2025
Quantifying associations between socio-spatial factors and cognitive development in the ABCD cohort
Osayande N, Marotta J, Aggarwal S, Kopal J, Holmes A, Yip S, Bzdok D. Quantifying associations between socio-spatial factors and cognitive development in the ABCD cohort. Nature Computational Science 2025, 5: 221-233. PMID: 40114020, DOI: 10.1038/s43588-025-00774-0.Peer-Reviewed Original ResearchConceptsAdolescent Brain Cognitive Development StudyCognitive developmentUS Census dataCognitive Development StudyBayesian multilevel regressionPost-stratificationSocio-spatial factorsSociodemographic disparitiesSocioeconomic statusABCD cohortSociodemographic variablesBayesian multilevel modelsQuantify associationsInter-individual differencesMultilevel regressionPublic healthMultilevel modelsCensus dataInterpretation of model predictionsDemographic groupsDevelopment studiesHolistic explanationHomogeneous representationModeling frameworkMounting demand
2024
Bayesian subtyping for multi-state brain functional connectome with application on preadolescent brain cognition
Chen T, Zhao H, Tan C, Constable T, Yip S, Zhao Y. Bayesian subtyping for multi-state brain functional connectome with application on preadolescent brain cognition. Biostatistics 2024, 26: kxae045. PMID: 39656842, PMCID: PMC11823269, DOI: 10.1093/biostatistics/kxae045.Peer-Reviewed Original ResearchAdolescent Brain Cognitive DevelopmentVariational inference algorithmApproximate posterior inferenceFunctional connectivityMultiple cognitive statesInference algorithmExtensive simulationsNetwork topologyNetwork featuresFunctional network patternsBrain functional connectomeBrain functional connectivityEstimation accuracySubgroups of individualsNeurobiological heterogeneityCognitive profileCognitive statesConverging evidencePosterior inferenceDetection alternativesNeuroscience literatureBrain cognitionFunctional connectomeNetworkCognitive development
2023
Identification of a Composite Latent Dimension of Reward and Impulsivity Across Clinical, Behavioral, and Neurobiological Domains Among Youth
Kohler R, Lichenstein S, Cheng A, Holmes A, Bzdok D, Pearlson G, Yip S. Identification of a Composite Latent Dimension of Reward and Impulsivity Across Clinical, Behavioral, and Neurobiological Domains Among Youth. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2023, 9: 407-416. PMID: 38052266, PMCID: PMC11149944, DOI: 10.1016/j.bpsc.2023.11.008.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderDisruptive behavior disordersAnterior cingulate responsesLatent dimensionsAnticipatory reward processingDeficit hyperactivity disorderSingle latent dimensionRisk-taking behaviorNegative urgencyExecutive functionIndividual differencesNeurobiological domainsReward anticipationCingulate responseReward processingAdolescent brainCognitive developmentNeural substratesHyperactivity disorderDevelopmental trajectoriesEarly adolescenceMultivariate patternsReward processesBehavioral variablesBehavior disorder
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