2024
Artificial Sweeteners in US-Marketed Oral Nicotine Pouch Products: Correlation With Nicotine Contents and Effects on Product Preference
Jabba S, Silinski P, Yang A, Ouyang W, Jordt S. Artificial Sweeteners in US-Marketed Oral Nicotine Pouch Products: Correlation With Nicotine Contents and Effects on Product Preference. Nicotine & Tobacco Research 2024, ntae293. PMID: 39656927, DOI: 10.1093/ntr/ntae293.Peer-Reviewed Original ResearchOral nicotine pouchesWild-type miceReceptor-deficient miceEffects of nicotineIncreased nicotine consumptionSensory effects of nicotineNicotine pouch productsArtificial sweetenersDeficient miceNicotine consumptionSweet taste perceptionNicotine pouchesHigh-nicotineMiceNicotineSmokeless tobaccoAcesulfame-KLiquid chromatography-mass spectrometryWild-typeNicotine contentTaste perceptionTobacco productsArtificial sweeteners acesulfame-KReduced aversionStronger aversion
2023
Effect Of Comt Genetic Background And Stress On Pain Following Tibial Fracture
Chen J, Wu Y, Wang Y, Sandu C, Gu E, Jordt S, Terrando N, Nackley A. Effect Of Comt Genetic Background And Stress On Pain Following Tibial Fracture. Journal Of Pain 2023, 24: 30. DOI: 10.1016/j.jpain.2023.02.098.Peer-Reviewed Original ResearchDepressive-like behaviorStress fracture groupTail suspension testTibial fracturesSham stressAbdominal sitesSuspension testSham–sham groupVon Frey filamentsWild-type miceAbdominal hyperalgesiaMechanical hyperalgesiaMechanical hypersensitivityImmobility timeWT miceBody painType miceHyperalgesiaPainSpinal needleActivity genotypeMonth time periodGenetic inhibitionStress groupCOMT genotype
2009
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma
Caceres AI, Brackmann M, Elia MD, Bessac BF, del Camino D, D'Amours M, Witek JS, Fanger CM, Chong JA, Hayward NJ, Homer RJ, Cohn L, Huang X, Moran MM, Jordt SE. A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 9099-9104. PMID: 19458046, PMCID: PMC2684498, DOI: 10.1073/pnas.0900591106.Peer-Reviewed Original ResearchConceptsAsthmatic airway inflammationAirway inflammationAirway hyperreactivityAllergen challengeHC-030031Airway allergen challengeEndogenous TRPA1 agonistsMurine ovalbumin modelImpaired inflammatory responseTreatment of asthmaRole of TRPA1Wild-type miceAirway epithelial functionAllergic inflammatory conditionsPromising pharmacological targetNeuronal ion channelsLipid peroxidation productsIon channelsAllergic asthmaAirway exposureEosinophil infiltrationLeukocyte infiltrationContractile stimuliInflammatory disordersOvalbumin model
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