2025
Cognitive bias modification for individuals with opioid use disorder and chronic pain did not predict changes in clinical outcomes.
Wolkowicz N, Pittman B, Schrader S, Wesolowicz D, Sofuoglu M, Heapy A, MacLean R. Cognitive bias modification for individuals with opioid use disorder and chronic pain did not predict changes in clinical outcomes. Journal Of Studies On Alcohol And Drugs 2025 PMID: 40536409, DOI: 10.15288/jsad.25-00057.Peer-Reviewed Original ResearchCognitive bias modificationAttentional biasOpioid cravingBias modificationCBM effectsSubstance use disordersPain severityChronic painClinical outcomesAddiction severityOpioid use disorderUse disorderNaturalistic settingsNeutral-cueOpioid withdrawalPain cuesCravingDiverse sampleSalient outcomesSubstance typePreliminary effectivenessPrimary clinical outcomePain catastrophizingModerate painPain intensityIdentification and external validation of a problem cannabis risk network
Lichenstein S, Kiluk B, Potenza M, Garavan H, Chaarani B, Banaschewski T, Bokde A, Desrivières S, Flor H, Grigis A, Gowland P, Heinz A, Brühl R, Martinot J, Paillère Martinot M, Artiges E, Nees F, Orfanos D, Poustka L, Hohmann S, Holz N, Baeuchl C, Smolka M, Vaidya N, Walter H, Whelan R, Schumann G, Pearlson G, Yip S. Identification and external validation of a problem cannabis risk network. Biological Psychiatry 2025 PMID: 39909136, DOI: 10.1016/j.biopsych.2025.01.022.Peer-Reviewed Original ResearchAlcohol use outcomesCannabis useNeural mechanismsSample of treatment-seeking adultsNeural mechanisms of riskTreatment-seeking adultsCannabis use disorderNon-clinical sampleMechanisms of riskFunctional connectivity dataSample of adolescentsTreatment outcomesAssociated with harmful outcomesPoor treatment outcomesAddiction severityUse disorderEmerging adulthoodWhole-brainCannabisCollege studentsBrain developmentConnectivity dataIdentified networksTreatment approachesAdults
2024
Genes associated with cortical thickness alterations in behavioral addiction
Xie H, Wang Y, Zhu F, Zhang F, Wu B, Zhao Z, Gan R, Gong Q, Jia Z. Genes associated with cortical thickness alterations in behavioral addiction. Cerebral Cortex 2024, 34: bhae298. PMID: 39051658, DOI: 10.1093/cercor/bhae298.Peer-Reviewed Original ResearchConceptsBehavioral addictionsCortical thicknessBehavioral regulationPostcentral gyrusCompulsive reward-seeking behaviorReward-seeking behaviorDorsolateral prefrontal cortexDopamine D2 receptorsAllen Human Brain AtlasOrbital-frontal cortexCortical thickness alterationsHuman Brain AtlasAddiction phenotypesAddiction severityPrefrontal cortexD2 receptorsDopamine metabolismBrain areasNeurogenetic mechanismsAddictionThickness alterationsPrecuneusGyrusDopamineResponse to stimuliEfficacy and Neural Mechanisms of Mindfulness Meditation Among Adults With Internet Gaming Disorder
Ni H, Wang H, Ma X, Li S, Liu C, Song X, Potenza M, Dong G. Efficacy and Neural Mechanisms of Mindfulness Meditation Among Adults With Internet Gaming Disorder. JAMA Network Open 2024, 7: e2416684. PMID: 38888924, PMCID: PMC11185988, DOI: 10.1001/jamanetworkopen.2024.16684.Peer-Reviewed Original ResearchConceptsInternet gaming disorderDSM-5-TRProgressive muscle relaxationMindfulness meditationProgressive muscle relaxation groupNeural mechanismsGaming cravingsAddiction severityDecreased cravingFunctional connectivityAssociated with decreased brain activitySeverity of internet gaming disorderInternet gaming disorder severityTreating Internet Gaming DisorderBlood oxygen level-dependent signalCue-craving taskMedial frontal gyrusPotential neural mechanismsProgressive muscle relaxation trainingBilateral lentiform nucleusFrontal gyrusIncreased mindfulnessBrain measuresGaming disorderBrain regionsPavlovian-to-instrumental transfer and outcome-devaluation effects in individuals with gaming experience
Xu L, Zhang J, Geng X, Song K, Zeng P, Potenza M, Schad D, Zhang J. Pavlovian-to-instrumental transfer and outcome-devaluation effects in individuals with gaming experience. Computers In Human Behavior 2024, 155: 108188. DOI: 10.1016/j.chb.2024.108188.Peer-Reviewed Original ResearchRecreational game useInternet gaming disorderInternet gaming disorder groupHabitual controlInstrumental behaviorPavlovian-to-instrumental transferDevelopment of internet gaming disorderGaming-related cuesSubstance use disordersForty-five adultsTransfer effectsGaming behaviorDevaluation sensitivityPavlovian cuesDevaluation procedureMonetary cuesPIT taskAddiction severityAddiction developmentAddictive behaviorsLearned associationsGaming disorderNo-goOutcome valuesPIT effectWanting-liking dissociation and altered dopaminergic functioning: Similarities between internet gaming disorder and tobacco use disorder
Ma X, Wang M, Zhou W, Zhang Z, Ni H, Jiang A, Zheng Y, Du X, Potenza M, Dong G. Wanting-liking dissociation and altered dopaminergic functioning: Similarities between internet gaming disorder and tobacco use disorder. Journal Of Behavioral Addictions 2024, 13: 596-609. PMID: 38635338, PMCID: PMC11220823, DOI: 10.1556/2006.2024.00011.Peer-Reviewed Original ResearchInternet gaming disorderTobacco use disorderIGD participantsGaming disorderCue-craving taskImplicit Association TestBrain-behavior mechanismsHealthy control participantsImplicit association test resultsFunctional MRI dataNeuromelanin-sensitive MRIIncentive sensitizationAddiction severityDopaminergic involvementDSM-5Dopaminergic functionDopaminergic systemPotential dissociationUse disorderControl participantsBrain featuresHedonic responsesAssociation TestGaming motivesNeural features
2022
Neuromodulation treatments of problematic use of the Internet
Xu L, Geng X, Zhang J, Guo X, Potenza M, Zhang J. Neuromodulation treatments of problematic use of the Internet. Current Opinion In Behavioral Sciences 2022, 48: 101215. DOI: 10.1016/j.cobeha.2022.101215.Peer-Reviewed Original ResearchProblematic useBrain circuitsTranscranial direct current stimulationDorsolateral prefrontal cortexDirect current stimulationRepetitive transcranial magnetic stimulationExecutive controlNegative emotionsStimulus contextTranscranial magnetic stimulationAddictive behaviorsPrefrontal cortexCurrent stimulationAddiction severityBrain regionsMagnetic stimulationNeuromodulation treatmentsInvasive stimulationEmotionsCausal relationshipCravingFunctioningRigorous experimentsAddictionCortexChildhood Adversity, Addiction Severity, and Comorbidity Among Patients Receiving Opioid Use Disorder Treatment
Carr M, Ellis J, Saules K, Ledgerwood D. Childhood Adversity, Addiction Severity, and Comorbidity Among Patients Receiving Opioid Use Disorder Treatment. The Journal Of Nervous And Mental Disease 2022, 211: 150-156. PMID: 36112518, DOI: 10.1097/nmd.0000000000001581.Peer-Reviewed Original ResearchConceptsOpioid use disorder treatmentUse disorder treatmentClinical severityChildhood adversityDisorder treatmentOpioid agonist treatmentChildhood adversity exposureGreater childhood adversityOUD treatmentAgonist treatmentTreatment strategiesEmotion dysregulationEmotion regulationCurrent psychopathologyAddiction severityPatientsAdversity exposureSymptom typeSeverityWomenStrongest predictorTreatmentHigh rateDysregulationGreater exposureMedication for opioid use disorder in the Arab World: A systematic review
Alawa J, Muhammad M, Kazemitabar M, Bromberg DJ, Garcia D, Khoshnood K, Ghandour L. Medication for opioid use disorder in the Arab World: A systematic review. International Journal Of Drug Policy 2022, 102: 103617. PMID: 35182841, PMCID: PMC9851143, DOI: 10.1016/j.drugpo.2022.103617.Peer-Reviewed Original ResearchConceptsOpioid use disorderUse disordersSystematic reviewGlobal public health concernOpioid agonist therapyImplementation science studyStandard of careCASP appraisal toolHealth system aspectsPublic health concernPositive health outcomesAgonist therapyOUD patientsPatients' qualityPatient satisfactionPatient levelInclusion criteriaPatient's perspectiveMOUDHealth outcomesFinal reviewMedicationsHealth concernHealth practitionersAddiction severity
2018
Hypothalamic response to cocaine cues and cocaine addiction severity
Zhang S, Zhornitsky S, Angarita GA, Li C. Hypothalamic response to cocaine cues and cocaine addiction severity. Addiction Biology 2018, 25: e12682. PMID: 30295396, PMCID: PMC6453736, DOI: 10.1111/adb.12682.Peer-Reviewed Original ResearchConceptsCocaine Craving QuestionnaireCocaine Selective Severity AssessmentFunctional magnetic resonance imagingCocaine-dependent individualsAddiction severityOrbitofrontal cortexHypothalamic responseVentral striatumCocaine addictionCocaine cuesAngular gyrusBilateral orbitofrontal cortexBilateral visual cortexCue-induced cravingMagnetic resonance imagingMiddle frontal gyrusClinical featuresNeutral cuesDopaminergic circuitsHypothalamusVisual cortexResonance imagingDopaminergic midbrainFrontal gyrusAg responseStress and Addiction
Sinha R. Stress and Addiction. 2018, 299-311. DOI: 10.4324/9781315689197-25.Peer-Reviewed Original ResearchExecutive control functionsNegative emotional statesChronic stressEarly life stressCortical brain regionsEmotional statesAddiction vulnerabilityStressful situationsMesolimbic dopamine pathwayLife stressAddiction severityBrain regionsType of adaptationDrug useDopamine pathwayAlters activityRelapse riskEmotionsIndividualsDistressControl functionsAddictionAbuseBehaviorStress
2017
Mothering From the Inside Out: Results of a second randomized clinical trial testing a mentalization-based intervention for mothers in addiction treatment
Suchman NE, DeCoste CL, McMahon TJ, Dalton R, Mayes LC, Borelli J. Mothering From the Inside Out: Results of a second randomized clinical trial testing a mentalization-based intervention for mothers in addiction treatment. Development And Psychopathology 2017, 29: 617-636. PMID: 28401850, PMCID: PMC5407293, DOI: 10.1017/s0954579417000220.Peer-Reviewed Original ResearchConceptsSecond randomized clinical trialRandomized clinical trialsMother-child interaction qualityClinical trialsYoung childrenMaternal reflective functioningAddiction treatmentMentalization-based interventionsHistory of alcoholActive control comparisonsMonths of agePE mothersChronic substance usePE cohortParent educationSubstance misuseProtective factorsAddiction severityIndividual therapySubstance useReflective functioningPsychological deficitsDrug addictionMothersMother-child interaction
2016
Pretreatment Drug use Characteristics and Experiences among Patients in a Voluntary Substance Abuse Treatment Center in Malaysia: A Mixed-Methods Approach
Krishnan A, Brown SE, Ghani MA, Khan F, Kamarulzaman A, Altice FL. Pretreatment Drug use Characteristics and Experiences among Patients in a Voluntary Substance Abuse Treatment Center in Malaysia: A Mixed-Methods Approach. Substance Abuse 2016, 37: 542-549. PMID: 26914230, PMCID: PMC5551393, DOI: 10.1080/08897077.2016.1146648.Peer-Reviewed Original ResearchConceptsCompulsory drug detention centersDrug use characteristicsDrug useAmphetamine useTreatment centersDrug usersVoluntary drug treatment centresIllicit amphetamine useInjection drug useDrug treatment centersSubstance abuse treatment centersDrug use patternsDrug use profilesHigh-risk behaviorsSignificant public healthDrug initiationCare centerHigh prevalencePolysubstance useNortheast MalaysiaAddiction severityPatientsBehavioral interventionsAddiction treatmentConvenience samplePre‐incarceration police harassment, drug addiction and HIV risk behaviours among prisoners in Kyrgyzstan and Azerbaijan: results from a nationally representative cross‐sectional study
Polonsky M, Azbel L, Wegman MP, Izenberg JM, Bachireddy C, Wickersham JA, Dvoriak S, Altice FL. Pre‐incarceration police harassment, drug addiction and HIV risk behaviours among prisoners in Kyrgyzstan and Azerbaijan: results from a nationally representative cross‐sectional study. Journal Of The International AIDS Society 2016, 19: 20880. PMID: 27435715, PMCID: PMC4951538, DOI: 10.7448/ias.19.4.20880.Peer-Reviewed Original ResearchConceptsRepresentative cross-sectional studyHIV risk behaviorsCross-sectional studyHIV riskAddiction severityRisk behaviorsHIV risk-taking behaviorsPrison drug injectionDrug addiction severityHealth assessment surveyHIV transmissionPotential confoundersDrug injectionHIV epidemicDrug usersHigher addiction severityDrug useBivariate testingThird of prisonersDrug addictionSeverityPWIDEpidemic responseRiskStrongest correlateAttitudes Toward Addiction, Methadone Treatment, and Recovery Among HIV-Infected Ukrainian Prisoners Who Inject Drugs: Incarceration Effects and Exploration of Mediators
Polonsky M, Rozanova J, Azbel L, Bachireddy C, Izenberg J, Kiriazova T, Dvoryak S, Altice FL. Attitudes Toward Addiction, Methadone Treatment, and Recovery Among HIV-Infected Ukrainian Prisoners Who Inject Drugs: Incarceration Effects and Exploration of Mediators. AIDS And Behavior 2016, 20: 2950-2960. PMID: 27011378, PMCID: PMC5035551, DOI: 10.1007/s10461-016-1375-0.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyGroup 1Drug useGroup 2 participantsDrug addiction severityAwareness of addictionMaintenance therapyMethadone treatmentExploration of mediatorsHIV stigmaGroup 2MMT treatmentAddiction severityGroup comparisonsDrug addictionHIVHigh rateAddictionHigher optimismDrugsTreatmentParticipantsMethadoneGroupPaper’s key findings
2013
Patterns of Homelessness and Implications for HIV Health After Release from Jail
Zelenev A, Marcus R, Kopelev A, Cruzado-Quinones J, Spaulding A, Desabrais M, Lincoln T, Altice FL. Patterns of Homelessness and Implications for HIV Health After Release from Jail. AIDS And Behavior 2013, 17: 181-194. PMID: 23657757, PMCID: PMC4625835, DOI: 10.1007/s10461-013-0472-6.Peer-Reviewed Original ResearchConceptsHIV treatment outcomesTreatment outcomesNon-homeless patientsDrug addiction severityUse of alcoholVirological suppressionHIV healthHealth behaviorsJail detaineesMental illnessSubstance abuseAddiction severityMental healthCorrelates of homelessnessIllicit drugsStable housingHousing statusEffects of housingOutcomesHealthDifferent patternsHIVLongitudinal dataPatientsIllness
2011
Medication Persistence of HIV-infected Drug Users on Directly Administered Antiretroviral Therapy
Ing EC, Bae JW, Maru DS, Altice FL. Medication Persistence of HIV-infected Drug Users on Directly Administered Antiretroviral Therapy. AIDS And Behavior 2011, 17: 113-121. PMID: 22105340, DOI: 10.1007/s10461-011-0082-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveBehavior, AddictiveCD4 Lymphocyte CountConnecticutDirectly Observed TherapyDrug UsersFemaleHIV InfectionsHumansInterviews as TopicKaplan-Meier EstimateMaleMedication AdherenceProportional Hazards ModelsRandomized Controlled Trials as TopicRNA, ViralSeverity of Illness IndexSubstance Abuse, IntravenousTreatment OutcomeViral LoadConceptsDrug usersAntiretroviral therapyPatterns of medicationInjection drug useMedication-taking behaviorHigher depressive symptomsVirological outcomesMedication persistenceRegimen changeMore episodesDepressive symptomsHigher addiction severityDrug useSignificant associationConsecutive daysHIVAddiction severityMedicationsMEMS dataTherapyDaysEpisodesParticipantsRegimensDAART
2009
Construct, concurrent and predictive validity of the URICA: Data from two multi-site clinical trials
Field CA, Adinoff B, Harris TR, Ball SA, Carroll KM. Construct, concurrent and predictive validity of the URICA: Data from two multi-site clinical trials. Drug And Alcohol Dependence 2009, 101: 115-123. PMID: 19157723, PMCID: PMC3097110, DOI: 10.1016/j.drugalcdep.2008.12.003.Peer-Reviewed Original ResearchConceptsPredictive validityCommitted actionRhode Island Change AssessmentRole of motivationEffect of motivationBrief motivational interventionMotivational enhancement therapyComposite scoreTreatment outcomesConfirmatory factor analysisAlcohol dependenceDrug Abuse Clinical Trials NetworkClinical trialsMotivational interventionEnhancement therapyMotivational interviewingAlcohol-dependent patientsFactor structureAddiction severityMulti-site clinical trialSubstance useClinical Trials NetworkConstruct validityTreatment retentionURICA
1997
Maternal Attentiveness of Cocaine Abusers During Child—Based Assessments
Ball S, Mayes L, DeTeso J, Schottenfeld R. Maternal Attentiveness of Cocaine Abusers During Child—Based Assessments. American Journal On Addictions 1997, 6: 135-143. PMID: 9134075, DOI: 10.1111/j.1521-0391.1997.tb00562.x.Peer-Reviewed Original ResearchA Five-Factor Model of Personality and Addiction, Psychiatric, and AIDS Risk Severity in Pregnant and Postpartum Cocaine Misusers
Ball S, Schottenfeld R. A Five-Factor Model of Personality and Addiction, Psychiatric, and AIDS Risk Severity in Pregnant and Postpartum Cocaine Misusers. Substance Use & Misuse 1997, 32: 25-41. PMID: 9044535, DOI: 10.3109/10826089709027295.Peer-Reviewed Original ResearchConceptsFive-factor measureZuckerman-Kuhlman Personality QuestionnaireFive-factor modelPsychiatric symptomsOutpatient treatment programBeck Depression InventoryNeuroticism-AnxietyPersonality dimensionsPersonality QuestionnaireAddiction Severity IndexSample of womenAddiction severityDifferent subscalesTreatment programSymptom severityAIDS risk behaviorsPersonalityDepression InventoryCocaine misusersRisk behaviorsPowerful predictor
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