2025
Is there harm in behavioral weight loss for binge-eating disorder: Controlled comparison to cognitive behavioral therapy
Grilo C, Yurkow S, White M, Lydecker J, Ivezaj V. Is there harm in behavioral weight loss for binge-eating disorder: Controlled comparison to cognitive behavioral therapy. General Hospital Psychiatry 2025, 96: 72-74. PMID: 40543449, DOI: 10.1016/j.genhosppsych.2025.06.005.Peer-Reviewed Original ResearchRandomized Controlled Trial of Weight Management Versus Weight Management With Concurrent Cognitive‐Behavioral Therapy for Binge‐Eating Disorder in US Veterans With High Weight
Masheb R, Buta E, Snow J, Munro L, Lawless M, Abel E, McWain N, Marsh A, Cary A, Grilo C, Raffa S, Ruser C. Randomized Controlled Trial of Weight Management Versus Weight Management With Concurrent Cognitive‐Behavioral Therapy for Binge‐Eating Disorder in US Veterans With High Weight. International Journal Of Eating Disorders 2025 PMID: 40485646, DOI: 10.1002/eat.24476.Peer-Reviewed Original ResearchDSM-5 binge-eating disorderBinge-eating disorderDSM-5Cognitive-behavioral therapyEating-disorder treatmentRemission rateUS military veteransBinge-eating frequencyMilitary veteransCBTVeteran populationShape-relatedVeteransWeight managementPost-treatmentWeight management programUS veteransMixed-effects modelsDisordersRandomized controlled trialsClinical Trials Registry numberPsychopathologyBinge-eatingWeight lossClinical guidanceIs there harm in behavioral lifestyle weight management for binge-eating disorder in patients with obesity: Findings from a randomized controlled trial
Grilo C, Ivezaj V, Yurkow S, Lydecker J. Is there harm in behavioral lifestyle weight management for binge-eating disorder in patients with obesity: Findings from a randomized controlled trial. Journal Of Psychosomatic Research 2025, 195: 112169. PMID: 40516275, DOI: 10.1016/j.jpsychores.2025.112169.Peer-Reviewed Original ResearchEating-disorder psychopathologyBinge-eating disorderIncreased symptomsSymptoms of binge eatingRandomized controlled trialsBinge-eating frequencyBinge eatingPsychopathologyRandomized to placeboBinge-eatingWeight managementPlaceboHeterogeneity of outcomesDisordersParticipantsPosttreatmentSecondary analysisFrequency of casesSymptomsClinical contextIndividual levelObesityControlled trialsSmall magnitudePatientsCombining Cognitive‐Behaviour Therapy With Mindfulness Training in a Digital Intervention for Binge Eating Disorder: A Single‐Session Pilot Trial
Sala M, Roos C, Kober H, Bricker J, Stern C, Plutchik J, John M, Haeny A, Feldman J, Aslan M, Hay J, Forman E. Combining Cognitive‐Behaviour Therapy With Mindfulness Training in a Digital Intervention for Binge Eating Disorder: A Single‐Session Pilot Trial. European Eating Disorders Review 2025 PMID: 40350587, DOI: 10.1002/erv.3204.Peer-Reviewed Original ResearchBinge Eating ScaleBinge eating episodesCognitive behavioral therapyEating disorder symptomsBinge-eating disorderEDE-QDisorder symptomsMindfulness trainingEating episodesGlobal eating disorder symptomsBinge Eating Scale scoresEating Disorder Examination QuestionnaireReducing binge eatingCognitive-behavioral therapyBinge eating disorderSingle-session interventionEnglish-speaking adultsCognitive-behavioralBinge eatingBehavioral therapyEating ScaleExamination QuestionnaireEating disordersEpisodic questionsDigital interventionsPreferences for Lisdexamfetamine vs Cognitive-Behavioral Therapy for Binge-Eating Disorder: Correlates and Outcomes.
Yurkow S, Ivezaj V, Pittman B, Grilo C. Preferences for Lisdexamfetamine vs Cognitive-Behavioral Therapy for Binge-Eating Disorder: Correlates and Outcomes. The Journal Of Clinical Psychiatry 2025, 86 PMID: 40338285, DOI: 10.4088/jcp.24m15552.Peer-Reviewed Original ResearchConceptsBinge-eating disorderTreatment preferencesModerate treatment outcomePatient treatment preferencesCognitive-behavioral therapyEffects of treatment preferenceTest main effectsCognitive-behavioralNo significant interaction effectsInteraction effectsBehavioral therapySignificant interaction effectCBTModerate outcomeEfficacious treatmentMain effectLisdexamfetamineTreatment outcomesParticipants' preferencesEffective interventionsEffects of treatmentDisordersRandomized controlled trialsNo preferenceLDXLifestyle behavioral weight‐loss treatment for binge‐eating disorder in patients with obesity: where's the harm?
Yurkow S, Ivezaj V, Grilo C. Lifestyle behavioral weight‐loss treatment for binge‐eating disorder in patients with obesity: where's the harm? Obesity 2025, 33: 1058-1066. PMID: 40342236, PMCID: PMC12119222, DOI: 10.1002/oby.24289.Peer-Reviewed Original ResearchConceptsBinge-eating disorderED psychopathologyWeight loss treatmentExacerbate eating disordersBinge-eating frequencyPsychopathology scoresBinge eatingSymptoms of binge eatingBehavioral weight loss treatmentIncreased symptomsEating disordersPsychopathologyFollow-upDisordersPosttreatmentHeterogeneity of outcomesEatingSecondary analysisFrequency of casesCoexisting obesityClinical contextParticipantsIndividual levelBingeObesityRapid response to behavioral/pharmacological obesity treatments for binge‐eating disorder predicts better clinical outcomes
Lydecker J, Gueorguieva R, Grilo C. Rapid response to behavioral/pharmacological obesity treatments for binge‐eating disorder predicts better clinical outcomes. Obesity 2025, 33: 1067-1075. PMID: 40265670, DOI: 10.1002/oby.24292.Peer-Reviewed Original ResearchConceptsBinge-eating disorderBinge-eating remissionEating-disorder psychopathologyAssociated with greater reductionsObesity treatmentCo-occurring obesityBinge-eating frequencyClinical trial testingBehavioral therapyNon-rapid responseGreater reductionsPercent weight lossNaltrexone/bupropionRandomized clinical trial testingDisordersPrognostic significanceParticipantsPosttreatmentClinical characteristicsPrognostic indicatorClinical outcomesMetabolic outcomesResponse effectMetabolic variablesObesity interventionsCross‐Cultural Validation of the Binge Eating Disorder Screener‐7 (BEDS‐7) Across 42 Countries
Gewirtz‐Meydan A, Spivak‐Lavi Z, Kraus S, Nagy L, Koós M, Demetrovics Z, Potenza M, Ballester‐Arnal R, Batthyány D, Bergeron S, Billieux J, Briken P, Burkauskas J, Cárdenas‐López G, Carvalho J, Castro‐Calvo J, Chen L, Ciocca G, Corazza O, Csako R, Fernandez D, Fernandez E, Fujiwara H, Fuss J, Gabrhelík R, Gjoneska B, Gola M, Grubbs J, Hashim H, Islam S, Ismail M, Jiménez‐Martínez M, Jurin T, Kalina O, Klein V, Költő A, Lee C, Lee S, Lewczuk K, Lin C, Lochner C, López‐Alvarado S, Lukavská K, Mayta‐Tristán P, Miller D, Orosová O, Orosz G, Team S, Chang H, Park K, Ponce F, Quintana G, Garzola G, Ramos‐Diaz J, Rigaud K, Rousseau A, De Tubino Scanavino M, Schulmeyer M, Sharan P, Shibata M, Shoib, Sigre‐Leirós V, Sniewski L, Spasovski O, Steibliene V, Stein D, Strizek J, Ünsal B, Vaillancourt‐Morel M, Van Hout M, Bőthe B. Cross‐Cultural Validation of the Binge Eating Disorder Screener‐7 (BEDS‐7) Across 42 Countries. International Journal Of Eating Disorders 2025, 58: 926-938. PMID: 40040591, PMCID: PMC12067514, DOI: 10.1002/eat.24365.Peer-Reviewed Original ResearchBinge-eating disorderTests of measurement invarianceDiverse community sampleBinge-eating disorder symptomsCross-sectional online studyMeasures of sexualityConfirmatory factor analysisCross-cultural validityPrimary care settingSexual orientationBED symptomsSexual orientation groupsCommunity sampleFactorial invarianceItem interceptsResidual invarianceBEDS-7Measurement invarianceSubstance useDiverse cultural contextsAdequate reliabilityCriterion validityModerate criterion validityMental healthOnline studyAcceptance-based skill acquisition and cognitive reappraisal in a culturally responsive treatment for binge eating in adolescence
Kamody R, Thurston I, Burton E. Acceptance-based skill acquisition and cognitive reappraisal in a culturally responsive treatment for binge eating in adolescence. 2025, 88-105. DOI: 10.4324/9781003607625-7.Peer-Reviewed Original ResearchDialectical behavior therapyBinge-eating disorderDBT skillsPotential mechanisms of changeSubthreshold binge-eating disorderCulturally responsive treatmentSkills group interventionSkill acquisitionMechanisms of changeCognitive reappraisalBinge-eating behaviorBehavioral therapyResponse treatmentCognitive strategiesNegative emotionsRadical acceptanceGroup interventionEmotional overeatingOver-interventionAdolescentsScale scoreHigh-risk behaviorsScalable interventionsIntervention acceptabilityPost-intervention
2024
The Need to Increase Help‐Seeking for Eating Disorders in General and Binge‐Eating Disorder Specifically: Commentary on Ali et al.'s (2024) Meta‐Analysis
Lydecker J. The Need to Increase Help‐Seeking for Eating Disorders in General and Binge‐Eating Disorder Specifically: Commentary on Ali et al.'s (2024) Meta‐Analysis. International Journal Of Eating Disorders 2024, 58: 514-517. PMID: 39723480, PMCID: PMC11893227, DOI: 10.1002/eat.24364.Peer-Reviewed Original ResearchCognitive Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder With Obesity: A Randomized Controlled Trial
Grilo C, Ivezaj V, Tek C, Yurkow S, Wiedemann A, Gueorguieva R. Cognitive Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder With Obesity: A Randomized Controlled Trial. American Journal Of Psychiatry 2024, 182: 209-218. PMID: 39659158, PMCID: PMC11786997, DOI: 10.1176/appi.ajp.20230982.Peer-Reviewed Original ResearchCognitive-behavioral therapyBinge-eating disorderEffectiveness of cognitive-behavioral therapyBinge-eating remission ratesEating-disorder psychopathologyCognitive behavioral therapyEvidence-based treatmentsRemission ratePercent weight lossHigher remission ratesBinge-eating frequencyBehavioral therapyPosttreatment assessmentLisdexamfetamineRandomized controlled trialsHeightened ratesCostly public health problemIntention-to-treat ratesFunctional impairmentWeight lossControlled trialsDisordersPosttreatmentIndividualized treatmentMixed modelsDevelopment and preliminary validation of a modified Food Craving Inventory for Pregnancy (FCI-P) in U.S. military active-duty Service women
Thompson K, White M, Schrag R, Lavender J, Bauman V, Mains A, Rioux S, Spinner H, Thorstad I, Klein D, Haigney M, Tanofsky-Kraff M. Development and preliminary validation of a modified Food Craving Inventory for Pregnancy (FCI-P) in U.S. military active-duty Service women. Appetite 2024, 203: 107677. PMID: 39288884, DOI: 10.1016/j.appet.2024.107677.Peer-Reviewed Original ResearchFood Craving InventoryFour-factor structureBinge-eating disorderSeries of confirmatory factor analysesGood-to-excellent internal consistencyMeasures of cravingEating-related measuresDisinhibited eating behaviorsPoor model fitConfirmatory factor analysisModel fitPregnant womenFood cravingsConvergent validityPsychometric propertiesCross-loadingsMultiple subscalesCravingEating behaviorsInternal consistencySample of pregnant womenFactor analysisBehavior scoresEating behavior scoresDisordersLisdexamfetamine maintenance treatment for binge-eating disorder following successful treatments: randomized double-blind placebo-controlled trial
Grilo C, Ivezaj V, Yurkow S, Tek C, Wiedemann A, Gueorguieva R. Lisdexamfetamine maintenance treatment for binge-eating disorder following successful treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2024, 54: 3334-3344. PMID: 39258475, PMCID: PMC11496227, DOI: 10.1017/s003329172400148x.Peer-Reviewed Original ResearchEating-disorder psychopathologyBinge-eating disorderMaintenance treatmentAcute treatmentBinge-eating remission ratesCognitive-behavioral therapyEfficacy of lisdexamfetamineSignificant weight gainDouble-blind placebo-controlled trialAcute respondersLisdexamfetamine treatmentPsychopathological outcomesPosttreatment assessmentLisdexamfetaminePlacebo-controlled trialRandomized double-blind placebo-controlled trialSingle-site trialAssociated with significant weight lossPsychopathologyBinge-eatingRemission rateWeight lossPlaceboRelapse rateControl researchExploring Dietary Restraint as a Mediator of Behavioral and Cognitive‐Behavioral Treatments on Outcomes for Patients With Binge‐Eating Disorder With Obesity
Grilo C, Pittman B. Exploring Dietary Restraint as a Mediator of Behavioral and Cognitive‐Behavioral Treatments on Outcomes for Patients With Binge‐Eating Disorder With Obesity. International Journal Of Eating Disorders 2024, 57: 2475-2481. PMID: 39247962, PMCID: PMC11631662, DOI: 10.1002/eat.24288.Peer-Reviewed Original ResearchCognitive-behavioral therapyBehavioral weight lossBinge-eating disorderBinge eatingWeight loss outcomesCognitive-behavioral treatmentMediation of behaviorEDE-Q restraintPost-treatmentCognitive-behavioralRestraint ScaleDietary restraintBingeMediation effectEatingEffects of treatmentTreatment effectsDisordersRandomized controlled trialsWeight lossMonths of treatmentHypothesis-testingSecondary analysisRestraintBinge-eatingTreatment of Eating Disorders: Current Status, Challenges, and Future Directions
Grilo C. Treatment of Eating Disorders: Current Status, Challenges, and Future Directions. Annual Review Of Clinical Psychology 2024, 20: 97-123. PMID: 38211625, DOI: 10.1146/annurev-clinpsy-080822-043256.Peer-Reviewed Original ResearchAnorexia nervosaBinge-eating disorderBulimia nervosaEating disordersAdaptive treatment designsPsychological treatmentTreatment researchNervosaTreatment designDisordersBulimiaPharmacological optionsAnorexiaEnhanced outcomesExpected final online publication dateFirst-line approachOnline publication dateMedicationFirst-lineClinical guidanceAnnual ReviewAlternative treatmentRevised estimatesPatientsTreatmentNeural Responses to Auditory Food Stimuli Following Cognitive Behavioral Therapy for Binge‐Eating Disorder
Chao A, Agarwal K, Zhou Y, Grilo C, Gur R, Joseph P, Shinohara R, Richmond T, Wadden T. Neural Responses to Auditory Food Stimuli Following Cognitive Behavioral Therapy for Binge‐Eating Disorder. International Journal Of Eating Disorders 2024, 57: 1911-1923. PMID: 38953334, PMCID: PMC11483217, DOI: 10.1002/eat.24244.Peer-Reviewed Original ResearchCognitive behavioral therapyFunctional magnetic resonance imagingBlood oxygen level-dependentWait-list controlBinge-eating disorderBehavioral therapyFunctional magnetic resonance imaging sessionNeutral-relaxing cuesReward-based eating driveReward-related regionsReducing binge eatingMeasured BOLD responsesReward regionsBinge eatingBinge-eating episodesFood cuesEating drivePersonalized scriptsBOLD responseRandomized controlled trialsNeural responsesFood-stimuliBinge-eatingCuesMagnetic resonance imagingOvervaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder
Grilo C, Ivezaj V, Gueorguieva R. Overvaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder. International Journal Of Eating Disorders 2024, 57: 1268-1273. PMID: 38321617, PMCID: PMC11093697, DOI: 10.1002/eat.24141.Peer-Reviewed Original ResearchOvervaluation of shape/weightEating-disorder psychopathologyBinge-eating disorderEating Disorder Examination interviewBeck Depression InventoryWeight loss treatmentClinical overvaluationBinge-eating frequencyDiagnostic specifierBinge eatingNon-abstinenceExamination interviewDepression InventoryShape/weightDepression scoresFollow-upPsychopathologyAbstinenceBingeDepressionClinical implicationsDepression 1PosttreatmentDisordersOvervaluationReliability of the original and brief versions of the Eating Disorder Examination in binge‐eating disorder
Lydecker J, Ivezaj V, Wiedemann A, Kerrigan S, Grilo C. Reliability of the original and brief versions of the Eating Disorder Examination in binge‐eating disorder. Obesity 2024, 32: 702-709. PMID: 38311600, PMCID: PMC10965370, DOI: 10.1002/oby.23993.Peer-Reviewed Original ResearchEating Disorder ExaminationEating Disorder Examination interviewEating-disorder psychopathologyBinge-eating disorderInternal consistencyDoctoral-levelIndicators of loss of controlInterrater reliabilityLoss of controlBinge eatingBinge-eating episodesPsychological treatmentPsychometric propertiesPsychometric studyTests of reliabilityBehavioral indicatorsAssessed adultsClinical researchPsychopathologyEatingRatersDisordersAudio-recordedAdultsPatient groupThe children of parents who receive treatment for binge‐eating disorder experience improvements in disordered eating
Lydecker J, Ozbardakci E, Grilo C. The children of parents who receive treatment for binge‐eating disorder experience improvements in disordered eating. International Journal Of Eating Disorders 2024, 57: 745-751. PMID: 38308384, PMCID: PMC10947894, DOI: 10.1002/eat.24153.Peer-Reviewed Original ResearchBinge-eating disorderBinge eatingDisordered eating behaviorsEating behaviorsSecretive eatingParent changesDisordered eatingAssociated with disordered eating behaviorsEating-disorder psychopathologyEnd-of-treatment assessmentParental eating disordersAssociated with changesChildren of parentsCross-sectional workChild disordered eating behaviorsBinge-eating frequencyEating disordersSchool-aged childrenParental treatmentUntreated family membersParent medicationLongitudinal researchBingeBaseline assessmentEating
2023
The Relationship of Self-identified Weight Status With Perceived Mental and Physical Health
Hamilton A, Smith S, Lydecker J. The Relationship of Self-identified Weight Status With Perceived Mental and Physical Health. Journal Of Psychiatric Practice 2023, 29: 430-438. PMID: 37948168, PMCID: PMC10653675, DOI: 10.1097/pra.0000000000000744.Peer-Reviewed Original ResearchConceptsOW/OBBinge-eating disorderDisorder psychopathologyPhysical healthMental healthStudy groupBulimia nervosaOW/OB groupBN groupOverweight/obesityFuture clinical researchOB groupWeight statusObesityClinical researchBED groupOverweightDepressionHealthPsychopathologyDisordersGroupOBLow levelsAnalysis of variance
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