2025
Diverging paths: Identifying barriers to and increasing accessibility of a survivorship program in a socio-economically diverse community.
Thau F, Madrid K, Smith N, Gambaccini M, Sanft T, Capozza S. Diverging paths: Identifying barriers to and increasing accessibility of a survivorship program in a socio-economically diverse community. Journal Of Clinical Oncology 2025, 43 DOI: 10.1200/jco.2025.43.16_suppl.e13877.Peer-Reviewed Original ResearchMedian household incomeSurvivorship programsClinical sitesHousehold incomeSurvivorship clinic visitLife of cancer survivorsNo-showLow median household incomePatient's zip codeIn-person visitsArea of residenceDiverse patient groupsElectronic medical recordsScheduled patient visitsState-based insuranceDiverse patient populationsCancer survivorsIdentified barriersHome addressPatient visitsScheduling appointmentsZip codesIn-personQualitative studyDemographics of patientsGenetics and family history in a diverse cohort of females with early-onset breast cancer.
Shroff T, Proussaloglou E, Namboodiri A, Gross L, Gong G, Wei W, Giri V. Genetics and family history in a diverse cohort of females with early-onset breast cancer. Journal Of Clinical Oncology 2025, 43: 10613-10613. DOI: 10.1200/jco.2025.43.16_suppl.10613.Peer-Reviewed Original ResearchEarly-onset breast cancerFamily historyGenetic testingEarly-onset breast cancer riskFamily history of breast cancerClinical careFamily history of cancerHistory of breast cancerFamily history of breastDiverse cohortBreast cancerCancer genetics programPrevalence of pathogenic/likely pathogenic variantsWhite patientsGermline genetic testingDiverse racial/ethnic populationsGenetic test resultsComprehensive cancer centerBreast cancer susceptibility genesElectronic medical recordsCancer predisposition genesAshkenazi Jewish ancestryDiverse patient populationsCancer susceptibility genesDiverse cohort of patientsPredicting Agitation Events in the Emergency Department Through Artificial Intelligence
Wong A, Sapre A, Wang K, Nath B, Shah D, Kumar A, Faustino I, Desai R, Hu Y, Robinson L, Meng C, Tong G, Bernstein S, Yonkers K, Melnick E, Dziura J, Taylor R. Predicting Agitation Events in the Emergency Department Through Artificial Intelligence. JAMA Network Open 2025, 8: e258927. PMID: 40332935, PMCID: PMC12059975, DOI: 10.1001/jamanetworkopen.2025.8927.Peer-Reviewed Original ResearchConceptsED visitsEmergency departmentAgitation eventsElectronic health record dataArea under the receiver operating characteristic curvePatient-centered careHealth service utilizationPrimary outcomeHealth record dataUrban health systemED visit dataMode of arrivalPrevention of agitationOutcome of agitationDiverse patient populationsRestraint ordersCross-sectional cohortService utilizationVital signsED sitesHealth systemMain OutcomesRestraint eventsRange of predicted probabilitiesVisit dataSafety of Stimulants Across Patient Populations
Oliva H, Prudente T, Mayerson T, Mignosa M, Oliva I, Potenza M, Jegede O, Angarita G. Safety of Stimulants Across Patient Populations. JAMA Network Open 2025, 8: e259492. PMID: 40343695, PMCID: PMC12065045, DOI: 10.1001/jamanetworkopen.2025.9492.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderRandomized clinical trialsAdverse eventsStimulant medicationData extractionSafety of stimulationRisk ratioIncreased riskMethodological quality assessmentPreferred Reporting ItemsPatient populationClinical conditionsDiverse patient populationsRisk of biasSafety of stimulant medicationsUnclear risk of biasTreatment of attention-deficit/hyperactivity disorderOverall AEsRandom-effects modelWeb of ScienceBinge eating disorderStimulant use disorderComprehensive literature searchMain OutcomesReporting Items16 Resource Allocation: Costs and Length of Stay for Non-Burn Patient in Burn Center
Usman M, Savetamal A. 16 Resource Allocation: Costs and Length of Stay for Non-Burn Patient in Burn Center. Journal Of Burn Care & Research 2025, 46: s13-s14. PMCID: PMC11958293, DOI: 10.1093/jbcr/iraf019.016.Peer-Reviewed Original ResearchNon-burn patientsLength of stayDiverse patient populationsBurn patientsPatient populationBurn centerNecrotizing soft tissue infectionStevens-Johnson syndrome/toxic epidermal necrolysisSoft tissue infectionsEnhance patient outcomesHigh-level careElectronic medical recordsBurn care settingNon-burn injuryHigh-quality treatmentSoft tissue injuriesCare settingsSoft tissue pathologyCare efficiencyTissue infectionsStratify patientsHospital stayFournier's gangreneEpidermal necrolysisRetrospective analysisParallel Detection of Multicontrast MRI and Deuterium Metabolic Imaging for Time-efficient Characterization of Neurologic Diseases.
Liu Y, De Feyter H, Corbin Z, Fulbright R, McIntyre S, Nixon T, de Graaf R. Parallel Detection of Multicontrast MRI and Deuterium Metabolic Imaging for Time-efficient Characterization of Neurologic Diseases. Radiology 2025, 315: e241597. PMID: 40197096, DOI: 10.1148/radiol.241597.Peer-Reviewed Original ResearchConceptsDeuterium metabolic imagingMRI protocolMetabolic imagingDecrease patient complianceUnique metabolic informationClinical MRI protocolsIn vivo human brain dataMRI examinationsMetabolism scansPatient compliancePatient populationNoninvasively in vivoDiverse patient populationsMRI-based methodMRIClinical sitesLong scan timesMetabolic informationScan qualityHuman brain dataNeurological diseasesImage contrastScan durationClinical MRIMulticontrast MRICorrection: Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications and CBT4CBT: protocol for a randomized clinical trial in a diverse patient population
Edelman E, Rojas-Perez O, Nich C, Corvino J, Frankforter T, Gordon D, Jordan A, Paris, Jr M, Weimer M, Yates B, Williams E, Kiluk B. Correction: Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications and CBT4CBT: protocol for a randomized clinical trial in a diverse patient population. Addiction Science & Clinical Practice 2025, 20: 29. PMID: 40128914, PMCID: PMC11931771, DOI: 10.1186/s13722-025-00558-x.Peer-Reviewed Original ResearchObjectifying aesthetic outcomes following face transplantation – the AI research metrics model (CAARISMA ® ARMM)
Knoedler L, Hoch C, Knoedler S, Klimitz F, Schaschinger T, Niederegger T, Heiland M, Koerdt S, Pooth R, Kauke-Navarro M, Lellouch A. Objectifying aesthetic outcomes following face transplantation – the AI research metrics model (CAARISMA ® ARMM). Journal Of Stomatology Oral And Maxillofacial Surgery 2025, 126: 102277. PMID: 39947010, DOI: 10.1016/j.jormas.2025.102277.Peer-Reviewed Original ResearchFacial Aesthetic IndexAesthetic outcomesFT patientsFace transplantationAesthetic IndexAesthetic improvementPatient-surgeon communicationSevere facial disfigurementEnhance surgical planningNo significant differenceFacial aestheticsPreoperative scoresPostoperative scoresSurgical planningReconstructive optionsPatient populationDiverse patient populationsPatientsMetric modelFacial disfigurementSignificant differenceAesthetic successTime pointsTransplantationOutcomes
2024
TARGET: A Randomized, Noninferiority Trial of a Pretest, Patient-Driven Genetic Education Webtool Versus Genetic Counseling for Prostate Cancer Germline Testing
Loeb S, Keith S, Cheng H, Leader A, Gross L, Nolasco T, Byrne N, Hartman R, Brown L, Pieczonka C, Gomella L, Kelly W, Lallas C, Handley N, Mille P, Mark J, Brown G, Chopra S, McClellan A, Wise D, Hollifield L, Giri V. TARGET: A Randomized, Noninferiority Trial of a Pretest, Patient-Driven Genetic Education Webtool Versus Genetic Counseling for Prostate Cancer Germline Testing. JCO Precision Oncology 2024, 8: e2300552. PMID: 38452310, PMCID: PMC10939575, DOI: 10.1200/po.23.00552.Peer-Reviewed Original ResearchConceptsGermline genetic testingDecisional conflictGenetic counselingProstate cancerPatient-drivenShortage of genetic counselorsKnowledge of cancer geneticsHereditary cancer riskReduce decisional conflictDecisional Conflict ScalePrimary outcome dataMixed-effects regression modelsDiverse patient populationsGenetic servicesClinical trial eligibilityGenetic counselorsGenetics educationPatient experienceCancer riskGermline testingAnalytical data setsCancer geneticsGermline evaluationConflict ScaleGenetic testingDisinfection of central venous access device needleless connectors: A human factors analysis
Drews F, Martinello R, Hebden J, St. John K, Pegues D. Disinfection of central venous access device needleless connectors: A human factors analysis. Infection Control And Hospital Epidemiology 2024, 45: 959-964. PMID: 38389492, DOI: 10.1017/ice.2024.22.Peer-Reviewed Original ResearchCentral line-associated bloodstream infectionsNurse focus groupsIntensive care unitCentral venous access devicesMixed-methods studyObservations of complianceAcademic medical centerDiverse patient populationsPerceived facilitatorsRisk of central line-associated bloodstream infectionsGuideline noncomplianceOngoing educationKnowledge deficitsPrevention guidelinesHigh workloadMedical CenterRecommended timeIsopropyl alcohol wipesVenous access devicesCare unitLess workloadCompetency evaluationPatient populationFacilitationAntiseptic scrubPragmatic randomized controlled trials: strengthening the concept through a robust international collaborative network: PRIME-9—Pragmatic Research and Innovation through Multinational Experimentation
Omerovic E, Petrie M, Redfors B, Fremes S, Murphy G, Marquis-Gravel G, Lansky A, Velazquez E, Perera D, Reid C, Smith J, van der Meer P, Lipsic E, Juni P, McMurray J, Bauersachs J, Køber L, Rouleau J, Doenst T. Pragmatic randomized controlled trials: strengthening the concept through a robust international collaborative network: PRIME-9—Pragmatic Research and Innovation through Multinational Experimentation. Trials 2024, 25: 80. PMID: 38263138, PMCID: PMC10807265, DOI: 10.1186/s13063-024-07935-y.Peer-Reviewed Original ResearchConceptsRandomized controlled trialsValue-based health careHealth policy decision-makingResearch priority settingQuality of healthcareHealthcare delivery systemValue-based healthcareDiverse practice settingsEffectiveness of interventionsPragmatic clinical trialsDiverse patient populationsPublic health impactEvidence-based medicineHealthcare qualityHealth outcomesHealth careHealthcare settingsDecision-making questionsPractice settingsPriority settingDecision-makingAlternative interventionsHealthcareStudy designPRCTsSurvey Protocols, Response Rates, and Representation of Underserved Patients
Elliott M, Brown J, Hambarsoomian K, Parast L, Beckett M, Lehrman W, Giordano L, Goldstein E, Cleary P. Survey Protocols, Response Rates, and Representation of Underserved Patients. JAMA Health Forum 2024, 5: e234929. PMID: 38241055, PMCID: PMC10799262, DOI: 10.1001/jamahealthforum.2023.4929.Peer-Reviewed Original ResearchConceptsHospital Consumer Assessment of Healthcare Providers and SystemsOther Pacific IslanderDiverse patient populationsMultiracial patientsPatient surveyConsumer Assessment of Healthcare Providers and SystemsAssessment of Healthcare Providers and SystemsHealthcare Providers and SystemsCenters for Medicare & Medicaid ServicesRandomized clinical trialsUS Centers for Medicare & Medicaid ServicesWhite patientsResponse rateQuality improvement effortsService linesPacific Islander patientsSurvey protocolPacific IslandersPatient populationIslander patientsPatient-importantUnderserved patient groupsMedicaid ServicesAlaska NativesMain Outcomes
2023
The impact of neighborhoods and friendships on interracial anxiety among medical students and residents: A report from the medical student CHANGES study
Plaisime M, Jipguep‐Akhtar M, Locascio J, Belcher H, Hardeman R, Picho‐Kiroga K, Perry S, Phelan S, van Ryn M, Dovidio J. The impact of neighborhoods and friendships on interracial anxiety among medical students and residents: A report from the medical student CHANGES study. Health Services Research 2023, 58: 229-237. PMID: 37312013, PMCID: PMC10339166, DOI: 10.1111/1475-6773.14191.Peer-Reviewed Original ResearchRacial and Ethnic Disparities in Outcomes Among Newborns with Congenital Diaphragmatic Hernia
Sferra S, Salvi P, Penikis A, Weller J, Canner J, Guo M, Engwall-Gill A, Rhee D, Collaco J, Keiser A, Solomon D, Kunisaki S. Racial and Ethnic Disparities in Outcomes Among Newborns with Congenital Diaphragmatic Hernia. JAMA Network Open 2023, 6: e2310800. PMID: 37115544, PMCID: PMC10148194, DOI: 10.1001/jamanetworkopen.2023.10800.Peer-Reviewed Original ResearchConceptsAssociated with lower mortalityCongenital diaphragmatic herniaHispanic patientsPatient raceCohort studyWhite patientsBlack infantsLower mortalityPediatric Health Information System databaseEthnically diverse patient populationIn-hospitalHealth Information System databaseUS children's hospitalsEthnically diverse populationsDiverse patient populationsInstitutional-level factorsDiaphragmatic herniaInformation System databaseEthnic disparitiesMain OutcomesGuardian reportIn-hospital mortalityMortality differencesExtracorporeal life support useChildren's hospital
2022
Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors
Nassar AH, Adib E, Abou Alaiwi S, El Zarif T, Groha S, Akl EW, Nuzzo PV, Mouhieddine TH, Perea-Chamblee T, Taraszka K, El-Khoury H, Labban M, Fong C, Arora KS, Labaki C, Xu W, Sonpavde G, Haddad RI, Mouw KW, Giannakis M, Hodi FS, Zaitlen N, Schoenfeld AJ, Schultz N, Berger MF, MacConaill LE, Ananda G, Kwiatkowski DJ, Choueiri TK, Schrag D, Carrot-Zhang J, Gusev A. Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors. Cancer Cell 2022, 40: 1161-1172.e5. PMID: 36179682, PMCID: PMC9559771, DOI: 10.1016/j.ccell.2022.08.022.Peer-Reviewed Original ResearchConceptsTumor mutational burdenImproved outcomesMutational burdenSolid tumorsNon-small cell lung cancerImmune checkpoint inhibitor pembrolizumabHigh tumor mutational burdenCheckpoint inhibitor pembrolizumabTMB-high groupImmune checkpoint inhibitorsCell lung cancerDisparate clinical outcomesDiverse patient populationsCheckpoint inhibitorsClinical outcomesPatient populationLung cancerClinical cohortAccurate biomarkersUS FDATumorsBiomarker studiesNon-European ancestry populationsPrecision medicinePatientsDiversity in clinical research: public health and social justice imperatives
Varma T, Jones CP, Oladele C, Miller J. Diversity in clinical research: public health and social justice imperatives. Journal Of Medical Ethics 2022, 49: 200-203. PMID: 35428737, DOI: 10.1136/medethics-2021-108068.Peer-Reviewed Original Research
2021
Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection
McPadden J, Warner F, Young HP, Hurley NC, Pulk RA, Singh A, Durant TJS, Gong G, Desai N, Haimovich A, Taylor RA, Gunel M, Dela Cruz CS, Farhadian SF, Siner J, Villanueva M, Churchwell K, Hsiao A, Torre CJ, Velazquez EJ, Herbst RS, Iwasaki A, Ko AI, Mortazavi BJ, Krumholz HM, Schulz WL. Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection. PLOS ONE 2021, 16: e0243291. PMID: 33788846, PMCID: PMC8011821, DOI: 10.1371/journal.pone.0243291.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionYale New Haven HealthSARS-CoV-2Hospital mortalityRisk of admissionMale sexRisk factorsSARS-CoV-2 testingInvasive mechanical ventilationSevere acute respiratory syndrome virusBurden of diseaseRT-PCR testingAcademic health systemDiverse patient populationsRespiratory syndrome virusEthnic groupsAdult patientsClinical characteristicsDischarge dispositionRespiratory supportPrimary outcomeTreatment guidelinesMechanical ventilationRetrospective studyPatient population
2020
Looking Beyond the Numbers: Increasing Diversity and Inclusion Through Holistic Review in General Surgery Recruitment
Nehemiah A, Roberts SE, Song Y, Kelz RR, Butler PD, Morris JB, Aarons CB. Looking Beyond the Numbers: Increasing Diversity and Inclusion Through Holistic Review in General Surgery Recruitment. Journal Of Surgical Education 2020, 78: 763-769. PMID: 32950431, DOI: 10.1016/j.jsurg.2020.08.048.Peer-Reviewed Original ResearchConceptsProportion of womenGeneral surgery residency programsSurgery residency programsDiverse patient populationsResidency programsRetrospective studyPatient populationSubgroup analysisABSITE scoresCategorical positionAcademic centersUnited States Medical Licensing Exam scoresWomenCategorical internsIntern classScoresSignificant increaseRecruitment of womenUIM applicantsResidency trainingAmerican BoardUIM studentsNational medianPivotal roleTraining exam scoresLong-Term Financial, Psychosocial, and Overall Health-Related Quality of Life After Living Liver Donation
Raza M, Kim M, Ding L, Fong T, Romero C, Genyk Y, Sher L, Emamaullee J. Long-Term Financial, Psychosocial, and Overall Health-Related Quality of Life After Living Liver Donation. Journal Of Surgical Research 2020, 253: 41-52. PMID: 32320896, PMCID: PMC8351216, DOI: 10.1016/j.jss.2020.03.025.Peer-Reviewed Original ResearchConceptsHealth-related quality of lifeHealth-related qualityQuality of lifeHRQoL outcomesU.S. population normsShort Form-36Quality of Life SurveyFollow-upDiverse patient populationsPhysical activityHealthy potential donorsPopulation normsLiving liver donorsShort formHealth insuranceLifetime follow-upU.S. populationQuality of Life Survey dataLife SurveyAging populationLiver donationPatient populationPostdonation follow-upOutcomesWork performance
2017
Biomarkers for the detection of renal fibrosis and prediction of renal outcomes: a systematic review
Mansour SG, Puthumana J, Coca SG, Gentry M, Parikh CR. Biomarkers for the detection of renal fibrosis and prediction of renal outcomes: a systematic review. BMC Nephrology 2017, 18: 72. PMID: 28219345, PMCID: PMC5319065, DOI: 10.1186/s12882-017-0490-0.Peer-Reviewed Original ResearchConceptsMatrix metalloproteinase-2Renal outcomesRenal functionRenal fibrosisStage ISystematic reviewWorse renal outcomeChronic kidney diseaseBiomarkers of fibrosisChemoattractant protein-1Diverse patient populationsGrowth factor βUrine biomarkersKidney diseaseMCP-1Patient populationDisease progressionMetalloproteinase-2FibrosisModerate positive correlationStage IIPatientsUnifying pathwayBiomarkersReliability of blood
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