2025
Neighborhood Deprivation, Trauma Profiles, Coping, and Stress Prospectively Predict Depressive Symptoms Among Young African American Mothers in the InterGEN Study: A Latent Class Analysis
Lane B, Millender E, Harris R, Nowak A, Josiah N, Hall C, Pfeiffer F, Wong F, Crusto C, Potts-Thompson S, Prescott L, Taylor J. Neighborhood Deprivation, Trauma Profiles, Coping, and Stress Prospectively Predict Depressive Symptoms Among Young African American Mothers in the InterGEN Study: A Latent Class Analysis. Journal Of Racial And Ethnic Health Disparities 2025, 1-13. PMID: 40457024, DOI: 10.1007/s40615-025-02498-3.Peer-Reviewed Original ResearchYoung African American mothersNeighborhood deprivationImprove mental healthAfrican American mothersMental healthDepressive symptomsStatistically significant predictors of depressive symptomsEffect of neighborhood deprivationLatent class analysisExposure to neighbourhood deprivationSignificant predictors of depressive symptomsAmerican mothersPredictors of depressive symptomsAvoidant copingResultsIn unadjusted modelsClass analysisAfrican American womenIndividual coping skillsInterGEN StudyExperiences of traumaSocioeconomic disparitiesUnadjusted modelsPsychological supportCoping skillsCommunity strengthsPsychosocial Stressors Explaining the Monosexual–Bisexual Disparity in Mental Health: A Population-Based Study of Sexual-Minority Young Adults
Clark K, Dyar C, Bränström R, Pachankis J. Psychosocial Stressors Explaining the Monosexual–Bisexual Disparity in Mental Health: A Population-Based Study of Sexual-Minority Young Adults. Clinical Psychological Science 2025, 13: 489-505. DOI: 10.1177/21677026241286875.Peer-Reviewed Original ResearchSexual minority young adultsGeneral life stressorsMental health problemsSexual identity centralityGender of sexual partnersMental healthBisexual peopleBisexual respondentsGender conformityLife stressorsLatent class analysisSexual attractionBisexual subgroupsClass analysisPeople's mental healthYoung adulthoodPsychosocial stressorsSexual partnersYoung adultsGenderNonprobability samplingPopulation-based studyHealthRespondentsAnalyzed dataIdentifying subgroups of adverse childhood experiences (ACEs) in adult general hospital attendees: associations with mental and physical health measures
Saunders R, Nolte T, Osborn T, Delamain H, Riedl D, Fonagy P, Lampe A. Identifying subgroups of adverse childhood experiences (ACEs) in adult general hospital attendees: associations with mental and physical health measures. Journal Of Psychiatric Research 2025, 187: 291-298. PMID: 40408977, DOI: 10.1016/j.jpsychires.2025.05.024.Peer-Reviewed Original ResearchConceptsAdverse childhood experiencesACE clustersHealth outcomesHealth conditionsAssessment of adverse childhood experiencesCombinations of adverse childhood experiencesIncreased ACE exposurePhysical health measuresChildhood experiencesPhysical health conditionsMental health conditionsPhysical health outcomesAdult health outcomesHigh adverse childhood experiencesAustrian university hospitalLogistic regression modelsACE exposureMental healthHealth measuresSubgroups of individualsOdds ratioLatent class analysisPrevention strategiesOutpatient departmentHospital attendees[Association between dietary behavior and sarcopenia in older adults aged 65 years and above in longevity areas of China: a latent class analysis].
Zhao Y, Zhang Z, Wang J, Zhou J, Chen H, Qi L, Li Y, Chen Y, Meng X, Zhang Z, Chen C, Shi X, Lyu Y, Shi W. [Association between dietary behavior and sarcopenia in older adults aged 65 years and above in longevity areas of China: a latent class analysis]. Chinese Journal Of Epidemiology 2025, 46: 746-752. PMID: 40494780, DOI: 10.3760/cma.j.cn112338-20241117-00729.Peer-Reviewed Original ResearchConceptsDietary behaviorsOlder adultsCategory scoresLatent class analysisDietary intakeFood intake frequencyRisk of sarcopeniaIncreased riskBalanced dietary patternFood frequency questionnaireIntake of cerealsMultivariate logistic regression modelChronic disease historyNon-sarcopenia groupLogistic regression modelsClass analysisIntake categoriesSARC-CalF.Frequency questionnaireBiomarkers Cohort StudyIntake frequencyDietary patternsSarcopenia groupCohort studyLongevity areasEpigenetic and genetic profiling of comorbidity patterns among substance dependence diagnoses
Pathak G, Pietrzak R, Lacobelle A, Overstreet C, Wendt F, Deak J, Friligkou E, Nunez Y, Montalvo-Ortiz J, Levey D, Kranzler H, Gelernter J, Polimanti R. Epigenetic and genetic profiling of comorbidity patterns among substance dependence diagnoses. Molecular Psychiatry 2025, 1-9. PMID: 40247127, DOI: 10.1038/s41380-025-03031-y.Peer-Reviewed Original ResearchSubstance dependence diagnosesLatent class analysisDependence diagnosisLatent classesComorbidity patternsPolygenic scoresPolygenic overlapSD diagnosisPsychosocial traitsEpigenetic mechanismsClass analysisEpigenome-wide significant associationsEpigenome-wide association analysisCo-occurrenceTraitsIndividualsAssociated with CpG sitesAssociationComorbidityTDSD patternSubstancesEpigenome-wide changesIndividuals of European descentSignificant associationPerfect health not so perfect after all – a methodological study on patient-reported outcome measures in 2574 patients following percutaneous coronary intervention
Norekvål T, Iversen M, Oterhals K, Allore H, Borregaard B, Pettersen T, Thompson D, Zwisler A, Breivik K. Perfect health not so perfect after all – a methodological study on patient-reported outcome measures in 2574 patients following percutaneous coronary intervention. Health And Quality Of Life Outcomes 2025, 23: 35. PMID: 40188074, PMCID: PMC11972467, DOI: 10.1186/s12955-025-02360-4.Peer-Reviewed Original ResearchConceptsMyocardial Infarction Dimensional Assessment ScaleEQ-5D-5L scoresPatient-reported outcome measuresEQ-5D-5LCeiling effectsOutcome measuresDaily life challengesPicture of patients' health statusHealth statusDisease-specific patient-reported outcome measuresPatient healthBackgroundPatient-reported outcome measuresLatent class analysisHealth utility instrumentsSelf-reported healthPercutaneous coronary interventionPercutaneous coronary intervention centreDisease-specific instrumentPatients' health statusSide effects of medicationsLife challengesEQ-5D-5L descriptive systemSymptoms of fatigueCoronary artery diseaseClass analysis249 Patterns of Complementary and Integrative Health Therapy Utilization Among Veterans on Long-Term Opioid Therapy: A Latent Class Analysis
Kazemitabar M, Becker W, Zeliadt S, Abel E, Rajeevan H, Kerns R, Black A. 249 Patterns of Complementary and Integrative Health Therapy Utilization Among Veterans on Long-Term Opioid Therapy: A Latent Class Analysis. Journal Of Pain 2025, 29: 105047. DOI: 10.1016/j.jpain.2025.105047.Peer-Reviewed Original ResearchFunctional Trajectories After COVID‐19 Hospitalization Among Older Adults
Ho J, McAvay G, Murphy T, Acampora D, Araujo K, Geda M, Gill T, Hajduk A, Cohen A, Ferrante L. Functional Trajectories After COVID‐19 Hospitalization Among Older Adults. Journal Of The American Geriatrics Society 2025, 73: 1733-1741. PMID: 40096163, PMCID: PMC12213203, DOI: 10.1111/jgs.19420.Peer-Reviewed Original ResearchConceptsIn-hospital deliriumFunction trajectoriesFactors associated with trajectory membershipTrajectory membershipAssociation of potential risk factorsCommunity-dwelling adultsRisk factorsModifiable risk factorsMedical decision-makingOlder survivorsPotential risk factorsOlder AdultsSeverity of illnessAssociated with membershipYears of ageCOVID-19 hospitalizationModerate trajectoryLatent class analysisMultinomial regressionSurvive hospitalizationCOVID-19DisabilitySeverity trajectoriesHospitalClass analysisPolypharmacy and its association with dementia, Parkinson’s disease, and mortality risk in UK adults: a multistate modeling approach
Weiss J, Beydoun M, Georgescu M, Maldonado A, Beydoun H, Noren Hooten N, Tsai J, Song M, Nieva A, Evans M, Zonderman A. Polypharmacy and its association with dementia, Parkinson’s disease, and mortality risk in UK adults: a multistate modeling approach. GeroScience 2025, 47: 4349-4367. PMID: 40080299, PMCID: PMC12181516, DOI: 10.1007/s11357-025-01586-w.Peer-Reviewed Original ResearchConceptsHealth transitionOlder adultsCardiovascular healthLatent class analysisUK Biobank participantsRisks associated with polypharmacyHealth statesAssociated with dementiaPopulation-based cohortAssociated with higher riskYears of follow-upMedication combinationsClass analysisBiobank participantsHealth outcomesPolypharmacy statusPolypharmacy prevalenceSocioeconomic statusUK adultsMortality riskDementiaParkinson's diseasePolypharmacyHealthAdverse outcomesObservational and Genetic Analyses of Traumatic Experiences and Endometriosis
Koller D, Løkhammer S, Goroshchuk O, Denner V, Stiltner B, Mitjans M, He J, Taylor H, Lawn R, Koenen K, Polimanti R. Observational and Genetic Analyses of Traumatic Experiences and Endometriosis. JAMA Psychiatry 2025, 82: 386-394. PMID: 39908042, PMCID: PMC11800128, DOI: 10.1001/jamapsychiatry.2024.4694.Peer-Reviewed Original ResearchPolygenic risk scoresLatent class analysisAssociated with increased oddsTraumatic experiencesImpact of childhoodIndividual-level dataCase-control studyStressful eventsGenetic predispositionTrauma-related outcomesUnaffected womenMain OutcomesFinnGen cohortRisk scoreAssociation of endometriosisPosttraumatic stress disorderTrauma eventsMeta-analysisSexual traumaAssociated with endometriosisContact traumaPotential associationStress disorderPsychological traumaPhenotypic associations
2024
Identifying transdiagnostic traumatic stress reactions in U.S. military veterans: A nationally representative study
Pugach C, Adams S, Wisco B, Pietrzak R. Identifying transdiagnostic traumatic stress reactions in U.S. military veterans: A nationally representative study. Journal Of Traumatic Stress 2024, 38: 259-271. PMID: 39682069, PMCID: PMC11967292, DOI: 10.1002/jts.23119.Peer-Reviewed Original ResearchPosttraumatic stress disorderTraumatic stress reactionsU.S. military veteransDysphoric arousalMilitary veteransSelf-reported posttraumatic stress disorderPosttraumatic stress disorder symptomsNational Health and ResilienceStress reactionsComorbid psychopathologyPsychopathological symptomsGeneralized anxietyStress disorderDiagnostic subtypesVeterans StudyDepressive symptomsLatent class analysisTrauma historySymptom differencesU.S. veteransPsychopathologyMental functioningPsychosocial correlatesArousalFunctional impairmentLabor and delivery unit practices and racial and ethnic disparities in severe maternal and neonatal morbidity among nulliparous individuals with low-risk pregnancies
Leonard S, Xu X, Davies-Balch S, Main E, Bateman B, Rehkopf D, Lee H, Illuzzi J, Igbinosa I, Iwekaogwu I, Lyell D. Labor and delivery unit practices and racial and ethnic disparities in severe maternal and neonatal morbidity among nulliparous individuals with low-risk pregnancies. American Journal Of Epidemiology 2024, kwae459. PMID: 39691947, DOI: 10.1093/aje/kwae459.Peer-Reviewed Original ResearchLow-risk pregnanciesEthnic disparitiesUnit practicesAI/AN individualsNulliparous individualsNeonatal morbidityDisparity measuresAlaska NativesDelivery unitLatino individualsSevere neonatal morbidityWhite individualsLatent class analysisG-estimationSurvey responsesDisparitiesHospitalClass analysisMorbidityDeliveryIndividualsPracticeBirthPregnancyAI/ANDistinct comorbidity phenotypes among post‐9/11 Veterans with epilepsy are linked to diverging outcomes and mortality risks
Pugh M, Clary H, Myers M, Kennedy E, Amuan M, Swan A, Hinds S, LaFrance W, Altalib H, Towne A, Henion A, White A, Baca C, Wang C. Distinct comorbidity phenotypes among post‐9/11 Veterans with epilepsy are linked to diverging outcomes and mortality risks. Epilepsia 2024, 66: 170-183. PMID: 39487827, PMCID: PMC11742646, DOI: 10.1111/epi.18170.Peer-Reviewed Original ResearchVeterans Health AdministrationCause of deathService membersLatent class analysisPost-9/11 service membersVeterans receiving careContinuity of careInterdisciplinary health teamComorbid phenotypesPost-9/11 veteransOverall patient careMitigate adverse outcomesHealth teamsEpilepsy diagnosisAssociated with mortalityHealth trajectoriesHealth AdministrationPatient carePost-traumatic stress disorderMortality outcomesDescriptive statisticsAnnual diagnosesChronic diseasesNational cohortMortality riskIndividual and social-environmental factors among young drivers informing decisions to ride with an impaired driver and drive impaired: A sequential mixed methods assessment
Vaca F, Camenga D, Li K, Zuniga V, Banz B, Iannotti R, Grayton C, Simons-Morton B, Haynie D, Curry L. Individual and social-environmental factors among young drivers informing decisions to ride with an impaired driver and drive impaired: A sequential mixed methods assessment. Traffic Injury Prevention 2024, 25: s15-s24. PMID: 39485697, PMCID: PMC11563878, DOI: 10.1080/15389588.2024.2368595.Peer-Reviewed Original ResearchInterview transcriptsHealth-related quality of lifeLongitudinal nationally representative studyMixed methods assessmentHealth-related qualityQualitative interview guideSequential explanatory mixed methods approachNEXT Generation Health StudyExplanatory mixed methods approachNationally representative studySocial environmental factorsStage 1 findingsAssessment of impairmentQuality of lifeMixed methods approachHealth StudyInterview guideData immersionJoint displaysMeasures of resilienceQualitative interviewsLatent class analysisRepresentative studyQualitative dataImpaired driversElucidating Heterogeneity of Intimate Partner Violence Among Women: Latent Class Analysis of Daily IPV, PTSD, and Substance Use Collected via Experience Sampling Methodologies.
Chiaramonte D, Schick M, Woerner J, Hernandez A, Sullivan T. Elucidating Heterogeneity of Intimate Partner Violence Among Women: Latent Class Analysis of Daily IPV, PTSD, and Substance Use Collected via Experience Sampling Methodologies. Journal Of Interpersonal Violence 2024, 8862605241286026. PMID: 39445476, DOI: 10.1177/08862605241286026.Peer-Reviewed Original ResearchIntimate partner violenceIntimate partner violence typesExperience intimate partner violenceLatent class analysisPartner violenceSubstance useSexual intimate partner violenceIntimate partner violence experiencesWomen’s lived experiencesCross-sectional survey dataWomen's daily livesHeterogeneity of experiencesPhysical health outcomesMicro-longitudinal dataPTSD-related distressPolicy implicationsSurvey dataMultilevel analysisAssociated with heightened riskClass analysisLived experienceViolenceDevelopment of interventionsHealth outcomesHeightened riskPatterns of Intimate Partner Violence Among Veterans: A Latent Class Analysis.
Portnoy G, Relyea M, Webermann A, Presseau C, Iverson K, Brandt C, Haskell S. Patterns of Intimate Partner Violence Among Veterans: A Latent Class Analysis. Journal Of Interpersonal Violence 2024, 8862605241284087. PMID: 39394718, DOI: 10.1177/08862605241284087.Peer-Reviewed Original ResearchBidirectional intimate partner violenceIntimate partner violencePatterns of intimate partner violenceIntimate partner violence patternsLatent class analysisPartner violenceIntimate partner violence classPost-9/11 veteransPsychological intimate partner violenceSample of post-9/11 veteransClass analysisIntimate partner violence useWitnessing family violenceGender differencesClass membershipFamily violenceIPV screeningLatent class analysis modelPhysical assaultChild abuseRelationship healthViolenceEmployment statusMarital statusPotential gender differencesTypologies of Psychiatric Diagnoses Among Inpatients with Recent Suicide Attempts
Lord K, Tolin D, Diefenbach G. Typologies of Psychiatric Diagnoses Among Inpatients with Recent Suicide Attempts. Archives Of Suicide Research 2024, ahead-of-print: 1-16. PMID: 39302084, DOI: 10.1080/13811118.2024.2405732.Peer-Reviewed Original ResearchLatent class analysisSuicide attemptsComorbidity classesBattery of self-report measuresComorbidity of psychiatric disordersSemi-structured diagnostic interviewHistory of suicide attemptsPerson-centered statistical approachPatterns of comorbiditySelf-report measuresSuicide risk assessmentSuicide risk factorsDiagnostic heterogeneityDiagnostic InterviewCognitive-affectivePsychiatric disordersSuicidal ideationPsychiatric diagnosingPsychiatric multimorbidityAttempted suicideInterrupted attemptsActual attemptsSuicideComorbidityClass analysisPain, Substance Use Disorders, Mental Health, and Buprenorphine Treatment among Patients With and Without HIV
Miller E, McGinnis K, Edelman E, Feinberg T, Gordon K, Kerns R, Marshall B, Patterson J, McRae M. Pain, Substance Use Disorders, Mental Health, and Buprenorphine Treatment among Patients With and Without HIV. AIDS And Behavior 2024, 28: 3994-4004. PMID: 39264485, PMCID: PMC11586311, DOI: 10.1007/s10461-024-04494-w.Peer-Reviewed Original ResearchMental health classesSubstance use disordersOpioid use disorderHIV statusBuprenorphine initiationVeterans Aging Cohort StudyInitiate buprenorphineMental health diagnosesAging Cohort StudyBuprenorphine treatmentMultiple pain conditionsAssociated with HIV statusInfluence treatment retentionUse disorderTreatment of opioid use disorderHigher comorbidity burdenAge of patientsClinical encountersMental healthHealth diagnosisBlack veteransHealth classesLatent class analysisCohort studyPrescription dataPatterns of Family Conflict and Accusations of Abuse in Dementia Family Caregivers: A Latent Class Analysis
Browning W, Yildiz M, Maxwell C, Sullivan T, Yefimova M, Chilatra J, Pickering C. Patterns of Family Conflict and Accusations of Abuse in Dementia Family Caregivers: A Latent Class Analysis. The Gerontologist 2024, 64: gnae108. PMID: 39166288, PMCID: PMC11446213, DOI: 10.1093/geront/gnae108.Peer-Reviewed Original ResearchLatent class analysisFamily conflictNeglectful behaviorsNon-traditional family structuresGroup membershipClass analysisNon-traditional caregiversRelationship typesFamily caregiversAdult childrenFour-class solutionFamily structureMultinomial logistic regressionProbability of abuseAccusations of abuseConflictUnique risk factorsAccusationsAbuseMembershipDementia family caregiversNeglectCaregiversElevated probabilityFamilyMultimorbidity and associated informal care receiving characteristics for US older adults: a latent class analysis
Liu R, Nagel C, Chen S, Newsom J, Allore H, Quiñones A. Multimorbidity and associated informal care receiving characteristics for US older adults: a latent class analysis. BMC Geriatrics 2024, 24: 571. PMID: 38956501, PMCID: PMC11221032, DOI: 10.1186/s12877-024-05158-z.Peer-Reviewed Original ResearchConceptsNational Health and Aging Trends StudyMultimorbidity patternsCare needsOlder adultsSelf-careInformal careLatent class analysisCare receiver characteristicsCombinations of multimorbidityPerson-centered carePatterns of multimorbidityDifferential care needsUS older adultsAssociated with lower oddsAssociated with higher oddsGroup of older adultsMultinomial logistic regression modelModerate cognitive impairmentClass analysisLogistic regression modelsInformal caregiversBackgroundOlder adultsCare recipientsMultimorbidity groupsChronic conditions
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