2025
Interacting immediate and long-term action regulation in suicidal behavior
Murphy N, Kypriotakis G, Lijffijt M, Iqbal S, Iqbal T, Amarneh D, O’Brien B, Tamman A, Thomas Y, Moukaddam N, Kosten T, Averill L, Mathew S, Swann A. Interacting immediate and long-term action regulation in suicidal behavior. Journal Of Mood And Anxiety Disorders 2025, 10: 100118. DOI: 10.1016/j.xjmad.2025.100118.Peer-Reviewed Original ResearchImmediate memory taskInternal State ScaleLifetime cumulative adversityChildhood traumaSuicidal behaviorAction regulationSuicidal ideationSuicide attemptsTreatment of suicide riskSSI-WConventional psychiatric diagnosesSevere suicide attemptsRegulation of actionsPsychiatric controlsMemory taskAddictive behaviorsPsychiatric diagnosisEarly traumaSuicide riskSuicidal crisisBehavioral symptomsStimulus discriminationCumulative adversityState scaleSuicideA Picture Worth More Than One Thousand Words: A 30-Year Review of Photovoice Representation Disparities in Psychiatric Research
Metaweh M, Ouellette R, Moses J, Frazier S. A Picture Worth More Than One Thousand Words: A 30-Year Review of Photovoice Representation Disparities in Psychiatric Research. American Journal Of Orthopsychiatry 2025 PMID: 40323854, DOI: 10.1037/ort0000851.Peer-Reviewed Original ResearchPsychiatric researchSchizophrenia spectrum disordersSubstance use disordersSevere mental illnessMental health modelObsessive-compulsiveStressor disordersParticipants' social identitySubstance-relatedPsychiatric diagnosisInternalizing disordersSpectrum disorderMental illnessQuarter of studiesDisordersParticipants' representationsDiagnostic criteriaSocial identityHealth modelThousand WordsParticipantsSchizophreniaTherapeutic interventionsSocial justice approachPsychiatricSelf-Inflicted Head Injury in Behavioral Variant Frontotemporal Dementia with Compulsive Behaviors: A Case Report
Yang Y, Matuskey D, Benjamin C, Fesharaki-Zadeh A. Self-Inflicted Head Injury in Behavioral Variant Frontotemporal Dementia with Compulsive Behaviors: A Case Report. Cognitive And Behavioral Neurology 2025, 38: 66-72. PMID: 40298273, DOI: 10.1097/wnn.0000000000000392.Peer-Reviewed Original ResearchConceptsBehavioral variant frontotemporal dementiaDiagnosis of behavioural variant frontotemporal dementiaFrontotemporal dementiaEpisodic memory lossLoss of empathyCompulsive behaviorsExecutive functionProgressive behavioral deficitsPsychiatric diagnosisPsychiatric disordersBehavioral deficitsRight hippocampusRight hemisphereBehavioral agitationPersonality changesNeuroimaging findingsInstrumental activities of daily livingMemory lossRight lateral ventricleSevere hypometabolismLateral ventricleParenchymal volume lossClinician's abilityInstrumental activitiesVolume lossUnraveling the Neural Landscape of Mental Disorders using Double Functional Independent Primitives (dFIPs)
Soleimani N, Iraji A, Pearlson G, Preda A, Calhoun V. Unraveling the Neural Landscape of Mental Disorders using Double Functional Independent Primitives (dFIPs). Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2025 PMID: 40222638, DOI: 10.1016/j.bpsc.2025.03.015.Peer-Reviewed Original ResearchAutism spectrum disorderFunctional network connectivityBipolar disorderPsychiatric conditionsMental disordersMental illnessResting-state functional magnetic resonance imagingFunctional magnetic resonance imagingConnectivity patternsBrain network alterationsFunctional connectivity patternsNeurobiological underpinningsDepressive disorderEmotion regulationNeural signaturesPsychiatric diagnosisConnectivity alterationsBrain regionsSpectrum disorderCognitive functionNeural landscapeCerebellar connectivitySocial behaviorNetwork alterationsSchizophreniaAssociation of psychiatric diagnoses and military sexual trauma type with denied posttraumatic stress disorder service connection
Webermann A, Coppola E, Lazar C, Rosen M, Murdoch M, Portnoy G, Black A. Association of psychiatric diagnoses and military sexual trauma type with denied posttraumatic stress disorder service connection. Journal Of Affective Disorders 2025, 381: 69-76. PMID: 40185410, DOI: 10.1016/j.jad.2025.03.171.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderMilitary sexual traumaPTSD service connectionPsychiatric diagnosisPosttraumatic stress disorder diagnostic criteriaDiagnosis of personality disorderPosttraumatic stress disorder symptomsPosttraumatic stress disorder diagnosisAssociation of psychiatric diagnosesSchizophrenia spectrum disordersSubstance use disordersPersonality disorderAnxiety disordersNon-PTSDStress disorderBipolar disorderTrauma typesSexual traumaSpectrum disorderSexual assault claimsDisordersService connectionVeteransDiagnostic criteriaSexual harassment claimsA multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis
Peng P, Hao Y, Zhang X, Ma Y, Liu X, Shen D, Shen W, Zhao B, Li D, Beck S, Nunez Y, Potenza M, Gelernter J, Liu T, Yang B. A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis. Annals Of General Psychiatry 2025, 24: 12. PMID: 40033412, PMCID: PMC11877697, DOI: 10.1186/s12991-025-00546-0.Peer-Reviewed Original ResearchSemi-Structured Assessment for Drug Dependence and AlcoholismDSM-5 diagnostic criteriaGambling disorderDSM-5Antisocial personality disorderMethamphetamine use disorderSubstance use disordersDiagnostic criteriaPersonality disorderBridge symptomsDepressive episodeDrug rehabilitation centersCentral symptomsPsychiatric diagnosisGambling durationUse disorderSelf-harmChildhood experiencesMethamphetamineAlcohol useViolent experiencesDisordersManifest symptomsChinese versionMDEA generalized reward processing deficit pathway to negative symptoms across diagnostic boundaries
Spilka M, Millman Z, Waltz J, Walker E, Levin J, Powers A, Corlett P, Schiffman J, Gold J, Silverstein S, Ellman L, Mittal V, Woods S, Zinbarg R, Strauss G. A generalized reward processing deficit pathway to negative symptoms across diagnostic boundaries. Psychological Medicine 2025, 55: e6. PMID: 39901872, PMCID: PMC11968125, DOI: 10.1017/s003329172400326x.Peer-Reviewed Original ResearchConceptsNegative symptomsDiagnostic boundariesPsychiatric diagnosisTransdiagnostic sample of youthProcessing profilesEffort-cost computationsPositive valence systemsElevated negative symptomsHelp-seeking participantsClinical high riskClinical group membershipSample of youthHedonic reactivityTransdiagnostic sampleCHR criteriaNeurobiological mechanismsPsychosis riskSubgroup of participantsBehavioral tasksClinical interviewPsychiatric disordersClinical participantsValence systemsGroup membershipDiagnostic classificationSocial functioning and frontal alpha asymmetry in schizophrenia
Farina E, Assaf M, Corbera S, Choi J, Yantz C, Chen C. Social functioning and frontal alpha asymmetry in schizophrenia. Journal Of Psychiatric Research 2025, 182: 74-82. PMID: 39799666, PMCID: PMC11830537, DOI: 10.1016/j.jpsychires.2025.01.006.Peer-Reviewed Original ResearchConceptsFrontal alpha asymmetryAutism spectrum disorderReduced social functioningSocial functioningNeurophysiological markersAlpha asymmetryPsychiatric disordersAtypical social behaviorUnique to schizophreniaSelf-report measuresHealthy controlsResting-state electroencephalogramClinical interviewPsychiatric diagnosisSchizophreniaSpectrum disorderDiagnostic groupsReduced motivationSocial behaviorDisordersEmotional tendencyAnalysis of varianceClinical manifestationsElectroencephalogramAutism
2024
Eating Disorders, Co‐Morbid Disorders and Early Risk Factors Amongst Post‐9/11 Veteran Men and Women
Cooper Z, Smith B, Kehle‐Forbes S, Dorset J, Mitchell K. Eating Disorders, Co‐Morbid Disorders and Early Risk Factors Amongst Post‐9/11 Veteran Men and Women. Journal Of Clinical Psychology 2024, 81: 133-144. PMID: 39648640, PMCID: PMC11802485, DOI: 10.1002/jclp.23756.Peer-Reviewed Original ResearchCo-occurring psychiatric disordersRates of eating disordersPosttraumatic stress disorderPsychiatric disordersEating disordersMilitary risk factorsStress disorderLevels of posttraumatic stress disorderCo-morbid psychiatric disordersCo-morbid psychiatric diagnosesDSM-5 eating disorder diagnosesComorbid psychiatric disordersBinge eating disorderCo-morbid disordersEating disorder diagnosisDocumented risk factorsLongitudinal studyEvidence-based treatmentsNon-veteransRisk factorsEarly risk factorsDSM-5Case statusDisorder onsetPsychiatric diagnosisIdentifying diagnosed major chronic diseases associated with recent housing instability among aging adults: data from the ‘All of Us’ research program
Beydoun H, Vieytes C, Beydoun M, Lampros A, Tsai J. Identifying diagnosed major chronic diseases associated with recent housing instability among aging adults: data from the ‘All of Us’ research program. Journal Of Public Health 2024, 47: 15-23. PMID: 39586798, PMCID: PMC12034092, DOI: 10.1093/pubmed/fdae300.Peer-Reviewed Original ResearchUs Research ProgramHousing instabilityAging adultsChronic diseasesOdds ratioChronic disease preventionAssociated with lower oddsPsychiatric diagnosisConfidence intervalsElectronic health recordsAssociated with psychiatric diagnosesEstimate odds ratiosCardiovascular diseaseMultivariate logistic regression modelDiverse group of adultsLogistic regression modelsTreatment of chronic diseasesCross-sectional dataHealth recordsHealthcare utilizationLower oddsGroup of adultsYears of ageDiagnosed diabetesCancer diagnosisDark night of the soul: the lived experience and meaning of mental health crisis
Roennfeldt H, Wyder M, Castles C, Hill N, Byrne L, Hamilton B. Dark night of the soul: the lived experience and meaning of mental health crisis. Advances In Mental Health 2024, ahead-of-print: 1-15. DOI: 10.1080/18387357.2024.2428308.Peer-Reviewed Original ResearchMental health crisisCrisis servicesEmergency departmentPerspectives of peoplePerson's own understandingHealth crisisRisk of harmCrisis careMental illnessExistential explanationsPsychiatric diagnosisPsychiatric disordersPhenomenological studyLived experienceHuman conditionSuicidePhone linesParticipantsSubjective meaningPeopleFuller understandingRiskServicesCrisis experienceCareConvergent Validity of Experimental Cognitive Tests in a Large Community Sample.
Dean A, Pochon J, Bilder R, Sabb F, Congdon E, Ghahremani D, Karlsgodt K, van Erp T, Schwarzlose R, Cannon T, Freimer N, London E. Convergent Validity of Experimental Cognitive Tests in a Large Community Sample. Assessment 2024, 10731911241283410. PMID: 39523501, DOI: 10.1177/10731911241283410.Peer-Reviewed Original ResearchExperimental cognitive testsConvergent validityInhibitory controlFactor analysisCognitive testsBalloon Analogue Risk TaskTests of working memoryMultigroup confirmatory factor analysisDelay-discounting taskReversal learning taskStop-signal taskExperimental cognitive measuresTraditional neuropsychological testsAttention Network TestThree-factor structureConfirmatory factor analysisExploratory factor analysisDiscounting taskRemember-knowRisk TaskTask switchingCognitive measuresNeuropsychological testsCognitive domainsPsychiatric diagnosisGender identity differences in age of first mental health diagnosis: A population-based study of childhood and adolescence
Bränström R, Pachankis J. Gender identity differences in age of first mental health diagnosis: A population-based study of childhood and adolescence. European Journal Of Public Health 2024, 34: ckae144.063. PMCID: PMC11516791, DOI: 10.1093/eurpub/ckae144.063.Peer-Reviewed Original ResearchMental health disordersHealth care registriesPopulation-based sampleHealth disordersCare registriesSwedish National Public Health SurveyNational health care registriesNational Public Health SurveyRisk of mental health disordersIncreased risk of mental health disordersPublic health surveyGender identity disparitiesMental health diagnosesPopulation-based evidenceIncreased riskPopulation-based studyBenefits of interventionsCisgender individualsDiagnosis riskHealth SurveyHealth diagnosisAge 8 yearsTreatment history dataPsychiatric diagnosisIncreased likelihoodW15. A MULTIVARIATE GENOMIC INVESTIGATION OF THE EXTERNALIZING SPECTRUM AND SUICIDE RISK
Barr P, Bigdeli T, Sanchez-Roige S, Mallard T, Ashley-Koch A, Dick D, Harden P, Hauser B, Qin X, Aslan M, Harvey P, Beckham J, Kimbrel N. W15. A MULTIVARIATE GENOMIC INVESTIGATION OF THE EXTERNALIZING SPECTRUM AND SUICIDE RISK. European Neuropsychopharmacology 2024, 87: 108. DOI: 10.1016/j.euroneuro.2024.08.224.Peer-Reviewed Original ResearchSuicide attemptsSuicidal ideationPolygenic scoresAssociated with suicide attemptsGenomic structural equation modelingLifetime suicide riskRisk factors associated with suicideExternalizing polygenic scoresLifetime suicide attemptsSubstance use disordersFactors associated with suicideSubstance-use behaviorsExternalizing spectrumExternalizing disordersBipolar disorderPsychiatric diagnosisSuicide riskStructural equation modelingResults Preliminary resultsSuicidal phenotypeGenome-wide association studiesPersonality indicesIdeationSuicideCohort of veterans94. THE GENETIC ARCHITECTURE OF MOOD AND ANXIETY DISORDER SYMPTOMS
Schultz L, Mollon J, Jacquemont S, Almasy L, Glahn D. 94. THE GENETIC ARCHITECTURE OF MOOD AND ANXIETY DISORDER SYMPTOMS. European Neuropsychopharmacology 2024, 87: 100. DOI: 10.1016/j.euroneuro.2024.08.208.Peer-Reviewed Original ResearchEuropean ancestryPrefrontal cortexPsychiatric diagnosisGene set analysisAssociated with genesInverse-variance weighted meta-analysisICD-10 psychiatric diagnosisMeta-analysisAnxiety disorder symptomsUK Biobank (UKBMulti-ancestry meta-analysisGenome-wide significant variantsGenetic architectureRisk lociMSigDB geneChromosome 8Confirmatory factor modelsGenomic risk lociEuropean ancestry individualsAnxiety disordersDisorder symptomsMood/anxiety symptomsIdentified risk lociDopamine receptorsFrontal cortexDECIPHERING THE UNDERLYING BIOLOGY OF PSYCHIATRIC DISORDERS THROUGH LONGITUDINAL FAMILY COHORT BASED STUDIES IN INDIA
Viswanath B, Sud R, Ganesh S, Mahadevan J, Holla B, Paul P, Purushottam M, Jain S, Consortium A. DECIPHERING THE UNDERLYING BIOLOGY OF PSYCHIATRIC DISORDERS THROUGH LONGITUDINAL FAMILY COHORT BASED STUDIES IN INDIA. European Neuropsychopharmacology 2024, 87: 43-44. DOI: 10.1016/j.euroneuro.2024.08.108.Peer-Reviewed Original ResearchAdverse childhood eventsWhole-exome sequencingFirst-degree relativesChildhood eventsStudies of psychiatric disordersFamily history densityObsessive compulsive disorderGenetic studies of psychiatric disordersSubstance use disordersPeripheral blood mononuclear cellsSevere mental illnessLongitudinal family cohortGenetic studiesAge-of-onsetTransdiagnostic endophenotypesBrain imaging abnormalitiesCompulsive disorderBipolar disorderPsychiatric diagnosisPsychiatric disordersMultiple affected membersCognitive performanceRare damaging variantsMental illnessCognitive AssessmentF67. CHARACTERIZING THE IMPACT OF AUTOZYGOSITY AND RUNS OF HOMOZYGOSITY ON PSYCHIATRIC DISEASE RISK IN INDIAN POPULATION
Kandasamy K, Ganesh S, Sachdeva P, Mahadevan J, Holla B, Benegal V, Purushottam M, Jain S, Viswanath B. F67. CHARACTERIZING THE IMPACT OF AUTOZYGOSITY AND RUNS OF HOMOZYGOSITY ON PSYCHIATRIC DISEASE RISK IN INDIAN POPULATION. European Neuropsychopharmacology 2024, 87: 242. DOI: 10.1016/j.euroneuro.2024.08.478.Peer-Reviewed Original ResearchGenetic architecture of psychiatric disordersIllumina Global Screening ArrayGlobal Screening ArrayContinental populationsGenetic architectureInbreeding coefficientRecessive locusAutozygosityFROHObsessive compulsive disorderScreening ArrayPLINK v.GenomeInbreedingBipolar disorderDisease-riskPsychiatric diagnosisPsychiatric disordersDisease riskEndogamyIlluminaCase-control differencesLociPLINKROHImpact of adverse childhood experiences on risk for internalizing psychiatric disorders in youth at clinical high-risk for psychosis
Giampetruzzi E, Walker E, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Woods S, LoPilato A. Impact of adverse childhood experiences on risk for internalizing psychiatric disorders in youth at clinical high-risk for psychosis. Psychiatry Research 2024, 342: 116214. PMID: 39368239, PMCID: PMC11617268, DOI: 10.1016/j.psychres.2024.116214.Peer-Reviewed Original ResearchAdverse childhood experiencesClinical high riskEffects of protective factorsInternalizing disordersDepressive disorderCHR-PEmotional neglectSelf-harm/suicideProtective factorsChildhood experiencesHigher levels of adverse childhood experiencesHistory of depressive disorderSexual abuseLevels of adverse childhood experiencesInternalizing psychiatric disordersChildhood sexual abusePresence of protective factorsImpact of adverse childhood experiencesAnxiety disordersAdministered measuresPsychiatric diagnosisPsychiatric disordersPsychiatric outcomesChild adversitySubstance useCentral and peripheral physiological responses to decision making in hoarding disorder
Levy H, Naples A, Collett S, McPartland J, Tolin D. Central and peripheral physiological responses to decision making in hoarding disorder. International Journal Of Psychophysiology 2024, 205: 112437. PMID: 39265723, PMCID: PMC11502253, DOI: 10.1016/j.ijpsycho.2024.112437.Peer-Reviewed Original ResearchError-related negativityHoarding disorderControl participantsAlpha asymmetryPsychophysiological responsesIncreased frontal negativityGo/No-Go taskHealthy control participantsDecision-making taskPeripheral nervous system activityResponse to decisionsAnxiety disordersFrontal negativityNeurobiological modelsGo taskNeutral taskPsychiatric diagnosisExcessive clutterPsychophysiological measuresPersonal possessionsExaggerated activationDisordersNull resultsNervous system activityTaskMild Traumatic Brain Injury in U.S. Military Veterans: Results from the National Health and Resilience in Veterans Study
Meshberg-Cohen S, Cook J, Fischer I, Pietrzak R. Mild Traumatic Brain Injury in U.S. Military Veterans: Results from the National Health and Resilience in Veterans Study. Psychiatry 2024, 87: 314-328. PMID: 39186319, DOI: 10.1080/00332747.2024.2392226.Peer-Reviewed Original ResearchMild traumatic brain injuryNational Health and ResilienceU.S. military veteransPsychosocial functioningTraumatic brain injuryVeterans StudyMilitary veteransCurrent posttraumatic stress disorderOutcomes of mild traumatic brain injuryLifetime psychiatric conditionsGeneralized anxiety disorderComorbid psychiatric diagnosesPosttraumatic stress disorderPoor psychosocial functioningMild traumatic brain injury eventDrug use disordersBrain injuryPrevention of disabilityAssociated with increased oddsAnxiety disordersDepressive disorderStress disorderPsychiatric diagnosisMTBI symptomsPsychiatric characteristics
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