Research & Publications
Dr. Halene is a physician-scientist who received her MD and PhD degrees at Eberhardt-Karls-University in Tübingen, Germany. She subsequently completed a postdoctoral fellowship in the laboratory of Donald B. Kohn at CHLA in Los Angeles and her residency in internal medicine at Yale New Haven Hospital. She completed her fellowship in hematology/oncology at Yale and joined the ladder faculty at YSM as an assistant professor in 2010. At that time she was also named director of the Hematology Tissue Bank for Yale Cancer Center. She was promoted to associate professor in 2016 and subsequently served as interim chief of the Section of Hematology prior to her appointment as chief of that section in 2020.
Her laboratory studies hematopoiesis and myelopoiesis and in particular how mutations in splicing factors and perturbations in RNA modifications contribute to hematologic malignancies such as myelodysplasia and leukemia. Dr. Halene, in collaboration with the Flavell laboratory in the YSM Department of Immunobiology, has developed the first efficient xenotransplantation model in humanized mice to study myelodysplasia and enable testing of novel drug treatments. Dr. Halene’s research has garnered significant attention from the international community, as evidenced by numerous invited speaking engagements, an invitation to serve as a section editor on myeloid malignancies for a major journal, and publications in top tier journals in her field. In 2015 she was presented with the Sir William Osler Young Investigator Award and in 2019 was elected a member of the Interurban Clinical Club.
Dr. Halene is director of the DeLuca Center for Innovation in Hematology Research. Through generous funding from The Frederick A. DeLuca Foundation, the center has established a comprehensive biospecimen bank, awarded pilot and career development grant funding to advance cutting-edge discoveries in hematologic malignancies and classical hematologic disorders.
Education & Training
- FellowYale University School of Medicine (2006)
- ResidentYale-New Haven Hospital (2002)
- Postdoctoral AssociateChildrens Hospital Los Angeles (2000)
- ResidentEberhard-Karls-University (1997)
- PhDEberhard-Karls-Universitat Tubingen (1997)
- MDEberhard-Karls-Universitat Tubingen (1995)
Honors & Recognition
|Member||Interurban Clinical Club||2019|
|Sir William Osler Young Investigator Award||Interurban Clinical Club||2015|
|Career Development Award||Claude D. Pepper Older Americans Independence Center||2010|
|T32 Research Fellow||NIH||2003|
|Scholarship||American Heart Association||1993|
|Scholar||German Academic Exchange Service (DAAD)||1990|
|Scholar||Studienstiftung des Deutschen Volkes||1988|
|External Advisory Board, Cellular & Molecular Biology Masters Program, University of New Haven||Board Member||2021 - Present|
|Music Haven. A non-profit organization providing free string instrument lesson and music education to children in New Haven Public Schools (http://musichavenct.org)||Member, Board of Directors||2014 - 2021|