2025
Association between joint attention and autism traits in young adults: A gaze-contingent eye-tracking study
Yoon C, Meadan H, Xia Y, Shic F. Association between joint attention and autism traits in young adults: A gaze-contingent eye-tracking study. Research In Autism 2025, 125: 202622. DOI: 10.1016/j.reia.2025.202622.Peer-Reviewed Original ResearchAssociated with autism traitsAutism traitsJoint attentionEye-tracking taskInteractive eye-trackingTraits in adulthoodEye-tracking methodologyYoung adultsDifficulties associated with autismEye-tracking studyHuman communication partnerEye-tracking researchAttentional demandsAutistic childrenCommunication partnersAutismEye trackingAttention variationDevelopmental significanceAdulthoodTraitsAdultsLinear mixed modelsAttentionAdolescentsSocial Support and Social Strain Sources as Predictors of Multimorbidity Changes in Middle-Aged and Older Adults.
Newsom J, Saucedo J, Kroeck M, O'Neill A, Allore H, Nagel C, Botoseneanu A, Trubits E, Dorr D, Quiñones A. Social Support and Social Strain Sources as Predictors of Multimorbidity Changes in Middle-Aged and Older Adults. Journal Of Aging And Health 2025, 8982643251351090. PMID: 40557788, DOI: 10.1177/08982643251351090.Peer-Reviewed Original ResearchSocial supportOlder adultsAccumulation of chronic conditionsHealth and Retirement StudyPromote healthy agingSources of supportTrajectory classesPsychosocial interventionsRetirement StudyChronic conditionsPredictors of trajectory classesMiddle-agedSocial strainHealthy agingDiscussionThe importanceAdultsObjectivesThis studyChildrenSupportAgeOlderSocialPredictorsDiscussionTheHealthEffects of oral nicotine pouches on cigarette smoking behaviour and tobacco harm exposure: a randomised pilot trial in adults
Fucito L, Baldassarri S, Wu R, Gueorguieva R, Morean M, Herbst R, Krishnan-Sarin S, O’Malley S. Effects of oral nicotine pouches on cigarette smoking behaviour and tobacco harm exposure: a randomised pilot trial in adults. Tobacco Control 2025, tc-2024-059094. PMID: 40550628, DOI: 10.1136/tc-2024-059094.Peer-Reviewed Original ResearchSmoking abstinenceOral nicotine pouchesSmoking behaviorNicotine pouchesRandomised pilot trialPoint prevalence smoking abstinenceComplete smoking abstinenceOutpatient research clinicCigarette smoking behaviorPreliminary supportTobacco-specific carcinogenNon-significantNicotineResearch clinicOpen-labelSmoking cessationAbstinenceCigarette substituteUrinary levelsWeek 4Nicotine strengthSmoking cigarettesParticipantsCompare groupsAdults1926-LB: A Qualitative Descriptive Study of Motivation States in Physical Activity among Middle-Aged Adults with Type 1 Diabetes
ASH G, HERNANDEZ E, (VERA) WANG X, GRIGGS S. 1926-LB: A Qualitative Descriptive Study of Motivation States in Physical Activity among Middle-Aged Adults with Type 1 Diabetes. Diabetes 2025, 74 DOI: 10.2337/db25-1926-lb.Peer-Reviewed Original ResearchPhysical activityInfluence physical activity engagementPhysical activity engagementQualitative descriptive studyType 1 diabetesMiddle-aged adultsSemi-structured interviewsSedentary timeExercise interventionQualitative descriptive approachMuscle fatigueInductive codingDescriptive studyNeuromuscular taskActive engagementDescriptive approachMotivational stateQuantitative surveyPsychological stateAdultsWAnTInterventionParticipantsPsychological considerationsT1DThe Endocannabinoid System and Postnatal Neurodevelopment
Sisk L, Meyer H, Martinez-Garcia A, Gee D. The Endocannabinoid System and Postnatal Neurodevelopment. 2025, 83-112. DOI: 10.1007/978-3-031-87990-6_5.Peer-Reviewed Original ResearchStress-related disordersECB systemResilience to stress-related disordersMaturation of neuronal populationsResponse to stressECB signalingECB levelsFunctional connectivityHuman literaturePostnatal neurodevelopmentNeuronal populationsECBDisordersHuman studiesInfluence riskNeurodevelopmentEndocannabinoidAnxietyEndocrine systemRiskSignaling systemPotential riskYouthAdultsTitration and discontinuation of semaglutide for weight management in commercially insured US adults
Xu Y, Carrero J, Chang A, Inker L, Zhang D, Mukhopadhyay A, Blecker S, Horwitz L, Grams M, Shin J. Titration and discontinuation of semaglutide for weight management in commercially insured US adults. Obesity 2025, 33: 1243-1248. PMID: 40464214, DOI: 10.1002/oby.24315.Peer-Reviewed Original ResearchConceptsDose escalation scheduleHigher discontinuation rateDiscontinuation ratesWeight managementMultivariate Cox regressionUS adultsAssociated with discontinuationCommercially insured adultsEarly discontinuationAssociated with low household incomeCox regressionSemaglutideLowest quintileHighest quintileDelivery of evidence-based careLower household incomeMonthsEvidence-based careCopayment amountQuintileAdultsReduce financial barriersDiscontinuationEducation levelIdentified factorsJoint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States.
Chu L, Wang R, Gross C, Wei J, Lu Y, Krumholz H, Ma X, Chen K. Joint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States. Circulation 2025 PMID: 40458867, DOI: 10.1161/circulationaha.124.073614.Peer-Reviewed Original ResearchIncident acute myocardial infarctionAcute myocardial infarctionIncreased oddsRisk of acute myocardial infarctionHigher risk of acute myocardial infarctionProbability of acute myocardial infarctionOccurrence of acute myocardial infarctionRandom-effects meta-analysisCase-crossover studyMultivariate random-effects meta-analysisExposure to ozoneRegion-specific estimatesMyocardial infarctionStatistical interaction termsAmbient ozone pollutionPrevention strategiesUnited StatesJoint exposureMeta-analysisAdult ageYoung adultsHigh riskAdultsOddsInteraction termsTrends and Key Factors Associated With Racial and Ethnic Differences in Life’s Essential 8 Scores
Yang H, Huang C, Sawano M, Herrin J, Faridi K, Li Z, Spatz E, Krumholz H, Lu Y. Trends and Key Factors Associated With Racial and Ethnic Differences in Life’s Essential 8 Scores. JAMA Network Open 2025, 8: e2516663. PMID: 40531529, PMCID: PMC12177675, DOI: 10.1001/jamanetworkopen.2025.16663.Peer-Reviewed Original ResearchConceptsLife's Essential 8 scoreLife's Essential 8Cross-sectional studyWhite differencesEthnic differencesNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveySleep health scoreNutrition Examination SurveyGroup-specific interventionsPrimary positive factorPhysical activityExamination SurveyHealth scoresBlack adultsWhite adultsMain OutcomesAsian adultsOverall scoreEvaluate trendsNicotine exposureEssential 8Blood lipidsAdultsEthnic groupsCancer care for adolescents and young adults under the age of 50 in Saudi Arabia: policy review, research gaps, and future directions
Alessy S, Alghamdi M, Al-Bawardy B, Alghamdi S, Al-Hamoudi W, Alomaim W, Abaalkhail F, Alqarni A, Alsharm A, Alqurashi Y, Bokhary M, Alqahtani S. Cancer care for adolescents and young adults under the age of 50 in Saudi Arabia: policy review, research gaps, and future directions. EClinicalMedicine 2025, 103188. DOI: 10.1016/j.eclinm.2025.103188.Peer-Reviewed Original ResearchCancer incidence ratesPatient-centred careIncreasing cancer incidence ratesPublic health challengeYoung adultsSurvivorship carePsychological well-beingCancer carePsychosocial needsCare providersCancer ratesYears of ageHealthcare institutionsHealth challengesIncidence rateAYACareSaudi ArabiaUnified treatment protocolRisk factorsPolicy developmentPolicy reviewResearch initiativesTargeted researchAdultsSynthetic cannabinoid use and the acquired preparedness model
Pia T, Weinberger A. Synthetic cannabinoid use and the acquired preparedness model. American Journal On Addictions 2025 PMID: 40392442, DOI: 10.1111/ajad.70049.Peer-Reviewed Original ResearchAcquired preparedness modelFacets of impulsivitySC useSynthetic cannabinoidsAssociated with greater frequencySynthetic cannabinoid useSensation seekingAdult samplesCannabinoid useMediation analysisPreparedness modelU.S. sampleGreater frequencyPsychological effectsImpulseGeneral United StatesU.S. adultsPotential motivationsOnline surveyCross-sectional studyAdultsMotivationAddictionCannabinoidAnxiety0949 Validation of Self-Reported Sleep Duration Using the Method of Triads Among Older Adults with Sleep Disturbances
Xu E, Cho G, Chen A, Talarcyzk J, Dolye M, Miner B. 0949 Validation of Self-Reported Sleep Duration Using the Method of Triads Among Older Adults with Sleep Disturbances. Sleep 2025, 48: a412-a412. DOI: 10.1093/sleep/zsaf090.0949.Peer-Reviewed Original ResearchSelf-reported measures of sleep durationValidity coefficientsSleep diaryDays of sleep diariesSleep disturbanceSelf-report measuresComparison of self-reportedSymptoms of insomniaOlder adultsAssociation of SDMeasures of sleep durationSleep durationTriangular comparisonSelf-reportPath analysisEEG headbandActigraphyEvaluate SDSleepEstimate validity coefficientsWrist actigraphySD measuresNights of wrist actigraphyObjective measuresAdultsAge-invariant benefits of spatiotemporal predictions amidst distraction during dynamic visual search
Shalev N, Boettcher S, Nobre A. Age-invariant benefits of spatiotemporal predictions amidst distraction during dynamic visual search. Scientific Reports 2025, 15: 17078. PMID: 40379870, PMCID: PMC12084335, DOI: 10.1038/s41598-025-01796-4.Peer-Reviewed Original ResearchConceptsSensitivity to distractionGoal-driven attentionGuidance of attentionVisual search taskOlder adultsAge-related differencesEffects of predictabilityDynamic visual searchAttentional controlHigh distractionAttentional guidanceGoal-directedVisual searchSearch taskDistractorsStudy attentionDistractionPoor performanceSpatiotemporal regularityDistracting elementsAdultsAttentionDeficitsSedation for moderate‐to‐severe traumatic brain injury in adults
Williamson D, Dryden L, Cheng W, Hutton B, Skidmore B, Mehta S, Golan E, Turgeon A, Adhikari N, Rose L, Burry L. Sedation for moderate‐to‐severe traumatic brain injury in adults. Cochrane Database Of Systematic Reviews 2025, 2025: cd012639. PMID: 40326601, PMCID: PMC12053465, DOI: 10.1002/14651858.cd012639.pub2.Peer-Reviewed Original ResearchAssociation Between Skilled Rehabilitation in Hospital and Days Alive and at Home Following Critical Illness in Older Adults
Kim S, Murphy T, O'Leary J, Leo-Summers L, Zang E, Falvey J, Gill T, Krumholz H, Ferrante L, Jain S. Association Between Skilled Rehabilitation in Hospital and Days Alive and at Home Following Critical Illness in Older Adults. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a1173-a1173. DOI: 10.1164/ajrccm.2025.211.abstracts.a1173.Peer-Reviewed Original Research7. Preliminary Evidence of Synaptic Deficits in Older Adults With Mood Disorders and Associations With Symptom Severity and Suicide Risk
Asch R, Moisieienko K, Cool R, Weed M, Steffens D, Carson R, Pietrzak R, Esterlis I. 7. Preliminary Evidence of Synaptic Deficits in Older Adults With Mood Disorders and Associations With Symptom Severity and Suicide Risk. Biological Psychiatry 2025, 97: s76-s77. DOI: 10.1016/j.biopsych.2025.02.197.Peer-Reviewed Original ResearchHealthy ageing in older adults with cardiovascular disease
Schmanske N, Ngo J, Kalra K, Nanna M, Damluji A. Healthy ageing in older adults with cardiovascular disease. European Heart Journal 2025, ehaf231. PMID: 40296653, DOI: 10.1093/eurheartj/ehaf231.Peer-Reviewed Original ResearchHealthy agingOlder adultsGeriatric syndromesCardiovascular diseasePrevalence of chronic diseasesPopulation of older adultsDevelopment of geriatric syndromesImpact of geriatric syndromesPromote healthy agingAccelerated biological agingBiological ageUS populationChronic diseasesPotential interventionsLife expectancyPublic healthOlder patientsEuropean populationsMedical technologyAgeAdultsPopulationDiseaseSyndromeSocioeconomic progressThe perils of pickleball: A two decade analysis of upper and lower extremity injuries from America’s fastest growing sport
Boroumand S, Park N, Katsnelson B, Qian E, Norman M, Joo P, Diatta F, Noel O, Moran J, Jimenez A. The perils of pickleball: A two decade analysis of upper and lower extremity injuries from America’s fastest growing sport. Journal Of Sports Sciences 2025, 43: 1378-1385. PMID: 40254855, DOI: 10.1080/02640414.2025.2496089.Peer-Reviewed Original ResearchConceptsLower extremity injuriesExtremity injuriesUS emergency departmentsAge groupsTwo-proportion z-testInjury trendsGeriatric age groupPickleball injuriesEmergency departmentUpper/lower extremitiesBonferroni correctionPediatric patientsEpidemiological analysisClinical variablesZ-testPatientsAdultsInjuryPickleballExtremitiesX-Linked Hypophosphatemia Management in Adults: An International Working Group Clinical Practice Guideline
Khan A, Ali D, Appelman-Dijkstra N, Carpenter T, Chaussain C, Imel E, de Beur S, Florenzano P, Abu Alrob H, Aldabagh R, Alexander R, Alsarraf F, Beck-Nielsen S, Biosse-Duplan M, Cohen-Solal M, Crowley R, Dandurand K, Filler G, Friedlander L, Fukumoto S, Gagnon C, Goodyer P, Grasemann C, Grimbly C, Hussein S, Javaid M, Khan S, Khan A, Lehman A, Lems W, Lewiecki E, McDonnell C, Mirza R, Morgante E, Morrison A, Portale A, Rhee Y, Rush E, Siggelkow H, Tetradis S, Tosi L, Ward L, Guyatt G, Brandi M. X-Linked Hypophosphatemia Management in Adults: An International Working Group Clinical Practice Guideline. The Journal Of Clinical Endocrinology & Metabolism 2025, dgaf170. PMID: 40243526, DOI: 10.1210/clinem/dgaf170.Peer-Reviewed Original ResearchInternational Working GroupSystematic reviewX-linked hypophosphatemiaClinical practice guidelinesPatient-important outcomesCertainty of evidenceConventional therapyNo therapyDiagnosis of XLHPatient partnersPatient societiesAbsence of fractureMultidisciplinary teamPractice guidelinesInsufficient evidenceGlobal guidelinesGRADE methodologyTreated with conventional therapyNarrative reviewRenal phosphate wastingSymptomatic adultsEffective medical therapyAdultsWorking GroupPathogenic variantsGlobal Profiles of Positive Youth Development: A Person-Oriented Analysis among Emerging Adults Living in 21 Countries
Buenconsejo J, Ferrer-Wreder L, Dimitrova R, Pavlova I, Bosnar K, Bartoluci S, Katović D, Prot F, Sultana M, Islam M, Michałek-Kwiecień J, Skrzypińska K, Kazmierczak M, Lewandowska-Walter A, Borchet J, Buzea C, Stefenel D, Page D, Luden M, Jovanović V, Kittieteerasack P, Stanciu A, Friehs M, Rivera R, Aruta J, Bodnar I, Petrytsa P, Andres A, Wendt G, Thome L, Yunes M, Giordani R, Musso P, Cassibba R, Silletti F, Miconi D, Karakulak A, Yıldırım E, Martín-Carbonell M, Palacio L, Gaete J, Landabur R, Chen B, Gan Y, Lin D, Abdul Kadir N, Krauss S, Ayub N, Saiful M, Malik S, Yu Y, Gantulga U, Dagvadorj A, Ganbaatar N, Altansukh S. Global Profiles of Positive Youth Development: A Person-Oriented Analysis among Emerging Adults Living in 21 Countries. Journal Of Youth And Adolescence 2025, 1-26. PMID: 40205131, DOI: 10.1007/s10964-025-02174-z.Peer-Reviewed Original ResearchCollectivistic countriesAssociated with specific profilesPerson-oriented analytical approachLess-educated femalesSelf-efficacyPerson-oriented analysesSocio-emotional profilesPositive youth developmentModel of positive youth developmentDiverse socio-cultural contextsLatent profile analysisSocio-cultural contextEducational attainmentYouth developmentMaladaptive outcomesSelf-efficacy profilesSocio-emotionalCountriesPositive adaptationParticipant ageDevelopmental settingsProfile analysisCOVID-19 pandemicGlobal researchAdultsRULER: A Theory-Driven, Systemic Approach to Social, Emotional, and Academic Learning
Brackett M, Bailey C, Hoffmann J, Simmons D. RULER: A Theory-Driven, Systemic Approach to Social, Emotional, and Academic Learning. 2025, 20-38. DOI: 10.4324/9781003054573-3.Peer-Reviewed Original Research
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