2025
Randomized Controlled Trial of Weight Management Versus Weight Management With Concurrent Cognitive‐Behavioral Therapy for Binge‐Eating Disorder in US Veterans With High Weight
Masheb R, Buta E, Snow J, Munro L, Lawless M, Abel E, McWain N, Marsh A, Cary A, Grilo C, Raffa S, Ruser C. Randomized Controlled Trial of Weight Management Versus Weight Management With Concurrent Cognitive‐Behavioral Therapy for Binge‐Eating Disorder in US Veterans With High Weight. International Journal Of Eating Disorders 2025 PMID: 40485646, DOI: 10.1002/eat.24476.Peer-Reviewed Original ResearchDSM-5 binge-eating disorderBinge-eating disorderDSM-5Cognitive-behavioral therapyEating-disorder treatmentRemission rateUS military veteransBinge-eating frequencyMilitary veteransCBTVeteran populationShape-relatedVeteransWeight managementPost-treatmentWeight management programUS veteransMixed-effects modelsDisordersRandomized controlled trialsClinical Trials Registry numberPsychopathologyBinge-eatingWeight lossClinical guidanceSmartphone Apps for Problematic Pornography Use: A Review of Content and Quality
Hart-Derrick V, Virani S, Zadeh O, Genovese N, Engel J, Ponce Martinez C, Potenza M, McCurdy L. Smartphone Apps for Problematic Pornography Use: A Review of Content and Quality. Current Addiction Reports 2025, 12: 54. DOI: 10.1007/s40429-025-00669-0.Peer-Reviewed Original ResearchMobile App Rating ScaleProblematic pornography usePornography useMHealth appsCognitive-behavioral therapyEfficacious psychosocial treatmentsCognitive-behavioral skillsNegative psychosocial consequencesPsychosocial treatmentsRelationship difficultiesPsychological distressRating ScaleEngagement subscalesReview of contentSexual expectationsPsychosocial consequencesAccess treatmentSummaryOur resultsGoal settingHigher scoresMHealthSmartphone appMindfulness/meditationApp StorePornographyCombining Cognitive‐Behaviour Therapy With Mindfulness Training in a Digital Intervention for Binge Eating Disorder: A Single‐Session Pilot Trial
Sala M, Roos C, Kober H, Bricker J, Stern C, Plutchik J, John M, Haeny A, Feldman J, Aslan M, Hay J, Forman E. Combining Cognitive‐Behaviour Therapy With Mindfulness Training in a Digital Intervention for Binge Eating Disorder: A Single‐Session Pilot Trial. European Eating Disorders Review 2025 PMID: 40350587, DOI: 10.1002/erv.3204.Peer-Reviewed Original ResearchBinge Eating ScaleBinge eating episodesCognitive behavioral therapyEating disorder symptomsBinge-eating disorderEDE-QDisorder symptomsMindfulness trainingEating episodesGlobal eating disorder symptomsBinge Eating Scale scoresEating Disorder Examination QuestionnaireReducing binge eatingCognitive-behavioral therapyBinge eating disorderSingle-session interventionEnglish-speaking adultsCognitive-behavioralBinge eatingBehavioral therapyEating ScaleExamination QuestionnaireEating disordersEpisodic questionsDigital interventionsPreferences for Lisdexamfetamine vs Cognitive-Behavioral Therapy for Binge-Eating Disorder: Correlates and Outcomes.
Yurkow S, Ivezaj V, Pittman B, Grilo C. Preferences for Lisdexamfetamine vs Cognitive-Behavioral Therapy for Binge-Eating Disorder: Correlates and Outcomes. The Journal Of Clinical Psychiatry 2025, 86 PMID: 40338285, DOI: 10.4088/jcp.24m15552.Peer-Reviewed Original ResearchConceptsBinge-eating disorderTreatment preferencesModerate treatment outcomePatient treatment preferencesCognitive-behavioral therapyEffects of treatment preferenceTest main effectsCognitive-behavioralNo significant interaction effectsInteraction effectsBehavioral therapySignificant interaction effectCBTModerate outcomeEfficacious treatmentMain effectLisdexamfetamineTreatment outcomesParticipants' preferencesEffective interventionsEffects of treatmentDisordersRandomized controlled trialsNo preferenceLDXSession Preparation, Behavioral Rehearsal and Homework Assignment: Do these Therapeutic Delivery Strategies Improve Trauma Treatment Outcomes for Youth in Community Outpatient Settings?
Lee P, Lang J, Randall K. Session Preparation, Behavioral Rehearsal and Homework Assignment: Do these Therapeutic Delivery Strategies Improve Trauma Treatment Outcomes for Youth in Community Outpatient Settings? Journal Of Child & Adolescent Trauma 2025, 1-13. DOI: 10.1007/s40653-025-00709-x.Peer-Reviewed Original ResearchTF-CBTBehavioral rehearsalTrauma-focused cognitive-behavioral therapySymptom improvementImplementing TF-CBTCognitive-behavioral therapyPosttraumatic stress symptomsPotential treatment moderatorsCommunity outpatient settingsTreatment dosageTreatment moderatorsCompleted treatmentStress symptomsChild characteristicsHomework assignmentsTherapistsTreatment completionTreatment outcomesChildren aged 3Statewide disseminationSessionsRehearsalAged 3Administrative dataChildrenGender Minority Stress Themes and Suicide Prevention for Adult Transgender Inpatients: A Content Analysis of Brief Cognitive-Behavioral Therapy
Stubbing J, Everhardt K, Rice T, Saunders L, Tolin D, Rudd M, Diefenbach G. Gender Minority Stress Themes and Suicide Prevention for Adult Transgender Inpatients: A Content Analysis of Brief Cognitive-Behavioral Therapy. Psychology Of Sexual Orientation And Gender Diversity 2025 DOI: 10.1037/sgd0000830.Peer-Reviewed Original ResearchSuicide prevention treatmentsMinority stressBrief cognitive-behavioral therapyCognitive-behavioral therapyElevated suicide riskGender minority stressTransgender participantsCase formulationSuicide riskNegative eventsTransgender clientsSources of resilienceSuicide preventionEvidence-based modelTrained cliniciansStress themesSuicideTreatment sessionsPreventive treatmentTransgender peopleTransgender individualsExternal eventsGender dysphoriaTransgenderContent analysisBrain functional connectivity and anatomical features as predictors of cognitive behavioral therapy outcome for anxiety in youths
Zugman A, Ringlein G, Finn E, Lewis K, Berman E, Silverman W, Lebowitz E, Pine D, Winkler A. Brain functional connectivity and anatomical features as predictors of cognitive behavioral therapy outcome for anxiety in youths. Psychological Medicine 2025, 55: e91. PMID: 40125734, PMCID: PMC12080668, DOI: 10.1017/s0033291724003131.Peer-Reviewed Original ResearchConceptsCognitive-behavioral therapyConnectome predictive modelingWeeks of cognitive-behavioral therapyCognitive behavioural therapy outcomeResting-state functional magnetic resonance imagingFunctional magnetic resonance imagingBehaviour therapy outcomePediatric anxiety disordersBaseline anxiety severityBrain functional connectivityAnxiety disordersAnxiety severityPediatric anxietyAnxiety diagnosesAnxiety symptomsFunctional connectivityTherapy outcomeAnxietyFirst-line treatmentTreatment responseTreatment outcomesMagnetic resonance imagingPredictive of responseFirst-lineClinical outcomesGambling disorder and problematic pornography use: Does co-occurrence influence treatment outcome?
Mestre-Bach G, Potenza M, Granero R, Håkansson A, Gómez-Peña M, Perales I, Vicó À, Uríszar J, Fernández-Aranda F, Sánchez I, Jiménez-Murcia S. Gambling disorder and problematic pornography use: Does co-occurrence influence treatment outcome? Journal Of Behavioral Addictions 2025, 14: 465-479. PMID: 40116860, PMCID: PMC11974433, DOI: 10.1556/2006.2025.00023.Peer-Reviewed Original ResearchConceptsCognitive-behavioral therapyGambling disorderPornography useEmotion regulationGD severityTreatment outcomesCognitive-behavioral therapy approachCognitive-behavioral therapy sessionsTreatment outcomes of individualsCo-occurrence of GDCo-occurrenceMental health concernsImprove treatment adherenceBehavioral addictionsTreatment dropoutOutcomes of individualsWeekly sessionsTreatment adherencePsychopathologyGamblingSessionsDisordersAssociated with higher likelihoodRelapseImpulseState of the Science: Hoarding Disorder and Its Treatment
Tolin D, Worden B, Levy H. State of the Science: Hoarding Disorder and Its Treatment. Behavior Therapy 2025, 56: 667-679. PMID: 40541370, DOI: 10.1016/j.beth.2025.03.002.Peer-Reviewed Original ResearchConceptsCognitive-behavioral therapyCognitive-behavioral modelHoarding disorderReview current theoretical modelsAddiction modelEvidence of efficacyBiopsychosocial modelAttachment modelDisordersCultural modificationsAddictionState-of-the-scienceResearch directionsState-of-the-science reviewTreatmentInterventionModerators of digital cognitive-behavioral therapy for youth with sickle cell disease pain: secondary analysis of a randomized controlled trial.
Palermo T, Srinakarin K, Zhou C, Lalloo C, Dampier C, Zempsky W, Badawy S, Bakshi N, Ko Y, Nishat F, Stinson J. Moderators of digital cognitive-behavioral therapy for youth with sickle cell disease pain: secondary analysis of a randomized controlled trial. Pain 2025 PMID: 40085012, DOI: 10.1097/j.pain.0000000000003583.Peer-Reviewed Original ResearchCognitive-behavioral therapyRandomized controlled trialsEducation controlSymptoms of sickle cell diseaseDifferential intervention effectsSickle cell disease painPain intensity outcomesChronic SCD painParental psychological distressFamily-focused strategiesSecondary data analysisEffectiveness of cognitive-behavioral therapyModerate treatment effectsIntervention effectsPsychological distressEffect modificationPain outcomesIntensity outcomesSecondary analysisParental distressControlled trialsFamily factorsSickle cell diseaseFamily characteristicsPotential moderatorsRandomised controlled trial of LGBTQ-affirmative cognitive-behavioural therapy for sexual minority women’s minority stress, mental health and hazardous drinking: Project EQuIP protocol
Pachankis J, Chiaramonte D, Scheer J, Ankrum H, Eisenstadt B, Hobbs R, Baldwin H, Kidd J, Witkiewitz K, Esserman D, Plourde K, Drabble L, Hughes T. Randomised controlled trial of LGBTQ-affirmative cognitive-behavioural therapy for sexual minority women’s minority stress, mental health and hazardous drinking: Project EQuIP protocol. BMJ Open 2025, 15: e086738. PMID: 40032395, PMCID: PMC11877267, DOI: 10.1136/bmjopen-2024-086738.Peer-Reviewed Original ResearchConceptsCognitive-behavioral therapy interventionSexual minority womenMinority womenHazardous drinkingMinority stressRandomised controlled trialsProportion of heavy drinking daysSessions of supportive counselingComorbid mental health problemsRisk of hazardous drinkingCognitive-behavioral therapyHeavy drinking daysHazardous alcohol useHuman Subjects CommitteeMental health comorbiditiesMental health problemsAnxiety disordersAnxious symptomsDrinking daysEvidence-based interventionsSupportive counselingControlled trialsStress copingComorbid depression/anxietyDisproportionate riskPredictive Validity and Treatment Sensitivity of the Death-Implicit Association Test (D-IAT) During Inpatient Treatment and Across a 6-Month Follow-Up Period
Levy H, Lord K, Rice T, Sain K, Stubbing J, Diefenbach G, Tolin D. Predictive Validity and Treatment Sensitivity of the Death-Implicit Association Test (D-IAT) During Inpatient Treatment and Across a 6-Month Follow-Up Period. Cognitive Therapy And Research 2025, 1-10. DOI: 10.1007/s10608-024-10564-z.Peer-Reviewed Original ResearchDeath Implicit Association TestSuicidal thoughtsInpatient treatmentFrequency of suicidal behaviorAssociation TestCognitive-behavioral therapyHigh risk of suicidePsychiatric inpatient unitTreatment sensitivitySample of inpatientsRisk of suicideImplicit cognitionSuicidal behaviorSuicide riskPredictive validitySuicide preventionDetect treatment effectsInpatient unitSuicideFollow-up periodPeriod post-dischargeInpatientsTreatment effectsThoughtsInpatient admissionsThe effect of inpatient brief cognitive-behavioral therapy for suicide prevention on post-discharge emergency department utilization: Secondary analysis of a randomized clinical trial
Diefenbach G, Collett S, Black S, Rudd M, Gueorguieva R, Tolin D. The effect of inpatient brief cognitive-behavioral therapy for suicide prevention on post-discharge emergency department utilization: Secondary analysis of a randomized clinical trial. General Hospital Psychiatry 2025, 93: 73-79. PMID: 39837259, DOI: 10.1016/j.genhosppsych.2025.01.007.Peer-Reviewed Original ResearchConceptsSubstance use disordersBrief cognitive-behavioral therapyCognitive-behavioral therapyED visitsSuicide preventionSecondary analysisEmergency departmentSuicide-related ED visitsHistory of suicide attemptsEmergency department utilizationElectronic medical record reviewPost-discharge emergency departmentMedical record reviewED utilizationPsychiatric readmissionTreatment effectsSuicide attemptsUse disorderRecord reviewSelf-reportRandomized clinical trialsGeneralized linear modelVisitsSuicidePost-discharge ED visits
2024
Cognitive Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder With Obesity: A Randomized Controlled Trial
Grilo C, Ivezaj V, Tek C, Yurkow S, Wiedemann A, Gueorguieva R. Cognitive Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder With Obesity: A Randomized Controlled Trial. American Journal Of Psychiatry 2024, 182: 209-218. PMID: 39659158, PMCID: PMC11786997, DOI: 10.1176/appi.ajp.20230982.Peer-Reviewed Original ResearchCognitive-behavioral therapyBinge-eating disorderEffectiveness of cognitive-behavioral therapyBinge-eating remission ratesEating-disorder psychopathologyCognitive behavioral therapyEvidence-based treatmentsRemission ratePercent weight lossHigher remission ratesBinge-eating frequencyBehavioral therapyPosttreatment assessmentLisdexamfetamineRandomized controlled trialsHeightened ratesCostly public health problemIntention-to-treat ratesFunctional impairmentWeight lossControlled trialsDisordersPosttreatmentIndividualized treatmentMixed modelsCurrent Advances in Behavioral Addictions: From Fundamental Research to Clinical Practice
Brand M, Antons S, Bőthe B, Demetrovics Z, Fineberg N, Jimenez-Murcia S, King D, Mestre-Bach G, Moretta T, Müller A, Wegmann E, Potenza M. Current Advances in Behavioral Addictions: From Fundamental Research to Clinical Practice. American Journal Of Psychiatry 2024, 182: 155-163. PMID: 39659159, DOI: 10.1176/appi.ajp.20240092.Peer-Reviewed Original ResearchBehavioral addictionsAddictive behaviorsGaming disorderDisorders due to addictive behaviorsCompulsive sexual behavior disorderCompulsive buying-shopping disorderAttention deficit hyperactivity disorderCognitive-behavioral therapyBuying-shopping disorderSexual behavior disorderEmpirical supportInternet gaming disorderDeficit hyperactivity disorderPoor treatment outcomesResearch to clinical practiceDSM-5Gambling disorderICD-11Psychiatric disordersHyperactivity disorderBehavior problemsBehavioral disordersAddictionDiagnostic instrumentsEfficacious treatmentChanges in hoarding-related beliefs and associated neural changes during a simulated discarding task after cognitive-behavioral treatment for hoarding disorder
Knowles K, Stevens M, Levy H, Tolin D. Changes in hoarding-related beliefs and associated neural changes during a simulated discarding task after cognitive-behavioral treatment for hoarding disorder. Journal Of Psychiatric Research 2024, 180: 473-481. PMID: 39547046, PMCID: PMC11606758, DOI: 10.1016/j.jpsychires.2024.11.017.Peer-Reviewed Original ResearchCognitive-behavioral therapyHoarding-related beliefsFunctional magnetic resonance imagingHoarding disorderNeural activityMaladaptive beliefsCourse of CBTGroup cognitive-behavioral therapyLeft anterior cingulate cortexLeft middle frontal gyrusAssociated with cognitive changesCognitive-behavioral treatmentAssociated with increased activityAnterior ventral insulaAnterior cingulate cortexMiddle frontal gyrusInferior temporal lobeLeft middle insulaCognitive-behavioralAssociated with specific changesFrontal gyrusCingulate cortexMiddle insulaNeural regionsVentral insulaIntegrative Strong Body and Mind Training for Sickle Cell Disease (I-STRONG)-an Interdisciplinary, Multicomponent Treatment Approach for Pediatric Chronic SCD Pain
Sil S, Mooney J, Adkins T, Sinha C, Nunez M, Thomas S, Beasley K, Lang A, Murphy B, Akintobi T, Williams J, Batts K, Kurzhals A, Bakshi N, Kesar T, Myer G, Quinn C, Dampier C, Crosby L, Kashikar-Zuck S. Integrative Strong Body and Mind Training for Sickle Cell Disease (I-STRONG)-an Interdisciplinary, Multicomponent Treatment Approach for Pediatric Chronic SCD Pain. Blood 2024, 144: 291. DOI: 10.1182/blood-2024-209083.Peer-Reviewed Original ResearchChronic SCD painChronic painExercise trainingCognitive-behavioral therapyPhysical therapyPain intensityPain managementPatient Global ImpressionEvidence-based interdisciplinary approachADAPT-ITT modelIntegrative therapiesSemi-structured qualitative interviewsCommunity advisory boardSickle cell diseaseCommunity engagementEvidence-based interventionsSickle cell disease painPediatric sickle cell diseaseFollow-upChronic pain managementImpaired quality of lifeMulticomponent treatment programQuality of lifeCaregiver perspectivesIntervention fidelityImplementing LGBTQ-affirmative cognitive-behavioral therapy: implementation strategies across five clinical trials
Harkness A, Soulliard Z, Layland E, Behari K, Rogers B, Bharat B, Safren S, Pachankis J. Implementing LGBTQ-affirmative cognitive-behavioral therapy: implementation strategies across five clinical trials. Implementation Science Communications 2024, 5: 124. PMID: 39501392, PMCID: PMC11539333, DOI: 10.1186/s43058-024-00657-x.Peer-Reviewed Original ResearchCognitive-behavioral therapyImplementation strategiesEvidence-based treatmentsBehavioral health concernsPublic health benefitsComplex interventionsLGBTQ individualsReal-world settingsReporting toolHealth concernSurvey responsesHealth benefitsLevel of resourcesInterventionTrialsModerate priorityPriorityClinical trialsIndividualsImplementationDependent strategiesFindingsA Pilot Trial of an LGBTQ-Affirmative Cognitive-Behavioral Therapy for Transgender and Gender Expansive Individuals’ Mental, Behavioral, and Sexual Health
Lelutiu-Weinberger C, Filimon M, Chiaramonte D, Leonard S, Dogaru B, Pana E, Pruneanu C, Pachankis J. A Pilot Trial of an LGBTQ-Affirmative Cognitive-Behavioral Therapy for Transgender and Gender Expansive Individuals’ Mental, Behavioral, and Sexual Health. Behavior Therapy 2024, 56: 723-737. PMID: 40541374, PMCID: PMC12181672, DOI: 10.1016/j.beth.2024.10.005.Peer-Reviewed Original ResearchCognitive-behavioral therapyMinority stressAnxiety symptomsPreliminary efficacyTGE individualsCisgender sexual minorityTherapeutic allianceTrained psychologistsEvidence-based interventionsBaseline to follow-upTreatment relevanceRisk mechanismsImprove psychosocial healthGender-expansive individualsTGE youthSexual minoritiesAnxietyNorth American contextDepressionRandomized controlled trialsContext of RomaniaPsychosocial healthHealth outcomesFollow-upExit interviewsCost-effectiveness of screening and treating alcohol use and depression among people living with HIV in Zimbabwe: a mathematical modeling study
Su J, Yeo Y, Jeetoo M, Morojele N, Francis J, Shenoi S, Braithwaite R. Cost-effectiveness of screening and treating alcohol use and depression among people living with HIV in Zimbabwe: a mathematical modeling study. BMC Medicine 2024, 22: 481. PMID: 39428460, PMCID: PMC11492560, DOI: 10.1186/s12916-024-03674-8.Peer-Reviewed Original ResearchConceptsCognitive-behavioral therapyBackgroundAlcohol use disorderTreating alcohol useCompared to baselineLong-acting PrEPDepressive disorderTreat AUDUse disorderMDDMDD screeningAlcohol usePHQ-9Quality-adjusted life yearsAUDCost-effectiveness of screeningSub-Saharan African settingDisordersImpact of screeningIntervention costsHIV infectionHIV transmissionHIV reductionInterventionHIV outcomesHIV epidemic
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