2024
The anomalous effect of COVID-19 pandemic restrictions on the duration of untreated psychosis
Nicholls-Mindlin J, Hazan H, Zhou B, Li F, Ferrara M, Levine N, Riley S, Karmani S, Mathis W, Keshavan M, Srihari V. The anomalous effect of COVID-19 pandemic restrictions on the duration of untreated psychosis. BJPsych Open 2024, 10: e216. PMID: 39628123, DOI: 10.1192/bjo.2024.813.Peer-Reviewed Original ResearchTimelinePTC: Development of a unified interface for pathways to care collection, visualization, and collaboration in first episode psychosis
Mathis W, Ferrara M, Cahill J, Karmani S, Tayfur S, Srihari V. TimelinePTC: Development of a unified interface for pathways to care collection, visualization, and collaboration in first episode psychosis. PLOS ONE 2024, 19: e0302116. PMID: 39028697, PMCID: PMC11259254, DOI: 10.1371/journal.pone.0302116.Peer-Reviewed Original ResearchConceptsPathways to CareDuration of untreated psychosisManual transcription errorsDevelopment of targeted interventionsReduce duration of untreated psychosisHealthcare accessibility researchReal-time data entryImprove patient outcomesEpisode psychosisCare pathwaysPatient journeyHealthcare contextPatient outcomesPaper-basedConversion of collected dataFEP treatmentData collection processNew HavenData collection methodsData entryTranscription errorsUntreated psychosisOpen-source codebaseData collectionWeb-based tool
2022
Granular analysis of pathways to care and durations of untreated psychosis: A marginal delay model
Mathis W, Ferrara M, Burke S, Hyun E, Li F, Zhou B, Cahill J, Kline E, Keshavan M, Srihari V. Granular analysis of pathways to care and durations of untreated psychosis: A marginal delay model. PLOS ONE 2022, 17: e0270234. PMID: 36472968, PMCID: PMC9725156, DOI: 10.1371/journal.pone.0270234.Peer-Reviewed Original ResearchUntreated psychosisAntipsychotic prescriptionsEarly detection campaignsPatient characteristics influencesEarly detection effortsPatient characteristicsClinical nodesLonger DUPFunctional declineOutpatient programPsychosis onsetSpecialized treatmentPsychosisNumber of daysDetection campaignsNetworks of careHigh functioningPrescriptionEnrollmentPTCDurationStart dateReducing the Duration of Untreated Psychosis (DUP) in a US Community: A Quasi-Experimental Trial
Srihari VH, Ferrara M, Li F, Kline E, Gülöksüz S, Pollard JM, Cahill JD, Mathis WS, Sykes L, Walsh BC, McDermott G, Seidman LJ, Gueorguieva R, Woods SW, Tek C, Keshavan MS. Reducing the Duration of Untreated Psychosis (DUP) in a US Community: A Quasi-Experimental Trial. Schizophrenia Bulletin Open 2022, 3: sgab057. PMID: 35295656, PMCID: PMC8919192, DOI: 10.1093/schizbullopen/sgab057.Peer-Reviewed Original ResearchUntreated psychosisUS communitiesEarly detection campaignsFirst-episode servicesEffectiveness of careNumber of referralsQuasi-experimental trialEarly detection effortsOutcome measuresPsychosis onsetSecond quartileRapid enrollmentThird quartileQuartilePrEPDUPDetection campaignsDetection effortsReferralPsychosisU.S. communitiesTrialsAMPFESDurationCorrigendum to: Reducing the Duration of Untreated Psychosis (DUP) in a US Community: A Quasi-Experimental Trial
Srihari V, Ferrara M, Li F, Kline E, Gülöksüz S, Pollard J, Cahill J, Mathis W, Sykes L, Walsh B, McDermott G, Seidman L, Gueorguieva R, Woods S, Tek C, Keshavan M. Corrigendum to: Reducing the Duration of Untreated Psychosis (DUP) in a US Community: A Quasi-Experimental Trial. Schizophrenia Bulletin Open 2022, 3: sgac020. PMID: 39144776, PMCID: PMC11206056, DOI: 10.1093/schizbullopen/sgac020.Peer-Reviewed Original Research
2021
First help-seeking attempt before and after psychosis onset: measures of delay and aversive pathways to care
Ferrara M, Guloksuz S, Mathis WS, Li F, Lin IH, Syed S, Gallagher K, Shah J, Kline E, Tek C, Keshavan M, Srihari VH. First help-seeking attempt before and after psychosis onset: measures of delay and aversive pathways to care. Social Psychiatry And Psychiatric Epidemiology 2021, 56: 1359-1369. PMID: 33948678, PMCID: PMC8319102, DOI: 10.1007/s00127-021-02090-0.Peer-Reviewed Original ResearchConceptsPsychosis onsetNon-affective psychosisPsychosis risk syndromeEarly detection effortsAversive eventsAversive pathwaysProdromal sampleClinical characteristicsAntipsychotic treatmentEffective treatmentSociodemographic characteristicsSpecialized treatmentPsychosisProdromeOnsetTreatmentStructured interviewsOverall functioningFamily membersMeasures of delayEpisodesNew HavenSemi-structured interviewsHelp seekersPathway
2018
Blind Spots: Spatial analytics can identify nonrandom geographic variation in first episode psychosis program enrollments
Mathis WS, Woods S, Srihari V. Blind Spots: Spatial analytics can identify nonrandom geographic variation in first episode psychosis program enrollments. Early Intervention In Psychiatry 2018, 12: 1229-1234. PMID: 29927083, DOI: 10.1111/eip.12681.Peer-Reviewed Original ResearchConceptsPrimary care providersCare providersControl populationFirst episode psychosis programProgram enrollmentProgram catchment areaProvider Enumeration SystemPsychosis programSpecialty clinicRecruitment interventionsRisk populationsProgram enrolleesPositive findingsUS Census dataStatistical significanceHome addressEnrollmentEnrolleesProgram participantsPreliminary studyPopulationEnumeration systemFindingsProvidersClinic