2000
Thrombospondin 2, a matricellular protein with diverse functions
Bornstein P, Armstrong L, Hankenson K, Kyriakides T, Yang Z. Thrombospondin 2, a matricellular protein with diverse functions. Matrix Biology 2000, 19: 557-568. PMID: 11102746, DOI: 10.1016/s0945-053x(00)00104-9.Peer-Reviewed Original ResearchConceptsMatrix metalloproteinase-2TSP2-null miceThrombospondin-2Matricellular proteinConnective tissueGrowth of tumorsConnective tissue elementsFragility of skinFunctional abnormalitiesTissue injuryMetalloproteinase-2MMP2 activityBleeding defectMiceCell surface receptorsGrowth factorAdult animalsMode of actionBone growthMarked disparityTissue elementsSubdermal tissueAbnormalitiesDermal fibroblastsTissue
1998
The Distribution of the Matricellular Protein Thrombospondin 2 in Tissues of Embryonic and Adult Mice
Kyriakides T, Zhu Y, Yang Z, Bornstein P. The Distribution of the Matricellular Protein Thrombospondin 2 in Tissues of Embryonic and Adult Mice. Journal Of Histochemistry & Cytochemistry 1998, 46: 1007-1015. PMID: 9705966, DOI: 10.1177/002215549804600904.Peer-Reviewed Original ResearchConceptsCell-matrix interactionsMatricellular protein thrombospondin-2Adult tissuesThrombospondin-2TSP2-null micePleiotropic phenotypesTissue-forming cellsCell movementEmbryonic developmentDermal fibroblastsPericellular environmentAdhesion defectsDay 15Connective tissueLeidig cellsTissue repairDay 18 embryosDermal cellsCells