2025
Linking attention bias to youth social anxiety and depression: Insights from computational modeling of the affective Posner task
Edgar E, Castagna P, Delpech R, Crowley M. Linking attention bias to youth social anxiety and depression: Insights from computational modeling of the affective Posner task. Journal Of Affective Disorders 2025, 388: 119764. PMID: 40562109, DOI: 10.1016/j.jad.2025.119764.Peer-Reviewed Original ResearchDepressive symptom severityParent-reported social anxietyAttentional biasSocial anxietySymptom severityPubertal statusFunction of pubertal statusThreat-related stimuliDrift diffusion model parametersSymptoms of psychopathologyYouth social anxietyLatent cognitive processesSymptoms of anxietyDrift diffusion parametersHigher pubertal statusPosner taskDepressive symptomatologyPredicting anxietyDepressive symptomsCognitive processesEvidence accumulationDrift rateAnxietyDepressionBehavioral dataLatent Health Status Trajectories in Individuals With New or Worsening Claudication Symptoms.
Grubman S, Romain G, Cleman J, Scierka L, Pajarillo C, Kluger J, Mena-Hurtado C, Smolderen K. Latent Health Status Trajectories in Individuals With New or Worsening Claudication Symptoms. Journal Of The American Heart Association 2025, 14: e039455. PMID: 40530482, DOI: 10.1161/jaha.124.039455.Peer-Reviewed Original ResearchConceptsHealth status trajectoriesPeripheral artery disease careStatus trajectoriesDisease careHealth statusClaudication symptomsTrajectory subgroupsPeripheral Artery QuestionnaireVascular specialty clinicsPeripheral artery questionnaire scoresHierarchical multivariable logistic regressionImprove health statusMultivariate logistic regressionClinically meaningful thresholdsRegistry of patientsPsychosocial factorsBiopsychosocial modelDepressive symptomsSpecialty clinicsAlcohol use disorderQuestionnaire scoresRecovery trajectoriesLogistic regressionHealthLatent trajectory modelsProlonged hospitalization for hematopoietic cell transplantation (HCT): Characteristics, risk factors and associations with patient-reported and clinical outcomes
Gao L, Nelson A, Barata A, Horick N, Wekwerth B, Wood A, Fernandes A, Lee S, LeBlanc T, Amonoo H, El-Jawahri A, Newcomb R. Prolonged hospitalization for hematopoietic cell transplantation (HCT): Characteristics, risk factors and associations with patient-reported and clinical outcomes. Transplantation And Cellular Therapy 2025 PMID: 40505814, DOI: 10.1016/j.jtct.2025.05.026.Peer-Reviewed Original ResearchPatient-reported outcomesProlonged length of staySymptom burdenDepressive symptomsYears post-HCTSpecialty palliative careSecondary analysis of dataHigh risk of prolonged length of stayMonths post-HCTGreater healthcare utilizationCox proportional hazards regressionIncreased risk of mortalityAssociated with higher riskQuality of lifeProportional hazards regressionMultivariate logistic regressionRisk of rehospitalizationPosttraumatic stress symptomsRisk of mortalityPalliative careRisk of prolonged length of stayAssociated with prolonged length of stayDepression burdenHealthcare utilizationLength of stayNeighborhood Deprivation, Trauma Profiles, Coping, and Stress Prospectively Predict Depressive Symptoms Among Young African American Mothers in the InterGEN Study: A Latent Class Analysis
Lane B, Millender E, Harris R, Nowak A, Josiah N, Hall C, Pfeiffer F, Wong F, Crusto C, Potts-Thompson S, Prescott L, Taylor J. Neighborhood Deprivation, Trauma Profiles, Coping, and Stress Prospectively Predict Depressive Symptoms Among Young African American Mothers in the InterGEN Study: A Latent Class Analysis. Journal Of Racial And Ethnic Health Disparities 2025, 1-13. PMID: 40457024, DOI: 10.1007/s40615-025-02498-3.Peer-Reviewed Original ResearchYoung African American mothersNeighborhood deprivationImprove mental healthAfrican American mothersMental healthDepressive symptomsStatistically significant predictors of depressive symptomsEffect of neighborhood deprivationLatent class analysisExposure to neighbourhood deprivationSignificant predictors of depressive symptomsAmerican mothersPredictors of depressive symptomsAvoidant copingResultsIn unadjusted modelsClass analysisAfrican American womenIndividual coping skillsInterGEN StudyExperiences of traumaSocioeconomic disparitiesUnadjusted modelsPsychological supportCoping skillsCommunity strengthsPsychometric properties and socio-demographic correlates of the Connor-Davidson Resilience Scale in three large population-based cohorts including Danish and Icelandic adults
Didriksen M, Daníelsdottir H, Bjarnadóttir M, Overstreet C, Choi K, Christoffersen L, Mikkelsen C, Aspelund T, Hauksdóttir A, Thordardottir E, Jakobsdóttir J, Tómasson G, Erikstrup C, Aagaard B, Bruun M, Ullum H, Sørensen E, Fischer I, Pietrzak R, Gelernter J, Campbell-Sills L, Stein M, Werge T, Pedersen O, Valdimarsdóttir U, Ostrowski S, Schork A. Psychometric properties and socio-demographic correlates of the Connor-Davidson Resilience Scale in three large population-based cohorts including Danish and Icelandic adults. Journal Of Mood And Anxiety Disorders 2025, 10: 100112. DOI: 10.1016/j.xjmad.2025.100112.Peer-Reviewed Original ResearchMeasures of psychological resilienceCD-RISC-10Connor-Davidson Resilience ScalePsychometric propertiesCD-RISC-10 scoresPsychological resilienceResilience ScalePopulation-based cohortExploratory factor analysisDepressive disorderDepressive symptomsLongitudinal stabilityInternal consistencyUnidimensional measureConstruct validitySocio-demographic correlatesFactor analysisPhysical healthLower scoresHigher scoresResilient cohortsDanish Blood Donor StudyIcelandic adultsDanish individualsBlood Donor StudyA Digital Depression Treatment Program for Adults Treated in Primary Care
Dahne J, Wahlquist A, Carpenter M, Graboyes E, Lejuez C, Kustanowitz J, Natale N, Levins O, Player M, Diaz V. A Digital Depression Treatment Program for Adults Treated in Primary Care. JAMA Internal Medicine 2025, 185: 692-701. PMID: 40227715, PMCID: PMC11997856, DOI: 10.1001/jamainternmed.2025.0494.Peer-Reviewed Original ResearchElectronic health recordsBeck Depression Inventory-IIPrimary care settingBehavioral activation interventionDepressive symptomsClinically significant improvementUsual careActivity interventionsCare settingsElectronic health record featuresElectronic health record integrationPatient Health Questionnaire-9Depression remissionModerate symptoms of depressionPrimary care providersPrimary care clinicsDepression treatment programTreating depressive symptomsSymptoms of depressionPrimary careSignificant improvementCare clinicsIntervention engagementCare providersScalable interventionsMental Health, Substance Use, and Tuberculosis Preventive Therapy in People With HIV: A Prospective Cohort Study
Johnson A, Chimoyi L, Shenoi S, Brault M, Forastiere L, Charalambous S, Chihota V, Davis J. Mental Health, Substance Use, and Tuberculosis Preventive Therapy in People With HIV: A Prospective Cohort Study. Open Forum Infectious Diseases 2025, 12: ofaf303. PMID: 40567997, PMCID: PMC12188208, DOI: 10.1093/ofid/ofaf303.Peer-Reviewed Original ResearchTuberculosis preventive therapyUnhealthy alcohol useMental healthDepressive symptomsAlcohol useTobacco useAssociation of mental healthInfluence of mental healthCohort studyMeasure symptoms of anxietyNegatively associated with adherenceDeductive content analysisMixed methods studySubstance useLongitudinal cohort studyPsychological support servicesSymptoms of anxietySymptoms of depressionPreventive therapyProspective cohort studyAntiretroviral therapyHIV mortalityMultivariate regression modelSubstance use disordersMethods studyNational Trends in Suicidal Thoughts and Suicide Attempts Among High School Students in the United States
Bommersbach T, Olfson M, Rhee T. National Trends in Suicidal Thoughts and Suicide Attempts Among High School Students in the United States. American Journal Of Psychiatry 2025, 182: 639-659. PMID: 40432341, DOI: 10.1176/appi.ajp.20240706.Peer-Reviewed Original ResearchConceptsPast-year suicidal thoughtsSuicidal thoughtsHigh school studentsHealth risk behaviorsSuicidal symptomsSuicide attemptsNon-Hispanic whitesSchool studentsBehavioral risksBlack studentsNational trendsHigh school seniorsU.S. high school studentsDepressive symptomsAttempted suicideRisk categoriesEstimate national trendsBiennial cross-sectional surveysMultivariate logistic regressionSuicideYouth Risk Behavior SurveySchool seniorsElevated ratesHealth risk categoriesRisk Behavior SurveyNon-fatal Overdose and Associated Factors Among People Who Use Opioids: Findings From a Cross-sectional Study
Sujan M, Wickersham J, Khati A, Paudel K, Gautam K, Liautaud D, Crim H, Thapa A, Copenhaver M, Shrestha R. Non-fatal Overdose and Associated Factors Among People Who Use Opioids: Findings From a Cross-sectional Study. Journal Of Community Health 2025, 1-10. PMID: 40381076, DOI: 10.1007/s10900-025-01480-8.Peer-Reviewed Original ResearchNon-fatal overdoseOpioid dependenceCross-sectional studySuicidal ideationHistory of opioid useOpioid overdoseAlcohol use disorderNon-fatal opioid overdoseMental health symptomsAge of participantsParticipants self-reportedHarm reduction interventionsSocio-demographic characteristicsOpioid useEffective prevention strategiesUse disorderDepressive symptomsTargeted harm reduction interventionsHealth symptomsMultivariate logistic regression analysisLogistic regression analysisReduction interventionsOlder participantsCross-sector collaborationRisk of overdoseLoneliness Among US Veterans With Problematic Substance Use: Results From the National Health and Resilience in Veterans Study
Na P, Pless Kaiser A, McCurdy L, Fischer I, Jeste D, Petrakis I, Potenza M, Pietrzak R. Loneliness Among US Veterans With Problematic Substance Use: Results From the National Health and Resilience in Veterans Study. Journal Of Addiction Medicine 2025 DOI: 10.1097/adm.0000000000001508.Peer-Reviewed Original ResearchProblematic substance useNational Health and ResilienceSocial network sizeCorrelates of lonelinessVeterans StudyDepressive symptomsUS veteransPsychological distressSubstance useLifetime suicide attemptsPosttraumatic stress symptomsThree-Item Loneliness ScaleUS military veteransPurpose in lifeSuicide attemptsStress symptomsPervasive public health problemBurden of lonelinessLikelihood of lonelinessMilitary veteransNationally representative sampleLoneliness ScaleMultivariate logistic regressionPublic health problemLonelinessInfluence of resilience and social support on the association between food insecurity and depressive symptoms during pregnancy: A moderated mediation model
Carandang R, Lewis J, Masters C, Ickovics J, Cunningham S. Influence of resilience and social support on the association between food insecurity and depressive symptoms during pregnancy: A moderated mediation model. Journal Of Affective Disorders 2025, 383: 435-442. PMID: 40334869, DOI: 10.1016/j.jad.2025.05.020.Peer-Reviewed Original ResearchConceptsSocial supportDepressive symptomsFood insecurityAssociation of food insecurityInfluence of food insecurityAdverse effects of food insecurityEffects of food insecurityGroup prenatal carePregnant individualsChronic food insecurityInfluence of resilienceMediation modelPrenatal careTrimester of pregnancyRisk factorsIndirect associationsModerated mediation modelAssociationInsecurityPregnancySymptomsSupportChronically foodCareIndividualsTrajectories of positive symptoms and suicidality in individuals at clinical high risk for psychosis
Deng W, MacNutt C, Addington J, Bearden C, Cadenhead K, Carrión R, Keshavan M, Mathalon D, Perkins D, Stone W, Walker E, Woods S, Cannon T. Trajectories of positive symptoms and suicidality in individuals at clinical high risk for psychosis. Journal Of Affective Disorders 2025, 384: 208-213. PMID: 40334865, DOI: 10.1016/j.jad.2025.05.023.Peer-Reviewed Original ResearchConceptsPositive symptomsClinical high riskSuicidal ideationCHR-PMeasures of suicidal ideationEarly stages of psychosisPersistence of suicidal ideationSeverity of depressive symptomsPositive symptom severityAssessment timepointsCHR-P participantsEmergence of suicidalityStages of psychosisCHR-P populationTargeted suicide prevention strategiesPsychotic disordersEarly psychosisSuicide prevention strategiesDepressive symptomsSymptom severityPsychosisIdeationDelusionsSuicideHallucinationsSafety and efficacy with esketamine in treatment-resistant depression: long-term extension study
Zaki N, Chen L, Lane R, Doherty T, Drevets W, Morrison R, Sanacora G, Wilkinson S, Young A, Lacerda A, Paik J, Popova V, Fu D. Safety and efficacy with esketamine in treatment-resistant depression: long-term extension study. The International Journal Of Neuropsychopharmacology 2025, 28: pyaf027. PMID: 40319349, PMCID: PMC12143125, DOI: 10.1093/ijnp/pyaf027.Peer-Reviewed Original ResearchConceptsTreatment-resistant depressionSustained 3Oral antidepressantNon-treatment-resistant major depressive disorderMontgomery-Asberg Depression Rating ScaleTreatment-resistant depression treatmentEsketamine nasal sprayDepression Rating ScaleMajor depressive disorderLong-term extension studySafety of esketamineLong-term safetyRate of relapseMontgomery-AsbergDepressive disorderDepression severityEsketamine dosesExtension studySuicide riskDepressive symptomsEsketamineRating ScaleMaintenance treatmentAdverse eventsLong-term treatmentMultimorbidity patterns and cognitive change among Mexican older adults: findings from the Mexican Health and Aging Study
Bishop N, Botoseneanu A, Newsom J, Allore H, Nagel C, Markwardt S, Samper-Ternent R, Quiñones A. Multimorbidity patterns and cognitive change among Mexican older adults: findings from the Mexican Health and Aging Study. Journal Of Global Ageing 2025, 2: 65-97. DOI: 10.1332/29767202y2024d000000019.Peer-Reviewed Original ResearchMexican Health and Aging StudyHealth and Aging StudyMultimorbidity patternsMexican adultsChronic conditionsOlder adultsIncreasing burden of chronic conditionsDepressive symptomsBurden of chronic conditionsCo-occurring chronic conditionsCognitive declineCognitive functionAssociated with lower cognitive functionOlder Mexican adultsMexican older adultsRisk of cognitive declineAging StudyLower cognitive functionCognitive changesManagement of diabetesMultimorbidityIncreasing burdenCognitive trajectoriesLatent growth modelingOlder adulthoodExamining the Impact of Social Connectedness on Depression and Suicide Ideation Among Black Youth Experiencing Discrimination: A Path Analysis
Smith B, Boyd D, Quinn C. Examining the Impact of Social Connectedness on Depression and Suicide Ideation Among Black Youth Experiencing Discrimination: A Path Analysis. Journal Of Racial And Ethnic Health Disparities 2025, 1-11. PMID: 40237954, DOI: 10.1007/s40615-025-02414-9.Peer-Reviewed Original ResearchEffects of everyday discriminationSuicidal ideationDepressive symptomsEveryday discriminationSocial connectednessStress buffering modelPath analysisExperiences of racial discriminationBehavioral health outcomesSample self-identifiedIdeationAdverse behavioral health outcomesBlack youthPsychosocial stressBehavioral health practicesDepressionSuicideBuffer modelIndirect effectsRacial discriminationSupport theoryExperienced discriminationSymptomsSocial support theoryImpact of social connectednessEmotion Regulation, Depressive Symptoms, and Sleep Problems in Adolescents: A Four-Wave Random-Intercept Cross-Lagged Panel Model
Liu S, Ying J, Feng A, Shi Q, Joormann J. Emotion Regulation, Depressive Symptoms, and Sleep Problems in Adolescents: A Four-Wave Random-Intercept Cross-Lagged Panel Model. Journal Of Psychopathology And Clinical Science 2025 PMID: 40232758, DOI: 10.1037/abn0001006.Peer-Reviewed Original ResearchRandom intercept cross-lagged panel modelCross-lagged panel modelEmotion regulationDepressive symptomsReciprocal associationsSleep problemsDevelopment of depressive symptomsDepressive symptoms 6 monthsFour-wave longitudinal studyGender differencesPanel modelTargeted sleep interventionsSymptoms 6 monthsSleep interventionsMultigroup analysisEmotionsLongitudinal studyAdolescentsSleepSymptomsIntervention strategiesGirlsMultigroupBoysAssociationMusic mindfulness acutely modulates autonomic activity and improves psychological state in anxiety and depression
Ramirez C, Alayine G, Akafia C, Adichie K, Watts D, Galdamez Y, Harding L, Allsop A. Music mindfulness acutely modulates autonomic activity and improves psychological state in anxiety and depression. Frontiers In Neuroscience 2025, 19: 1554156. PMID: 40264912, PMCID: PMC12013341, DOI: 10.3389/fnins.2025.1554156.Peer-Reviewed Original ResearchMusical mindSymptoms of anxietyMindfulness sessionsMusic listeningMusicImproved psychological stateHeart rate variabilityModerate symptoms of anxietyPsychological stateStates of consciousnessParticipants’ psychological statesMindfulnessSelf-reported sexDepressive symptomsLive sessionsStress managementMeasures of heart rate variabilitySocial connectionsIncreased HRVReduce stressEEG power spectral densityPsychological effectsAnxietyDepressionParticipantsModifiable risk factors for stroke, dementia and late-life depression: a systematic review and DALY-weighted risk factors for a composite outcome
Senff J, Tack R, Mallick A, Gutierrez-Martinez L, Duskin J, Kimball T, Tan B, Chemali Z, Newhouse A, Kourkoulis C, Rivier C, Falcone G, Sheth K, Lazar R, Ibrahim S, Pikula A, Tanzi R, Fricchione G, Brouwers H, Rinkel G, Yechoor N, Rosand J, Anderson C, Singh S. Modifiable risk factors for stroke, dementia and late-life depression: a systematic review and DALY-weighted risk factors for a composite outcome. Journal Of Neurology Neurosurgery & Psychiatry 2025, 96: 515-527. PMID: 40180437, DOI: 10.1136/jnnp-2024-334925.Peer-Reviewed Original ResearchConceptsModifiable risk factorsLate-life depressionDisability-adjusted life yearsMeta-analysesRisk factorsComposite outcomeRelevant meta-analysesBody mass indexPhysical activityIdentified risk factorsComposite outcome of strokeHearing lossIncidence of strokeDepressive symptomsPrevention strategiesLife yearsOutcome of strokeSystematic reviewInclusion criteriaMass indexDementiaFasting plasma glucoseEffect sizeSystematic literature reviewSocial engagementComplementary and integrative health approaches used for pain management by U.S. adults with chronic fatigue syndrome/myalgic encephalomyelitis: Findings from the 2022 National Health Interview Survey
Adamowicz J, Sirotiak Z, Thomas E, Lund B, Hadlandsmyth K, Driscoll M. Complementary and integrative health approaches used for pain management by U.S. adults with chronic fatigue syndrome/myalgic encephalomyelitis: Findings from the 2022 National Health Interview Survey. European Journal Of Integrative Medicine 2025, 75: 102443. DOI: 10.1016/j.eujim.2025.102443.Peer-Reviewed Original ResearchIntegrative health approachesHealth approachChronic fatigue syndrome/myalgic encephalomyelitisPain-relatedDepressive symptomsNational Health Interview Survey dataU.S. National Health Interview Survey dataPain managementHealth Interview Survey dataNational Health Interview SurveyIntegrative health modalityRao-Scott chi-square testsHealth Interview SurveyInterview Survey dataChiropractic careHealth modalitiesInterview SurveySurvey weightsChi-square testU.S. adultsRao-ScottExperience painAssociated with usageHealth useCFS/MEAssociation between loneliness and suicidality among general populations and persons with depressive and bipolar disorders: A systematic review
Lu A, Chan A, Menon T, Le G, Wong S, Ho R, Lo H, Rhee T, Lim P, Guillen-Burgos H, McIntyre R. Association between loneliness and suicidality among general populations and persons with depressive and bipolar disorders: A systematic review. Journal Of Affective Disorders 2025, 380: 777-801. PMID: 40157511, DOI: 10.1016/j.jad.2025.03.150.Peer-Reviewed Original ResearchConceptsGeneral population sampleBipolar disorderSystematic reviewPopulation sampleAge groupsHealthy adultsWeb of ScienceOlder adultsUnadjusted modelsDepressive symptomsData extractionDepressive disorderEligibility criteriaModerate positive correlationNIH toolPositive associationLonelinessEvaluate personalitySuicideAdultsClinical diagnosisDisordersQuality assessmentAssociationComprehensive assessment
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply