2025
Kleptomania on the impulsive–compulsive spectrum. Clinical and therapeutic considerations for women
Munguía L, Baenas-Soto I, Granero R, Fábregas-Balcells M, Gaspar-Pérez A, Rosinska M, Potenza M, Cuquerella Á, Tapia-Martínez J, Cabús-Grange R, Taranilla-Castro A, Macharé-Alberni M, Talón-Navarro M, Fernández-Aranda F, Jiménez-Murcia S. Kleptomania on the impulsive–compulsive spectrum. Clinical and therapeutic considerations for women. Scientific Reports 2025, 15: 7886. PMID: 40050325, PMCID: PMC11885670, DOI: 10.1038/s41598-025-85705-9.Peer-Reviewed Original ResearchConceptsImpulsive-compulsive spectrumDSM-5 criteriaClinical groupsDSM-5Personality featuresSemi-structured clinical interviewTreatment outcomesHarm avoidance scoresCognitive behavioral treatmentHealthy control individualsSample of female patientsImpact treatment outcomesPoor treatment outcomesCompulsive featuresBehavioral treatmentHigher impulsivityAvoidance scoresClinical interviewKleptomaniaInvestigate treatment outcomesCharacteristics of peopleFemale participantsPsychopathologyClinical samplesTreatment approachesMentalisation-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales (Mentalization for Offending Adult Males, MOAM): a multicentre, assessor-blinded, randomised controlled trial
Fonagy P, Simes E, Yirmiya K, Wason J, Barrett B, Frater A, Cameron A, Butler S, Hoare Z, McMurran M, Moran P, Crawford M, Pilling S, Allison E, Yakeley J, Bateman A. Mentalisation-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales (Mentalization for Offending Adult Males, MOAM): a multicentre, assessor-blinded, randomised controlled trial. The Lancet Psychiatry 2025, 12: 208-219. PMID: 39978982, DOI: 10.1016/s2215-0366(24)00445-0.Peer-Reviewed Original ResearchConceptsOvert Aggression Scale-ModifiedAntisocial personality disorderMentalisation-based treatmentPersonality disorderDSM-5 criteriaReducing aggressive behaviorService supervisionGroup therapy sessionsEffects of thoughtsCriminal justice systemForensic populationsTreatment gainsDSM-5Psychological treatmentPathway servicesTherapy sessionsAggressive behaviorIndividual sessionsJustice systemCommunity probationFollow-up timepointsUsual groupProbationFindings’ generalisability,Trial proceduresLUMATEPERONE IN THE TREATMENT OF PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND BIPOLAR DISORDER WITH ANXIOUS DISTRESS AND MIXED FEATURES
Bhagwagar *, Kozauer S, Earley W, Huo J, Sachs G, Durgam S. LUMATEPERONE IN THE TREATMENT OF PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND BIPOLAR DISORDER WITH ANXIOUS DISTRESS AND MIXED FEATURES. The International Journal Of Neuropsychopharmacology 2025, 28: i316-i316. PMCID: PMC11814723, DOI: 10.1093/ijnp/pyae059.563.Peer-Reviewed Original ResearchClinical Global Impression Scale-SeverityMajor depressive disorderMADRS total scoreClinical Global Impression Scale-Severity scoresAnxious distressBipolar depressionBipolar II disorderDSM-5Bipolar disorderTotal scoreII disorderBipolar IDepressive disorderDepressive episodeAssociated with major depressive disorderDepression Rating ScaleDSM-5 criteriaBipolar disorder diagnosisPost-hoc analysis of studyIncreased suicide riskPoor treatment responseSingle-item scoresEpisode specifierTreat schizophreniaDisorder diagnosis
2024
Delays in bipolar depression treatment in primary care vs. integrated behavioral health and specialty care
Park J, Breitinger S, Savitz S, Gardea-Resendez M, Singh B, Williams M, Frye M. Delays in bipolar depression treatment in primary care vs. integrated behavioral health and specialty care. Journal Of Affective Disorders 2024, 369: 404-410. PMID: 39389118, DOI: 10.1016/j.jad.2024.10.011.Peer-Reviewed Original ResearchIntegrated behavioral healthBipolar depression treatmentBipolar depressionBipolar disorderCollaborative care modelPrimary careCare modelSpecialty clinicsDepression treatmentEpisodes of bipolar depressionBehavioral healthDSM-5 criteriaSwitching to monotherapyPharmacological treatment patternsRetrospective study of adultsDepressive episodeDSM-5Mood stabilizersCompare treatment recommendationsStudy of adultsAntidepressant useGroup differencesDepression careEvidence of delayRetrospective study designDifferences in Mental Illness Stigma by Disorder and Gender: Population-Based Vignette Randomized Experiment in Rural Uganda.
Lee Y, Christ R, Mbabazi R, Dabagia J, Prendergast A, Wykoff J, Dasari S, Safai D, Nakaweesi S, Aturinde S, Galvin M, Akena D, Ashaba S, Waiswa P, Rosenheck R, Tsai A. Differences in Mental Illness Stigma by Disorder and Gender: Population-Based Vignette Randomized Experiment in Rural Uganda. PLOS Mental Health 2024, 1: e0000069. PMID: 39188639, PMCID: PMC11345708, DOI: 10.1371/journal.pmen.0000069.Peer-Reviewed Original ResearchMental illness stigmaIllness stigmaAnxiety disordersMental disordersLevels of mental illness stigmaRural UgandaImprove population mental healthAnti-stigma initiativesLevel of stigmaPopulation mental healthGeneralized anxiety disorderDSM-5 criteriaAlcohol use disorderEmpirical p-valuesVignette studyMental illnessPairwise mean comparisonsDistricts of UgandaPopulation-basedMental healthDepressive disorderGender combinationsUse disorderSecondary analysisStudy participantsEmotional State Transitions in Trauma-Exposed Individuals With and Without Posttraumatic Stress Disorder
Korem N, Duek O, Spiller T, Ben-Zion Z, Levy I, Harpaz-Rotem I. Emotional State Transitions in Trauma-Exposed Individuals With and Without Posttraumatic Stress Disorder. JAMA Network Open 2024, 7: e246813. PMID: 38625701, PMCID: PMC11022112, DOI: 10.1001/jamanetworkopen.2024.6813.Peer-Reviewed Original ResearchPosttraumatic stress disorderTrauma-exposed individualsEmotional numbing symptomsTrauma-exposed controlsNegative emotional statesNumbing symptomsEmotional numbingDSM-5Valence ratingsStress disorderEmotional statesTrauma-exposed control groupPTSD experiencesPosttraumatic stress disorder symptomsPosttraumatic Stress Disorder ChecklistDSM-5 criteriaAge-related associationsStimulus valencePCL-5Emotional responsesEmotional state transitionEmotional transitionSymptomsParticipantsDisorders
2023
Methamphetamine-Associated Catatonia: Case Series and Systematic Review of the Literature from 1943-2020
Slavnic B, Barnett B, McIntire S, Becker R, Saba S, Vellanki K, Honaker L, Weleff J, Carroll B. Methamphetamine-Associated Catatonia: Case Series and Systematic Review of the Literature from 1943-2020. Annals Of Clinical Psychiatry 2023, 35: 167-177. PMID: 37459499, DOI: 10.12788/acp.0116.Peer-Reviewed Original ResearchConceptsAssociated with catatoniaCatatonia Rating ScaleMethamphetamine useGeneral medical conditionsCase seriesBush-Francis Catatonia Rating ScaleSystematic reviewUrine drug screensMedical conditionsRating ScaleCases of catatoniaDSM-5 criteriaShorter hospitalDopamine functionCatatonic patientsCatatoniaDSM-5MethamphetaminePatientsNeural mechanismsSubstance intoxicationDrug screeningHospitalReviewLorazepamDSM-5 Criterion-A-Based Trauma Types in Service Members and Veterans Seeking Treatment for Posttraumatic Stress Disorder
Benfer N, Grunthal B, Dondanville K, Young-McCaughan S, Blankenship A, Abdallah C, Back S, Flanagan J, Foa E, Fox P, Krystal J, Marx B, McGeary D, McLean C, Pruiksma K, Resick P, Roache J, Shiroma P, Sloan D, Taylor D, Wachen J, López-Roca A, Nicholson K, Schobitz R, Schrader C, Sharrieff A, Yarvis J, Mintz J, Keane T, Peterson A, Litz B. DSM-5 Criterion-A-Based Trauma Types in Service Members and Veterans Seeking Treatment for Posttraumatic Stress Disorder. Psychological Trauma Theory Research Practice And Policy 2023, 16: 1218-1228. PMID: 37410416, PMCID: PMC10770283, DOI: 10.1037/tra0001537.Peer-Reviewed Original ResearchPosttraumatic stress disorderTrauma typesBehavioral health problemsHealth problemsStress disorderMoral injuryParticipants' ratingsLife threatAftermath of violenceMental health problemsDSM-5 criteriaTraumatic eventsParticipants' endorsementClinical trialsDifferent traumasTyping schemeTraumatic lossAssessor judgementsService membersTraumaClinical researchersParticipantsUnique contextInjuryMilitary personnelExamining the relationship of concurrent obesity and tobacco use disorder on the development of substance use disorders and psychiatric conditions: Findings from the NESARC-III
Fields L, Roberts W, Schwing I, McCoy M, Verplaetse T, Peltier M, Carretta R, Zakiniaeiz Y, Rosenheck R, McKee S. Examining the relationship of concurrent obesity and tobacco use disorder on the development of substance use disorders and psychiatric conditions: Findings from the NESARC-III. Drug And Alcohol Dependence Reports 2023, 7: 100162. PMID: 37159814, PMCID: PMC10163607, DOI: 10.1016/j.dadr.2023.100162.Peer-Reviewed Original ResearchTobacco use disorderSubstance use disordersBody mass indexUse disordersPsychiatric conditionsRisk of SUDAdditional substance use disordersSingle health conditionsRelated Conditions Wave IIIWorse health outcomesNational Epidemiological SurveyPsychiatric disorder diagnosisHarmful substance useDSM-5 criteriaConcurrent obesityComorbid obesityMass indexSUD diagnosisRisk factorsObesityComorbid diagnosesEpidemiological surveyHealth outcomesNESARC-IIIDisorder diagnosis
2022
Association of current and remitted bipolar disorders with health-related quality of life: Findings from a nationally representative sample in the US
Rhee TG, Gillissie ES, Nierenberg AA, McIntyre RS. Association of current and remitted bipolar disorders with health-related quality of life: Findings from a nationally representative sample in the US. Journal Of Affective Disorders 2022, 321: 33-40. PMID: 36273681, DOI: 10.1016/j.jad.2022.10.025.Peer-Reviewed Original ResearchConceptsQuality-adjusted life yearsCurrent bipolar disorderHealth-related qualityBipolar disorderNon-institutionalized adultsLower mental HRQoLNational Epidemiological SurveyRelated Conditions-IIIDSM-5 criteriaMental HRQOLRepresentative sampleHRQoLRemissionEpidemiological surveyLife yearsPast yearStudy sampleAdultsRegression analysisConditions-IIIDisordersAssociationRole of covariatesYearsGroup
2021
Does Confinement Affect Treatment Dropout Rates in Patients With Gambling Disorder? A Nine-Month Observational Study
Baenas I, Etxandi M, Codina E, Granero R, Fernández-Aranda F, Gómez-Peña M, Moragas L, Rivas S, Potenza M, Håkansson A, del Pino-Gutiérrez A, Mora-Maltas B, Valenciano-Mendoza E, Menchón J, Jiménez-Murcia S. Does Confinement Affect Treatment Dropout Rates in Patients With Gambling Disorder? A Nine-Month Observational Study. Frontiers In Psychology 2021, 12: 761802. PMID: 34970193, PMCID: PMC8712884, DOI: 10.3389/fpsyg.2021.761802.Peer-Reviewed Original ResearchTreatment dropout ratesTreatment durationPredictors of dropoutTreatment dropoutHigh-risk individualsShorter treatment durationGambling disorderCOVID-19 pandemicObservational periodDSM-5 criteriaBrief telephone surveyClinical featuresMean ageDropout rateTreatment outcomesClinical dataObservational studyDepressive symptomsPatientsTreatment approachesCOVID-19 concernsBriefer durationAddiction unitRisk of dropoutTelephone surveySudden Unexpected Death as a Traumatic Stressor: The Impact of the DSM–5 Revision of Criterion A for Posttraumatic Stress Disorder
Domino J, Whiteman S, Davis M, Witte T, Weathers F. Sudden Unexpected Death as a Traumatic Stressor: The Impact of the DSM–5 Revision of Criterion A for Posttraumatic Stress Disorder. Traumatology An International Journal 2021, 27: 168-176. DOI: 10.1037/trm0000272.Peer-Reviewed Original ResearchDSM-5 definitionPosttraumatic stress disorderUnexpected deathCriterion AStress disorderPTSD symptomsIndirect exposureSevere motor vehicle accidentSudden unexpected deathMotor vehicle accidentsDSM-IV criteriaIndividual PTSD symptomsDSM-5 criteriaDSM-IV definitionOrdinal logistic regressionTrauma groupPTSD symptom clustersDSM-5 criterion ASymptom profilesVehicle accidentsMental disordersSymptom clustersDSM-IVLogistic regressionTrauma-exposed college studentsCurrent and Future Prevalence Estimates of Mild Cognitive Impairment, Dementia, and Its Subtypes in a Population-Based Sample of People 70 Years and Older in Norway: The HUNT Study
GjØra L, Strand B, Bergh S, Borza T, Brækhus A, Engedal K, Johannessen A, Kvello-Alme M, Krokstad S, Livingston G, Matthews F, Myrstad C, Skjellegrind H, Thingstad P, Aakhus E, Aam S, Selbæk G. Current and Future Prevalence Estimates of Mild Cognitive Impairment, Dementia, and Its Subtypes in a Population-Based Sample of People 70 Years and Older in Norway: The HUNT Study. Journal Of Alzheimer’s Disease 2021, 79: 1213-1226. PMID: 33427745, PMCID: PMC7990439, DOI: 10.3233/jad-201275.Peer-Reviewed Original ResearchConceptsPrevalence of dementiaMild cognitive impairmentEpidemiology of mild cognitive impairmentPopulation-based sample of peoplePrevalence of mild cognitive impairmentPopulation-based samplePopulation-based studyCognitive impairmentSample of peopleHUNT StudyNursing homesStandardized prevalenceDementia subtypesHealth StudyCarer questionnairesHealthcare systemYears of ageCalculated prevalenceDementiaPopulation representativeClinical expertsHUNT4Cognitive testsDSM-5 criteriaPrevalence
2020
A feasibility study providing substance use treatment in the Black church
Jordan A, Babuscio T, Nich C, Carroll KM. A feasibility study providing substance use treatment in the Black church. Journal Of Substance Use And Addiction Treatment 2020, 124: 108218. PMID: 33771290, DOI: 10.1016/j.jsat.2020.108218.Peer-Reviewed Original ResearchConceptsTechnology-based treatmentsClinical trialsSUD treatmentBlack adultsNonrandomized feasibility studyUrine toxicology screenHealth care disparitiesEvidence-based interventionsDSM-5 criteriaAdequate numberCognitive behavioral therapyDisseminable strategyUndertreated populationToxicology screenCurrent SUDCare disparitiesHealth advisorsBehavioral therapySubstance useMean numberTreatmentHigh uptakeFeasibility studyCBT4CBTTrialsLongitudinal imaging of metabotropic glutamate 5 receptors during early and extended alcohol abstinence
Hillmer AT, Angarita GA, Esterlis I, Anderson JM, Nabulsi N, Lim K, Ropchan J, Carson RE, Krystal JH, Malley S, Cosgrove KP. Longitudinal imaging of metabotropic glutamate 5 receptors during early and extended alcohol abstinence. Neuropsychopharmacology 2020, 46: 380-385. PMID: 32919411, PMCID: PMC7852514, DOI: 10.1038/s41386-020-00856-9.Peer-Reviewed Original ResearchConceptsMetabotropic glutamate 5 receptorsSmoking statusAlcohol abstinenceEarly abstinenceMGlu5 receptor negative allosteric modulatorReceptor negative allosteric modulatorChronic alcohol useCortical brain regionsAlcohol use disorderEmission Tomography ImagingPositron emission tomography (PET) imagingNegative allosteric modulatorsDSM-5 criteriaCue-induced reinstatementHealthy controlsPreclinical literatureGlutamate systemPreclinical modelsHuman evidenceReceptor drugsPET scansUse disordersHuman studiesReceptor availabilityStudy durationThe impact of delirium on withdrawal of life-sustaining treatment after intracerebral hemorrhage.
Reznik ME, Moody S, Murray K, Costa S, Grory BM, Madsen TE, Mahta A, Wendell LC, Thompson BB, Rao SS, Stretz C, Sheth KN, Hwang DY, Zahuranec DB, Schrag M, Daiello LA, Asaad WF, Jones RN, Furie KL. The impact of delirium on withdrawal of life-sustaining treatment after intracerebral hemorrhage. Neurology 2020, 95: e2727-e2735. PMID: 32913011, PMCID: PMC7734724, DOI: 10.1212/wnl.0000000000010738.Peer-Reviewed Original ResearchConceptsImpact of deliriumIntracerebral hemorrhageLife-sustaining treatmentScore-based modelSingle-center cohort studyCox regression modelCharacteristic curve analysisDSM-5 criteriaHospital daysCohort studyConsecutive patientsMedian timeDelirium groupPoor outcomeDeliriumWLSTPatientsLogistic regressionCurve analysisHemorrhageThiol/Disulfide Homeostasis in Bipolar and Unipolar Depression
Erzin G, Özkaya G, Topçuoğlu C, Yüksel R, Erel Ö, Yurt E, Göka E, Gülöksüz S. Thiol/Disulfide Homeostasis in Bipolar and Unipolar Depression. Clinical Psychopharmacology And Neuroscience 2020, 18: 395-401. PMID: 32702218, PMCID: PMC7383011, DOI: 10.9758/cpn.2020.18.3.395.Peer-Reviewed Original ResearchDisulfide/total thiol ratiosTotal thiol ratiosThiol-disulfide homeostasisBipolar depressionHealthy controlsUnipolar depressionNative thiol ratioBipolar disorderDisulfide levelsThiol ratioDepressive disorderNative thiolAnkara Numune TrainingThiol/disulfide homeostasisDisulfide/native thiol ratioOxidative stress markersUnipolar depressive disorderDSM-5 criteriaLevels of disulfideUD groupOutpatient clinicClinical entityDepressive episodeResearch HospitalTherapeutic differencesMajor depressive disorder and impaired health‐related quality of life among US older adults
Rhee TG, Steffens DC. Major depressive disorder and impaired health‐related quality of life among US older adults. International Journal Of Geriatric Psychiatry 2020, 35: 1189-1197. PMID: 32497391, DOI: 10.1002/gps.5356.Peer-Reviewed Original ResearchConceptsPast major depressive disorderCurrent major depressive disorderMajor depressive disorderMental component summaryHealth-related qualityPhysical component summaryQuality-adjusted life yearsHRQOL measuresOlder adultsComponent summaryDepressive disorderMultivariable-adjusted linear regressionCurrent MDD groupLifetime major depressive disorderRelated Conditions Wave IIIHealth Interview SurveyHistory of MDDUS older adultsNational Epidemiological SurveyCross-sectional analysisDSM-5 criteriaLower HRQoLResidual impairmentWave IIIEpidemiological surveyAutism Spectrum Disorder and Schizophrenia Are Better Differentiated by Positive Symptoms Than Negative Symptoms
Trevisan DA, Foss-Feig JH, Naples AJ, Srihari V, Anticevic A, McPartland JC. Autism Spectrum Disorder and Schizophrenia Are Better Differentiated by Positive Symptoms Than Negative Symptoms. Frontiers In Psychiatry 2020, 11: 548. PMID: 32595540, PMCID: PMC7301837, DOI: 10.3389/fpsyt.2020.00548.Peer-Reviewed Original ResearchAutism spectrum disorderSpectrum disorderNegative symptomsAutism Diagnostic Observation SchedulePositive symptomsGold standard diagnostic assessmentHeterogenous neurodevelopmental disorderAnalysis of covarianceDSM-5 criteriaStereotyped languageTD adultsASD symptomsTypical developmentObservation ScheduleRepetitive behaviorsCommunicative behaviorNegative Syndrome ScaleStandardized measuresSZ groupSymptom domainsGroup differencesParticipant groupsSymptom overlapSZ symptomsNeurodevelopmental disordersDo Sex Differences Among Adults With Opioid Use Disorder Reflect Sex-specific Vulnerabilities? A Study of Behavioral Health Comorbidities, Pain, and Quality of Life.
Rhee TG, Peltier MR, Sofuoglu M, Rosenheck RA. Do Sex Differences Among Adults With Opioid Use Disorder Reflect Sex-specific Vulnerabilities? A Study of Behavioral Health Comorbidities, Pain, and Quality of Life. Journal Of Addiction Medicine 2020, 14: 502-509. PMID: 32371659, PMCID: PMC8962823, DOI: 10.1097/adm.0000000000000662.Peer-Reviewed Original ResearchConceptsPast-year opioid use disorderOpioid use disorderSubstance use disordersUse disordersTreatment of OUDPast-year substance use disorderBehavioral health comorbiditiesPast-year psychiatric disordersSex differencesHealth-related qualityRelated Conditions Wave IIIBehavioral health conditionsNon-institutionalized adultsLogistic regression analysisQuality of lifeNational Epidemiological SurveyDSM-5 criteriaSocio-demographic factorsHealth comorbiditiesConcurrent disordersUS adultsPsychiatric disordersDiagnostic criteriaOUD statusWave III
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