2025
Multimodal identification of the mouse brain using simultaneous Ca2+ imaging and fMRI
Mandino F, Horien C, Shen X, Desrosiers-Grégoire G, Luo W, Markicevic M, Constable R, Papademetris X, Chakravarty M, Betzel R, Lake E. Multimodal identification of the mouse brain using simultaneous Ca2+ imaging and fMRI. Communications Biology 2025, 8: 665. PMID: 40287579, PMCID: PMC12033268, DOI: 10.1038/s42003-025-08037-4.Peer-Reviewed Original ResearchConceptsBOLD fMRIBOLD fMRI dataConnectome-based identificationCognitive neuroscientistsFMRI literatureHeterogeneous neurological conditionsWhole cortexFMRIMouse brainSimultaneous Ca2+ imagingCa2+ imagingAnimal modelsFluorescence calcium imagingCalcium imagingNeurological conditionsPersonalized treatmentNeuroimagingBOLDCortexNeuroscientistsBrainMiceMultimodal identificationCell-type specific signals
2024
Mapping the structure-function relationship along macroscale gradients in the human brain
Collins E, Chishti O, Obaid S, McGrath H, King A, Shen X, Arora J, Papademetris X, Constable R, Spencer D, Zaveri H. Mapping the structure-function relationship along macroscale gradients in the human brain. Nature Communications 2024, 15: 7063. PMID: 39152127, PMCID: PMC11329792, DOI: 10.1038/s41467-024-51395-6.Peer-Reviewed Original ResearchConceptsStructure-function correspondenceBrain regionsMacroscale gradientWhite matter connectivityHuman brain regionsStructure-function couplingNeural network propertiesAssociation cortexCognitive functionBridging neuroscienceFunctional coactivationOrganizational axisCortical thicknessHuman brainMotor cortexLanguage processingBrainCortexMotor functionNatural language processingNetwork propertiesMotorNeuroscienceNatural languageData repositories
2008
A Constrained Non-rigid Registration Algorithm for Use in Prostate Image-Guided Radiotherapy
Greene W, Chelikani S, Purushothaman K, Chen Z, Knisely J, Staib L, Papademetris X, Duncan J. A Constrained Non-rigid Registration Algorithm for Use in Prostate Image-Guided Radiotherapy. Lecture Notes In Computer Science 2008, 11: 780-788. PMID: 18979817, PMCID: PMC2790815, DOI: 10.1007/978-3-540-85988-8_93.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsArtificial IntelligenceHumansImaging, Three-DimensionalMalePattern Recognition, AutomatedProstatic NeoplasmsRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedRadiotherapy, Computer-AssistedReproducibility of ResultsSensitivity and SpecificitySubtraction TechniqueTomography, X-Ray ComputedConceptsTreatment planProstate image-guided radiotherapyOriginal treatment planRadiation dosageImage-guided radiotherapyTreatment daysRadiotherapy treatment plansCritical organsDifferent patientsPatient dataDifferent treatment daysBladderRectumProstateFemurBone motionCT imagesDosageReal patient dataPatientsRadiotherapy
2005
Spatial resolution, signal-to-noise ratio, and smoothing in multi-subject functional MRI studies
Scouten A, Papademetris X, Constable R. Spatial resolution, signal-to-noise ratio, and smoothing in multi-subject functional MRI studies. NeuroImage 2005, 30: 787-793. PMID: 16343951, DOI: 10.1016/j.neuroimage.2005.10.022.Peer-Reviewed Original ResearchConceptsSingle-subject studySpecific cortical regionsFunctional MRI studyBasic neuroscience studiesRandom effects analysisNeurosurgical interventionHemodynamic responseMRI studiesCortical activityCortical regionsFunctional MRIBrain functionFunctional anatomyNeurosurgical planningFunctional mappingSubtle activationClinical environmentGroup-level statisticsNeurophysiological underpinningsPartial volume effectsActivationNeuroscience studiesPatientsGroup statistics
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