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Zachary Levine, PhD

Assistant Professor of Pathology

Contact Information

Zachary Levine, PhD

Lab Location

  • 266 Whitney Avenue, Rm 320
    New Haven, CT, 06511

Mailing Address

  • Yale University

    266 Whitney Ave., Bass Center, Rm. 320

    New Haven, CT, 06520-8114

    United States



Zachary Levine is currently an Assistant Professor of Pathology at the Yale School of Medicine and the Graduate School at Yale University. His training is in computational biophysics and his interests have recently expanded into solution biophysics techniques in amyloid protein systems. Many of his projects combine atomistic models with solution NMR spectroscopy in order to better understand the physical and thermodynamic determinants of age-related diseases.

In particular, we work to understand protein aggregation diseases from a biophysical perspective. Many of these conditions involve a toxic accumulation of amyloid proteins and plaques over the lifecourse, leading to degenerative dysfunction and death. By combining molecular models of protein folding and aggregation with solution biophysics techniques, we can deduce and modify thermodynamic landscapes that are distinctly pathological in order to mitigate human diseases.

Education & Training

  • PhD
    University of Southern California, Physics (2013)
  • MSc
    University of Southern California, Computer Science (2012)
  • MA
    University of Southern California, Physics (2008)
  • BS
    San Francisco State University, Physics (2006)
  • Postdoctoral Training
    University of California Santa Barbara

Professional Service

Biophysical Society - Intrinsically Disordered Protein SubgroupCo-Chair2019 - 2020

Departments & Organizations