2018
Management of Patients With Coronary Artery Malperfusion Secondary to Type A Aortic Dissection
Kreibich M, Bavaria JE, Branchetti E, Brown CR, Chen Z, Khurshan F, Siki M, Vallabhajosyula P, Szeto WY, Desai ND. Management of Patients With Coronary Artery Malperfusion Secondary to Type A Aortic Dissection. The Annals Of Thoracic Surgery 2018, 107: 1174-1180. PMID: 30444990, DOI: 10.1016/j.athoracsur.2018.09.065.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCohort StudiesCoronary Artery BypassCoronary Artery DiseaseCoronary CirculationFemaleGermanyHeart Arrest, InducedHospital MortalityHospitals, UniversityHumansKaplan-Meier EstimateLength of StayMaleMiddle AgedPostoperative ComplicationsPrognosisRetrospective StudiesRisk AssessmentStatistics, NonparametricSurvival AnalysisTreatment OutcomeConceptsCoronary artery malperfusionType B patientsType C patientsAntegrade cardioplegiaC patientsB patientsAortic dissectionCoronary ostiumDissection flapCA diseaseA Aortic DissectionType C lesionsManagement of patientsType B lesionsLong-term survivalCA bypassBypass GraftingPerioperative mortalityC lesionsComplete avulsionB lesionsLandmark analysisMalperfusionSuture repairPatients
2017
Long-term outcome of surgical cryoablation for refractory ventricular tachycardia in patients with non-ischemic cardiomyopathy
Liang JJ, Betensky BP, Muser D, Zado ES, Anter E, Desai ND, Callans DJ, Deo R, Frankel DS, Hutchinson MD, Lin D, Riley MP, Schaller RD, Supple GE, Santangeli P, Acker MA, Bavaria JE, Szeto WY, Vallabhajosyula P, Marchlinski FE, Dixit S. Long-term outcome of surgical cryoablation for refractory ventricular tachycardia in patients with non-ischemic cardiomyopathy. EP Europace 2017, 20: e30-e41. PMID: 28402404, DOI: 10.1093/europace/eux029.Peer-Reviewed Original ResearchConceptsNon-ischemic cardiomyopathyRadiofrequency catheter ablationLong-term outcomesSurgical ablationVT refractoryElectrophysiology labSocial Security Death IndexArrhythmia-related deathMapping/ablationPrimary surgical ablationRefractory ventricular tachycardiaVentricular tachycardia refractoryVT-free survivalLong-term survivalSurgical cryoablationICD interrogationConsecutive patientsEntire followCatheter ablationICD shocksTachycardia refractoryVT recurrenceOffice visitsTherapeutic optionsConsecutive pts
2016
Valve Selection in End-Stage Renal Disease: Should It Always Be Biological?
Williams ML, Bavaria JE, Acker MA, Desai ND, Vallabhajosyula P, Hargrove WC, Atluri P, Szeto WY. Valve Selection in End-Stage Renal Disease: Should It Always Be Biological? The Annals Of Thoracic Surgery 2016, 102: 1531-1535. PMID: 27544289, DOI: 10.1016/j.athoracsur.2016.04.092.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAnticoagulantsAortic ValveBioprosthesisCalcinosisContraindicationsEndocarditisHeart Valve DiseasesHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansKaplan-Meier EstimateKidney Failure, ChronicMiddle AgedMitral ValvePostoperative ComplicationsProportional Hazards ModelsProsthesis-Related InfectionsRenal DialysisRetrospective StudiesThrombophiliaConceptsEnd-stage renal diseaseValve replacementProportional hazards modelESRD patientsMechanical valvesRenal diseaseHazards modelImproved long-term survivalCox proportional hazards modelAortic valve replacementMechanical valve replacementMitral valve replacementKaplan-Meier methodLong-term survivalValve selectionESRD populationPatient ageUnadjusted survivalImproved survivalPatient populationPatientsSurvivalDiseaseMinimal differencesYearsAt the Root of the Repair Debate: Outcomes After Elective Aortic Root Replacements for Aortic Insufficiency With Aneurysm
McCarthy FH, Bavaria JE, McDermott KM, Moeller P, Spragan D, Hoedt A, Dibble T, Savino D, Williams ML, Vallabhajosyula P, Szeto WY, Desai ND. At the Root of the Repair Debate: Outcomes After Elective Aortic Root Replacements for Aortic Insufficiency With Aneurysm. The Annals Of Thoracic Surgery 2016, 102: 1199-1205. PMID: 27261085, DOI: 10.1016/j.athoracsur.2016.03.071.Peer-Reviewed Original ResearchMeSH KeywordsAdultAortic Aneurysm, ThoracicAortic Valve InsufficiencyBlood Vessel Prosthesis ImplantationCause of DeathDatabases, FactualElective Surgical ProceduresFemaleFollow-Up StudiesHeart Valve Prosthesis ImplantationHospital MortalityHumansKaplan-Meier EstimateMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentSurvival AnalysisTreatment OutcomeConceptsModerate aortic insufficiencySevere aortic insufficiencyAortic insufficiencyLong-term survivalRoot replacementWorse survivalAI patientsDecreased long-term survivalElective aortic root replacementWorse long-term survivalPreoperative aortic insufficiencyPreoperative renal failureAortic root replacementAppropriate therapeutic strategiesGreater aortic insufficiencyTiming of interventionUnited States populationRenal failureYounger patientsMultivariable predictorsSimilar patientsAortic aneurysmSingle institutionInclusion criteriaSimilar survival
2013
Moderate mitral regurgitation in aortic root replacement surgery: Comparing mitral repair with no mitral repair
McCarthy FH, Desai ND, Fox Z, George J, Moeller P, Vallabhajosyula P, Szeto WY, Bavaria JE. Moderate mitral regurgitation in aortic root replacement surgery: Comparing mitral repair with no mitral repair. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 938-941. PMID: 24035374, DOI: 10.1016/j.jtcvs.2013.07.056.Peer-Reviewed Original ResearchMeSH KeywordsAortic Valve InsufficiencyAortic Valve StenosisComorbidityHeart FailureHeart Valve Prosthesis ImplantationHumansIncidenceMitral Valve InsufficiencyPatient SelectionPennsylvaniaPostoperative ComplicationsRetrospective StudiesRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsAortic root replacement surgeryModerate mitral regurgitationMitral repair groupAortic root replacementMitral regurgitationMitral repairReplacement surgeryRoot replacementRepair groupNew York Heart Association III/IVAcceptable operative riskGreater mitral regurgitationPreoperative mitral regurgitationPostoperative renal failureMitral valve pathologyMitral valve repairLong-term survivalBenefits of interventionsCrossclamp timeMitral reinterventionOperative riskRenal failureHeart failureValve pathologyValve repair
2007
Vascularized composite islet-kidney transplantation in a miniature swine model
Vallabhajosyula P, Griesemer A, Yamada K, Sachs DH. Vascularized composite islet-kidney transplantation in a miniature swine model. Cell Biochemistry And Biophysics 2007, 48: 201-207. PMID: 17709890, DOI: 10.1007/s12013-007-0027-4.Peer-Reviewed Original ResearchConceptsThymic tissueIslet equivalentsEnd-stage diabetic nephropathyType I diabetic patientsAllogeneic thymic tissueRecipient body weightLong-term toleranceLong-term survivalMiniature swine modelKidney allograftsMHC barriersDiabetic nephropathyAllogeneic isletsAllogeneic transplantationDiabetic hyperglycemiaDiabetic patientsThymic componentsTreatment regimensPortal veinRenal capsuleOrgan transplantsAutologous isletsMiniature swineTransplantationBody weight