2025
Phoenix Sepsis Criteria in Critically Ill Children: Retrospective Validation Using a United States Nine-Center Dataset, 2012–2018
Sanchez-Pinto L, Daniels L, Atreya M, Faustino E, Farris R, Geva A, Khemani R, Rogerson C, Shah S, Weiss S, Bennett T. Phoenix Sepsis Criteria in Critically Ill Children: Retrospective Validation Using a United States Nine-Center Dataset, 2012–2018. Pediatric Critical Care Medicine 2025, 26: e155-e165. PMID: 39982153, PMCID: PMC11792981, DOI: 10.1097/pcc.0000000000003675.Peer-Reviewed Original ResearchConceptsInternational Pediatric Sepsis Consensus ConferenceInternational Pediatric Sepsis Consensus Conference criteriaPhoenix criteriaCritically ill childrenSepsis criteriaPICU admissionCohort of critically ill childrenOrgan dysfunction scoreIll childrenMulticenter cohort studyHigher risk of mortalityMortality of patientsAge groupsIn-hospital mortalityRisk of mortalitySeverity of illnessDiscrimination of mortalityBloodstream infectionsSuspected infectionMulticenter cohortSeptic shockSepsis scoreDysfunction scorePatient subgroupsRetrospective analysis
2024
Protocol for the Catheter-Related Early Thromboprophylaxis With Enoxaparin (CRETE) Studies
Faustino E, Kandil S, Leroue M, Sochet A, Kong M, Cholette J, Nellis M, Pinto M, Chegondi M, Ramirez M, Schreiber H, Kerris E, Glau C, Kolmar A, Muisyo T, Sharathkumar A, Polikoff L, Silva C, Ehrlich L, Navarro O, Spinella P, Raffini L, Taylor S, McPartland T, Shabanova V, Network F. Protocol for the Catheter-Related Early Thromboprophylaxis With Enoxaparin (CRETE) Studies. Pediatric Critical Care Medicine 2024, 26: e95-e105. PMID: 39560771, PMCID: PMC11717624, DOI: 10.1097/pcc.0000000000003648.Peer-Reviewed Original ResearchRandomized clinical trialsDose of enoxaparinCatheter-relatedEarly thromboprophylaxisHigher risk of clinically relevant bleedingRisk of clinically relevant bleedingProphylactic doses of enoxaparinTherapeutic dose of enoxaparinOlder childrenMarkers of thrombin generationClinically relevant bleedingEfficacy of prophylaxisDeep venous thrombosisRemoval of CVCsCritically ill childrenPlatelet-poor plasmaPost hoc analysisGestational ageInternational unitsInstitutional review boardRelevant bleedingProphylactic doseUsual careAge-dependent heterogeneityVenous thrombosis
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