2016
A randomized factorial trial of disulfiram and contingency management to enhance cognitive behavioral therapy for cocaine dependence
Carroll KM, Nich C, Petry NM, Eagan DA, Shi JM, Ball SA. A randomized factorial trial of disulfiram and contingency management to enhance cognitive behavioral therapy for cocaine dependence. Drug And Alcohol Dependence 2016, 160: 135-142. PMID: 26817621, PMCID: PMC4767616, DOI: 10.1016/j.drugalcdep.2015.12.036.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCocaine outcomesCocaine dependenceCombination of CMDouble-blind clinical trialBehavioral therapyCommunity-based outpatient clinicsUrine sample testingBlind clinical trialSustained treatment effectContingency managementDSM-IV criteriaRandomized factorial trialCurrent cocaine dependenceWeekly individual sessionsCocaine use disorderSecondary outcomesPrimary outcomeYear followOutpatient clinicAddition of disulfiramClinical trialsUse disordersCBT treatmentFactorial trial
2014
Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram
DeVito EE, Babuscio TA, Nich C, Ball SA, Carroll KM. Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram. Drug And Alcohol Dependence 2014, 145: 156-167. PMID: 25457739, PMCID: PMC4268325, DOI: 10.1016/j.drugalcdep.2014.10.007.Peer-Reviewed Original ResearchMeSH KeywordsAdultBehavior TherapyCocaine-Related DisordersDisulfiramFemaleFollow-Up StudiesHumansMaleMiddle AgedPsychotherapySex CharacteristicsTreatment OutcomeConceptsRandomized clinical trialsClinical trialsClinical outcomesTreatment outcomesCocaine dependenceBehavioral therapyBehavioral treatment conditionsPoor treatment outcomesEvidence-based treatmentsGender differencesWidespread clinical implementationPoor outcomePharmacological treatmentMedication conditionAddiction pharmacotherapyCocaine useSecondary analysisBehavioral treatmentClinical implementationWomenCareful assessmentDisulfiramOutcomesTrialsMenComputer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone
Carroll KM, Kiluk BD, Nich C, Gordon MA, Portnoy GA, Marino DR, Ball SA. Computer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone. American Journal Of Psychiatry 2014, 171: 436-444. PMID: 24577287, PMCID: PMC4042674, DOI: 10.1176/appi.ajp.2013.13070987.Peer-Reviewed Original ResearchMeSH KeywordsAdultCocaine-Related DisordersCognitive Behavioral TherapyCombined Modality TherapyFemaleHumansMaleMethadoneMiddle AgedNarcoticsTherapy, Computer-AssistedTreatment OutcomeConceptsCocaine-dependent individualsCognitive behavioral therapyMethadone maintenanceCommunity-based outpatient clinicsPrevious pilot trialMethadone maintenance programStandard methadone maintenanceDisseminable strategyDefinitive trialOutpatient clinicClinical trialsEffective adjunctPilot trialTreatment terminationTreatment retentionBetter outcomesConsecutive weeksCBT4CBTWeekly accessAddiction treatmentDurable effectsTrialsSubstance usersStatistical significanceMethadoneToward empirical identification of a clinically meaningful indicator of treatment outcome: Features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes
Carroll KM, Kiluk BD, Nich C, DeVito EE, Decker S, LaPaglia D, Duffey D, Babuscio TA, Ball SA. Toward empirical identification of a clinically meaningful indicator of treatment outcome: Features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes. Drug And Alcohol Dependence 2014, 137: 3-19. PMID: 24556275, PMCID: PMC4042667, DOI: 10.1016/j.drugalcdep.2014.01.012.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsClinical Trials as TopicCocaine-Related DisordersEmpirical ResearchFollow-Up StudiesHumansQuality Indicators, Health CareTreatment Outcome
2013
The Recovery Line: A pilot trial of automated, telephone-based treatment for continued drug use in methadone maintenance
Moore BA, Fazzino T, Barry DT, Fiellin DA, Cutter CJ, Schottenfeld RS, Ball SA. The Recovery Line: A pilot trial of automated, telephone-based treatment for continued drug use in methadone maintenance. Journal Of Substance Use And Addiction Treatment 2013, 45: 63-69. PMID: 23375114, PMCID: PMC3642223, DOI: 10.1016/j.jsat.2012.12.011.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultAutomationCocaine-Related DisordersFeasibility StudiesFemaleHumansMaleMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient Acceptance of Health CarePatient SatisfactionPilot ProjectsSubstance Abuse DetectionTelephoneTherapy, Computer-AssistedConceptsMethadone maintenanceLarge clinical trialsTelephone-based treatmentCurrent pilot studyPatient satisfactionClinical trialsPatient utilizationComputer-based treatmentPilot trialInitial efficacyInteractive voice response systemDrug usePatientsScreen outcomesVoice response systemPilot studyIllicit drugsTreatmentDaily useTrialsEfficacyOpioidsAbstinenceRecovery lineCocaine
2012
Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: A randomized placebo-controlled trial
Carroll KM, Nich C, Shi JM, Eagan D, Ball SA. Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: A randomized placebo-controlled trial. Drug And Alcohol Dependence 2012, 126: 224-231. PMID: 22695473, PMCID: PMC3461119, DOI: 10.1016/j.drugalcdep.2012.05.019.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DeterrentsAlcohol DrinkingCocaine-Related DisordersCounselingDemographyDiagnostic and Statistical Manual of Mental DisordersDisulfiramDouble-Blind MethodFemaleFollow-Up StudiesHumansMaleMethadoneNarcoticsOpiate Substitution TreatmentPatient ComplianceRegression AnalysisSelf-Help GroupsSocioeconomic FactorsSubstance Abuse DetectionTreatment OutcomeConceptsMethadone maintenance programEfficacy of disulfiramAlcohol use disorderCocaine useStandard counselingUse disordersCommunity-based methadone maintenance programRandomized placebo-controlled trialPlacebo-controlled trialCurrent alcohol use disorderTwelve-step facilitationCocaine-negative urinesLess cocaine useMethadone maintenanceStep FacilitationCocaine-dependent individualsPlaceboBetter outcomesDisulfiram efficacyTreatment approachesFactorial trialDisulfiramMaintenance programRelative efficacyCocaine users
2005
Practice Makes Progress? Homework Assignments and Outcome in Treatment of Cocaine Dependence
Carroll KM, Nich C, Ball SA. Practice Makes Progress? Homework Assignments and Outcome in Treatment of Cocaine Dependence. Journal Of Consulting And Clinical Psychology 2005, 73: 749-755. PMID: 16173864, PMCID: PMC2365906, DOI: 10.1037/0022-006x.73.4.749.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultCocaine-Related DisordersCognitive Behavioral TherapyFemaleHumansPeriodicityPractice, PsychologicalTreatment Outcome
2004
Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients: A Randomized Placebo-Controlled Trial
Carroll KM, Fenton LR, Ball SA, Nich C, Frankforter TL, Shi J, Rounsaville BJ. Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients: A Randomized Placebo-Controlled Trial. JAMA Psychiatry 2004, 61: 264-272. PMID: 14993114, PMCID: PMC3675448, DOI: 10.1001/archpsyc.61.3.264.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DeterrentsCocaine-Related DisordersCognitive Behavioral TherapyDisulfiramDouble-Blind MethodFemaleHumansMaleOutpatientsPlacebosTreatment OutcomeConceptsCocaine useGeneral populationCocaine dependenceEfficacy of disulfiramUrine toxicology screenOutpatient substance abuse treatment programsBehavior therapyConcurrent alcohol useSubstance abuse treatment programsCurrent cocaine dependenceCognitive behavior therapyDisulfiram useRandomized PlaceboDisulfiram therapyMedication complianceToxicology screenIdentical capsulesEffective therapyPlaceboCocaine-dependent individualsSelf-reported frequencyPromising treatmentPlacebo conditionInterpersonal psychotherapyTherapy
2000
One‐year follow‐up of disulfiram and psychotherapy for cocaine‐alcohol users: sustained effects of treatment
Carroll K, Nich C, Ball S, McCance E, Frankforter T, Rounsaville B. One‐year follow‐up of disulfiram and psychotherapy for cocaine‐alcohol users: sustained effects of treatment. Addiction 2000, 95: 1335-1349. PMID: 11048353, DOI: 10.1046/j.1360-0443.2000.95913355.x.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentTwelve-step facilitationInitiation of abstinenceAlcohol useSubstance abuse treatment centersFrequency of cocaineAlcohol-dependent individualsClinical managementMain effectBrief treatmentEfficacy of disulfiramUrine toxicology screenCessation of treatmentBreathalyzer testEnd of treatmentOutcomes 1 yearAbstinencePercentage of daysEffect of treatmentCocaineLong-term benefitsToxicology screenTreatment centersBetter outcomesBrief periodA general system for evaluating therapist adherence and competence in psychotherapy research in the addictions
Carroll K, Nich C, Sifry R, Nuro K, Frankforter T, Ball S, Fenton L, Rounsaville B. A general system for evaluating therapist adherence and competence in psychotherapy research in the addictions. Drug And Alcohol Dependence 2000, 57: 225-238. PMID: 10661673, DOI: 10.1016/s0376-8716(99)00049-6.Peer-Reviewed Original ResearchConceptsTherapist adherenceRandomized clinical trialsSubstance use disordersDrug abuse treatmentYale AdherenceClinical trialsPharmacotherapy researchUse disordersBehavioral treatmentAbuse treatmentClinical researchAdherenceTreatmentComparison treatmentCompetence scoresExcellent reliabilityAddictionDiscriminant validityCompetence ScaleFactor structurePsychotherapy research
1998
Types of Abuse and Cocaine Use in Pregnant Women
Jantzen K, Ball S, Leventhal J, Schottenfeld R. Types of Abuse and Cocaine Use in Pregnant Women. Journal Of Substance Use And Addiction Treatment 1998, 15: 319-323. PMID: 9650140, DOI: 10.1016/s0740-5472(97)00198-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultChildChild AbuseChild Abuse, SexualCocaine-Related DisordersConnecticutFemaleHospitals, UrbanHumansPregnancyPregnancy ComplicationsConceptsCocaine useCurrent cocaine useAge of onsetPerinatal carePregnant womenSexual abuseHospital clinicOnset of abuseLifetime cocaine useHistory of abuseSubstance abuseChildhood sexual abuseChildhoodWomenFrequency of abuseExperiences of abusePhysical abuseTypes of abuseSeverityAbuseOnsetAssociationAbuse experiencesPregnancy