2025
Randomized Controlled Trial of Weight Management Versus Weight Management With Concurrent Cognitive‐Behavioral Therapy for Binge‐Eating Disorder in US Veterans With High Weight
Masheb R, Buta E, Snow J, Munro L, Lawless M, Abel E, McWain N, Marsh A, Cary A, Grilo C, Raffa S, Ruser C. Randomized Controlled Trial of Weight Management Versus Weight Management With Concurrent Cognitive‐Behavioral Therapy for Binge‐Eating Disorder in US Veterans With High Weight. International Journal Of Eating Disorders 2025 PMID: 40485646, DOI: 10.1002/eat.24476.Peer-Reviewed Original ResearchDSM-5 binge-eating disorderBinge-eating disorderDSM-5Cognitive-behavioral therapyEating-disorder treatmentRemission rateUS military veteransBinge-eating frequencyMilitary veteransCBTVeteran populationShape-relatedVeteransWeight managementPost-treatmentWeight management programUS veteransMixed-effects modelsDisordersRandomized controlled trialsClinical Trials Registry numberPsychopathologyBinge-eatingWeight lossClinical guidanceInterpersonal difficulties and suicidal ideation in young people at clinical high-risk for psychosis and help-seeking clinical controls
Bailey A, Bauer B, Mittal V, Ellman L, Strauss G, Walker E, Powers A, Kenney J, Corlett P, Woods S, Gold J, Schiffman J, Waltz J, Silverstein S. Interpersonal difficulties and suicidal ideation in young people at clinical high-risk for psychosis and help-seeking clinical controls. Psychiatry Research 2025, 348: 116467. PMID: 40184931, PMCID: PMC12051163, DOI: 10.1016/j.psychres.2025.116467.Peer-Reviewed Original ResearchConceptsRates of suicidal ideationPresence of suicidal ideationClinical high riskSuicidal ideationInterpersonal difficultiesMental health concernsInterpersonal traumaExperiences of suicidal ideationHelp-seeking controlsDSM-5 diagnosisSame-age peersDSM-5Interpersonal mechanismsDiagnostic groupsIdeationYoung peoplePsychosisClinical controlCHRPHealth concernHigh riskAssociated with presenceDifficultiesSuicideLogistic regression modelsDiagnostic accuracy and psychometric performance of two self‐report measures of posttraumatic stress disorder in older veterans
Cook J, Pietrzak R, Kimerling R, Schnurr P, Bovin M. Diagnostic accuracy and psychometric performance of two self‐report measures of posttraumatic stress disorder in older veterans. Journal Of Traumatic Stress 2025 PMID: 40097911, DOI: 10.1002/jts.23154.Peer-Reviewed Original ResearchPosttraumatic stress disorderPC-PTSD-5DSM-5PCL-5Stress disorderSelf-report measures of posttraumatic stress disorderMeasures of posttraumatic stress disorderOlder veteransPsychometric propertiesPosttraumatic Stress Disorder ChecklistPosttraumatic stress disorder prevalencePrimary Care PTSD ScreenSelf-report measuresSample of veteransOptimal cutoff scoreU.S. Department of Veterans AffairsPTSD screenCutoff scoreDepartment of Veterans AffairsYounger veteransPsychometric performanceTested PSVeteransOlder adultsPrimary care servicesPhysical health correlates of co-occurring chronic pain and PTSD Among U.S. Veterans: Results from a nationally representative study
Reed D, Fischer I, Williams R, Na P, Engel C, Pietrzak R. Physical health correlates of co-occurring chronic pain and PTSD Among U.S. Veterans: Results from a nationally representative study. Psychiatry Research 2025, 348: 116440. PMID: 40088518, DOI: 10.1016/j.psychres.2025.116440.Peer-Reviewed Original ResearchConceptsPhysical health conditionsCo-occurring chronic painPosttraumatic stress disorderHealth conditionsChronic painU.S. veteransNational Health and ResilienceNon-Hispanic whitesMental health concernsPhysical health correlatesPosttraumatic Stress Disorder ChecklistPosttraumatic stress disorder diagnosisU.S. veteran populationNationally representative samplePhysical functionLogistic regression analysisPsychosocial burdenVeterans StudyVeteran populationSelf-reportDSM-5Representative sampleStress disorderVeteransHealth concernKleptomania on the impulsive–compulsive spectrum. Clinical and therapeutic considerations for women
Munguía L, Baenas-Soto I, Granero R, Fábregas-Balcells M, Gaspar-Pérez A, Rosinska M, Potenza M, Cuquerella Á, Tapia-Martínez J, Cabús-Grange R, Taranilla-Castro A, Macharé-Alberni M, Talón-Navarro M, Fernández-Aranda F, Jiménez-Murcia S. Kleptomania on the impulsive–compulsive spectrum. Clinical and therapeutic considerations for women. Scientific Reports 2025, 15: 7886. PMID: 40050325, PMCID: PMC11885670, DOI: 10.1038/s41598-025-85705-9.Peer-Reviewed Original ResearchConceptsImpulsive-compulsive spectrumDSM-5 criteriaClinical groupsDSM-5Personality featuresSemi-structured clinical interviewTreatment outcomesHarm avoidance scoresCognitive behavioral treatmentHealthy control individualsSample of female patientsImpact treatment outcomesPoor treatment outcomesCompulsive featuresBehavioral treatmentHigher impulsivityAvoidance scoresClinical interviewKleptomaniaInvestigate treatment outcomesCharacteristics of peopleFemale participantsPsychopathologyClinical samplesTreatment approachesConnectome-Based Predictive Modeling of PTSD Development Among Recent Trauma Survivors
Ben-Zion Z, Simon A, Rosenblatt M, Korem N, Duek O, Liberzon I, Shalev A, Hendler T, Levy I, Harpaz-Rotem I, Scheinost D. Connectome-Based Predictive Modeling of PTSD Development Among Recent Trauma Survivors. JAMA Network Open 2025, 8: e250331. PMID: 40063028, PMCID: PMC11894499, DOI: 10.1001/jamanetworkopen.2025.0331.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingPosttraumatic stress disorderClinician-Administered PTSD Scale for DSM-5Months post-traumaFunctional magnetic resonance imagingTrauma survivorsDSM-5Post-traumaPosttraumatic stress disorder symptom clustersPosttraumatic stress disorder symptom severityPosttraumatic stress disorder symptom trajectoriesPosttraumatic stress disorder severityTask-based fMRI dataAnterior default modePredictive of symptomsFollow-up assessmentDevelopment of effective personalized treatmentsComprehensive clinical assessmentClinician-AdministeredNeurobiological indicesPosttraumatic psychopathologyHyperarousal symptomsCentral executiveTrauma exposureSalience networkA multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis
Peng P, Hao Y, Zhang X, Ma Y, Liu X, Shen D, Shen W, Zhao B, Li D, Beck S, Nunez Y, Potenza M, Gelernter J, Liu T, Yang B. A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis. Annals Of General Psychiatry 2025, 24: 12. PMID: 40033412, PMCID: PMC11877697, DOI: 10.1186/s12991-025-00546-0.Peer-Reviewed Original ResearchSemi-Structured Assessment for Drug Dependence and AlcoholismDSM-5 diagnostic criteriaGambling disorderDSM-5Antisocial personality disorderMethamphetamine use disorderSubstance use disordersDiagnostic criteriaPersonality disorderBridge symptomsDepressive episodeDrug rehabilitation centersCentral symptomsPsychiatric diagnosisGambling durationUse disorderSelf-harmChildhood experiencesMethamphetamineAlcohol useViolent experiencesDisordersManifest symptomsChinese versionMDEMentalisation-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales (Mentalization for Offending Adult Males, MOAM): a multicentre, assessor-blinded, randomised controlled trial
Fonagy P, Simes E, Yirmiya K, Wason J, Barrett B, Frater A, Cameron A, Butler S, Hoare Z, McMurran M, Moran P, Crawford M, Pilling S, Allison E, Yakeley J, Bateman A. Mentalisation-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales (Mentalization for Offending Adult Males, MOAM): a multicentre, assessor-blinded, randomised controlled trial. The Lancet Psychiatry 2025, 12: 208-219. PMID: 39978982, DOI: 10.1016/s2215-0366(24)00445-0.Peer-Reviewed Original ResearchConceptsOvert Aggression Scale-ModifiedAntisocial personality disorderMentalisation-based treatmentPersonality disorderDSM-5 criteriaReducing aggressive behaviorService supervisionGroup therapy sessionsEffects of thoughtsCriminal justice systemForensic populationsTreatment gainsDSM-5Psychological treatmentPathway servicesTherapy sessionsAggressive behaviorIndividual sessionsJustice systemCommunity probationFollow-up timepointsUsual groupProbationFindings’ generalisability,Trial proceduresLUMATEPERONE IN THE TREATMENT OF PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND BIPOLAR DISORDER WITH ANXIOUS DISTRESS AND MIXED FEATURES
Bhagwagar *, Kozauer S, Earley W, Huo J, Sachs G, Durgam S. LUMATEPERONE IN THE TREATMENT OF PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND BIPOLAR DISORDER WITH ANXIOUS DISTRESS AND MIXED FEATURES. The International Journal Of Neuropsychopharmacology 2025, 28: i316-i316. PMCID: PMC11814723, DOI: 10.1093/ijnp/pyae059.563.Peer-Reviewed Original ResearchClinical Global Impression Scale-SeverityMajor depressive disorderMADRS total scoreClinical Global Impression Scale-Severity scoresAnxious distressBipolar depressionBipolar II disorderDSM-5Bipolar disorderTotal scoreII disorderBipolar IDepressive disorderDepressive episodeAssociated with major depressive disorderDepression Rating ScaleDSM-5 criteriaBipolar disorder diagnosisPost-hoc analysis of studyIncreased suicide riskPoor treatment responseSingle-item scoresEpisode specifierTreat schizophreniaDisorder diagnosisLUMATEPERONE TREATMENT FOR MAJOR DEPRESSIVE EPISODES WITH MIXED FEATURES IN MAJOR DEPRESSIVE DISORDER AND BIPOLAR I OR BIPOLAR II DISORDER
Bhagwagar *, Kozauer S, Earley W, Chen C, Huo J, Stahl S, McIntyre R, Durgam S. LUMATEPERONE TREATMENT FOR MAJOR DEPRESSIVE EPISODES WITH MIXED FEATURES IN MAJOR DEPRESSIVE DISORDER AND BIPOLAR I OR BIPOLAR II DISORDER. The International Journal Of Neuropsychopharmacology 2025, 28: i19-i19. PMCID: PMC11815047, DOI: 10.1093/ijnp/pyae059.033.Peer-Reviewed Original ResearchBipolar depressionBipolar II disorderII disorderLumateperone treatmentMDD populationBipolar IDSM-5Baseline to dayDSM-5-TRIncreased suicide riskMixing featuresPoor treatment responseAdverse eventsMADRS totalTreatment-emergent adverse eventsCGI-S scoresHypomanic symptomsDepressive disorderExtrapyramidal symptomsTreat schizophreniaDepressive episodeConsistent with prior studiesLumateperoneSuicide riskMDDOral microbiota among treatment-naïve adolescents with depression: A case-control study
Zeng Y, Jia X, Li H, Zhou N, Liang X, Liu K, Yang B, Xiang B. Oral microbiota among treatment-naïve adolescents with depression: A case-control study. Journal Of Affective Disorders 2025, 375: 93-102. PMID: 39855566, PMCID: PMC11934967, DOI: 10.1016/j.jad.2025.01.089.Peer-Reviewed Original ResearchMajor depressive disorderArea under the curveCognitive functionOral microbiotaCase-control studyReceiver operating characteristicAdolescent depressionDSM-5 major depressive disorderAssociated with major depressive disorderTreatment naive individualsNon-depressed individualsMorning saliva samplesHealthy control groupGroup of adolescentsDepressive disorderDSM-5Visual breadthDelayed memoryDepression groupOral healthOral bacteriaHC individualsGut microbiota changesHC groupOral microbes
2024
Development and validation of the BRief Eating Disorder Screener (BREDS) for US veterans in healthcare and community settings
Masheb R, Batten A, Siegel S, Huggins J, Marsh A, Snow J, Munro L, Vogt D, White M, Maguen S. Development and validation of the BRief Eating Disorder Screener (BREDS) for US veterans in healthcare and community settings. General Hospital Psychiatry 2024, 93: 1-8. PMID: 39754995, DOI: 10.1016/j.genhosppsych.2024.12.021.Peer-Reviewed Original ResearchConceptsEating disorder diagnosisDSM-5Disorder diagnosisDSM-5 eating disorder diagnosesPrediction of diagnosisDiagnostic InterviewVA healthcareCommunity settingsUS veteransScreenerNational surveyArea under the curveItemsVeteransHealthcareYour bodyBriefSurveyYour lifeScreeningDiagnosisValidityInterviewsMental Health Service Referral and Treatment Following Screening and Assessment in Juvenile Detention.
Tedeschi F, Horwitz S, Surko M, Weinberger E, Bart A, Baetz C, Guo F, Alexander A, Havens J. Mental Health Service Referral and Treatment Following Screening and Assessment in Juvenile Detention. The Journal Of The American Academy Of Psychiatry And The Law 2024, 52: 460-469. PMID: 39393913, DOI: 10.29158/jaapl.240082-24.Peer-Reviewed Original ResearchAttention-deficit/hyperactivity disorderDSM-5 diagnosisMental health screeningDSM-5Prevalence of attention-deficit/hyperactivity disorderRates of mental health disordersPosttraumatic stress disorderProblematic substance useMental health disordersMental health service referralJuvenile detention facilitiesStress disorderAttention-deficit/hyperactivityDetained youthSubstance useNeurodevelopmental disordersHealth disordersJuvenile detentionDetention facilitiesEvaluate youthHealth screeningDisordersEmotional concernsAvailability of servicesService referralsCurrent Advances in Behavioral Addictions: From Fundamental Research to Clinical Practice
Brand M, Antons S, Bőthe B, Demetrovics Z, Fineberg N, Jimenez-Murcia S, King D, Mestre-Bach G, Moretta T, Müller A, Wegmann E, Potenza M. Current Advances in Behavioral Addictions: From Fundamental Research to Clinical Practice. American Journal Of Psychiatry 2024, 182: 155-163. PMID: 39659159, DOI: 10.1176/appi.ajp.20240092.Peer-Reviewed Original ResearchBehavioral addictionsAddictive behaviorsGaming disorderDisorders due to addictive behaviorsCompulsive sexual behavior disorderCompulsive buying-shopping disorderAttention deficit hyperactivity disorderCognitive-behavioral therapyBuying-shopping disorderSexual behavior disorderEmpirical supportInternet gaming disorderDeficit hyperactivity disorderPoor treatment outcomesResearch to clinical practiceDSM-5Gambling disorderICD-11Psychiatric disordersHyperactivity disorderBehavior problemsBehavioral disordersAddictionDiagnostic instrumentsEfficacious treatmentEating Disorders, Co‐Morbid Disorders and Early Risk Factors Amongst Post‐9/11 Veteran Men and Women
Cooper Z, Smith B, Kehle‐Forbes S, Dorset J, Mitchell K. Eating Disorders, Co‐Morbid Disorders and Early Risk Factors Amongst Post‐9/11 Veteran Men and Women. Journal Of Clinical Psychology 2024, 81: 133-144. PMID: 39648640, PMCID: PMC11802485, DOI: 10.1002/jclp.23756.Peer-Reviewed Original ResearchCo-occurring psychiatric disordersRates of eating disordersPosttraumatic stress disorderPsychiatric disordersEating disordersMilitary risk factorsStress disorderLevels of posttraumatic stress disorderCo-morbid psychiatric disordersCo-morbid psychiatric diagnosesDSM-5 eating disorder diagnosesComorbid psychiatric disordersBinge eating disorderCo-morbid disordersEating disorder diagnosisDocumented risk factorsLongitudinal studyEvidence-based treatmentsNon-veteransRisk factorsEarly risk factorsDSM-5Case statusDisorder onsetPsychiatric diagnosisPsychometric properties, factor structure, and functional correlates of the PTSD checklist for DSM-5 in a U.S. national sample of older veterans
Cook J, Bovin M, Günak M, Lawrence K, Pietrzak R. Psychometric properties, factor structure, and functional correlates of the PTSD checklist for DSM-5 in a U.S. national sample of older veterans. International Psychogeriatrics 2024, 37: 100027. PMID: 40086904, DOI: 10.1016/j.inpsyc.2024.100027.Peer-Reviewed Original ResearchPosttraumatic stress disorderPosttraumatic Stress Disorder ChecklistDSM-5PCL-5Psychometric propertiesOlder veteransSymptoms of posttraumatic stress disorderSubthreshold posttraumatic stress disorderAdult trauma exposurePCL-5 scoresMeasure PTSD symptomsSample of older veteransExcellent internal consistencyRates of childhoodNationally representative web-based surveyU.S. national sampleAssociated with measuresDysphoric symptomsPTSD symptomsStress disorderTrauma exposureFactor structureCommunity-dwelling older veteransAssessment measuresInternal consistencyDelays in bipolar depression treatment in primary care vs. integrated behavioral health and specialty care
Park J, Breitinger S, Savitz S, Gardea-Resendez M, Singh B, Williams M, Frye M. Delays in bipolar depression treatment in primary care vs. integrated behavioral health and specialty care. Journal Of Affective Disorders 2024, 369: 404-410. PMID: 39389118, DOI: 10.1016/j.jad.2024.10.011.Peer-Reviewed Original ResearchIntegrated behavioral healthBipolar depression treatmentBipolar depressionBipolar disorderCollaborative care modelPrimary careCare modelSpecialty clinicsDepression treatmentEpisodes of bipolar depressionBehavioral healthDSM-5 criteriaSwitching to monotherapyPharmacological treatment patternsRetrospective study of adultsDepressive episodeDSM-5Mood stabilizersCompare treatment recommendationsStudy of adultsAntidepressant useGroup differencesDepression careEvidence of delayRetrospective study designMulti-modal risk factors differentiate suicide attempters from ideators in military veterans with major depressive disorder
Goldstein K, Pietrzak R, Challman K, Chu K, Beck K, Brenner L, Interian A, Myers C, Shafritz K, Szeszko P, Goodman M, Haznedar M, Hazlett E. Multi-modal risk factors differentiate suicide attempters from ideators in military veterans with major depressive disorder. Journal Of Affective Disorders 2024, 369: 588-598. PMID: 39341292, DOI: 10.1016/j.jad.2024.09.149.Peer-Reviewed Original ResearchSuicide attemptsDepressive disorderGo/No-GoMilitary veteransSeverity of suicidal behaviorFractional anisotropyDecreased attentional controlUnited States military veteransDiagnosis of MDDDSM-5 diagnosisMagnetic-resonance-imagingSuicide prevention effortsDifferentiate veteransDSM-5Attentional controlSuicide attempt/sSuicidal behaviorSuicidal ideationMDDNeurocognitive assessmentHealthy control groupNeuroimaging variablesPrevention effortsIdeationSuicideThe association of perceived social support, resilience, and posttraumatic stress symptoms among coronavirus disease patients in the United States
Li J, Wisnivesky J, Gonzalez A, Feder A, Pietrzak R, Chanumolu D, Hu L, Kale M. The association of perceived social support, resilience, and posttraumatic stress symptoms among coronavirus disease patients in the United States. Journal Of Affective Disorders 2024, 368: 390-397. PMID: 39293600, DOI: 10.1016/j.jad.2024.09.091.Peer-Reviewed Original ResearchCOVID-19-related posttraumatic stress disorderPosttraumatic stress disorderPre-existing mental disordersSocial supportMental disordersPosttraumatic Stress Disorder ChecklistPosttraumatic stress disorder symptomsRisk of posttraumatic stress disorderCD-RISCPosttraumatic stress symptomsAcute careAssociation of perceived social supportMedical Outcomes Study Social Support SurveyTargeting of preventive interventionsConnor-Davidson Resilience ScalePsychological consequences of COVID-19Low social supportSocial Support SurveyMeasures of resilienceDSM-5Associated with lower oddsStress disorderStress symptomsCross-sectional designPsychological resilienceDisorders due to Substance Use: General Approaches
Kosten T, Domingo C. Disorders due to Substance Use: General Approaches. 2024, 2527-2542. DOI: 10.1007/978-3-030-51366-5_92.Peer-Reviewed Original ResearchSubstance use disordersDSM-5ICD-11Depressive symptomsSubstance use disorder criteriaBorderline personality disorderSubstance-induced conditionsGoal of abstinenceDrug withdrawal symptomsPersonality disorderDepressive disorderAgonist maintenanceWithdrawal symptomsAcute detoxificationLifetime substanceSUD diagnosisAbused drugsDevelopmental differencesUrine toxicologySubstance useAlcohol usePsychosocial rehabilitationDisordersDrug useSymptoms
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