2023
Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo
May D, Yun S, Gonzalez D, Park S, Chen Y, Lathrop E, Cai B, Xin T, Zhao H, Wang S, Gonzalez L, Cockburn K, Greco V. Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo. ELife 2023, 12: e83444. PMID: 36880644, PMCID: PMC10027315, DOI: 10.7554/elife.83444.Peer-Reviewed Original ResearchConceptsStem cell differentiationCell differentiationStem cell compartmentCompaction changesChromatin compaction statesDynamic transcriptional statesCell compartmentChromatin architectureCell cycle statusChromatin rearrangementNascent RNATranscriptional burstingTranscriptional statesLive imagingTissue contextGene expressionDifferentiating cellsGlobal remodelingIndividual cellsCycle statusStem cellsDifferentiation statusDifferentiationCellsMorphological changes
2022
Double knockin mice show NF-ÎşB trajectories in immune signaling and aging
Rahman S, Aqdas M, Martin E, Ardori F, Songkiatisak P, Oh K, Uderhardt S, Yun S, Claybourne Q, McDevitt R, Greco V, Germain R, Tessarollo L, Sung M. Double knockin mice show NF-ÎşB trajectories in immune signaling and aging. Cell Reports 2022, 41: 111682. PMID: 36417863, PMCID: PMC9764224, DOI: 10.1016/j.celrep.2022.111682.Peer-Reviewed Original Research
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