2023
Nuclear envelope assembly relies on CHMP-7 in the absence of BAF–LEM-mediated hole closure
Barger S, Penfield L, Bahmanyar S. Nuclear envelope assembly relies on CHMP-7 in the absence of BAF–LEM-mediated hole closure. Journal Of Cell Science 2023, 136: jcs261385. PMID: 37795681, PMCID: PMC10668030, DOI: 10.1242/jcs.261385.Peer-Reviewed Original ResearchConceptsNuclear envelope assemblySpindle microtubulesNE assemblyEnvelope assemblyC. elegans oocytesLEM-2C. elegansHelix domainBAF-1Family proteinsNucleoplasmic poolNE formationDistinct rolesMicrotubulesAdditional roleNE stabilityPermeability barrierRedundant mechanismsBAFProteinEmbryo survivalBindingAssemblyElegansAutointegration
2022
Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth
Mauro MS, Celma G, Zimyanin V, Magaj MM, Gibson KH, Redemann S, Bahmanyar S. Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth. ELife 2022, 11: e75513. PMID: 35852146, PMCID: PMC9296133, DOI: 10.7554/elife.75513.Peer-Reviewed Original ResearchConceptsNuclear pore complexNPC assemblyMembrane biogenesisNE formationNPC densityNuclear pore complex assemblyEndoplasmic reticulumPore complex assemblyNuclear growthPore complexNDC1Redundant rolesComplex assemblyNPC numberBiogenesisMembrane incorporationFast turnoverNuclear formationBilayer lipidsNup53Membrane synthesisFirst divisionAssemblyGrowthNup160