2025
Psychometric properties of the Reward Deficiency Syndrome Questionnaire among a non-clinical sample and its relationship with the characteristics of potentially addictive behaviors
Kotyuk E, Demetrovics Z, Urbán R, Czakó A, Blum K, Griffiths M, Potenza M, Efrati Y. Psychometric properties of the Reward Deficiency Syndrome Questionnaire among a non-clinical sample and its relationship with the characteristics of potentially addictive behaviors. Addictive Behaviors Reports 2025, 21: 100598. PMID: 40248688, PMCID: PMC12005299, DOI: 10.1016/j.abrep.2025.100598.Peer-Reviewed Original ResearchReward Deficiency SyndromeCompulsive buying-shopping disorderInternet gaming disorderAddictive behaviorsBehavioral addictionsGambling disorderDevelopment of addictive behaviorsBuying-shopping disorderNon-clinical samplePotential behavioral addictionsProblematic substance useAssociated with anxietyIsraeli young adultsPsychometrically sound instrumentNatural rewardsCompulsive personalityFactor structureGaming disorderProblematic behaviorsSubstance useSocial media usePersonal characteristicsPsychological featuresSound instrumentHebrew version
2018
The L-type calcium channel blocker, isradipine, attenuates cue-induced cocaine-seeking by enhancing dopaminergic activity in the ventral tegmental area to nucleus accumbens pathway
Addy NA, Nunes EJ, Hughley SM, Small KM, Baracz SJ, Haight JL, Rajadhyaksha AM. The L-type calcium channel blocker, isradipine, attenuates cue-induced cocaine-seeking by enhancing dopaminergic activity in the ventral tegmental area to nucleus accumbens pathway. Neuropsychopharmacology 2018, 43: 2361-2372. PMID: 29773910, PMCID: PMC6180103, DOI: 10.1038/s41386-018-0080-2.Peer-Reviewed Original ResearchConceptsL-type calcium channelsCocaine relapseLever depressionVentral tegmental areaCocaine self-administration trainingOriginal training contextLight cue presentationSelf-administration trainingSubjective effectsCocaine-seeking behaviorTegmental areaBehavioral effectsCocaine's subjective effectsL-type calcium channel blockerCue presentationMale Sprague-Dawley ratsTraining contextCocaine cuesNucleus accumbens coreNatural rewardsDA receptor activationCalcium channel blockersSprague-Dawley ratsPhasic dopaminePotential therapeutic target
2017
The experience sampling method as an mHealth tool to support self‐monitoring, self‐insight, and personalized health care in clinical practice
van Os J, Verhagen S, Marsman A, Peeters F, Bak M, Marcelis M, Drukker M, Reininghaus U, Jacobs N, Lataster T, Simons C, Investigators E, Lousberg R, Gülöksüz S, Leue C, Groot P, Viechtbauer W, Delespaul P. The experience sampling method as an mHealth tool to support self‐monitoring, self‐insight, and personalized health care in clinical practice. Depression And Anxiety 2017, 34: 481-493. PMID: 28544391, DOI: 10.1002/da.22647.Peer-Reviewed Original ResearchConceptsExperience sampling methodClinical practiceTrial of MindfulnessESM data collectionPersonalized trajectoriesEmotion dynamicsCognitive abilitiesRoutine clinical practiceDifferent patient groupsNatural rewardsRoutine outcome measurementDaily lifeBlended careMix of faceImplicit patternsMental healthSmartphone usePatient groupOffice treatmentTwin studiesOutcome measurementsProcess of diagnosisMHealth toolsTreatment evaluationDecision making
2003
Phospholipase Cγ in Distinct Regions of the Ventral Tegmental Area Differentially Modulates Mood-Related Behaviors
Bolaños C, Perrotti L, Edwards S, Eisch A, Barrot M, Olson V, Russell D, Neve R, Nestler E. Phospholipase Cγ in Distinct Regions of the Ventral Tegmental Area Differentially Modulates Mood-Related Behaviors. Journal Of Neuroscience 2003, 23: 7569-7576. PMID: 12930795, PMCID: PMC6740761, DOI: 10.1523/jneurosci.23-20-07569.2003.Peer-Reviewed Original ResearchConceptsVentral tegmental areaDrugs of abuseAnxiety-like behaviorOverexpression of PLCgamma1Nociceptive stimuliTegmental areaAversive stimuliCaudal ventral tegmental areaDrug-induced elevationMood-related behaviorsMorphine place preferenceMorphine-paired compartmentDistinct topographical regionsViral-mediated gene transferEmotional stimuliNeurotrophic factorNeural substratesNatural rewardsPlace preference
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