2025
Predicting Agitation Events in the Emergency Department Through Artificial Intelligence
Wong A, Sapre A, Wang K, Nath B, Shah D, Kumar A, Faustino I, Desai R, Hu Y, Robinson L, Meng C, Tong G, Bernstein S, Yonkers K, Melnick E, Dziura J, Taylor R. Predicting Agitation Events in the Emergency Department Through Artificial Intelligence. JAMA Network Open 2025, 8: e258927. PMID: 40332935, PMCID: PMC12059975, DOI: 10.1001/jamanetworkopen.2025.8927.Peer-Reviewed Original ResearchConceptsED visitsEmergency departmentAgitation eventsElectronic health record dataArea under the receiver operating characteristic curvePatient-centered careHealth service utilizationPrimary outcomeHealth record dataUrban health systemED visit dataMode of arrivalPrevention of agitationOutcome of agitationDiverse patient populationsRestraint ordersCross-sectional cohortService utilizationVital signsED sitesHealth systemMain OutcomesRestraint eventsRange of predicted probabilitiesVisit dataAdaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Optimization Strategy trial
Iscoe M, Hooper C, Levy D, Buchanan L, Dziura J, Meeker D, Taylor R, D’Onofrio G, Oladele C, Sarpong D, Paek H, Wilson F, Heagerty P, Delgado M, Hoppe J, Melnick E. Adaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Optimization Strategy trial. BMJ Open 2025, 15: e098072. PMID: 39979056, PMCID: PMC11842997, DOI: 10.1136/bmjopen-2024-098072.Peer-Reviewed Original ResearchConceptsClinical decision supportMultiphase optimization strategyOpioid use disorderEmergency departmentInitiation of buprenorphineClinical decision support usePlan-Do-Study-Act cyclesLearning health system approachPlan-Do-Study-ActClinical decision support toolHealth system approachAdaptive decision supportUse disorderDecision supportAddiction treatmentPeer-reviewed journalsBuprenorphine initiationOpioid use disorder treatment initiationOpioid-related mortalityIntervention componentsED settingClinician feedbackInstitute Institutional Review BoardTreatment of opioid use disorderParticipating sites
2024
Formative evaluation of an emergency department clinical decision support system for agitation symptoms: a study protocol
Wong A, Nath B, Shah D, Kumar A, Brinker M, Faustino I, Boyce M, Dziura J, Heckmann R, Yonkers K, Bernstein S, Adapa K, Taylor R, Ovchinnikova P, McCall T, Melnick E. Formative evaluation of an emergency department clinical decision support system for agitation symptoms: a study protocol. BMJ Open 2024, 14: e082834. PMID: 38373857, PMCID: PMC10882402, DOI: 10.1136/bmjopen-2023-082834.Peer-Reviewed Original ResearchConceptsComputerised clinical decision supportED treatRestraint useExperiences of restraint useMental health-related visitsEmergency departmentPrevent agitationSystems-related factorsImprove patient experienceClinical decision support systemsRegional health systemClinical decision supportDe-escalation techniquesRandomised controlled trialsFormative evaluationPeer-reviewed journalsBest-practice guidanceAt-risk populationsCDS toolsThematic saturationED cliniciansPatient experienceED sitesHealth systemED physiciansRenalase Identified by Machine Learning Methods as A Novel Independent Predictor of Mortality in Hospitalized Patients with COVID-19
Safdar B, Sobiesk M, Bertsimas D, Nowroozpoor A, Deng Y, D’Onofrio G, Dziura J, El-Khoury J, Guo X, Simonov M, Taylor R, Wang M, Desir G. Renalase Identified by Machine Learning Methods as A Novel Independent Predictor of Mortality in Hospitalized Patients with COVID-19. Journal Of Biotechnology And Biomedicine 2024, 07 DOI: 10.26502/jbb.2642-91280139.Peer-Reviewed Original Research
2015
The Prevalence and Characteristics of Emergency Medicine Patient Use of New Media
Post LA, Vaca FE, Biroscak BJ, Dziura J, Brandt C, Bernstein SL, Taylor R, Jagminas L, D'Onofrio G. The Prevalence and Characteristics of Emergency Medicine Patient Use of New Media. JMIR MHealth And UHealth 2015, 3: e72. PMID: 26156096, PMCID: PMC4526985, DOI: 10.2196/mhealth.4438.Peer-Reviewed Original ResearchED patientsPatient useAcademic-affiliated hospitalUrban academic teaching hospitalHealth careHigh-volume EDsEmergency department settingUrban community hospitalHealth care barriersAcademic teaching hospitalCross-sectional surveyIndex visitED visitsSmartphone ownershipCare barriersDepartment settingCommunity hospitalTeaching hospitalBlack non-HispanicsPatientsAffiliate hospitalsPersonal health recordsOlder personsNon-HispanicsCare apps
2013
Point-of-Care Focused Cardiac Ultrasound for Prediction of Pulmonary Embolism Adverse Outcomes
Taylor RA, Davis J, Liu R, Gupta V, Dziura J, Moore CL. Point-of-Care Focused Cardiac Ultrasound for Prediction of Pulmonary Embolism Adverse Outcomes. Journal Of Emergency Medicine 2013, 45: 392-399. PMID: 23827166, DOI: 10.1016/j.jemermed.2013.04.014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overEchocardiographyEmergency Service, HospitalFemaleHemorrhageHospital MortalityHumansMaleMiddle AgedPoint-of-Care SystemsPredictive Value of TestsPrognosisPulmonary EmbolismRecurrenceRespiratory InsufficiencyRetrospective StudiesRisk FactorsShockVenous ThromboembolismVentricular Dysfunction, RightConceptsRight ventricular strainHospital adverse outcomesRetrospective chart reviewPulmonary embolismAdverse outcomesEmergency departmentChart reviewCardiac ultrasoundHighest positive likelihood ratioRecurrent venous thromboembolismLow negative likelihood ratioSignificant predictorsEmergency care practitionersFocused cardiac ultrasoundFOCUS examinationPositive likelihood ratioNegative likelihood ratioMajor bleedingLikelihood ratioRespiratory failureVenous thromboembolismTransthoracic echocardiographyHospital admissionIndependent predictorsVentricular strain
2012
Point‐of‐care Focused Cardiac Ultrasound for the Assessment of Thoracic Aortic Dimensions, Dilation, and Aneurysmal Disease
Taylor RA, Oliva I, Van Tonder R, Elefteriades J, Dziura J, Moore CL. Point‐of‐care Focused Cardiac Ultrasound for the Assessment of Thoracic Aortic Dimensions, Dilation, and Aneurysmal Disease. Academic Emergency Medicine 2012, 19: 244-247. PMID: 22288871, DOI: 10.1111/j.1553-2712.2011.01279.x.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAortic dilationThoracic aortic dimensionsCT angiographyTransthoracic echocardiographyAortic dissectionBland-Altman plotsAortic dimensionsEmergency departmentAortic aneurysmEmergency physiciansCardiac ultrasoundPilot studyNinety-two patientsThoracic aorta pathologyFurther prospective studiesThoracic aortic diameterThoracic aortic pathologyRetrospective pilot studySinus of ValsalvaAcademic emergency departmentCTA measurementsFocused cardiac ultrasoundRetrospective pilot analysisReference standard
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