2025
Psychometric properties of the Reward Deficiency Syndrome Questionnaire among a non-clinical sample and its relationship with the characteristics of potentially addictive behaviors
Kotyuk E, Demetrovics Z, Urbán R, Czakó A, Blum K, Griffiths M, Potenza M, Efrati Y. Psychometric properties of the Reward Deficiency Syndrome Questionnaire among a non-clinical sample and its relationship with the characteristics of potentially addictive behaviors. Addictive Behaviors Reports 2025, 21: 100598. PMID: 40248688, PMCID: PMC12005299, DOI: 10.1016/j.abrep.2025.100598.Peer-Reviewed Original ResearchReward Deficiency SyndromeCompulsive buying-shopping disorderInternet gaming disorderAddictive behaviorsBehavioral addictionsGambling disorderDevelopment of addictive behaviorsBuying-shopping disorderNon-clinical samplePotential behavioral addictionsProblematic substance useAssociated with anxietyIsraeli young adultsPsychometrically sound instrumentNatural rewardsCompulsive personalityFactor structureGaming disorderProblematic behaviorsSubstance useSocial media usePersonal characteristicsPsychological featuresSound instrumentHebrew versionGambling disorder and problematic pornography use: Does co-occurrence influence treatment outcome?
Mestre-Bach G, Potenza M, Granero R, Håkansson A, Gómez-Peña M, Perales I, Vicó À, Uríszar J, Fernández-Aranda F, Sánchez I, Jiménez-Murcia S. Gambling disorder and problematic pornography use: Does co-occurrence influence treatment outcome? Journal Of Behavioral Addictions 2025, 14: 465-479. PMID: 40116860, PMCID: PMC11974433, DOI: 10.1556/2006.2025.00023.Peer-Reviewed Original ResearchConceptsCognitive-behavioral therapyGambling disorderPornography useEmotion regulationGD severityTreatment outcomesCognitive-behavioral therapy approachCognitive-behavioral therapy sessionsTreatment outcomes of individualsCo-occurrence of GDCo-occurrenceMental health concernsImprove treatment adherenceBehavioral addictionsTreatment dropoutOutcomes of individualsWeekly sessionsTreatment adherencePsychopathologyGamblingSessionsDisordersAssociated with higher likelihoodRelapseImpulseCurrent interpretations of the I-PACE model of behavioral addictions
Brand M, Müller A, Wegmann E, Antons S, Brandtner A, Müller S, Stark R, Steins-Loeber S, Potenza M. Current interpretations of the I-PACE model of behavioral addictions. Journal Of Behavioral Addictions 2025, 14: 1-17. PMID: 40063161, PMCID: PMC11974429, DOI: 10.1556/2006.2025.00020.Peer-Reviewed Original ResearchConceptsI-PACE modelI-PACEBehavioral addictionsInteraction of Person-Affect-Cognition-ExecutionBehavioral addiction researchCue-reactivityDesire thinkingCompulsive behaviorsExecutive functionAddictive behaviorsNegative reinforcementAddiction researchPermissive beliefsAddiction theoryAddiction fieldSelf-controlAddictionCravingEmpirical findingsTheory buildingClinical careStimulate researchGratificationBehaviorContext of changesTransdiagnostic study of dynamic brain activity and connectivity among people with gambling and internet gaming disorders DYNAMIC BRAIN ACTIVITY IN GD AND IGD
Zhou H, He Y, Liu L, Yin J, Xiong A, Leong K, Wu A, Potenza M. Transdiagnostic study of dynamic brain activity and connectivity among people with gambling and internet gaming disorders DYNAMIC BRAIN ACTIVITY IN GD AND IGD. International Journal Of Clinical And Health Psychology 2025, 25: 100547. PMID: 39944189, PMCID: PMC11815891, DOI: 10.1016/j.ijchp.2025.100547.Peer-Reviewed Original ResearchInternet gaming disorder groupInternet gaming disorderIGD participantsFunctional magnetic resonance imagingDynamic brain activityGambling disorderHC participantsBrain activityTransdiagnostic studiesFrontal gyrusLeft triangular inferior frontal gyrusFeatures of behavioral addictionsResting-state functional magnetic resonance imagingTriangular inferior frontal gyrusInferior frontal gyrusCombination of self-reportHealthy controlsPositive playBehavioral addictionsSelf-reported indicatorsNeural measuresGaming disorderDiagnostic groupsBrain connectivitySelf-report
2024
Current Advances in Behavioral Addictions: From Fundamental Research to Clinical Practice
Brand M, Antons S, Bőthe B, Demetrovics Z, Fineberg N, Jimenez-Murcia S, King D, Mestre-Bach G, Moretta T, Müller A, Wegmann E, Potenza M. Current Advances in Behavioral Addictions: From Fundamental Research to Clinical Practice. American Journal Of Psychiatry 2024, 182: 155-163. PMID: 39659159, DOI: 10.1176/appi.ajp.20240092.Peer-Reviewed Original ResearchBehavioral addictionsAddictive behaviorsGaming disorderDisorders due to addictive behaviorsCompulsive sexual behavior disorderCompulsive buying-shopping disorderAttention deficit hyperactivity disorderCognitive-behavioral therapyBuying-shopping disorderSexual behavior disorderEmpirical supportInternet gaming disorderDeficit hyperactivity disorderPoor treatment outcomesResearch to clinical practiceDSM-5Gambling disorderICD-11Psychiatric disordersHyperactivity disorderBehavior problemsBehavioral disordersAddictionDiagnostic instrumentsEfficacious treatmentPotential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review
Jalilian-Khave L, Kitaneh R, Ysrayl B, Borelli A, Funaro M, Potenza M, Angarita G. Potential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review. Addiction Neuroscience 2024, 14: 100190. PMID: 40083958, PMCID: PMC11902922, DOI: 10.1016/j.addicn.2024.100190.Peer-Reviewed Original ResearchImpulse control disordersSubstance use disordersControl disordersBehavioral addictionsTreating impulse control disordersVitamin DClinical studiesAddictive disordersSerotonergic circuitsExposure to vitamin DVitamin D deficiencyVitamin D levelsSymptom presenceDisordersPotential beneficial effectsJoanna Briggs InstituteD deficiencyPotential therapeutic mechanismAddictionD levelsWeb of ScienceTherapeutic mechanismQuality of studiesCochrane LibraryOvid MEDLINESpanish Validation of the Brief Pornography Screen Within a Clinical Sample of Individuals with Gambling Disorder
Tarragón E, Testa G, Granero R, Potenza M, Kraus S, Uríszar J, Chiclana Actis C, Fernández-Aranda F, Jiménez-Murcia S, Mestre-Bach G. Spanish Validation of the Brief Pornography Screen Within a Clinical Sample of Individuals with Gambling Disorder. Archives Of Sexual Behavior 2024, 53: 3759-3768. PMID: 39358592, DOI: 10.1007/s10508-024-02986-3.Peer-Reviewed Original ResearchBrief Pornography ScreenProblematic pornography useClinical sample of individualsConfirmatory factor analysisGambling disorderSample of individualsPsychometric propertiesLow self-directednessOne-factor solutionAdequate psychometric propertiesClinical samplesGeneral psychopathologySelf-directednessBehavioral addictionsImpulsive tendenciesConvergent validityPornography usePsychological distressScreening instrumentSpanish versionSpanish validationFactor analysisBriefDisordersIndividualsClinical characteristics associated with problematic pornography use among individuals seeking treatment for opioid use disorder
Stefanovics E, Kraus S, Madden L, Farnum S, Cannata E, Potenza M, Barry D. Clinical characteristics associated with problematic pornography use among individuals seeking treatment for opioid use disorder. Journal Of Behavioral Addictions 2024, 13: 938-946. PMID: 39298267, PMCID: PMC11737410, DOI: 10.1556/2006.2024.00037.Peer-Reviewed Original ResearchBrief Pornography ScreenOpioid use disorderPornography useOpioid use disorder treatmentUse disorderMeasures of substance useMeasures of impulsivityProblematic pornography useMinority of individualsNegative urgencyPositive urgencyPsychotic symptomsSelf-reported dataBehavioral addictionsGambling disorderPsychiatric disordersPsychiatric symptomsSensation-seekingEmotional labilitySelf-harmSubstance useDisordersOpioidIndividualsSymptomsGenes associated with cortical thickness alterations in behavioral addiction
Xie H, Wang Y, Zhu F, Zhang F, Wu B, Zhao Z, Gan R, Gong Q, Jia Z. Genes associated with cortical thickness alterations in behavioral addiction. Cerebral Cortex 2024, 34: bhae298. PMID: 39051658, DOI: 10.1093/cercor/bhae298.Peer-Reviewed Original ResearchConceptsBehavioral addictionsCortical thicknessBehavioral regulationPostcentral gyrusCompulsive reward-seeking behaviorReward-seeking behaviorDorsolateral prefrontal cortexDopamine D2 receptorsAllen Human Brain AtlasOrbital-frontal cortexCortical thickness alterationsHuman Brain AtlasAddiction phenotypesAddiction severityPrefrontal cortexD2 receptorsDopamine metabolismBrain areasNeurogenetic mechanismsAddictionThickness alterationsPrecuneusGyrusDopamineResponse to stimuliSpirituality and behavioural addictions: narrative review
Kanabar M, Kathiresan P, Elkholy H, Zonoozi A, Orsolini L, Long J, Farokhnia M, Bhad R, Butner J, Fonseca F, Phan V, Achab S, Potenza M. Spirituality and behavioural addictions: narrative review. BJPsych International 2024, 21: 59-61. PMID: 40291985, PMCID: PMC12022886, DOI: 10.1192/bji.2024.9.Peer-Reviewed Original ResearchIntrinsic connectivity demonstrates a shared role of the posterior cingulate for cue reactivity in both gambling and cocaine use disorders
Vaccaro A, Lacadie C, Potenza M. Intrinsic connectivity demonstrates a shared role of the posterior cingulate for cue reactivity in both gambling and cocaine use disorders. Addictive Behaviors 2024, 155: 108027. PMID: 38581751, PMCID: PMC11273263, DOI: 10.1016/j.addbeh.2024.108027.Peer-Reviewed Original ResearchConceptsCocaine use disorderPosterior cingulate cortexCue reactivityBehavioral addictionsUse disorderGambling disorderPosterior cingulatePosterior cingulate cortex connectivityHealthy comparison subjectsIntrinsic connectivity distributionIntervention developmentCocaine cuesFMRI taskAddictive disordersCingulate cortexComparison subjectsNeurobiological foundationsSad videosDecreased connectivityFunctional connectivityCocainePost hoc analysisAddictionRelevant to maintenanceGamblingAssociations Between Behavioral Addictions and Mental Health Concerns During the COVID-19 Pandemic: A Systematic Review and Meta-analysis
Alimoradi Z, Broström A, Potenza M, Lin C, Pakpour A. Associations Between Behavioral Addictions and Mental Health Concerns During the COVID-19 Pandemic: A Systematic Review and Meta-analysis. Current Addiction Reports 2024, 11: 565-587. DOI: 10.1007/s40429-024-00555-1.Peer-Reviewed Original ResearchMental health problemsHealth problemsSystematic reviewBehavioral addictionsMeta-analysisAssociated with more mental health problemsCOVID-19 pandemicMental health concernsMagnitude of associationReviewThe COVID-19 pandemicPreferred Reporting ItemsNewcastle Ottawa ScaleStudy's primary aimISI Web of KnowledgeFisher's z scoresWeb of KnowledgeHealthcare providersSources of heterogeneityMental distressElevated mental distressReporting ItemsOttawa ScaleInternet-related behaviorsInvestigate associationsSecondary aimInhibitory Control in Gambling Disorder, Internet Gaming Disorder, and Compulsive Sexual Behavior Disorder/Problematic Pornography Use: a Review of the Last 5 Years
Mestre-Bach G, Potenza M. Inhibitory Control in Gambling Disorder, Internet Gaming Disorder, and Compulsive Sexual Behavior Disorder/Problematic Pornography Use: a Review of the Last 5 Years. Current Behavioral Neuroscience Reports 2024, 11: 64-77. DOI: 10.1007/s40473-024-00272-z.Peer-Reviewed Original ResearchInternet gaming disorderImpaired inhibitory controlInhibitory controlGambling disorderBehavioral addictionsPornography useStudies of inhibitory controlComponents of executive functionStop-signal task performanceStop-signal taskGoal-directed behaviorTransdiagnostic factorExecutive functionIrrelevant responsesGaming disorderMental disordersTask performanceStroopDisordersAddictionHeterogeneous resultsTaskControl constructsNarrative reviewCompulsionMental health professionals' use of the ICD-11 classification of impulse control disorders and behavioral addictions: An international field study
Fuss J, Keeley J, Stein D, Rebello T, García J, Briken P, Robles R, Matsumoto C, Abé C, Billieux J, Grant J, Kraus S, Lochner C, Potenza M, Reed G. Mental health professionals' use of the ICD-11 classification of impulse control disorders and behavioral addictions: An international field study. Journal Of Behavioral Addictions 2024, 13: 276-292. PMID: 38217688, PMCID: PMC10988394, DOI: 10.1556/2006.2023.00083.Peer-Reviewed Original ResearchCompulsive sexual behavior disorderIntermittent explosive disorderImpulse control disordersMental health professionalsICD-10 guidelinesICD-11Control disordersICD-10Behavioral addictionsReward behaviorGaming disorderDisorders due to addictive behaviorsICD-11 chapterSexual behavior disorderICD-11 classificationVignette-based methodologyExplosive disorderAddictive behaviorsBehavioral disordersDiagnostic requirementsNeurodevelopmental disordersHealth professionalsDisordersDiagnostic guidelinesAddiction
2023
Connectome-based prediction of craving in gambling disorder and cocaine use disorder
Antons S, Yip S, Lacadie C, Dadashkarimi J, Scheinost D, Brand M, Potenza M. Connectome-based prediction of craving in gambling disorder and cocaine use disorder. Dialogues In Clinical Neuroscience 2023, 25: 33-42. PMID: 37190759, PMCID: PMC10190201, DOI: 10.1080/19585969.2023.2208586.Peer-Reviewed Original ResearchConceptsCocaine use disorderGambling disorderBehavioral addictionsCue-reactivity taskComponents of memoryGeneral neural mechanismCommon neural networkFunctional magnetic resonanceMedial frontal regionsDefault mode networkFeatures of addictionAutobiographical memoryValence ratingsMeta-analytic dataPrefrontal regionsNeural mechanismsPrefrontal cortexFronto-parietalFrontal regionsMotor imageryMotor/Diverse sampleLimbic networkNeural connectivityCravingFeatures Linked to Treatment Outcomes in Behavioral Addictions and Related Disorders
Mestre-Bach G, Potenza M. Features Linked to Treatment Outcomes in Behavioral Addictions and Related Disorders. International Journal Of Environmental Research And Public Health 2023, 20: 2873. PMID: 36833569, PMCID: PMC9957199, DOI: 10.3390/ijerph20042873.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPotential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions
Mestre-Bach G, Potenza M. Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions. Nutrients 2023, 15: 827. PMID: 36839185, PMCID: PMC9962023, DOI: 10.3390/nu15040827.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInternet gaming disorderGambling disorderVentral striatumBehavioral addictionsBinge Eating DisorderReward processingEating DisordersGaming disorderReward systemTreatment implicationsBrain regionsBrain changesTreatment-related changesAddictionDisordersBingePotential biological markersPossible biomarkersBiological markersMore evidenceSpecific roleProcessingInterventionImplicationsCircuitry
2022
Obsessive-compulsive, harm-avoidance and persistence tendencies in patients with gambling, gaming, compulsive sexual behavior and compulsive buying-shopping disorders/concerns
Mestre-Bach G, Granero R, Fernández-Aranda F, Potenza M, Jiménez-Murcia S. Obsessive-compulsive, harm-avoidance and persistence tendencies in patients with gambling, gaming, compulsive sexual behavior and compulsive buying-shopping disorders/concerns. Addictive Behaviors 2022, 139: 107591. PMID: 36587418, DOI: 10.1016/j.addbeh.2022.107591.Peer-Reviewed Original ResearchConceptsObsessive-compulsive featuresTreatment-seeking patientsObsessive-compulsive subscaleBehavioral addictionsDifferent behavioural addictionsHarm avoidanceDifferent addictionsSymptom ChecklistObsessive-compulsive measuresLower scoresBuying-shopping disorderInternet gaming disorderCompulsive sexual behavior disorderCompulsive sexual behaviorSexual behavior disorderCharacter Inventory-RevisedGambling disorderGaming disorderCharacter InventoryClinical populationsInventory-RevisedPersonality profilesBehavior disorderHigher scoresEmpirical groupA Preregistered, Systematic Review Considering Mindfulness-Based Interventions and Neurofeedback for Targeting Affective and Cognitive Processes in Behavioral Addictions
Brandtner A, Antons S, King D, Potenza M, Tang Y, Blycker G, Brand M, Liebherr M. A Preregistered, Systematic Review Considering Mindfulness-Based Interventions and Neurofeedback for Targeting Affective and Cognitive Processes in Behavioral Addictions. Clinical Psychology Science And Practice 2022, 29: 379-392. DOI: 10.1037/cps0000075.Peer-Reviewed Original ResearchMindfulness-based interventionsCognitive biasesInhibitory controlAddictive behaviorsBehavioral addictionsMindfulness-based cognitive therapyCognitive behavioral therapyEmpirical intervention studiesMindfulness-based techniquesMental distressCognitive processesNeurofeedback techniquesCognitive therapyMindfulness interventionBehavioral therapyTherapeutic changePromising interventionNeurofeedbackCore processesResearch evidenceDistressBiasesAddictionIntervention studiesInterventionThe Potential of N-acetyl Cysteine in Behavioral Addictions and Related Compulsive and Impulsive Behaviors and Disorders: a Scoping Review
Greenberg N, Farhadi F, Kazer B, Potenza M, Angarita G. The Potential of N-acetyl Cysteine in Behavioral Addictions and Related Compulsive and Impulsive Behaviors and Disorders: a Scoping Review. Current Addiction Reports 2022, 9: 660-670. PMID: 38362235, PMCID: PMC10868722, DOI: 10.1007/s40429-022-00446-3.Peer-Reviewed Original ResearchN-acetylcysteineSelf-injurious behaviorEffectiveness of NACEfficacy of NACSmall open-label trialsUse of NACCompulsive sexual behaviorOpen-label trialRepetitive self-injurious behaviorSexual behaviorCompulsive behaviorsGambling disorderGlutamate dysregulationBehavioral addictionsCase reportClinical trialsPreclinical studiesGlutamate homeostasisAcetyl cysteineDisordersMore studiesScoping ReviewCompulsive featuresAddictionImpulsive behavior
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