2018
Modeling elastin-associated vasculopathy with patient induced pluripotent stem cells and tissue engineering
Ellis MW, Luo J, Qyang Y. Modeling elastin-associated vasculopathy with patient induced pluripotent stem cells and tissue engineering. Cellular And Molecular Life Sciences 2018, 76: 893-901. PMID: 30460472, PMCID: PMC6433159, DOI: 10.1007/s00018-018-2969-7.Peer-Reviewed Original ResearchConceptsExtracellular matrix protein elastinAberrant vascular smooth muscle cell (VSMC) proliferationPatient induced pluripotent stem cellsInduced pluripotent stem cellsHuman disease modelingPluripotent stem cell (iPSC) technologyPluripotent stem cellsDrug screening approachesVascular proliferative diseasesVascular smooth muscle cell proliferationStem cell technologyProtein elastinReplenishable supplyDisruption of functionSmooth muscle cell proliferationDisease modelingStem cellsMuscle cell proliferationCell proliferationScreening approachTherapeutic developmentProliferative diseasesElastinBlood vessel dysfunctionTissue engineering
2017
Stem Cells in Cardiovascular Medicine: the Road to Regenerative Therapies
Anderson CW, Boardman N, Luo J, Park J, Qyang Y. Stem Cells in Cardiovascular Medicine: the Road to Regenerative Therapies. Current Cardiology Reports 2017, 19: 34. PMID: 28324469, PMCID: PMC5518932, DOI: 10.1007/s11886-017-0841-2.Peer-Reviewed Original ResearchConceptsCell technologyTissue-engineered productsStem cell technologyStem cell researchStem cellsDifferent stem cell sourcesCell researchMedical applicationsDysfunctional tissueStem cell sourceCell sourceRegenerative therapyTechnologyInherent characteristicsApplicationsCardiovascular medicineFunctionalityEngineeringBroad overviewCurrent trendsBasic differentiation
2014
Advancements in Induced Pluripotent Stem Cell Technology for Cardiac Regenerative Medicine
Suh CY, Wang Z, Bártulos O, Qyang Y. Advancements in Induced Pluripotent Stem Cell Technology for Cardiac Regenerative Medicine. Journal Of Cardiovascular Pharmacology And Therapeutics 2014, 19: 330-339. PMID: 24651517, PMCID: PMC4169350, DOI: 10.1177/1074248414523676.Peer-Reviewed Original ResearchCardiovascular diseaseCause of morbidityCardiac cellsCardiac regenerative medicineCardiac regenerative therapyPromising cell sourcePluripotent stem cell (iPSC) technologyDiseaseRegenerative therapyInduced pluripotent stem cell (iPSC) technologyCellular typesCell sourceTherapyStem cellsStem cell technologyPluripotent stem cellsRegenerative medicine