2024
Association Between Cognitive Trajectories and Subsequent Health Status, Depressive Symptoms, and Mortality Among Older Adults in the United States: Findings From a Nationally Representative Study
Zang E, Zhang Y, Wang Y, Wu B, Fried T, Becher R, Gill T. Association Between Cognitive Trajectories and Subsequent Health Status, Depressive Symptoms, and Mortality Among Older Adults in the United States: Findings From a Nationally Representative Study. The Journals Of Gerontology Series A 2024, 79: glae143. PMID: 38845419, PMCID: PMC11212484, DOI: 10.1093/gerona/glae143.Peer-Reviewed Original ResearchPoor health statusHealth statusDepressive symptomsOlder adultsHealth outcomesCognitive trajectoriesNational Health and Aging Trends StudyScreening of cognitive functionTrajectory groupsCognitive functionHigher depressive symptomsPopulation-based dataAdverse health outcomesNationally representative cohortGroup-based trajectory modelingHigher mortality riskAssociated with higher riskNationally-representative studyLogistic regression modelsTrends StudyRepresentative cohortGlobal cognitionLiving respondentsRegular screeningMortality risk
2019
Medication Appropriateness in Vulnerable Older Adults: Healthy Skepticism of Appropriate Polypharmacy
Fried TR, Mecca MC. Medication Appropriateness in Vulnerable Older Adults: Healthy Skepticism of Appropriate Polypharmacy. Journal Of The American Geriatrics Society 2019, 67: 1123-1127. PMID: 30697698, PMCID: PMC6561813, DOI: 10.1111/jgs.15798.Peer-Reviewed Original ResearchConceptsNumber of medicationsAppropriate polypharmacyOlder adultsMedication benefitsComplex medication regimensMultiple chronic conditionsVulnerable older adultsMedication appropriatenessUnderestimate harmsInappropriate medicationsMore medicationsAdverse eventsMore observational studiesMedication regimensComplex regimenAdverse outcomesAppropriate medicationChronic conditionsMedications resultsObservational studyPolypharmacyMedicationsHealth outcomesCorrect medicationLikelihood of harm