2025
Does intimate partner violence mediate the association between adverse childhood experiences and internalizing symptomatology in women? A mediation meta-analysis
Martini J, Deneault A, Zhu J, Racine N, Fearon P, Madigan S, Jenkins J. Does intimate partner violence mediate the association between adverse childhood experiences and internalizing symptomatology in women? A mediation meta-analysis. Journal Of Affective Disorders 2025, 119742. PMID: 40550278, DOI: 10.1016/j.jad.2025.119742.Peer-Reviewed Original ResearchAdverse childhood experiencesInternalizing symptomatologyIntimate partner violenceTest moderationAssociated with internalizing symptomatologyChildhood experiencesAdverse childhood experience itemsPartner violenceMeta-analyticallySymptomatologyStructural equation modeling approachMethodological factorsIndirect pathwaysEffect sizePath modelFemale participantsStructural equationModeratelyPsychopathologySociodemographic factorsViolenceAssociationMASEMItemsAge of female participantsRandomized Controlled Trial of Weight Management Versus Weight Management With Concurrent Cognitive‐Behavioral Therapy for Binge‐Eating Disorder in US Veterans With High Weight
Masheb R, Buta E, Snow J, Munro L, Lawless M, Abel E, McWain N, Marsh A, Cary A, Grilo C, Raffa S, Ruser C. Randomized Controlled Trial of Weight Management Versus Weight Management With Concurrent Cognitive‐Behavioral Therapy for Binge‐Eating Disorder in US Veterans With High Weight. International Journal Of Eating Disorders 2025 PMID: 40485646, DOI: 10.1002/eat.24476.Peer-Reviewed Original ResearchDSM-5 binge-eating disorderBinge-eating disorderDSM-5Cognitive-behavioral therapyEating-disorder treatmentRemission rateUS military veteransBinge-eating frequencyMilitary veteransCBTVeteran populationShape-relatedVeteransWeight managementPost-treatmentWeight management programUS veteransMixed-effects modelsDisordersRandomized controlled trialsClinical Trials Registry numberPsychopathologyBinge-eatingWeight lossClinical guidanceIs there harm in behavioral lifestyle weight management for binge-eating disorder in patients with obesity: Findings from a randomized controlled trial
Grilo C, Ivezaj V, Yurkow S, Lydecker J. Is there harm in behavioral lifestyle weight management for binge-eating disorder in patients with obesity: Findings from a randomized controlled trial. Journal Of Psychosomatic Research 2025, 195: 112169. PMID: 40516275, DOI: 10.1016/j.jpsychores.2025.112169.Peer-Reviewed Original ResearchEating-disorder psychopathologyBinge-eating disorderIncreased symptomsSymptoms of binge eatingRandomized controlled trialsBinge-eating frequencyBinge eatingPsychopathologyRandomized to placeboBinge-eatingWeight managementPlaceboHeterogeneity of outcomesDisordersParticipantsPosttreatmentSecondary analysisFrequency of casesSymptomsClinical contextIndividual levelObesityControlled trialsSmall magnitudePatientsIntegrating HiTOP and RDoC frameworks Part I: Genetic architecture of externalizing and internalizing psychopathology
Davis C, Khan Y, Toikumo S, Jinwala Z, Boomsma D, Levey D, Gelernter J, Kember R, Kranzler H. Integrating HiTOP and RDoC frameworks Part I: Genetic architecture of externalizing and internalizing psychopathology. Psychological Medicine 2025, 55: e138. PMID: 40336358, PMCID: PMC12094639, DOI: 10.1017/s0033291725000856.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesMultivariate genome-wide association studyGenetic architectureComorbid forms of psychopathologyHierarchical Taxonomy of PsychopathologyBivariate causal mixture modelResearch Domain CriteriaTaxonomy of PsychopathologyPsychiatric classification systemsConfirmatory factor modelsInternalizing psychopathologyComorbid formsGenetic liabilityPsychopathologyTwo-factorHierarchical taxonomyModerate genetic correlationLatent factorsAssociation studiesBiological basisHiTOPReference panelGenetic underpinningsFactor modelGenetic variantsLifestyle behavioral weight‐loss treatment for binge‐eating disorder in patients with obesity: where's the harm?
Yurkow S, Ivezaj V, Grilo C. Lifestyle behavioral weight‐loss treatment for binge‐eating disorder in patients with obesity: where's the harm? Obesity 2025, 33: 1058-1066. PMID: 40342236, PMCID: PMC12119222, DOI: 10.1002/oby.24289.Peer-Reviewed Original ResearchConceptsBinge-eating disorderED psychopathologyWeight loss treatmentExacerbate eating disordersBinge-eating frequencyPsychopathology scoresBinge eatingSymptoms of binge eatingBehavioral weight loss treatmentIncreased symptomsEating disordersPsychopathologyFollow-upDisordersPosttreatmentHeterogeneity of outcomesEatingSecondary analysisFrequency of casesCoexisting obesityClinical contextParticipantsIndividual levelBingeObesity452. Examining the Role of the Kappa Opioid Receptor in Trauma-Related Psychopathology and Chronic Pain Using [11C]EKAP Positron Emission Tomography
Weiss E, Hart-Derrick V, Freeman D, Miller R, Hillmer A, Wagner A, Matuskey D, Esterlis I, Davis M. 452. Examining the Role of the Kappa Opioid Receptor in Trauma-Related Psychopathology and Chronic Pain Using [11C]EKAP Positron Emission Tomography. Biological Psychiatry 2025, 97: s283. DOI: 10.1016/j.biopsych.2025.02.690.Peer-Reviewed Original ResearchBeyond screen time: The core influences of problematic screen use on adolescent development networks.
Xu L, Song K, Deng H, Geng X, Zhang J, Fang X, Potenza M, Zhang J. Beyond screen time: The core influences of problematic screen use on adolescent development networks. Journal Of Behavioral Addictions 2025 PMID: 40293811, DOI: 10.1556/2006.2025.00035.Peer-Reviewed Original ResearchAdolescent Brain Cognitive DevelopmentFunctional impairmentCross-sectional networksSelf-reported screen timeSelf-report questionnairesAdolescent well-beingChecking behaviorBehavioral tendenciesCognitive developmentProblematic useMotivational aspectsScreen timeScreen useStronger connectionsImpairmentHigh centralityWell-beingPredictive effectYouthAdolescentsFollow-upPsychopathologyScreening habitsScreening activitiesCohort dataDiurnal changes of salivary oxytocin in healthy and psychiatric adolescents
Gizuterman A, Zgoory-Sharon O, Avirame K, Mevorach T, Foul Y, Feldman R, Eitan R. Diurnal changes of salivary oxytocin in healthy and psychiatric adolescents. Journal Of Psychiatric Research 2025, 186: 273-279. PMID: 40267842, DOI: 10.1016/j.jpsychires.2025.04.007.Peer-Reviewed Original ResearchConceptsSalivary oxytocinMeasures of emotion regulationCompleted self-report questionnairesPsychiatric inpatient wardsSelf-report questionnairesMental health stateEmotion regulationPsychiatric adolescentsYouth mental healthPsychiatric assessmentOxytocin levelsInterpersonal relationshipsDiurnal rhythmMental healthPsychopathologyOxytocin productionHealthy controlsOxytocinDaily time pointsHealthy peersAdolescent patientsAdolescentsBaseline levelsConsecutive daysPatient groupAutistic traits in childhood and post‐traumatic stress disorder as young adults: a cohort study
Quinton A, Rumball F, Ronald A, Fisher H, Arseneault L, Happé F, Danese A. Autistic traits in childhood and post‐traumatic stress disorder as young adults: a cohort study. Journal Of Child Psychology And Psychiatry 2025 PMID: 40133042, DOI: 10.1111/jcpp.14163.Peer-Reviewed Original ResearchPost-traumatic stress disorderLifetime PTSD diagnosisChildhood Autism Spectrum TestLifetime trauma exposureAutistic traitsPTSD diagnosisStress disorderTrauma exposureIntelligence quotientTraumatic experiencesDevelopment of post-traumatic stress disorderAssociated with greater reportsTrauma-exposed young peopleTrauma-related psychopathologyTrauma-exposed childrenChildhood traumatic experiencesAssociation of autistic traitsSame-sex twinsEvidence-based treatmentsFamily socioeconomic statusGeneral psychopathologyDiagnosing autistic childrenSocioeconomic statusPsychopathologyAutistic adultsCharacterizing Social Communication Difficulties in Young Children within a Longitudinal Ecological Systems Framework
Perlstein S, Njoroge W, White L, Parish-Morris J, Williams A, Malone K, Rodriguez Y, Sun S, Wisniewski K, Popoola A, Flum M, Kornfield S, Seidlitz J, Chaiyachati B, Barzilay R, Gur R, Waller R. Characterizing Social Communication Difficulties in Young Children within a Longitudinal Ecological Systems Framework. Research On Child And Adolescent Psychopathology 2025, 53: 485-497. PMID: 40122964, PMCID: PMC12031844, DOI: 10.1007/s10802-025-01308-y.Peer-Reviewed Original ResearchConceptsSocial communication difficultiesLower household incomeCommunication difficultiesNeighborhood resourcesMaternal bondingRatings of child behaviorTransdiagnostic risk factorParent-report questionnaireHousehold incomeProspective risk factorsParent-child dyadsRisk factorsTransdiagnostic riskChild psychopathologyEcological systems frameworkAged 2Child behaviorAged 1Young ChildrenPsychopathologyEarly interventionProspective riskGeocoded dataDyadsGestational ageGambling disorder and problematic pornography use: Does co-occurrence influence treatment outcome?
Mestre-Bach G, Potenza M, Granero R, Håkansson A, Gómez-Peña M, Perales I, Vicó À, Uríszar J, Fernández-Aranda F, Sánchez I, Jiménez-Murcia S. Gambling disorder and problematic pornography use: Does co-occurrence influence treatment outcome? Journal Of Behavioral Addictions 2025, 14: 465-479. PMID: 40116860, PMCID: PMC11974433, DOI: 10.1556/2006.2025.00023.Peer-Reviewed Original ResearchConceptsCognitive-behavioral therapyGambling disorderPornography useEmotion regulationGD severityTreatment outcomesCognitive-behavioral therapy approachCognitive-behavioral therapy sessionsTreatment outcomes of individualsCo-occurrence of GDCo-occurrenceMental health concernsImprove treatment adherenceBehavioral addictionsTreatment dropoutOutcomes of individualsWeekly sessionsTreatment adherencePsychopathologyGamblingSessionsDisordersAssociated with higher likelihoodRelapseImpulseParsing the heterogeneity of social motivation in autism
Chetcuti L, Hardan A, Spackman E, Loth E, McPartland J, Frazier T, Youngstrom E, Uljarevic M. Parsing the heterogeneity of social motivation in autism. Journal Of Child Psychology And Psychiatry 2025 PMID: 40091308, DOI: 10.1111/jcpp.14147.Peer-Reviewed Original ResearchCo-occurring psychopathologySocial motivationSocial functioningFactor analysis of symptomsNature of deficitsHealthy Brain NetworkLatent profile analysisSubgroup of autismDiagnostic boundariesAutism phenotypeCognitive abilitiesAnalysis of symptomsBrain networksScreening measuresAutismMild challengeSubgroup differencesPsychopathologyChronological ageTailored interventionsDeficitsProfile analysisMotivationAnalysis of varianceNormative benchmarkKleptomania on the impulsive–compulsive spectrum. Clinical and therapeutic considerations for women
Munguía L, Baenas-Soto I, Granero R, Fábregas-Balcells M, Gaspar-Pérez A, Rosinska M, Potenza M, Cuquerella Á, Tapia-Martínez J, Cabús-Grange R, Taranilla-Castro A, Macharé-Alberni M, Talón-Navarro M, Fernández-Aranda F, Jiménez-Murcia S. Kleptomania on the impulsive–compulsive spectrum. Clinical and therapeutic considerations for women. Scientific Reports 2025, 15: 7886. PMID: 40050325, PMCID: PMC11885670, DOI: 10.1038/s41598-025-85705-9.Peer-Reviewed Original ResearchConceptsImpulsive-compulsive spectrumDSM-5 criteriaClinical groupsDSM-5Personality featuresSemi-structured clinical interviewTreatment outcomesHarm avoidance scoresCognitive behavioral treatmentHealthy control individualsSample of female patientsImpact treatment outcomesPoor treatment outcomesCompulsive featuresBehavioral treatmentHigher impulsivityAvoidance scoresClinical interviewKleptomaniaInvestigate treatment outcomesCharacteristics of peopleFemale participantsPsychopathologyClinical samplesTreatment approachesImpact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study
Ota V, Oliveira A, Bugiga A, Conceição H, Galante P, Asprino P, Schäfer J, Hoffmann M, Bressan R, Brietzke E, Manfro G, Grassi-Oliveira R, Gadelha A, Rohde L, Miguel E, Pan P, Santoro M, Salum G, Carvalho C, Belangero S. Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study. Frontiers In Psychiatry 2025, 16: 1505421. PMID: 40018685, PMCID: PMC11866055, DOI: 10.3389/fpsyt.2025.1505421.Peer-Reviewed Original ResearchBrazilian High-Risk Cohort StudyChild Behavior ChecklistHigh Risk Cohort StudyLife adversityPsychiatric symptomsExternalizing symptomsDevelopment of psychiatric symptomsAssociated with depressive symptomsEarly life adversityStressful life eventsAssociated with psychiatric phenotypesPsychiatric phenotypesBehavior ChecklistDepressive symptomsLife eventsMental disordersPsychopathologyNo mediationChild maltreatmentCohort studyLatent factorsAssociated with deprivationAdversityModerating effectMental conditionNew diagnosis in psychiatry: beyond heuristics
McGorry P, Hickie I, Kotov R, Schmaal L, Wood S, Allan S, Altınbaş K, Boyce N, Bringmann L, Caspi A, Cuthbert B, Gawęda Ł, Groen R, Guloksuz S, Hartmann J, Krueger R, Mei C, Nieman D, Öngür D, Raballo A, Scheffer M, Schreuder M, Shah J, Wigman J, Yuen H, Nelson B. New diagnosis in psychiatry: beyond heuristics. Psychological Medicine 2025, 55: e26. PMID: 39911018, PMCID: PMC12017357, DOI: 10.1017/s003329172400223x.Peer-Reviewed Original ResearchConceptsHierarchical Taxonomy of PsychopathologyMechanisms of mental disordersTaxonomy of PsychopathologyResearch Domain CriteriaTransdiagnostic modelTransdiagnostic researchMental disordersHierarchical taxonomyCategorical approachMental healthRDoCHiTOPPsychiatryNosologyResearch utilizationClinical utilityParadigmPsychopathologyHeuristic modelDSMDisordersIllnessResearchNew diagnosesClinicRepresenting brain-behavior associations by retaining high-motion minoritized youth
Ramduny J, Uddin L, Vanderwal T, Feczko E, Fair D, Kelly C, Baskin-Sommers A. Representing brain-behavior associations by retaining high-motion minoritized youth. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2025 PMID: 39921132, DOI: 10.1016/j.bpsc.2025.01.014.Peer-Reviewed Original ResearchBrain-behavior associationsFunctional MRIAdolescent Brain Cognitive Development<sup>SM<Effect sizeHispanic youthInternalizing psychopathologyCognitive performanceParticipant sexFunctional connectivityFMRI dataMinoritized individualsWhite youthHead motionMinoritized youthYouthSources of noisePsychopathologyDiverse populationsRacial/ethnic groupsAssociationPartial Spearman rank correlationsAdolescentsDisproportionate numberTrauma-related psychopathologies after extracorporeal membrane oxygenation support: A systematic review and meta-analysis.
Demory A, Broden E, Equey L, Funaro M, Sharifi M, Harpaz-Rotem I, Traube C, Karam O. Trauma-related psychopathologies after extracorporeal membrane oxygenation support: A systematic review and meta-analysis. Perfusion 2025, 2676591251317919. PMID: 39879146, DOI: 10.1177/02676591251317919.Peer-Reviewed Original ResearchPrevalence of post-traumatic stress disorderTrauma-related psychopathologyExtracorporeal membrane oxygenationPediatric ECMO patientsAdult ECMO patientsAssociated with substantial psychiatric morbidityPost-traumatic stress disorderPrevalence of PTSDECMO survivorsECMO patientsPooled prevalence of anxietyPrevalence of anxietyStress disorderPooled prevalencePrevalence of depressionPsychiatric morbidityPsychopathologyMeta-analysisExtracorporeal membrane oxygenation supportExtracorporeal membrane oxygenation useExtracorporeal membrane oxygenation survivorsMembrane oxygenation supportAnxietySystematic reviewPooled prevalence of depressionSexual trauma and compulsive sexual behavior in young men and women: A network analysis involving two samples
Scoglio A, Chen Y, Huang K, Borgogna N, Potenza M, Blycker G, Kraus S. Sexual trauma and compulsive sexual behavior in young men and women: A network analysis involving two samples. Journal Of Behavioral Addictions 2025, 14: 166-177. PMID: 39841161, PMCID: PMC11974438, DOI: 10.1556/2006.2024.00074.Peer-Reviewed Original ResearchCompulsive sexual behaviorSexual trauma historySexual traumaSexual behaviorTrauma historyPsychological distressSubstance useSample of young adultsCo-occurring psychopathologyGender differencesSignificant gender differencesTime of traumaSample 1Young adultsDistressSupportive relationshipsTransactional sexNegative healthCentral nodeClinical concernPsychopathologyTraumaBehaviorSocial conditionsSexHeterogeneity in Developmental Trajectories of Internalizing and Externalizing Symptomatology: Associations with Risk and Protective Factors
Brieant A, Cai T, Ip K, Holt-Gosselin B, Gee D. Heterogeneity in Developmental Trajectories of Internalizing and Externalizing Symptomatology: Associations with Risk and Protective Factors. Child Psychiatry & Human Development 2025, 1-12. PMID: 39786680, DOI: 10.1007/s10578-024-01804-0.Peer-Reviewed Original ResearchAdolescent Brain Cognitive DevelopmentHigh-decreasing classModerate-increasing classTrajectories of psychopathologyNegative life eventsLow-stable classSample of youthLow-decreasing classGrowth mixture modelingProtective factorsExternalizing symptomatologyPsychopathological trajectoriesExternalizing symptomsProportion of youthLife eventsDevelopmental trajectoriesPsychopathologyCognitive developmentExternalizing trajectoriesTrajectory classesParental acceptanceLatent classesDevelopmental patternsInternational trajectoriesCo-developmentDevelopment as a Multi-Systemic Endeavor: Personal and Professional Reflections on S. J. Blatt’s Philosophy of Development
Shahar G, Mayes L. Development as a Multi-Systemic Endeavor: Personal and Professional Reflections on S. J. Blatt’s Philosophy of Development. Psychoanalytic Inquiry 2025, 45: 7-16. DOI: 10.1080/07351690.2025.2451007.Peer-Reviewed Original ResearchTheory of psychological developmentAcademic psychologyDevelopmental psychologyPsychological developmentPhilosophy of developmentBlattLife circumstancesMetaphysical assumptionsHuman natureAreas of psychoanalysisPsychologyArea of scholarshipPersonal upbringingComprehensive theorySeminal contributionsHolistic thinkingPersonsLife storiesPsychopathologyLife spanHuman developmentThinkingProfessional reflectionPsychoanalysisPhilosophy
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