chagas diseaseMethodological quality of studiesCardiovascular deathQuality of studiesDisease progressionQuality of evidenceVirtual Health Library databasesRisk of bias scaleCardiovascular outcomesRandom-effects modelPooled risk ratioMeta-analysis of studiesMethodological qualityWeb of Science Core CollectionAntitrypanosomal therapyRandomized controlled studyManagement of Chagas diseaseOvid MEDLINESystematic reviewInclusion criteriaMeta-analysesRisk ratioScience Core CollectionPrimary outcomeOvid EmbaseFractional flow reserve-guided complete revascularization versus culprit-only percutaneous coronary intervention in patients with myocardial infarction: A meta-analysis of randomized controlled trials
Ezenna C, Krishna M, Joseph M, Pereira V, Ramesh P, Ismayl M, Nanna M, Goldsweig A. Fractional flow reserve-guided complete revascularization versus culprit-only percutaneous coronary intervention in patients with myocardial infarction: A meta-analysis of randomized controlled trials. Cardiovascular Revascularization Medicine 2024 PMID: 39721936, DOI: 10.1016/j.carrev.2024.12.004.Peer-Reviewed Original ResearchContrast-induced acute kidney injuryMultivessel coronary artery diseaseFFR-guided CRCoronary artery diseaseComposite adverse eventsPercutaneous coronary interventionRandomized controlled trialsCardiac deathAdverse eventsMyocardial infarctionComplete revascularizationRecurrent myocardial infarction ratesMedian follow-up durationRisk ratioCoronary interventionStent thrombosisMeta-analysis of randomized controlled trialsControlled trialsFFR-guided complete revascularizationFollow-up durationMeta-analysisAcute kidney injuryAll-cause deathCochrane Central databasesCulprit-only percutaneous coronary interventionAssociations Between Patient Characteristics and Progression to Multiple Myeloma Among Patients With Monoclonal Gammopathy of Undetermined Significance: A Systematic Review
Li Y, Hsu S, Wang R, Theprungsirikul P, Neparidze N, Chang S, Wang S. Associations Between Patient Characteristics and Progression to Multiple Myeloma Among Patients With Monoclonal Gammopathy of Undetermined Significance: A Systematic Review. Clinical Lymphoma Myeloma & Leukemia 2024, 25: e222-e231. PMID: 39730300, PMCID: PMC11911095, DOI: 10.1016/j.clml.2024.12.006.Peer-Reviewed Original ResearchProgression to MMMultiple myelomaNewcastle-Ottawa ScaleMonoclonal gammopathyRisk of progression to MMIncreased riskProgression to multiple myelomaRisk estimatesHigher body mass indexPre-malignant conditionBody mass indexRandom-effects modelMass indexCohort studyPatient characteristicsFemale sexMale genderMethodological qualityNewcastle-OttawaBlack raceRisk ratioMGUSRisk factorsPublication biasSystematic reviewEffects of ambient temperature on mental and neurological conditions in older adults: A systematic review and meta-analysis
Byun G, Choi Y, Foo D, Stewart R, Song Y, Son J, Heo S, Ning X, Clark C, Kim H, Choi H, Kim S, Kim S, Burrows K, Lee J, Deziel N, Bell M. Effects of ambient temperature on mental and neurological conditions in older adults: A systematic review and meta-analysis. Environment International 2024, 194: 109166. PMID: 39603080, PMCID: PMC11675999, DOI: 10.1016/j.envint.2024.109166.Peer-Reviewed Original ResearchOlder adultsWorld Health OrganizationHealth of older adultsStudy designNeurological conditionsSystematic reviewMental disordersRisk ratioEpidemiological evidenceAmbient temperature exposureCase-crossover analysisRandom-effects meta-analysesExposure metricsOlder adult populationIncreased riskMeta-analysisPooled effect estimatesRisk of biasCertainty of evidencePeer-reviewed journal articlesPooled risk ratioWeb of ScienceHealth outcomesScreened articlesModerate certaintyEfficacy of beta blockers in patients with thoracic aortic aneurysm: meta-analysis of randomized controlled trials
Tanriverdi L, Barrett A, Kalyanasundaram A, Zafar M, Ziganshin B, Elefteriades J. Efficacy of beta blockers in patients with thoracic aortic aneurysm: meta-analysis of randomized controlled trials. European Heart Journal 2024, 45: ehae666.2256. DOI: 10.1093/eurheartj/ehae666.2256.Peer-Reviewed Original ResearchThoracic aortic aneurysmRandomized controlled trialsPooled risk ratioB-blockersAortic aneurysmAortic dissectionControlled trialsAortic eventsRisk ratioPrimary outcomePooled risk estimatesRisk of aortic dissectionRisk of bias assessmentNo treatmentMeta-analysis of randomized controlled trialsInverse variance-weighted random-effects modelMeta-analysisLiterature searchB-blocker treatmentSystematic review protocolInternational Prospective RegisterCochrane Central Register of Controlled TrialsEfficacy of beta blockersCentral Register of Controlled TrialsSummary effect measuresChiropractic Spinal Manipulation and Fall Risk in Older Adults With Spinal Pain: Observational Findings From a Matched Retrospective Cohort Study
Trager R, Burton W, Loewenthal J, Perez J, Lisi A, Kowalski M, Wayne P. Chiropractic Spinal Manipulation and Fall Risk in Older Adults With Spinal Pain: Observational Findings From a Matched Retrospective Cohort Study. Cureus 2024, 16: e72330. PMID: 39583476, PMCID: PMC11585376, DOI: 10.7759/cureus.72330.Peer-Reviewed Original ResearchSpinal manipulative therapyNegative control outcomesSpinal painFall riskRisk ratioOlder adultsLimb fracturesChiropractic spinal manipulative therapyCumulative incidence of fallsChiropractic spinal manipulationFall risk factorsReducing fall riskIncidence of fallsAssociated with fallsControl outcomesRandomized controlled trialsSpinal manipulationManipulative therapyInjurious fallsCumulative incidenceCare utilizationRetrospective cohort studyFracture incidenceCohort studyControlled trialsHypo-Albuminemia and Perioperative Renal Transplant-Related Infections: A Systematic Review and Meta-Analysis
Mohammadi A, Inanloo S, Rezaeian A, Menbari Oskouie I, Khajavi A, Mirzaei A, Ahmadi Pishkuhi M, Oliveira Reis L, Aghamir S. Hypo-Albuminemia and Perioperative Renal Transplant-Related Infections: A Systematic Review and Meta-Analysis. Urology Journal 2024, 21: 7943-7943. PMID: 38734965, DOI: 10.22037/uj.v21i.7943.Peer-Reviewed Original ResearchType of infectionRisk ratioDerSimonian-Laird random-effects modelTransplant-related infectionsPost-transplantation infectionsPost-transplant surveillanceSystematic reviewMeta-analysesStata version 17Preferred Reporting ItemsRandom-effects modelRenal transplantationMeasures of associationPretransplant screeningAlbumin levelsHypo-albuminemiaImpact of infectionAdult patientsWeb of ScienceHazard ratioOdds ratioViral typesViral infectionReporting ItemsInfectionCombined interventions for the testing and treatment of HIV and schistosomiasis among fishermen in Malawi: a three-arm, cluster-randomised trial
Choko A, Dovel K, Kayuni S, Conserve D, Buttterworth A, Bustinduy A, Stothard J, Kamchedzera W, Mukoka-Thindwa M, Jafali J, MacPherson P, Fielding K, Desmond N, Corbett E. Combined interventions for the testing and treatment of HIV and schistosomiasis among fishermen in Malawi: a three-arm, cluster-randomised trial. The Lancet Global Health 2024, 12: e1673-e1683. PMID: 39304239, PMCID: PMC11420466, DOI: 10.1016/s2214-109x(24)00283-3.Peer-Reviewed Original ResearchConceptsVoluntary male medical circumcisionHIV self-test kitsCluster randomised trialSelf-test kitsPeer educatorsDistribution of HIV self-testing kitsIncrease uptake of ARTSOC groupUptake of antiretroviral therapyThree-armEnhanced standard of careAntiretroviral therapyRisk ratioNational Institute for Health ResearchHard-to-reach communitiesMale medical circumcisionUK National Institute for Health ResearchStandard of careProportion of participantsIntracluster correlation coefficientPE groupComputer-generated random numbersActive schistosomiasisUndiagnosed HIVAntiretroviral therapy initiationIntravascular imaging-guided vs. angiography-guided percutaneous coronary intervention: A systematic review and meta-analysis of randomized controlled trials in high-risk patients and complex coronary anatomies
Teixeira L, Ferreira R, Navalha D, Pasqualotto E, Fae I, Gibicoski T, Chavez M, Talavera A, Athayde G, Chamie D. Intravascular imaging-guided vs. angiography-guided percutaneous coronary intervention: A systematic review and meta-analysis of randomized controlled trials in high-risk patients and complex coronary anatomies. International Journal Of Cardiology 2024, 416: 132510. PMID: 39222885, DOI: 10.1016/j.ijcard.2024.132510.Peer-Reviewed Original ResearchConceptsHigh-risk patientsPercutaneous coronary interventionMeta-analysis of randomized controlled trialsRandomized controlled trialsTarget vessel failureComplex coronary anatomyCoronary anatomyComplex lesionsRisk ratioCardiovascular mortalityStent thrombosisMyocardial infarctionControlled trialsAngiography-guided percutaneous coronary interventionProcedure-related complicationsMeta-analysisRisk of MACEAdverse cardiac eventsConfidence intervalsSystematic reviewIntravascular imagingRandom-effects modelNo significant differenceCardiac eventsPrimary outcomeDisability severity and risk of new or recurrent intimate partner violence – Evidence from a cohort study in rural Pakistan
Collins A, Maselko J, Hagaman A, Bates L, Haight S, Kachoria A, Gupta S, Bhalotra S, Sikander S, Bibi A. Disability severity and risk of new or recurrent intimate partner violence – Evidence from a cohort study in rural Pakistan. Disability And Health Journal 2024, 18: 101673. PMID: 39095292, PMCID: PMC11625620, DOI: 10.1016/j.dhjo.2024.101673.Peer-Reviewed Original ResearchSexual intimate partner violenceRisk ratioIntimate partner violenceDisability severityModified Poisson regression modelsRural PakistanPoisson regression modelsCohort of mothersSouth Asian contextDisability levelLow-incomeCohort studyPhysical intimate partner violencePsychological intimate partner violenceDisabilityAsian contextConsecutive wavesRegression modelsPartner violenceMothersRiskCohortCultural normsCross-sectionLow severityPositive Associations of Perfluoroalkyl and Polyfluoroalkyl Substances With Hypertension May Be Attenuated by Endogenous Sex Hormones: A Nationally Representative Cross-Sectional Study
Wu B, Sheng N, Li Z, Wang J, Ji S, Zhao F, Pan Y, Qu Y, Wei Y, Xie L, Li Y, Hu X, Wu C, Zhang Z, Qiu Y, Zheng X, Zhang W, Hu X, Song H, Cai J, Cao Z, Ji J, Lv Y, Dai J, Shi X. Positive Associations of Perfluoroalkyl and Polyfluoroalkyl Substances With Hypertension May Be Attenuated by Endogenous Sex Hormones: A Nationally Representative Cross-Sectional Study. Hypertension 2024, 81: 1799-1810. PMID: 38853753, DOI: 10.1161/hypertensionaha.123.22127.Peer-Reviewed Original ResearchDiastolic blood pressureSystolic blood pressureEndogenous sex hormonesBlood pressureNationally representative cross-sectional studyPositive associationPerfluoroheptane sulfonic acidWeighted multiple logistic regressionSex hormonesLevels of endogenous sex hormonesPrevalence of hypertensionCross-sectional studyMultiple logistic regressionAssociations of polyfluoroalkyl substancesPFAS mixtureJoint effects of PFAS mixtureAssociated with hypertensionProgression of hypertensionChinese adultsSynergy indexOdds ratioG-computationQuantile-based g-computationRisk ratioLogistic regression
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