2025
Neural Variability and Cognitive Control in Individuals With Opioid Use Disorder
Ye J, Mehta S, Peterson H, Ibrahim A, Saeed G, Linsky S, Kreinin I, Tsang S, Nwanaji-Enwerem U, Raso A, Arora J, Tokoglu F, Yip S, Hahn C, Lacadie C, Greene A, Constable R, Barry D, Redeker N, Yaggi H, Scheinost D. Neural Variability and Cognitive Control in Individuals With Opioid Use Disorder. JAMA Network Open 2025, 8: e2455165. PMID: 39821393, PMCID: PMC11742521, DOI: 10.1001/jamanetworkopen.2024.55165.Peer-Reviewed Original ResearchConceptsDecreased cognitive controlCognitive controlOpioid use disorderCueing paradigmResting-stateHC participantsUse disorderBrain statesBrain dynamicsHealthy controlsNeural mechanismsCognitive processesNeural variabilityFMRIBehavioral implicationsImpaired abilityBrainAccuracy scoresMagnetic resonance imagingDynamic alterationsParticipantsCase-control studyDisordersParadigmImpacts millions
2024
Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances
McCurdy L, Yip S, Worhunsky P, Zhai Z, Kim S, Strathearn L, Potenza M, Mayes L, Rutherford H. Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances. Journal Of Psychiatric Research 2024, 171: 126-133. PMID: 38277872, PMCID: PMC10922955, DOI: 10.1016/j.jpsychires.2024.01.024.Peer-Reviewed Original ResearchConceptsResponses to infant stimuliInfant stimuliMaternal behaviorAffective processesBrain regionsPsychological processesEmotional responsesFunctional magnetic resonance imagingPotential neural targetsInfant emotional expressionsMaternal emotional responsivenessSubstance-use statusAssociated with difficultiesSocial-emotional developmentInfant social-emotional developmentMaternal substance useInfant facesCognitive processesImprove child outcomesEmotional expressionEmotional intensityNeural targetsSubstance useGroups of mothersChild outcomes
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