2025
Determinants of increased muscle insulin sensitivity of exercise-trained versus sedentary normal weight and overweight individuals
Pesta D, Anadol-Schmitz E, Sarabhai T, Kamp Y, Gancheva S, Trinks N, Zaharia O, Mastrototaro L, Lyu K, Habets I, Kamp-Bruls Y, Dewidar B, Weiss J, Schrauwen-Hinderling V, Zhang D, Gaspar R, Strassburger K, Kupriyanova Y, Al-Hasani H, Szendroedi J, Schrauwen P, Phielix E, Shulman G, Roden M. Determinants of increased muscle insulin sensitivity of exercise-trained versus sedentary normal weight and overweight individuals. Science Advances 2025, 11: eadr8849. PMID: 39742483, PMCID: PMC11691647, DOI: 10.1126/sciadv.adr8849.Peer-Reviewed Original ResearchConceptsOverweight-to-obeseNormal weightEndurance-trained humansMuscle mitochondrial contentAthlete's paradoxTrained athletesExercise-trainedOverweight individualsAthletesObesity subtypesObservational studyIntramyocellular triglyceride accumulationInsulin sensitivityHigher insulin sensitivityMitochondrial contentIncreased insulin sensitivityMuscleFemale individualsIndividualsInsulin resistanceObesityMitochondrial partitioningIncreased calpainNPKC activityProtein kinase C
2018
Immune‐endocrine responses and physical performance of master athletes during the sports season
Minuzzi L, Rama L, Chupel M, Rosado F, Kuga G, Gaspar R, Muñoz V, Pauli J, Paiva A, Teixeira A. Immune‐endocrine responses and physical performance of master athletes during the sports season. Journal Of Cellular Biochemistry 2018, 120: 5551-5557. PMID: 30320909, DOI: 10.1002/jcb.27839.Peer-Reviewed Original ResearchConceptsMaster athletesTestosterone levelsImmune-endocrine responsesTestosterone/cortisol ratioLow testosterone levelsMaximal heart rateLean body massMale master athletesSports seasonMaximal oxygen consumptionCortisol ratioFat massImmunoglobulin AHeart rateBody compositionCortisol levelsPhysical performanceReduced percentageTraining seasonRegular trainingOxygen consumptionAthletesBody massMarkersAnthropometric
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