2017
Concomitant antegrade stent grafting of the descending thoracic aorta during transverse hemiarch reconstruction for acute DeBakey I aortic dissection repair improves aortic remodeling
Sultan I, Wallen TJ, Habertheuer A, Siki M, Arnaoutakis GJ, Bavaria J, Szeto WY, Milewski R, Vallabhajosyula P. Concomitant antegrade stent grafting of the descending thoracic aorta during transverse hemiarch reconstruction for acute DeBakey I aortic dissection repair improves aortic remodeling. Journal Of Cardiac Surgery 2017, 32: 581-592. PMID: 28795434, DOI: 10.1111/jocs.13192.Peer-Reviewed Original ResearchConceptsTrue lumen diameterTEVAR groupTrue lumenThoracic aortaLumen diameterHemiarch reconstructionAortic remodelingStent graftingOpen repairAortic diameterAcute DeBakey I aortic dissectionDeBakey I aortic dissectionFalse lumen thrombosis rateThree-dimensional computed tomography scansAortic dissection repairDeBakey I dissectionsDistal aortic remodelingTotal aortic diameterFalse lumen thrombosisAbdominal aortic diameterEndovascular stent graftingEndovascular aortic repairComputed tomography scanArch tearDeBakey IAortic Regurgitation in Acute Type-A Aortic Dissection: A Clinical Classification for the Perioperative Echocardiographer in the Era of the Functional Aortic Annulus
Patel PA, Bavaria JE, Ghadimi K, Gutsche JT, Vallabhajosyula P, Ko HA, Desai ND, Mackay E, Weiss SJ, Augoustides JGT. Aortic Regurgitation in Acute Type-A Aortic Dissection: A Clinical Classification for the Perioperative Echocardiographer in the Era of the Functional Aortic Annulus. Journal Of Cardiothoracic And Vascular Anesthesia 2017, 32: 586-597. PMID: 28927697, DOI: 10.1053/j.jvca.2017.06.014.Peer-Reviewed Educational MaterialsConceptsFunctional aortic annulusAortic annulusAortic regurgitationSurgical therapyAcute Type A Aortic DissectionType A Aortic DissectionPerioperative echocardiographerAcute aortic syndromeCoronary artery involvementAortic syndromeArtery involvementAortic dissectionTransesophageal echocardiographyRoot dissectionAortic rootPatient presentationClinical classificationSurgical experienceAnatomic considerationsClinical approachRegurgitationTherapyEchocardiographersDissectionLatest literature
2016
Central Repair With Antegrade TEVAR for Malperfusion Syndromes in Acute Debakey I Aortic Dissection
Vallabhajosyula P, Gottret JP, Menon R, Sultan I, Abbas Z, Siki M, Kramer M, Pulsipher A, Naidu S, Pochettino A, Milewski K, Szeto WY, Bavaria JE. Central Repair With Antegrade TEVAR for Malperfusion Syndromes in Acute Debakey I Aortic Dissection. The Annals Of Thoracic Surgery 2016, 103: 748-755. PMID: 27666785, DOI: 10.1016/j.athoracsur.2016.06.097.Peer-Reviewed Original ResearchConceptsAcute DeBakey I aortic dissectionDeBakey I aortic dissectionTEVAR groupMalperfusion syndromeAortic dissectionStandard repairCirculatory arrestMortality rateHospital/30-day mortality ratePostoperative stroke rateRenal failure rateEnd-organ malperfusionStandard open repairEnd-organ systemDeBakey IParaplegia ratePreoperative comorbiditiesHemiarch replacementEmergent operationDistal repairOpen repairSurvival benefitThoracic aortaStroke rateCentral repair
2015
Monitoring of Allogeneic Islet Grafts in Nonhuman Primates Using MRI
Wang P, Schuetz C, Vallabhajosyula P, Medarova Z, Tena A, Wei L, Yamada K, Deng S, Markmann JF, Sachs DH, Moore A. Monitoring of Allogeneic Islet Grafts in Nonhuman Primates Using MRI. Transplantation 2015, 99: 1574-1581. PMID: 25806407, PMCID: PMC4551574, DOI: 10.1097/tp.0000000000000682.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnimalsBiomarkersBlood GlucoseContrast MediaDextransDisease Models, AnimalGraft RejectionImmunosuppressive AgentsIslets of LangerhansIslets of Langerhans TransplantationMagnetic Resonance ImagingMagnetite NanoparticlesMaleOrgan SizePapio hamadryasPredictive Value of TestsStreptozocinTime FactorsTransplantation, HomologousConceptsGraft volumeIslet graftsBlood glucosePancreatic isletsNonhuman primatesAcute graft lossAllogeneic immune rejectionAllogeneic islet graftsWithdrawal of immunosuppressionPancreatic islet graftsVivo MRIGraft lossAllogeneic isletsGraft monitoringTreatment optionsIslet lossIslet transplantationRenal capsuleAllogeneic modelAutologous modelImmune rejectionMRISecondary damageImmunosuppressionIslets
2014
Distal aortic reintervention after surgery for acute DeBakey type I or II aortic dissection: open versus endovascular repair†
Rylski B, Beyersdorf F, Desai ND, Euringer W, Siepe M, Kari FA, Vallabhajosyula P, Szeto WY, Milewski RK, Bavaria JE. Distal aortic reintervention after surgery for acute DeBakey type I or II aortic dissection: open versus endovascular repair†. European Journal Of Cardio-Thoracic Surgery 2014, 48: 258-263. PMID: 25527171, DOI: 10.1093/ejcts/ezu488.Peer-Reviewed Original ResearchConceptsDeBakey type IDistal reinterventionAortic reinterventionDissection repairEndovascular groupHospital mortalityAortic pathologyAcute aortic dissection repairAcute DeBakey type IType IAortic dissection repairDistal aortic pathologyDistal aortic reinterventionOpen repair patientsEndovascular patientsLate reinterventionSpinal ischaemiaAcute dissectionEndovascular repairAortic dissectionConsecutive patientsEndovascular approachSurgical repairTertiary centerMedian timeImpact of timing on major complications after thoracic endovascular aortic repair for acute type B aortic dissection
Desai ND, Gottret JP, Szeto WY, McCarthy F, Moeller P, Menon R, Jackson B, Vallabhajosyula P, Wang GJ, Fairman R, Bavaria JE. Impact of timing on major complications after thoracic endovascular aortic repair for acute type B aortic dissection. Journal Of Thoracic And Cardiovascular Surgery 2014, 149: s151-s156. PMID: 25466855, DOI: 10.1016/j.jtcvs.2014.10.105.Peer-Reviewed Original ResearchConceptsType B dissectionEndovascular aortic repairB dissectionImpact of timingAortic repairAortic dissectionMedical therapyAcute type B aortic dissectionComplicated type B dissectionType B aortic dissectionB aortic dissectionHours of presentationOnset of symptomsRisk of complicationsWeeks of presentationOverall survivalSevere complicationsSurvival benefitMajor complicationsSuch patientsAcute patientsOpen surgeryRetrograde typeClinical registryTEVARLong-term results of aggressive hemiarch replacement in 534 patients with type A aortic dissection
Rylski B, Milewski RK, Bavaria JE, Vallabhajosyula P, Moser W, Szeto WY, Desai ND. Long-term results of aggressive hemiarch replacement in 534 patients with type A aortic dissection. Journal Of Thoracic And Cardiovascular Surgery 2014, 148: 2981-2985. PMID: 25112930, DOI: 10.1016/j.jtcvs.2014.05.093.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAgedAged, 80 and overAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationFemaleHospital MortalityHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPostoperative ComplicationsReoperationRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeConceptsDeBakey type IDistal aortic reinterventionHemiarch replacementAcute typeAortic reinterventionAortic dissectionDeBakey type I dissectionAdverse aortic eventsType I dissectionAortic arch aneurysmLong-term resultsType IAortic wall tissueDistal reinterventionHospital mortalityAortic eventsReoperation rateTotal archArch aneurysmIndependent predictorsReinterventionStudy populationMarfan syndromePatientsLower mortalityModeling of predissection aortic size in acute type A dissection: More than 90% fail to meet the guidelines for elective ascending replacement
Rylski B, Branchetti E, Bavaria JE, Vallabhajosyula P, Szeto WY, Milewski RK, Desai ND. Modeling of predissection aortic size in acute type A dissection: More than 90% fail to meet the guidelines for elective ascending replacement. Journal Of Thoracic And Cardiovascular Surgery 2014, 148: 944-948.e1. PMID: 24998700, DOI: 10.1016/j.jtcvs.2014.05.050.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAgedAortic AneurysmAortic DissectionAortographyBlood Vessel Prosthesis ImplantationEchocardiography, TransesophagealElective Surgical ProceduresFemaleGermanyGuideline AdherenceHumansIncidenceMaleMiddle AgedPatient SelectionPractice Guidelines as TopicPredictive Value of TestsRetrospective StudiesRisk FactorsTomography, X-Ray ComputedConceptsDissection onsetAcute typeAortic dissectionAorta diameterAortic diameterAscending aortaPreoperative computed tomography angiogramsComputed tomography angiogramAortic dissection onsetAcute dissectionAortic replacementAortic dilatationAortic sizeTomography angiogramBiochemical predictorsCurrent guidelinesPatientsDiameter increase ratePredissectionDissectionAortaMarfanOnsetWomenAdditional researchAortic Valve Morphology Determines the Presentation and Surgical Approach to Acute Type A Aortic Dissection
Rylski B, Desai ND, Bavaria JE, Vallabhajosyula P, Moser W, Pochettino A, Szeto WY, Milewski RK. Aortic Valve Morphology Determines the Presentation and Surgical Approach to Acute Type A Aortic Dissection. The Annals Of Thoracic Surgery 2014, 97: 1991-1997. PMID: 24786861, DOI: 10.1016/j.athoracsur.2013.12.090.Peer-Reviewed Original ResearchConceptsTricuspid aortic valveBAV patientsAortic valve morphologyHospital mortalityAortic dissectionTAV patientsAcute Type A Aortic DissectionBicuspid aortic valve syndromeType A Aortic DissectionValve morphologyA Aortic DissectionSevere aortic insufficiencyTotal arch replacementAortic root replacementAortic root repairMedian followProximal reoperationAcute typeArch replacementCardiogenic shockAortic insufficiencyRoot replacementAortic diameterAorta diameterSurgical approach
2013
Antegrade thoracic stent grafting during repair of acute Debakey type I dissection promotes distal aortic remodeling and reduces late open distal reoperation rate
Vallabhajosyula P, Szeto WY, Pulsipher A, Desai N, Menon R, Moeller P, Musthaq S, Pochettino A, Bavaria JE. Antegrade thoracic stent grafting during repair of acute Debakey type I dissection promotes distal aortic remodeling and reduces late open distal reoperation rate. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 942-950. PMID: 24332104, DOI: 10.1016/j.jtcvs.2013.10.047.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAortic Aneurysm, ThoracicAortic DissectionBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationEndovascular ProceduresFemaleHospital MortalityHumansKaplan-Meier EstimateMaleMiddle AgedPlastic Surgery ProceduresPostoperative ComplicationsReoperationRetrospective StudiesStentsTime FactorsTreatment OutcomeConceptsDistal aortic remodelingStandard open repairOpen repairAortic remodelingStented groupDissection repairReoperation rateAcute DeBakey type IDeBakey type I dissectionStandard groupAntegrade cerebral perfusionAortic reintervention ratesAortic reoperation ratesDeBakey type IDistal aortic reoperationFalse lumen obliterationType I dissectionCirculatory arrest timeHospital/30-day mortalityStent-graft deploymentActuarial survivalAortic reoperationHemiarch reconstructionMidterm mortalityMidterm outcomes