Research & Publications
Zachary Levine is currently an Assistant Professor of Pathology at the Yale School of Medicine and the Graduate School at Yale University. His training is in computational biophysics and his interests have recently expanded into solution biophysics techniques in amyloid protein systems. Many of his projects combine atomistic models with solution NMR spectroscopy in order to better understand the physical and thermodynamic determinants of age-related diseases.
In particular, we work to understand protein aggregation diseases from a biophysical perspective. Many of these conditions involve a toxic accumulation of amyloid proteins and plaques over the lifecourse, leading to degenerative dysfunction and death. By combining molecular models of protein folding and aggregation with solution biophysics techniques, we can deduce and modify thermodynamic landscapes that are distinctly pathological in order to mitigate human diseases.
Education & Training
- PhDUniversity of Southern California, Physics (2013)
- MScUniversity of Southern California, Computer Science (2012)
- MAUniversity of Southern California, Physics (2008)
- BSSan Francisco State University, Physics (2006)
- Postdoctoral TrainingUniversity of California Santa Barbara
|Biophysical Society - Intrinsically Disordered Protein Subgroup||Co-Chair||2019 - 2020|