2025
Predicting Mortality in Patients Hospitalized With Acute Myocardial Infarction: From the National Cardiovascular Data Registry
Faridi K, Wang Y, Minges K, Smilowitz N, McNamara R, Kontos M, Wang T, Connors A, Clary J, Osborne A, Pereira L, Curtis J, Blankinship K, Mayfield J, Abbott J. Predicting Mortality in Patients Hospitalized With Acute Myocardial Infarction: From the National Cardiovascular Data Registry. Circulation Cardiovascular Quality And Outcomes 2025, 18: e011259. PMID: 39801472, PMCID: PMC11919567, DOI: 10.1161/circoutcomes.124.011259.Peer-Reviewed Original ResearchConceptsNational Cardiovascular Data Registry Chest Pain-MI RegistryIn-hospital mortalityAcute myocardial infarctionChest Pain-MI RegistryOut-of-hospital cardiac arrestRisk scoreRisk-standardized modelsNational Cardiovascular Data RegistryAcute MI hospitalizationsPatient characteristicsMyocardial infarctionContemporary risk modelsIn-hospital mortality rateMI hospitalizationST-segment elevation MIIndependent predictor of mortalityMortality risk predictionSystolic blood pressureMortality riskPredictors of mortalityHospital volumePatient prognosticationData RegistryRisk modelSimplified risk score
2022
Abnormal left atrial body stiffness is predicted by appendage size: impact of appendage occlusion on left atrial mechanics assessed by pressure-volume analysis
Bregasi A, Freeman JV, Curtis JP, Akar JG, Ortiz-Leon XA, Maia JH, Higgins AY, Matthews RV, Sinusas AJ, McNamara RL, Sugeng L, Lin BA. Abnormal left atrial body stiffness is predicted by appendage size: impact of appendage occlusion on left atrial mechanics assessed by pressure-volume analysis. AJP Heart And Circulatory Physiology 2022, 323: h559-h568. PMID: 35960632, PMCID: PMC9576173, DOI: 10.1152/ajpheart.00083.2022.Peer-Reviewed Original ResearchConceptsLeft atrial appendage occlusionLA stiffnessAppendage occlusionLA appendageLA mechanicsTransesophageal echocardiographyPressure-volume analysisPercutaneous left atrial appendage occlusionAdverse atrial remodelingAtrial appendage occlusionLeft atrial appendageLA volume measurementsAtrial cardiomyopathyBaseline characteristicsLA complianceAtrial remodelingClinical outcomesAtrial appendageAtrial mechanicsCardiac performancePathophysiological roleBaseline parametersMagnitude of increaseAppendage sizeOcclusion
2021
IN-HOSPITAL MORTALITY RISK PREDICTION FOR PERCUTANEOUS CORONARY INTERVENTIONS: AN UPDATED MODEL FROM THE NCDR CATHPCI REGISTRY
Dominguez Y, Minges K, Wang Y, McNamara R, Spertus J, Dehmer G, Messenger J, Mercado N, Lavin K, Pierre D, Anderson C, Blankinship K, Clary J, Osborne A, Curtis J, Cavender M. IN-HOSPITAL MORTALITY RISK PREDICTION FOR PERCUTANEOUS CORONARY INTERVENTIONS: AN UPDATED MODEL FROM THE NCDR CATHPCI REGISTRY. Journal Of The American College Of Cardiology 2021, 77: 1217. DOI: 10.1016/s0735-1097(21)02576-6.Peer-Reviewed Original Research
2020
CHANGES OF LEFT ATRIAL APPENDAGE ORIFICE FOLLOWING PERCUTANEOUS LEFT ATRIAL APPENDAGE CLOSURE USING THREE-DIMENSIONAL ECHOCARDIOGRAPHY
Ortiz-Leon X, Posada E, Chen W, Bregasi A, Crandall I, Pereira J, Miranda J, Akar J, Lin B, McNamara R, Freeman J, Curtis J, Arias-GodÃnez J, Sugeng L. CHANGES OF LEFT ATRIAL APPENDAGE ORIFICE FOLLOWING PERCUTANEOUS LEFT ATRIAL APPENDAGE CLOSURE USING THREE-DIMENSIONAL ECHOCARDIOGRAPHY. Journal Of The American College Of Cardiology 2020, 75: 1708. DOI: 10.1016/s0735-1097(20)32335-4.Peer-Reviewed Original Research
2007
Impact of Delay in Door-to-Needle Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction
McNamara RL, Herrin J, Wang Y, Curtis JP, Bradley EH, Magid DJ, Rathore SS, Nallamothu BK, Peterson ED, Blaney ME, Frederick P, Krumholz HM. Impact of Delay in Door-to-Needle Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction. The American Journal Of Cardiology 2007, 100: 1227-1232. PMID: 17920362, PMCID: PMC2715362, DOI: 10.1016/j.amjcard.2007.05.043.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArrhythmias, CardiacCaliforniaCohort StudiesEmergency Service, HospitalEmergency TreatmentFemaleFibrinolytic AgentsHospital MortalityHumansMaleMedical RecordsMyocardial InfarctionOutcome Assessment, Health CareRegistriesRetrospective StudiesThrombolytic TherapyTime and Motion StudiesTime FactorsConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionNeedle timeFibrinolytic therapyMyocardial infarctionHospital mortalitySymptom onsetOdds ratioReperfusion strategyAdjunctive medicationsHospital arrivalShorter doorTimely administrationNational registryRepresentative cohortPatientsMortalityInfarctionTherapyIndependent effectsCohortMinutesSmaller centersOnsetImpact of delay
2006
Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction
Bradley EH, Herrin J, Wang Y, Barton BA, Webster TR, Mattera JA, Roumanis SA, Curtis JP, Nallamothu BK, Magid DJ, McNamara RL, Parkosewich J, Loeb JM, Krumholz HM. Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction. New England Journal Of Medicine 2006, 355: 2308-2320. PMID: 17101617, DOI: 10.1056/nejmsa063117.Peer-Reviewed Original ResearchConceptsST-segment elevationBalloon timeCatheterization laboratoryMyocardial infarctionFaster doorEmergency departmentPrimary percutaneous coronary interventionHospital strategiesIntracoronary balloon inflationPercutaneous coronary interventionAcute myocardial infarctionMinority of hospitalsEmergency medicine physiciansReperfusion treatmentCoronary interventionBalloon inflationMedicine physiciansMultivariate analysisHospitalInfarctionPatientsMedicaid ServicesSignificant reductionReal-time data feedbackData feedback
2005
Hospital Improvement in Time to Reperfusion in Patients With Acute Myocardial Infarction, 1999 to 2002
McNamara RL, Herrin J, Bradley EH, Portnay EL, Curtis JP, Wang Y, Magid DJ, Blaney M, Krumholz HM, Investigators N. Hospital Improvement in Time to Reperfusion in Patients With Acute Myocardial Infarction, 1999 to 2002. Journal Of The American College Of Cardiology 2005, 47: 45-51. PMID: 16386663, PMCID: PMC1475926, DOI: 10.1016/j.jacc.2005.04.071.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionBalloon timeMin/yearNeedle timeMyocardial infarctionHospital characteristicsAcute ST-segment elevation myocardial infarctionPercutaneous coronary intervention cohortPercutaneous coronary intervention volumeElevation myocardial infarctionPercutaneous coronary interventionRetrospective observational studyFour-year study periodRapid reperfusionCoronary interventionFibrinolytic therapyHospital arrivalTherapy cohortReperfusion timeIntervention cohortNational registryIntervention volumeObservational studyHospital improvementPatients
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