2024
Case report: Tremor in the placebo condition of a blinded clinical trial of intermittent theta-burst stimulation for cocaine use disorder
Steele V, Rotenberg A, Philip N, Hallett M, Stein E, Salmeron B. Case report: Tremor in the placebo condition of a blinded clinical trial of intermittent theta-burst stimulation for cocaine use disorder. Frontiers In Psychiatry 2024, 15: 1391771. PMID: 39045554, PMCID: PMC11263940, DOI: 10.3389/fpsyt.2024.1391771.Peer-Reviewed Original ResearchCocaine use disorderIntermittent theta burst stimulationTheta burst stimulationPlacebo responseUse disorderClinically relevant effectsBlind clinical trialClinical responseNew-onsetPlacebo conditionClinical trialsSham iTBSFunctional disordersPersistent tremorBurst stimulationCocaineDisordersShamStimulationTrialsWeak E-fieldsRelevant effectsTremorStimulating the posterior parietal cortex reduces self-reported risk-taking propensity in people with tobacco use disorder
LoFaro F, Jordan T, Apostol M, Steele V, Konova A, Petersen N. Stimulating the posterior parietal cortex reduces self-reported risk-taking propensity in people with tobacco use disorder. Addiction Neuroscience 2024, 12: 100160. PMID: 39329155, PMCID: PMC11426420, DOI: 10.1016/j.addicn.2024.100160.Peer-Reviewed Original ResearchPosterior parietal cortexTobacco use disorderRisk-taking propensityUse disorderWithin-session changesRisk behaviorsParietal cortexSingle-sessionRisk-takingBenefits of risk-takingDisordersVisual cortexCortexComprehensive measureSample participantsNeuromodulation protocolsDlPFCPerceptionBehaviorTobaccoParticipantsPropensityTherapeutic indicationsIndividualsFindings30. Individualizing Neuromodulation of the Dorsal Striatum in Methadone-Maintained Participants
Gresser K, Fang P, Kang D, Stevens M, Steele V. 30. Individualizing Neuromodulation of the Dorsal Striatum in Methadone-Maintained Participants. Biological Psychiatry 2024, 95: s111. DOI: 10.1016/j.biopsych.2024.02.265.Peer-Reviewed Original Research34. Intermittent Theta Burst Stimulation Normalizes Error Signals in the Anterior Cingulate Cortex for Individuals Receiving Methadone
Kang D, Gresser K, Fang P, Stevens M, Steele V. 34. Intermittent Theta Burst Stimulation Normalizes Error Signals in the Anterior Cingulate Cortex for Individuals Receiving Methadone. Biological Psychiatry 2024, 95: s112. DOI: 10.1016/j.biopsych.2024.02.269.Peer-Reviewed Original Research28. Scratching the Itch: An Acute Neuromodulation Session Reduces Drug Craving in Methadone-Maintained Individuals
Fang P, Gresser K, Kang D, Steele V. 28. Scratching the Itch: An Acute Neuromodulation Session Reduces Drug Craving in Methadone-Maintained Individuals. Biological Psychiatry 2024, 95: s110. DOI: 10.1016/j.biopsych.2024.02.263.Peer-Reviewed Original ResearchParameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity
Network A, Sangchooli A, Zare-Bidoky M, Jouzdani A, Schacht J, Bjork J, Claus E, Prisciandaro J, Wilson S, Wüstenberg T, Potvin S, Ahmadi P, Bach P, Baldacchino A, Beck A, Brady K, Brewer J, Childress A, Courtney K, Ebrahimi M, Filbey F, Garavan H, Ghahremani D, Goldstein R, Goudriaan A, Grodin E, Hanlon C, Haugg A, Heilig M, Heinz A, Holczer A, Van Holst R, Joseph J, Juliano A, Kaufman M, Kiefer F, Zonoozi A, Kuplicki R, Leyton M, London E, Mackey S, McClernon F, Mellick W, Morley K, Noori H, Oghabian M, Oliver J, Owens M, Paulus M, Perini I, Rafei P, Ray L, Sinha R, Smolka M, Soleimani G, Spanagel R, Steele V, Tapert S, Vollstädt-Klein S, Wetherill R, Witkiewitz K, Yuan K, Zhang X, Verdejo-Garcia A, Potenza M, Janes A, Kober H, Zilverstand A, Ekhtiari H. Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity. JAMA Psychiatry 2024, 81: 414-425. PMID: 38324323, PMCID: PMC11304510, DOI: 10.1001/jamapsychiatry.2023.5483.Peer-Reviewed Original ResearchTreatment developmentNeurobiology of drug addictionDrug cue reactivitySubstance use disordersBiomarkers of addictionCue reactivityAddictive disordersBiomarker developmentDrug addictionTreatment responseTreatment outcomesVisual cuesTask designCore aspectsAddictionClinical judgmentParticipant characteristicsDisordersOutcome predictorsClinical useMEDLINE databaseBiomarker qualificationSeveral biomarkersTranslational gapDatabase inceptionFunctional and structural effects of repetitive transcranial magnetic stimulation (rTMS) for the treatment of auditory verbal hallucinations in schizophrenia: A systematic review
Mehta D, Siddiqui S, Ward H, Steele V, Pearlson G, George T. Functional and structural effects of repetitive transcranial magnetic stimulation (rTMS) for the treatment of auditory verbal hallucinations in schizophrenia: A systematic review. Schizophrenia Research 2024, 267: 86-98. PMID: 38531161, PMCID: PMC11531343, DOI: 10.1016/j.schres.2024.03.016.Peer-Reviewed Original ResearchAuditory verbal hallucinationsRepetitive transcranial magnetic stimulationVerbal hallucinationsTranscranial magnetic stimulationTreatment-resistant auditory verbal hallucinationsAVH patientsTreatment of auditory verbal hallucinationsImpact of repetitive transcranial magnetic stimulationEmotion regulation regionsLanguage processing regionsAberrant neural activityHigh-frequency repetitive transcranial magnetic stimulationMagnetic stimulationRTMS interventionNeural substratesNeural effectsNeural mechanismsSham-controlled studySchizophreniaBrain activityNeuroimaging dataProcessing regionsNeuroimaging analysisNeuroimaging outcomesBrain abnormalities
2023
A systematic review and meta-analysis of neuromodulation therapies for substance use disorders
Mehta D, Praecht A, Ward H, Sanches M, Sorkhou M, Tang V, Steele V, Hanlon C, George T. A systematic review and meta-analysis of neuromodulation therapies for substance use disorders. Neuropsychopharmacology 2023, 49: 649-680. PMID: 38086901, PMCID: PMC10876556, DOI: 10.1038/s41386-023-01776-0.Peer-Reviewed Original ResearchRepetitive transcranial magnetic stimulationTranscranial direct current stimulationSubstance use disordersDeep brain stimulationDorsolateral prefrontal cortexUse disordersEffects of rTMSTreatment of SUDsSubstance useLong-term outcomesLeft dorsolateral prefrontal cortexTranscranial magnetic stimulationSystematic literature searchDirect current stimulationEffect sizeSubstance use outcomesAddiction neurocircuitryUncontrolled studiesDBS studiesNeuromodulation therapiesMagnetic stimulationPsychosocial treatmentsBrain stimulationTreatment durationAdministration protocolEditorial: New discoveries in the field of brain stimulation and addiction disorders
Kang D, Baker T, Steele V. Editorial: New discoveries in the field of brain stimulation and addiction disorders. Frontiers In Neuroscience 2023, 17: 1337773. PMID: 38094005, PMCID: PMC10716533, DOI: 10.3389/fnins.2023.1337773.Peer-Reviewed Original ResearchTranscranial Magnetic Stimulation for Reducing the Relative Reinforcing Value of Food in Adult Patients With Obesity Pursuing Metabolic and Bariatric Surgery: Protocol for a Pilot, Within-Participants, Sham-Controlled Trial
Bond D, Papasavas P, Raynor H, Grilo C, Steele V. Transcranial Magnetic Stimulation for Reducing the Relative Reinforcing Value of Food in Adult Patients With Obesity Pursuing Metabolic and Bariatric Surgery: Protocol for a Pilot, Within-Participants, Sham-Controlled Trial. JMIR Research Protocols 2023, 12: e50714. PMID: 37930756, PMCID: PMC10660230, DOI: 10.2196/50714.Peer-Reviewed Original ResearchRepetitive transcranial magnetic stimulationBrain reward processingRRV of foodTranscranial magnetic stimulationSham repetitive transcranial magnetic stimulationReward processingValue of foodMagnetic stimulationLeft dorsolateral prefrontal cortexNoninvasive brain stimulation techniqueINTERNATIONAL REGISTERED REPORT IDENTIFIERNeural reward circuitsSham-controlled crossover designFood reinforcementDorsolateral prefrontal cortexBrain stimulation techniquesSham rTMS conditionNeural measuresLine of researchActive repetitive transcranial magnetic stimulationFood rewardPrefrontal cortexPalatable foodReward circuitHigher food reinforcementParameter space in optimization of NIBS in addiction
Steele V. Parameter space in optimization of NIBS in addiction. Brain Stimulation 2023, 16: 140. DOI: 10.1016/j.brs.2023.01.082.Peer-Reviewed Original Research
2022
Characterizing Impulsivity in Individuals with Heroin Use Disorder
Kang T, Zhang Y, Zhao J, Li X, Jiang H, Niu X, Xie R, Ding X, Steele V, Yuan T. Characterizing Impulsivity in Individuals with Heroin Use Disorder. International Journal Of Mental Health And Addiction 2022, 22: 1530-1545. DOI: 10.1007/s11469-022-00941-8.Peer-Reviewed Original ResearchHeroin use disorderHealthy controlsUse disordersClinical severityMale healthy controlsSubstance use disordersDaily dosageRehabilitation hospitalFormer groupBIS-11 scoresMale participantsDisordersMale individualsSeverityParticipantsImpulsivityScoresTotal net scoreCognitive impulsivityGroupHospitalIGTIndividualsHow an Exemplar of Chronic Neuromodulation for Cocaine Use Disorder is a Path Forward for Treating Substance Use Disorders
Steele V. How an Exemplar of Chronic Neuromodulation for Cocaine Use Disorder is a Path Forward for Treating Substance Use Disorders. Biological Psychiatry 2022, 91: s37. DOI: 10.1016/j.biopsych.2022.02.110.Peer-Reviewed Original Research
2021
Response Inhibition Circuit Dysregulation in Substance Use Disorders Identified With Event-Related Potential-Derived Functional Connectivity
Steele V, Tootell A, Butler D, Fix S, Stevens M, Pearlson G, Bernat E. Response Inhibition Circuit Dysregulation in Substance Use Disorders Identified With Event-Related Potential-Derived Functional Connectivity. Biological Psychiatry 2021, 89: s350. DOI: 10.1016/j.biopsych.2021.02.873.Peer-Reviewed Original Research
2019
Accelerated Intermittent Theta-Burst Stimulation as a Treatment for Cocaine Use Disorder: A Proof-of-Concept Study
Steele VR, Maxwell AM, Ross TJ, Stein EA, Salmeron BJ. Accelerated Intermittent Theta-Burst Stimulation as a Treatment for Cocaine Use Disorder: A Proof-of-Concept Study. Frontiers In Neuroscience 2019, 13: 1147. PMID: 31736689, PMCID: PMC6831547, DOI: 10.3389/fnins.2019.01147.Peer-Reviewed Original ResearchCocaine use disorderTranscranial magnetic stimulationITBS sessionsDorsolateral prefrontal cortexUse disordersCocaine use behaviorCocaine usersIntermittent theta burst stimulationIntermittent theta burst stimulation (iTBS) protocolChronic cocaine usersCocaine-positive urine testsExecutive controlNeural underpinningsTheta burst stimulationCue reactivityResponse inhibitionAccelerated Intermittent Theta Burst StimulationCocaine usePrefrontal cortexDrugs of abuseTheta-burst stimulation protocolEffective treatmentITBSMagnetic stimulationSingle participantTranscranial electrical and magnetic stimulation (tES and TMS) for addiction medicine: A consensus paper on the present state of the science and the road ahead
Ekhtiari H, Tavakoli H, Addolorato G, Baeken C, Bonci A, Campanella S, Castelo-Branco L, Challet-Bouju G, Clark VP, Claus E, Dannon PN, Del Felice A, den Uyl T, Diana M, di Giannantonio M, Fedota JR, Fitzgerald P, Gallimberti L, Grall-Bronnec M, Herremans SC, Herrmann MJ, Jamil A, Khedr E, Kouimtsidis C, Kozak K, Krupitsky E, Lamm C, Lechner WV, Madeo G, Malmir N, Martinotti G, McDonald W, Montemitro C, Nakamura-Palacios EM, Nasehi M, Noël X, Nosratabadi M, Paulus M, Pettorruso M, Pradhan B, Praharaj SK, Rafferty H, Sahlem G, Salmeron BJ, Sauvaget A, Schluter RS, Sergiou C, Shahbabaie A, Sheffer C, Spagnolo PA, Steele VR, Yuan TF, van Dongen J, Van Waes V, Venkatasubramanian G, Verdejo-García A, Verveer I, Welsh J, Wesley MJ, Witkiewitz K, Yavari F, Zarrindast MR, Zawertailo L, Zhang X, Cha YH, George TP, Frohlich F, Goudriaan AE, Fecteau S, Daughters SB, Stein EA, Fregni F, Nitsche MA, Zangen A, Bikson M, Hanlon CA. Transcranial electrical and magnetic stimulation (tES and TMS) for addiction medicine: A consensus paper on the present state of the science and the road ahead. Neuroscience & Biobehavioral Reviews 2019, 104: 118-140. PMID: 31271802, PMCID: PMC7293143, DOI: 10.1016/j.neubiorev.2019.06.007.Peer-Reviewed Original ResearchConceptsSubstance use disordersNon-invasive brain stimulationConsensus paperAddiction medicineNovel treatment optionsMental health disordersTranscranial magnetic stimulationRecent FDA approvalHeterogeneity of methodsNIBS treatmentTreatment optionsFuture therapiesMagnetic stimulationBrain stimulationPreclinical neuroscienceClinical practiceHealth disordersFDA approvalNeural circuitsNeuromodulation toolBasic neuroscienceSUD researchStimulationSystematic literature reviewDisorders115. Developing Treatment Targets for Substance Use Disorders With Machine Learning Classifiers
Steele V. 115. Developing Treatment Targets for Substance Use Disorders With Machine Learning Classifiers. Biological Psychiatry 2019, 85: s48. DOI: 10.1016/j.biopsych.2019.03.129.Peer-Reviewed Original ResearchAddiction: Informing drug abuse interventions with brain networks.
Steele, V. R., Ding, X., & Ross, T. J. (2019). Addiction: Informing drug abuse interventions with brain networks. In B.C. Munsell, G. Wu, L. Bonilha, & P.J. Laurienti (Ed.) Connectomics: Applications to Neuroimaging (pp. 101-123). Elsevier.BooksChapter 6 Addiction: Informing drug abuse interventions with brain networks
Steele V, Ding X, Ross T. Chapter 6 Addiction: Informing drug abuse interventions with brain networks. 2019, 101-122. DOI: 10.1016/b978-0-12-813838-0.00006-6.ChaptersSubstance use disordersBrain networksNoninvasive brain stimulationDefault mode networkExecutive control networkRisk factorsEffective treatmentBrain stimulationUse disordersClinical modelBrain diseasesDiseaseEffective interventionsNew targetsInterventionAbuse interventionsReward processingFocal manipulation
2018
Reward Circuitry and Drug Addiction
Steele, V. R., Pariyadath, V., Goldstein, R. Z., & Stein, E. A. (2018). Reward Circuitry and Drug Addiction. In D.S. Charney, P. Sklar, J.D. Buxbaum, & E. J. Nestler (Ed.) Neurobiology of Mental Illness (pp. 587-600). Oxford University Press.Books