2024
“Dark” Pathways of Protein Transnitrosylation Injure Synapses in Alzheimer’s Disease: Mechanism and Potential Treatment
LIPTON S. “Dark” Pathways of Protein Transnitrosylation Injure Synapses in Alzheimer’s Disease: Mechanism and Potential Treatment. 2024, pl. DOI: 10.14869/toxpt.51.1.0_pl.Peer-Reviewed Original ResearchAlzheimer's diseaseDisruption of protein functionUbiquitin-protein hydrolaseS-nitrosylationS-nitrosylation reactionLoss of synapsesCorrelated to cognitive declineGuanosine triphosphataseMitochondrial fragmentationAD brainProtein functionAmyloid-betaAggregated proteinsProtein hydrolaseSynapse lossSynaptic lossBioenergetic compromiseSynaptic damageTransnitrosylation reactionsProteinUCH-L1Environmental factorsEnzymeAlzheimerCascade
2012
Redox control of protein misfolding and mitochondrial fragmentation via s-nitrosylation: Implications for synaptic damage in neurodegenerative diseases
Lipton⁎ S. Redox control of protein misfolding and mitochondrial fragmentation via s-nitrosylation: Implications for synaptic damage in neurodegenerative diseases. Free Radical Biology And Medicine 2012, 53: s29. DOI: 10.1016/j.freeradbiomed.2012.08.133.Peer-Reviewed Original Research