2022
Loco-regional radiosensitizing nanoparticles-in-gel augments head and neck cancer chemoradiotherapy
Bhardwaj P, Gota V, Vishwakarma K, Pai V, Chaudhari P, Mohanty B, Thorat R, Yadav S, Gurjar M, Goda JS, Banerjee R. Loco-regional radiosensitizing nanoparticles-in-gel augments head and neck cancer chemoradiotherapy. Journal Of Controlled Release 2022, 343: 288-302. PMID: 35101477, DOI: 10.1016/j.jconrel.2022.01.040.Peer-Reviewed Original Research
2020
Multifunctional Core–Shell Glyconanoparticles for Galectin-3-Targeted, Trigger-Responsive Combination Chemotherapy
Balakrishnan B, Subramanian S, Mallia MB, Repaka K, Kaur S, Chandan R, Bhardwaj P, Dash A, Banerjee R. Multifunctional Core–Shell Glyconanoparticles for Galectin-3-Targeted, Trigger-Responsive Combination Chemotherapy. Biomacromolecules 2020, 21: 2645-2660. PMID: 32484667, DOI: 10.1021/acs.biomac.0c00358.Peer-Reviewed Original ResearchConceptsCore-shell nanoparticlesTarget specific drug releaseMultivalent ligand presentationCombination drug deliveryBoronate estersDrug releaseSchiff baseMDA-MB-231 cancer cellsCitrus pectinDrug deliveryNanoparticlesPlacebo nanoparticlesProof of conceptPeriodate oxidationLigand presentationGlyconanoparticlesVivo monitoringEnhanced internalizationTarget specificityGastric tractTriple-negative MDA-MB-231 breast cancer cellsBiodistribution studiesHomotypic cellular aggregationDoxorubicinShellAdvancements in prophylactic and therapeutic nanovaccines
Bhardwaj P, Bhatia E, Sharma S, Ahamad N, Banerjee R. Advancements in prophylactic and therapeutic nanovaccines. Acta Biomaterialia 2020, 108: 1-21. PMID: 32268235, PMCID: PMC7163188, DOI: 10.1016/j.actbio.2020.03.020.Peer-Reviewed Original ResearchConceptsImmune responseConventional vaccinesSuitable immune responsePathological conditionsAntibody-mediated immunityImmune system activationStrong immune responseNon-infectious diseasesHigh antigen loadingBooster dosesLymph nodesImmunodeficiency syndromeImmune activationTreatment of cancerMultiple dosesEnhanced immunogenicityAntigen presentationForeign antigensAntigen loadingPatient complianceNovel nanovaccinesSystem activationImmune systemVaccine developmentTherapeutic potential
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply