Interactive association of posttraumatic stress disorder, apolipoprotein ε4 genotype, and age on cognitive functioning
Lawrence K, Rippey C, Welikson B, Pietrzak R, Adams T. Interactive association of posttraumatic stress disorder, apolipoprotein ε4 genotype, and age on cognitive functioning. International Journal Of Geriatric Psychiatry 2023, 38: e5888. PMID: 36757293, PMCID: PMC10168127, DOI: 10.1002/gps.5888.Peer-Reviewed Original ResearchMeSH KeywordsAgedApolipoprotein E4CognitionCognitive DysfunctionGenotypeHumansNeuropsychological TestsStress Disorders, Post-TraumaticConceptsPosttraumatic stress disorderThree-way interactionCognitive functioningStress disorderOlder participantsTreatment of PTSDMain effectProbable posttraumatic stress disorderAge-related cognitive impairmentAPOE ε4U.S. military veteransApolipoprotein ε4 genotypeCognitive deficitsPsychomotor performanceAge-related associationsInteractive associationsVeterans StudyMilitary veteransCognitive impairmentPreliminary evidenceTwo-way interactionAPM performanceΕ4 carriersAnalysis of covarianceFunctioning