2017
Nanopatterned Bulk Metallic Glass Biosensors
Kinser ER, Padmanabhan J, Yu R, Corona SL, Li J, Vaddiraju S, Legassey A, Loye A, Balestrini J, Solly DA, Schroers J, Taylor A, Papadimitrakopoulos F, Herzog RI, Kyriakides TR. Nanopatterned Bulk Metallic Glass Biosensors. ACS Sensors 2017, 2: 1779-1787. PMID: 29115132, DOI: 10.1021/acssensors.7b00455.Peer-Reviewed Original ResearchConceptsCyclic voltammetrySensitivity of biosensorsGlucose oxidase enzymeGlucose biosensor performanceBiocompatible biosensorSurface area enhancementBiosensor performanceElectrochemical measurementsElectrode sensitivityPt-BMGElectrode applicationsBiosensorOxidase enzymeVoltammetryBiocompatible materialsElectrodeΜA/Flat electrodesPlatinum-based bulk metallic glassArea enhancementControl electrodesBulk metallic glassOrders of magnitudeElectrical propertiesLow temperature
2014
Engineering Cellular Response Using Nanopatterned Bulk Metallic Glass
Padmanabhan J, Kinser ER, Stalter MA, Duncan-Lewis C, Balestrini JL, Sawyer AJ, Schroers J, Kyriakides TR. Engineering Cellular Response Using Nanopatterned Bulk Metallic Glass. ACS Nano 2014, 8: 4366-4375. PMID: 24724817, PMCID: PMC4046793, DOI: 10.1021/nn501874q.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiocompatible MaterialsBiomechanical PhenomenaCell AdhesionCell SurvivalCollagenCytoskeletonFibroblastsFibronectinsForeign-Body ReactionGlassGTP PhosphohydrolasesHuman Umbilical Vein Endothelial CellsHumansMetalsMiceMicroscopy, FluorescenceNanostructuresNanotechnologyNIH 3T3 CellsProtein EngineeringRhoA GTP-Binding ProteinConceptsBulk metallic glassCellular responsesFeature sizeMetallic glassesFocal adhesion densityCell traction forcesCytoskeletal remodelingFIB-SEM techniqueSubstrate stiffnessBiomechanical cuesThermoplastic formingMolecular pathwaysCell typesVersatile fabricationNondimensional analysisSubstrate nanotopographyCellular morphologyCell morphologyBiocompatible materialsCell functionForeign body responseNanoscale precisionCell sizeTissue repairFibroblasts