2019
Critical role of Lin28‐TNFR2 signalling in cardiac stem cell activation and differentiation
Xiang Q, Yang B, Li L, Qiu B, Qiu C, Gao X, Zhou H, Min W. Critical role of Lin28‐TNFR2 signalling in cardiac stem cell activation and differentiation. Journal Of Cellular And Molecular Medicine 2019, 23: 0-0. PMID: 30734494, PMCID: PMC6433861, DOI: 10.1111/jcmm.14202.Peer-Reviewed Original ResearchConceptsCardiac stem cell activationStem cell activationHuman inducible pluripotent stem cellsCardiac stem cell differentiationCSC activationStem cell differentiationInducible pluripotent stem cellsPluripotent stem cellsCardiac progenitor cellsCritical roleActivation of TNFR2Factor RNACell activationProtein Lin28Cardiomyocyte proteinsCell differentiationStem cellsProgenitor cellsStem cell-based therapiesCSC differentiationProtein expressionDifferentiationCell-based therapiesExpressionActivation
2011
Endometrial stem cell transplantation restores dopamine production in a Parkinson’s disease model
Wolff EF, Gao X, Yao KV, Andrews ZB, Du H, Elsworth JD, Taylor HS. Endometrial stem cell transplantation restores dopamine production in a Parkinson’s disease model. Journal Of Cellular And Molecular Medicine 2011, 15: 747-755. PMID: 20406327, PMCID: PMC2998585, DOI: 10.1111/j.1582-4934.2010.01068.x.Peer-Reviewed Original ResearchConceptsParkinson's diseaseDopaminergic neuronsWhole-cell patch-clamp recordingsCell patch-clamp recordingsDopamine metabolite concentrationsPD mouse modelStem cell transplantationDisease modelsSite of lesionParkinson's disease modelPyramidal cell bodiesPatch-clamp recordingsMesenchymal stem-like cellsAllogenic stem cellsStem cellsStem-like cellsCell transplantationStriatal dopamineNeural markers nestinCentral neuronsDopaminergic cellsDendritic projectionsDopamine synthesisDopamine productionMouse model
2008
Human Endometrial Stem Cells Transplantation in a Parkinson's Disease Mouse Model.
Wolff E, Gao X, Andrews Z, Yao K, Du H, Taylor H. Human Endometrial Stem Cells Transplantation in a Parkinson's Disease Mouse Model. Biology Of Reproduction 2008, 78: 120-120. DOI: 10.1093/biolreprod/78.s1.120d.Peer-Reviewed Original ResearchDisease mouse modelParkinson's disease mouse modelTyrosine hydroxylaseNestin antibodyStriatal dopamineDopaminergic cellsDopaminergic pathwaysMouse modelMouse brainTherapeutic potentialNeurogenic differentiationWhole-cell patch-clamp recordingsCell patch-clamp recordingsPotassium channelsReproductive-aged womenStem cell transplantationBarium-sensitive potassium channelsDOPAC/dopamineDisease modelsNOD-SCID miceSensitive potassium channelsStem cellsParkinson's disease modelPyramidal cell bodiesPatch-clamp recordings